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MX2017012272A - Solucion para inhalacion de tiotropio para nebulizacion. - Google Patents

Solucion para inhalacion de tiotropio para nebulizacion.

Info

Publication number
MX2017012272A
MX2017012272A MX2017012272A MX2017012272A MX2017012272A MX 2017012272 A MX2017012272 A MX 2017012272A MX 2017012272 A MX2017012272 A MX 2017012272A MX 2017012272 A MX2017012272 A MX 2017012272A MX 2017012272 A MX2017012272 A MX 2017012272A
Authority
MX
Mexico
Prior art keywords
nebulization
inhalation solution
tiotropium
subject
pharmaceutical composition
Prior art date
Application number
MX2017012272A
Other languages
English (en)
Other versions
MX377175B (es
Inventor
Dhuppad Ulhas
Dhatrak Chandrakant
Chaudhari Sunil
Rajurkar Suresh
Koppenhagen Franciscus
Kasliwal Alkesh
Original Assignee
Glenmark Specialty Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Specialty Sa filed Critical Glenmark Specialty Sa
Publication of MX2017012272A publication Critical patent/MX2017012272A/es
Publication of MX377175B publication Critical patent/MX377175B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a una composición farmacéutica estéril que comprende tiotropio o una de sus sales farmacéuticamente aceptables, para inhalación por medio de nebulización a un sujeto (por ejemplo, un ser humano). La invención también se refiere a un proceso para preparar la composición farmacéutica y su uso en el tratamiento de enfermedades respiratorias tales como enfermedad pulmonar obstructiva crónica (EPOC) en un sujeto.
MX2017012272A 2015-05-18 2016-05-17 Solucion para inhalacion de tiotropio, administrada en forma nebulizada y el uso de la misma para tratar enfermedad pulmonar obstructiva crónica (epoc). MX377175B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1945MU2015 2015-05-18
PCT/IB2016/000783 WO2016185282A1 (en) 2015-05-18 2016-05-17 Tiotropium inhalation solution for nebulization

Publications (2)

Publication Number Publication Date
MX2017012272A true MX2017012272A (es) 2018-06-19
MX377175B MX377175B (es) 2025-03-07

Family

ID=56178395

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017012272A MX377175B (es) 2015-05-18 2016-05-17 Solucion para inhalacion de tiotropio, administrada en forma nebulizada y el uso de la misma para tratar enfermedad pulmonar obstructiva crónica (epoc).

Country Status (16)

Country Link
US (1) US9757365B2 (es)
EP (1) EP3297607B1 (es)
JP (1) JP6782706B2 (es)
KR (2) KR20180042160A (es)
CN (2) CN107995861A (es)
AU (1) AU2016264961B2 (es)
BR (1) BR112017020039A2 (es)
CA (1) CA2986839C (es)
EA (1) EA036707B1 (es)
ES (1) ES2826562T3 (es)
MX (1) MX377175B (es)
MY (1) MY188179A (es)
PH (1) PH12017502087A1 (es)
SG (1) SG10201912198WA (es)
WO (1) WO2016185282A1 (es)
ZA (1) ZA201706165B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10653683B2 (en) 2015-05-18 2020-05-19 Glenmark Specialty S.A. Tiotropium inhalation solution for nebulization
US9987260B2 (en) * 2015-05-18 2018-06-05 Glenmark Specialty S.A. Tiotropium inhalation solution for nebulization
EA201990605A1 (ru) * 2016-10-14 2019-10-31 Распыляемые композиции тиотропия и формотерола
CN109963557A (zh) * 2016-11-16 2019-07-02 格兰马克专业公司 雾化的噻托铵
US20190290633A1 (en) * 2017-10-27 2019-09-26 Nephron Pharmaceuticals Corporation Tiotropium Inhalation Solution for Nebulization
US20190231769A1 (en) 2017-10-27 2019-08-01 Nephron Pharmaceuticals Corporation Tiotropium Inhalation Solution for Nebulization
WO2019142214A1 (en) 2018-01-19 2019-07-25 Cipla Limited Pharmaceutical composition comprising tiotropium for inhalation
CN110876722A (zh) * 2018-09-06 2020-03-13 天津金耀集团有限公司 一种含有表面活性剂的噻托溴铵奥达特罗喷雾剂
CN110876807A (zh) * 2018-09-06 2020-03-13 天津金耀集团有限公司 一种含有表面活性剂的抗胆碱能药物的喷雾剂
CN110876720A (zh) * 2018-09-06 2020-03-13 天津金耀集团有限公司 依地酸盐恰当改变噻托溴铵喷雾剂表面张力的应用
CN110876721A (zh) * 2018-09-06 2020-03-13 天津金耀集团有限公司 一种含有表面活性剂的噻托溴铵喷雾剂

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (de) 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US20030215396A1 (en) * 1999-09-15 2003-11-20 Boehringer Ingelheim Pharma Kg Method for the production of propellant gas-free aerosols from aqueous medicament preparations
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
US6908928B2 (en) 2000-10-12 2005-06-21 Bi Pharma Kg. Crystalline tiotropium bromide monohydrate, processes for the preparation thereof, and pharmaceutical compositions
US20020111363A1 (en) 2000-10-31 2002-08-15 Karin Drechsel Inhalable formulation of a solution containing a tiotropium salt
US20020137764A1 (en) * 2000-10-31 2002-09-26 Karin Drechsel Inhalable formulation of a solution containing a tiotropium salt
US20020189610A1 (en) * 2001-02-01 2002-12-19 Karl-Heinz Bozung Pharmaceutical compositions containing an ipratropium salt and a betamimetic
US6702997B2 (en) * 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
JP2003221335A (ja) * 2001-10-26 2003-08-05 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
US20040019073A1 (en) 2002-04-11 2004-01-29 Boehringer Ingelheim Pharma Gmbh Co. Kg Aerosol formulation for inhalation containing a tiotropium salt
US20050058606A1 (en) * 2002-12-16 2005-03-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropium containing HFC solution formulations
GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
US20070088030A1 (en) * 2005-10-10 2007-04-19 Barbara Niklaus-Humke Aerosol formulations for the inhalation of beta-agonists
US20070098644A1 (en) * 2005-10-31 2007-05-03 Richie's Pharmacy And Medical Supply, Incorporated Delivery of a combination therapy for asthma and chronic obstructive pulmonary disease
CN103269694A (zh) * 2010-10-12 2013-08-28 西普拉有限公司 药物组合物
WO2013127738A1 (de) * 2012-02-28 2013-09-06 Boehringer Ingelheim International Gmbh Neue treibgashaltige tiotropium-formulierung
GB201507686D0 (en) 2015-05-05 2015-06-17 Norton Healthcare Ltd A stable tiotropium nebuliser solution

Also Published As

Publication number Publication date
ZA201706165B (en) 2019-02-27
PH12017502087B1 (en) 2018-04-30
CN113694045A (zh) 2021-11-26
BR112017020039A2 (pt) 2018-06-05
WO2016185282A1 (en) 2016-11-24
JP6782706B2 (ja) 2020-11-11
EA036707B1 (ru) 2020-12-10
KR20180042160A (ko) 2018-04-25
CA2986839C (en) 2021-06-15
US9757365B2 (en) 2017-09-12
MX377175B (es) 2025-03-07
ES2826562T3 (es) 2021-05-18
CA2986839A1 (en) 2016-11-24
MY188179A (en) 2021-11-24
EA201791780A1 (ru) 2018-04-30
AU2016264961B2 (en) 2021-09-09
KR20210095970A (ko) 2021-08-03
EP3297607B1 (en) 2020-07-22
AU2016264961A1 (en) 2017-12-14
HK1251451A1 (en) 2019-02-01
SG10201912198WA (en) 2020-02-27
PH12017502087A1 (en) 2018-04-30
US20160339003A1 (en) 2016-11-24
CN107995861A (zh) 2018-05-04
JP2018515428A (ja) 2018-06-14
EP3297607A1 (en) 2018-03-28

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