[go: up one dir, main page]

MX2017010569A - Dispositivo, plataforma y ensayo para evaluacion de celulas. - Google Patents

Dispositivo, plataforma y ensayo para evaluacion de celulas.

Info

Publication number
MX2017010569A
MX2017010569A MX2017010569A MX2017010569A MX2017010569A MX 2017010569 A MX2017010569 A MX 2017010569A MX 2017010569 A MX2017010569 A MX 2017010569A MX 2017010569 A MX2017010569 A MX 2017010569A MX 2017010569 A MX2017010569 A MX 2017010569A
Authority
MX
Mexico
Prior art keywords
response
provides
migration
cells
assay
Prior art date
Application number
MX2017010569A
Other languages
English (en)
Inventor
Pablo Acevedo Cox Juan
Original Assignee
Cells For Cells S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cells For Cells S A filed Critical Cells For Cells S A
Publication of MX2017010569A publication Critical patent/MX2017010569A/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5029—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell motility
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0694—Creating chemical gradients in a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dispersion Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Esta invención proporciona dispositivos capaces de evaluar la respuesta de migración en la presencia de un gradiente estable encapsulado de un factor o combinación de factores, y cuantificar la respuesta de adherencia dentro de los microcanales, en la presencia de diferentes factores. Esta invención también proporciona una plataforma para obtener información relacionada con la puntuación de migración o la cuantificación de las células adheridas a través del uso de los dispositivos de la presente invención, y permite que esta información sea utilizada para evaluar el potencial terapéutico. Adicionalmente, la invención brinda un método para cuantificar la respuesta de migración de las células y la respuesta de adherencia celular.
MX2017010569A 2015-02-20 2016-02-22 Dispositivo, plataforma y ensayo para evaluacion de celulas. MX2017010569A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB2015/051317 WO2016132182A1 (en) 2015-02-20 2015-02-20 Devices for studying chemotaxis/adherence in cells wherein gradients and channels are formed using hydrogels
PCT/IB2016/000274 WO2016132221A2 (en) 2015-02-20 2016-02-22 Device, platform, and assay for assessing cells

Publications (1)

Publication Number Publication Date
MX2017010569A true MX2017010569A (es) 2018-07-06

Family

ID=52684599

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017010569A MX2017010569A (es) 2015-02-20 2016-02-22 Dispositivo, plataforma y ensayo para evaluacion de celulas.

Country Status (7)

Country Link
US (1) US10766029B2 (es)
EP (1) EP3259066A4 (es)
JP (1) JP2018505691A (es)
CL (1) CL2017002101A1 (es)
MX (1) MX2017010569A (es)
PE (1) PE20180045A1 (es)
WO (2) WO2016132182A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018063914A1 (en) * 2016-09-29 2018-04-05 Animantis, Llc Methods and apparatus for assessing immune system activity and therapeutic efficacy
CN108619575A (zh) * 2018-06-15 2018-10-09 天津工业大学 一种可缓释生长因子的表层分子印迹高强度水凝胶膜的制备方法
CN109358009B (zh) * 2018-10-26 2021-08-10 武汉百德瑞康生物技术有限公司 胱抑素c测定试剂盒及其制备方法和检测方法
CN111695389B (zh) * 2019-03-15 2023-06-20 北京四维图新科技股份有限公司 一种车道线聚类方法及装置
AU2020395428A1 (en) * 2019-12-02 2022-06-02 Shen Zhen Biorocks Biotechnology Company Limited A chemical delivery system, device and method thereof
CN111138723B (zh) * 2019-12-10 2021-07-20 四川农业大学 一种3d打印梯度抗菌膜的制备方法、产品及其应用
CO2020015994A1 (es) 2020-12-18 2022-06-21 Inst Distrital De Ciencia Biotecnologia E Innovacion En Salud Idcbis Método in vitro para evaluación funcional de progenitores hematopoyéticos
CN112903637B (zh) * 2021-01-18 2022-06-03 江西英大生物技术有限公司 尿胰蛋白酶原-2的检测试剂盒、适配的检测装置及检测方法
CN114836291B (zh) * 2021-02-01 2025-11-21 深圳拜尔洛克生物技术有限公司 生物材料解冻复苏的系统及其方法
CN215775135U (zh) * 2021-03-03 2022-02-11 深圳拜尔洛克生物技术有限公司 用于生物组织冷冻保存或解冻复苏的芯片
CN113373198A (zh) * 2021-06-17 2021-09-10 上海睿钰生物科技有限公司 一种确定细胞的迁移能力的方法和系统
JP7685680B2 (ja) * 2022-01-28 2025-05-29 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド 細胞遊走、走化性、および機能に関するハイスループットアッセイ

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637469A (en) 1992-05-01 1997-06-10 Trustees Of The University Of Pennsylvania Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
US6699665B1 (en) * 2000-11-08 2004-03-02 Surface Logix, Inc. Multiple array system for integrating bioarrays
JP2005523710A (ja) * 2002-04-24 2005-08-11 サーフェイス ロジックス，インコーポレイティド 白血球遊走のモニター装置及び方法
US7857849B2 (en) * 2004-10-05 2010-12-28 The Board Of Trustees Of The Leland Stanford Junior Iniversity Artificial corneal implant
US20090136982A1 (en) 2005-01-18 2009-05-28 Biocept, Inc. Cell separation using microchannel having patterned posts
EP1846567A4 (en) 2005-01-20 2009-12-09 Univ California CELLULAR MICROARRAYS FOR SCREENING DIFFERENTIAL FACTORS
WO2009102453A2 (en) 2008-02-11 2009-08-20 The General Hospital Corporation System and method for quantitative assessment of biological migration behavior
JP5602718B2 (ja) * 2008-04-08 2014-10-08 マサチューセッツ インスティテュート オブ テクノロジー 三次元マイクロ流体プラットホームおよびその使用方法
JP5228826B2 (ja) * 2008-11-17 2013-07-03 大日本印刷株式会社 細胞画像解析装置および細胞画像解析方法
WO2010108095A2 (en) * 2009-03-19 2010-09-23 The General Hospital Corporation Microfluidic cell motility assay
US9261496B2 (en) * 2010-09-29 2016-02-16 Massachusetts Institute Of Technology Device for high throughput investigations of multi-cellular interactions
CN108424834A (zh) * 2011-05-27 2018-08-21 不列颠哥伦比亚大学 用于高通量分析的微流控细胞捕获和分析设备
KR101311325B1 (ko) 2012-09-13 2013-09-30 이상재 합성 디자인된 3차원 미세환경 구조물

Also Published As

Publication number Publication date
EP3259066A4 (en) 2018-12-05
WO2016132182A1 (en) 2016-08-25
US20180236442A1 (en) 2018-08-23
CL2017002101A1 (es) 2018-03-23
EP3259066A2 (en) 2017-12-27
JP2018505691A (ja) 2018-03-01
PE20180045A1 (es) 2018-01-15
US10766029B2 (en) 2020-09-08
WO2016132221A2 (en) 2016-08-25
WO2016132221A3 (en) 2016-10-13

Similar Documents

Publication Publication Date Title
MX2017010569A (es) Dispositivo, plataforma y ensayo para evaluacion de celulas.
AR102615A1 (es) Analizador de analitos
EP3444866A4 (en) SEPARATOR AND ELECTROCHEMICAL DEVICE THEREWITH
BR112017010190A2 (pt) sistema para medição de características, método de medição
WO2014201516A3 (en) Biomarker identification
AR105618A1 (es) Metilación del promotor del ligando al receptor de muerte programada (pd-l1) en cáncer
BR112014026440A2 (pt) assays, methods and apparatus for assessing rna disruption
WO2015185672A3 (en) New markers for the assessment of an increased risk for mortality
EP2937421A3 (en) Biomarker for predicting effect of an anti-C-met antibody
BR112016028838A2 (pt) anticorpos, ácido nucleico, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, métodos de detecção de lgr5 humano em uma amostra biológica, de detecção de um câncer, de identificação de um paciente com câncer, de seleção de um paciente com câncer para tratamento com um imunoconjugado e de tratamento de um paciente com câncer
EP3514880A4 (en) ELECTROLYTE AND ELECTROCHEMICAL DEVICE
EP3172570A4 (en) Analyte test strip assays, and test strips and kits for use in practicing the same
SG11201700424XA (en) Detection method using recombinant living cells for detecting xenobiotic substances and arrangement and test kit for performing the detection method
MX2017004816A (es) Métodos para predecir resultados clínicos en sujetos afectados con colitis ulcerosa.
ZA201808289B (en) Assay device and method for assessing blood cells
UA96501U (uk) Спосіб прогнозування зрощення перелому
UA95606U (uk) Спосіб прогнозування зрощення перелому
UA97451U (en) Method for predicting flow of pulmonary sarcoidosis
UA95641U (uk) Спосіб прогнозування зрощення перелому
UA95640U (uk) Спосіб прогнозування зрощення перелому
UA95627U (uk) Спосіб прогнозування зрощення перелому
UA95625U (uk) Спосіб прогнозування зрощення перелому
UA95657U (uk) Спосіб прогнозування зрощення перелому
UA95623U (uk) Спосіб прогнозування зрощення перелому
UA95580U (uk) Спосіб прогнозування зрощення перелому