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MX2017016828A - Vacuna conjugada neumococica polivalente. - Google Patents

Vacuna conjugada neumococica polivalente.

Info

Publication number
MX2017016828A
MX2017016828A MX2017016828A MX2017016828A MX2017016828A MX 2017016828 A MX2017016828 A MX 2017016828A MX 2017016828 A MX2017016828 A MX 2017016828A MX 2017016828 A MX2017016828 A MX 2017016828A MX 2017016828 A MX2017016828 A MX 2017016828A
Authority
MX
Mexico
Prior art keywords
conjugate vaccine
pneumococcal conjugate
pneumococcal
multivalent pneumococcal
composition
Prior art date
Application number
MX2017016828A
Other languages
English (en)
Other versions
MX389480B (es
Inventor
Venkat Matur Ramesh
Thirumeni Nagarajan
Burki Rajendra
Dev Mantena Narender
Datla Mahima
Original Assignee
Biological E Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biological E Ltd filed Critical Biological E Ltd
Publication of MX2017016828A publication Critical patent/MX2017016828A/es
Publication of MX389480B publication Critical patent/MX389480B/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6415—Toxins or lectins, e.g. clostridial toxins or Pseudomonas exotoxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Physiology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se relaciona con una composición de vacuna conjugada neumocócica (PCV) polivalente que comprende: 1) al menos 12 polisacáridos capsulares seleccionados de los serotipos 1, 3, 4, 5, 6B, 7F, 9N, 9V, 15B, 14, 18C, 19A, 19F, 22F, 23F y 33F de S. pneumoniae activados con CDAP y conjugados con una proteína portadora seleccionada de la CRM197, la proteína A de superficie neumocócica (PspA), la proteína de adhesina neumocócica (PsaA) o una combinación de las mismas y 2) un portador farmacéuticamente aceptable, en donde la composición no contiene un polisacárido capsular proveniente del serotipo 6A.
MX2017016828A 2015-06-23 2016-06-21 Vacuna conjugada neumococica polivalente. MX389480B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN3140CH2015 2015-06-23
PCT/IN2016/000157 WO2016207905A2 (en) 2015-06-23 2016-06-21 Multivalent pneumococcal conjugate vaccine

Publications (2)

Publication Number Publication Date
MX2017016828A true MX2017016828A (es) 2018-09-18
MX389480B MX389480B (es) 2025-03-20

Family

ID=56738144

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017016828A MX389480B (es) 2015-06-23 2016-06-21 Vacuna conjugada neumococica polivalente.

Country Status (22)

Country Link
US (1) US11147863B2 (es)
EP (1) EP3313436B1 (es)
JP (1) JP6808658B2 (es)
CN (1) CN107810010A (es)
AU (1) AU2016285017B2 (es)
BR (1) BR112017028130A2 (es)
CY (1) CY1123838T1 (es)
DK (1) DK3313436T3 (es)
EA (1) EA037373B1 (es)
ES (1) ES2857474T3 (es)
HR (1) HRP20210373T1 (es)
HU (1) HUE053272T2 (es)
LT (1) LT3313436T (es)
MX (1) MX389480B (es)
PL (1) PL3313436T3 (es)
PT (1) PT3313436T (es)
RS (1) RS61440B1 (es)
SA (1) SA517390539B1 (es)
SI (1) SI3313436T1 (es)
SM (1) SMT202100121T1 (es)
WO (1) WO2016207905A2 (es)
ZA (1) ZA201708713B (es)

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AU2017336806B2 (en) * 2016-09-30 2024-06-27 Biological E Limited Multivalent pneumococcal vaccine compositions comprising polysaccharide-protein conjugates
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
ES3024474T3 (en) 2016-12-30 2025-06-04 Vaxcyte Inc Polypeptide-antigen conjugates with non-natural amino acids
EP3634481A4 (en) * 2017-06-10 2021-07-21 Inventprise, LLC. MULTIVALENT CONJUGATE VACCINES WITH BIVALENT OR MULTIVALENT CONJUGATE POLYSACCHARIDES THAT CONFIRM ENHANCED IMMUNOGENICITY AND AVIDITY
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
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AU2019215216B2 (en) 2018-02-05 2025-04-17 Sk Bioscience Co., Ltd. Multivalent pneumococcal polysaccharide-protein conjugate composition
AU2019256218B2 (en) 2018-04-18 2025-10-16 Sk Bioscience Co., Ltd. Streptococcus pneumoniae capsular polysaccharides and immunogenic conjugate thereof
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GEP20247633B (en) 2018-12-19 2024-06-25 Merck Sharp & Dohme Llc Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
EP3900739A1 (en) 2020-04-21 2021-10-27 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Synthetic streptococcus pneumoniae saccharide conjugates to conserved membrane protein

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Also Published As

Publication number Publication date
HRP20210373T1 (hr) 2021-04-30
ZA201708713B (en) 2019-08-28
SMT202100121T1 (it) 2021-05-07
HUE053272T2 (hu) 2021-06-28
RS61440B1 (sr) 2021-03-31
PL3313436T3 (pl) 2021-06-14
EP3313436B1 (en) 2020-12-23
JP2018518512A (ja) 2018-07-12
ES2857474T3 (es) 2021-09-29
AU2016285017B2 (en) 2022-03-03
WO2016207905A3 (en) 2017-02-09
SA517390539B1 (ar) 2021-05-24
AU2016285017A1 (en) 2018-01-04
MX389480B (es) 2025-03-20
JP6808658B2 (ja) 2021-01-06
EA037373B1 (ru) 2021-03-22
SI3313436T1 (sl) 2021-09-30
BR112017028130A2 (pt) 2018-08-28
CN107810010A (zh) 2018-03-16
EP3313436A2 (en) 2018-05-02
LT3313436T (lt) 2021-06-10
DK3313436T3 (da) 2021-03-08
US11147863B2 (en) 2021-10-19
PT3313436T (pt) 2021-02-25
CY1123838T1 (el) 2022-05-27
CA2989230A1 (en) 2016-12-29
EA201890431A1 (ru) 2018-06-29
WO2016207905A2 (en) 2016-12-29
US20190240308A1 (en) 2019-08-08

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