[go: up one dir, main page]

MX2017010505A - Inmunoensayo homogeneo con compensacion para señal de fondo. - Google Patents

Inmunoensayo homogeneo con compensacion para señal de fondo.

Info

Publication number
MX2017010505A
MX2017010505A MX2017010505A MX2017010505A MX2017010505A MX 2017010505 A MX2017010505 A MX 2017010505A MX 2017010505 A MX2017010505 A MX 2017010505A MX 2017010505 A MX2017010505 A MX 2017010505A MX 2017010505 A MX2017010505 A MX 2017010505A
Authority
MX
Mexico
Prior art keywords
compensation
immunoensay
homogeneo
fund
signal
Prior art date
Application number
MX2017010505A
Other languages
English (en)
Inventor
VSN YERRAMILLI Murthy
Xie Hongzhi
Wayne PATCH Daniel
Farace Giosi
Original Assignee
Idexx Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56689082&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2017010505(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Idexx Lab Inc filed Critical Idexx Lab Inc
Publication of MX2017010505A publication Critical patent/MX2017010505A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01049Glucose-6-phosphate dehydrogenase (1.1.1.49)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/902Oxidoreductases (1.)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Se describen inmunoensayos homogéneos que permiten la compensación de señales de fondo, inherentes en las muestras y reactivos. El uso de los inmunoensayos homogéneos para la detección o la presencia o cantidad de Dimetil-Arginina simétrica (SDMA) en las muestras biológicas. Reactivos y kits para llevar a cabo los ensayos.
MX2017010505A 2015-02-20 2016-02-19 Inmunoensayo homogeneo con compensacion para señal de fondo. MX2017010505A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562118832P 2015-02-20 2015-02-20
PCT/US2016/018667 WO2016134251A1 (en) 2015-02-20 2016-02-19 Homogenous immunoassay with compensation for background signal

Publications (1)

Publication Number Publication Date
MX2017010505A true MX2017010505A (es) 2017-11-13

Family

ID=56689082

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017010505A MX2017010505A (es) 2015-02-20 2016-02-19 Inmunoensayo homogeneo con compensacion para señal de fondo.

Country Status (17)

Country Link
US (3) US10775365B2 (es)
EP (2) EP3259593B1 (es)
JP (2) JP6896637B2 (es)
KR (2) KR102492243B1 (es)
CN (2) CN113699125A (es)
AR (1) AR103745A1 (es)
AU (2) AU2016219847B2 (es)
BR (1) BR112017017719A2 (es)
CA (2) CA2977062A1 (es)
ES (1) ES2936294T3 (es)
FI (1) FI3259593T3 (es)
HU (1) HUE060884T2 (es)
MX (1) MX2017010505A (es)
PL (1) PL3259593T3 (es)
TW (1) TWI721966B (es)
WO (1) WO2016134251A1 (es)
ZA (1) ZA201705365B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016219847B2 (en) * 2015-02-20 2022-03-10 Idexx Laboratories, Inc. Homogenous immunoassay with compensation for background signal
EP3697499A4 (en) * 2017-10-19 2021-07-21 IDEXX Laboratories, Inc. DETECTION OF SYMMETRICAL DIMETHYLARGININE
US10745492B1 (en) * 2019-04-03 2020-08-18 Ark Diagnostics, Inc. Antibodies to symmetrically dimethylated arginine analytes and use thereof
CA3168170A1 (en) * 2020-03-09 2021-09-16 Pamela Ann Cacavas Method for removing interfering components of a liquid sample prior to dispensing same on a chemical reagent test slide
WO2025205769A1 (ja) * 2024-03-26 2025-10-02 富士フイルム株式会社 α-アミラーゼと対称性ジメチルアルギニンとのコンジュゲート、およびその応用

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3875011A (en) * 1972-11-06 1975-04-01 Syva Co Enzyme immunoassays with glucose-6-phosphate dehydrogenase
US4341866A (en) * 1980-06-02 1982-07-27 Syva Company Antienzyme termination in enzyme immunoassays
DE3134787A1 (de) 1981-09-02 1983-03-10 Boehringer Mannheim Gmbh, 6800 Mannheim Creatinin-antikoerper
IT1199088B (it) * 1984-03-09 1988-12-30 Miles Italiana Saggio di legame specifico mediante impiego di anti-g6pdh come marcante
US4818703A (en) 1985-10-23 1989-04-04 Pizzolante John M Stabilized alkaline picrate reagent for jaffe creatinine determination
US6461825B1 (en) * 1987-09-30 2002-10-08 Sanofi (Societe Anonyme) Immunometric assay kit and method applicable to whole cells
EP0356160A3 (en) 1988-08-24 1991-09-11 The Board Of Trustees Of The Leland Stanford Junior University Capillary device
EP0399127A1 (en) * 1989-05-23 1990-11-28 Pharmacia ENI Diagnostics Inc. Homogeneous immunochemical method for determining haptens by means of ion selective electrodes
US5726010A (en) 1991-07-31 1998-03-10 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US6455288B1 (en) * 1993-04-08 2002-09-24 Dade Behring Marburg Gmbh Homogeneous immunoassays using mutant glucose-6-phosphate dehydrogenases
US5972703A (en) * 1994-08-12 1999-10-26 The Regents Of The University Of Michigan Bone precursor cells: compositions and methods
US5804452A (en) 1995-04-27 1998-09-08 Quidel Corporation One step urine creatinine assays
AU7269098A (en) 1997-05-01 1998-11-24 Cooke Pharma, Inc. Cardiovascular disease risk assessment
US6736957B1 (en) 1997-10-16 2004-05-18 Abbott Laboratories Biosensor electrode mediators for regeneration of cofactors and process for using
US6358699B1 (en) 1999-02-05 2002-03-19 Cooke Pharma Assay for asymmetrical NG, NG dimethyl-l-arginine
US6699673B2 (en) 1999-12-22 2004-03-02 The Research Foundation Of State University Of New York Protein methylarginine-specific antibodies
EP1299398A1 (en) * 2000-07-06 2003-04-09 Fal Diagnostics Methods and kits for the detection of arginine compounds
EP1301790B1 (en) 2000-07-12 2008-04-09 Naser, Werner, Dr. Direct assessment of analyte to reference molecule ratios
DE10040904A1 (de) 2000-08-18 2002-02-28 Boeger Rainer H Verfahren und Mittel zum Nachweis einer Wahrscheinlichkeit zukünftigen Fortschreitens von Gefässerkrankungen
US6601006B2 (en) * 2000-12-22 2003-07-29 Idexx Laboratories, Inc. Methods for the calibration of analyte assays
US7241856B2 (en) 2003-06-02 2007-07-10 Pentron Clinical Technologies Llc Dental resins, dental composite materials, and method of manufacture thereof
FR2824825B1 (fr) 2001-05-15 2005-05-06 Servier Lab Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP4214271B2 (ja) 2002-10-15 2009-01-28 アークレイ株式会社 クレアチニン測定用試験片
US7501053B2 (en) 2002-10-23 2009-03-10 Abbott Laboratories Biosensor having improved hematocrit and oxygen biases
WO2004046314A2 (en) 2002-11-15 2004-06-03 The Board Of Trustees Of The Leland Stanford Junior University Methods for detecting asymmetric dimethylarginine in a biological sample
US20050148029A1 (en) 2003-09-29 2005-07-07 Biosite, Inc. Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes
US6991911B2 (en) 2003-12-15 2006-01-31 Dade Behring Inc. Assay for entactogens
US7813880B2 (en) 2004-03-25 2010-10-12 University Of Maryland, Baltimore Apparatus and method for providing optimal concentrations for medication infusions
WO2005098439A2 (en) 2004-03-30 2005-10-20 Whatman, Inc. Lateral flow format, materials and mehtods
US7220842B2 (en) 2004-04-05 2007-05-22 Dade Behring Inc. Immunoassays for buprenorphine and norbuprenorphine
US20060046273A1 (en) * 2004-08-27 2006-03-02 Lin-Zhi International Inc. Homogeneous enzyme immunoassay for oral fluid
EP1666884B1 (en) 2004-11-04 2009-04-01 GermedIQ Forschungs- und Entwicklungsgesellschaft mbH Method for determination of arginine, methylated arginines and derivatives thereof
CA2775655C (en) * 2005-01-20 2014-03-25 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Multiplexed analysis for determining a serodiagnosis of viral infection
US7879979B2 (en) * 2005-01-21 2011-02-01 Alere International Arginine analogs, and methods for their synthesis and use
US7723127B2 (en) 2005-03-03 2010-05-25 Novx Systems Inc. Immunoassay with extended dynamic range
US20090053741A1 (en) * 2005-03-30 2009-02-26 Patrick John Thompson Vallance Assay for measuring asymmetric methylarginine in a biological sample
DK1877101T3 (en) 2005-04-28 2017-01-09 Ventana Med Syst Inc ENZYMES CONJUGATED TO ANTIBODIES THROUGH A PEG hetero LINKER
EP1946121A2 (en) 2005-10-27 2008-07-23 Yale University, Inc. Urinary proteomic biomarker patterns in preeclampsia
DE102005060057A1 (de) 2005-12-15 2007-06-28 Kellner, Karl-Heinz, Dr. Sandwich-Immunoassay für kleine Haptenmoleküle
JP2007176872A (ja) 2005-12-28 2007-07-12 Sentan Seimei Kagaku Kenkyusho:Kk アシンメトリックジメチルアルギニンを認識する抗体及びその製造方法並びに翻訳後修飾アミノ酸含有タンパク質の検出方法
ES2392629T3 (es) * 2006-03-02 2012-12-12 Perkinelmer Health Sciences, Inc. Métodos de distinción de isómeros mediante espectrometría de masas
WO2008154457A1 (en) 2007-06-08 2008-12-18 Ark Diagnosties, Inc. Topiramate immunoassays
FR2919063B1 (fr) 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal.
CN101932722A (zh) 2007-12-05 2010-12-29 伦敦王室学院 方法和组合物
HUE051130T2 (hu) 2008-08-07 2021-03-01 Idexx Lab Inc Eljárások szimmetrikus dimetilarginin kimutatására
EP2349335B1 (en) 2008-10-24 2013-08-07 ARK Diagnostics, Inc. Levetiracetam immunoassays
CA2763948C (en) * 2009-06-02 2019-03-12 Biocrates Life Sciences Ag Combination of amino acids, acylcarnitines and biogenic amines for the assessment of chronic kidney disease
CN101587118B (zh) 2009-07-03 2012-09-12 长春迪瑞医疗科技股份有限公司 肌酐尿液分析试纸及制备方法
CN101598727B (zh) 2009-07-09 2012-10-10 上海科华生物工程股份有限公司 定量测定人体血液尿素含量的干化学试纸
CN101865911A (zh) 2010-03-16 2010-10-20 苏州市玮琪生物科技有限公司 一种尿肌酐定量检测卡
US8329424B2 (en) * 2010-06-25 2012-12-11 Siemens Healthcare Diagnostics Reduction in false results in assay measurements
EP2612147B1 (de) 2010-11-17 2016-03-30 Karl-Heinz Kellner Automatenfähiger immunoassay für biogene amine
JP2012112785A (ja) 2010-11-24 2012-06-14 Tohoku Univ 透析膜の評価方法
CN102154444B (zh) * 2010-12-30 2013-09-25 北京九强生物技术股份有限公司 测定不对称二甲基精氨酸浓度的方法及诊断试剂盒
US8394647B2 (en) 2011-02-17 2013-03-12 Siemens Healthcare Diagnostics Inc. Reducing non-covalently bound polysaccharide on supports
CN102628868B (zh) 2011-12-30 2014-09-17 北京九强生物技术股份有限公司 检测非对称二甲基精氨酸含量的胶乳增强免疫比浊法试剂盒
JP6373191B2 (ja) 2012-01-10 2018-08-15 アイデックス ラボラトリーズ インコーポレイテッドIDEXX Laboratories, Inc. 免疫学的検定用試験スライド
WO2013124478A1 (en) * 2012-02-24 2013-08-29 Universität des Saarlandes Symmetric dimethylarginine (sdma) modifies high density lipoprotein (hdl) to induce endothelial dysfunction
US9074482B2 (en) * 2012-04-24 2015-07-07 United Technologies Corporation Airfoil support method and apparatus
US20140038203A1 (en) 2012-07-09 2014-02-06 Musc Foundation For Research Development Methods for detecting or predicting kidney disease
PT2888257T (pt) * 2012-08-21 2017-11-14 Janssen Pharmaceutica Nv Haptenos de quetiapina para utilização em ensaios imunológicos
WO2014113717A1 (en) 2013-01-18 2014-07-24 Ark Diagnostics, Inc. Voriconazole immunoassays
EP2956444B1 (en) 2013-02-13 2018-05-30 ARK Diagnostics, Inc. Posaconazole immunoassays
AU2014315063B2 (en) 2013-09-05 2020-07-23 Idexx Laboratories, Inc. Methods for detecting renal disease
EP3083657B1 (en) 2013-12-17 2022-01-26 Siemens Healthcare Diagnostics Inc. Preparation of multi-hapten mutant g6pdh conjugates and their use for detection of multiple analytes
AU2016219847B2 (en) * 2015-02-20 2022-03-10 Idexx Laboratories, Inc. Homogenous immunoassay with compensation for background signal
CN105753969A (zh) * 2016-04-06 2016-07-13 苏州博源医疗科技有限公司 非对称二甲基精氨酸免疫原、抗体和检测试剂及制备方法
EP3697499A4 (en) * 2017-10-19 2021-07-21 IDEXX Laboratories, Inc. DETECTION OF SYMMETRICAL DIMETHYLARGININE
US10745492B1 (en) * 2019-04-03 2020-08-18 Ark Diagnostics, Inc. Antibodies to symmetrically dimethylated arginine analytes and use thereof
US20230243852A1 (en) * 2022-01-26 2023-08-03 Idexx Laboratories, Inc. Methods and compositions for differentiating progressive chronic kidney disease from stable chronic kidney disease

Also Published As

Publication number Publication date
JP2018507408A (ja) 2018-03-15
US10775365B2 (en) 2020-09-15
KR102728614B1 (ko) 2024-11-08
CA3255043A1 (en) 2025-04-02
AR103745A1 (es) 2017-05-31
US20160245801A1 (en) 2016-08-25
BR112017017719A2 (pt) 2018-04-10
FI3259593T3 (fi) 2023-01-13
AU2022204015A1 (en) 2022-06-30
US20210018496A1 (en) 2021-01-21
KR20230018536A (ko) 2023-02-07
CN107250795B (zh) 2021-07-30
TW201643428A (zh) 2016-12-16
AU2022204015B2 (en) 2025-12-04
HUE060884T2 (hu) 2023-04-28
EP3259593B1 (en) 2022-10-05
EP4170346A1 (en) 2023-04-26
ES2936294T3 (es) 2023-03-15
CN107250795A (zh) 2017-10-13
US11913942B2 (en) 2024-02-27
US20240248081A1 (en) 2024-07-25
KR20170117574A (ko) 2017-10-23
KR102492243B1 (ko) 2023-01-25
AU2016219847A1 (en) 2017-08-24
EP3259593A1 (en) 2017-12-27
ZA201705365B (en) 2024-08-28
EP3259593A4 (en) 2018-08-08
CN113699125A (zh) 2021-11-26
NZ734445A (en) 2024-12-20
JP2021156896A (ja) 2021-10-07
JP7459018B2 (ja) 2024-04-01
CA2977062A1 (en) 2016-08-25
PL3259593T3 (pl) 2023-02-20
TWI721966B (zh) 2021-03-21
JP6896637B2 (ja) 2021-06-30
WO2016134251A1 (en) 2016-08-25
AU2016219847B2 (en) 2022-03-10

Similar Documents

Publication Publication Date Title
MX2020002799A (es) Dispositivo de ensayo biologico multiplexado con lectura electronica.
CO2019008675A2 (es) Anticuerpos anti-lag3 radiomarcados para la obtención de imágenes mediante inmuno-pet
MX2018015704A (es) Control de fluidos.
EA201992748A1 (ru) Диагностические анализы для обнаружения, количественного определения и/или отслеживания микроорганизмов и других аналитов
MX374652B (es) Ensayos para detectar la presencia o la cantidad de un anticuerpo antifármaco.
BR112016019836A2 (pt) método para analisar uma amostra de um sujeito, dispositivo de diagnóstico para utilização no diagnóstico da endometriose, kit, uso de um biomarcador, e, método para aumentar uma resposta de anticorpos em um sujeito
CR20180225A (es) Anticuerpo anti-tigit y métodos de uso
MX2017015011A (es) Ensayo a base de celulas para detectar homodimeros anti-cd3.
AR114789A1 (es) Anticuerpos anti-hla-g y uso de los mismos
MX2017010505A (es) Inmunoensayo homogeneo con compensacion para señal de fondo.
MX373248B (es) Prediccion de riesgo de evento cardiovascular y usos del mismo.
MX387936B (es) Metodo para la cuantificacion de huevos de parasitos en las heces.
MX2017010836A (es) Panel biomarcador para la deteccion de cancer.
MX2016005834A (es) Ensayos para igfbp7 con mejor rendimiento en muestras biológicas.
MX383381B (es) Métodos y composiciones para detectar proteínas mal plegadas.
CL2017002101A1 (es) Dispositivo, plataforma y ensayo para evaluación de células
MX2020003523A (es) Deteccion de dimetilarginina simetrica.
EA201991506A1 (ru) Системы и способы для тестирования и скрининга с использованием связанных с соединениями субстратов
BR112019006862A2 (pt) dispositivo de análise e método para testagem de uma amostra
EP3791483A4 (en) WEAK USER DETECTION IN A BEAM SELECTION FOR A MASSIVE MIMO RECEIVER
EP3992123A4 (en) SAMPLING DEVICE
MX382809B (es) Uso de tm9sf4 como un biomarcador para exosomas asociadas con tumores.
MX2019000591A (es) Tira mejorada de ensayo de analisis de orina de bajo volumen de muestra, kits analiticos y metodos de uso relacionados con la misma.
MX2018015047A (es) Metodo para la deteccion de un anticuerpo igm especifico para un flavivirus en una muestra.
WO2014151290A3 (en) Assay for predictive biomarkers