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MX2017009193A - Lente de contacto iontoforetica. - Google Patents

Lente de contacto iontoforetica.

Info

Publication number
MX2017009193A
MX2017009193A MX2017009193A MX2017009193A MX2017009193A MX 2017009193 A MX2017009193 A MX 2017009193A MX 2017009193 A MX2017009193 A MX 2017009193A MX 2017009193 A MX2017009193 A MX 2017009193A MX 2017009193 A MX2017009193 A MX 2017009193A
Authority
MX
Mexico
Prior art keywords
charged
therapeutic composition
charged therapeutic
current source
compound
Prior art date
Application number
MX2017009193A
Other languages
English (en)
Inventor
Manzo Michael
Original Assignee
Eyegate Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eyegate Pharmaceuticals Inc filed Critical Eyegate Pharmaceuticals Inc
Publication of MX2017009193A publication Critical patent/MX2017009193A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04—Contact lenses for the eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Neurology (AREA)

Abstract

Se proveen lentes de contacto para terapia iontoforética ocular, cuyas implementaciones incluyen un depósito adaptado para contener un compuesto terapéutico cargado, una fuente de corriente que provee corriente iontoforética a la composición terapéutica cargada que afecta el suministro de la composición terapéutica cargada en un globo ocular, y un circuito de detección que controla la fuente de corriente para mantener una escala de pH seleccionada de la composición terapéutica cargada; modalidades alternativas incluyen electrodos de sacrificio activos para generar iones suficientes para proveer una fuerza repulsiva electromotriz al compuesto cargado para efectuar el transporte en el tejido ocular.
MX2017009193A 2015-01-22 2016-01-22 Lente de contacto iontoforetica. MX2017009193A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562106578P 2015-01-22 2015-01-22
PCT/US2016/014636 WO2016118933A1 (en) 2015-01-22 2016-01-22 Iontophoretic contact lens

Publications (1)

Publication Number Publication Date
MX2017009193A true MX2017009193A (es) 2017-12-12

Family

ID=56417852

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017009193A MX2017009193A (es) 2015-01-22 2016-01-22 Lente de contacto iontoforetica.

Country Status (9)

Country Link
US (1) US9937074B2 (es)
EP (1) EP3247452A4 (es)
JP (1) JP2018502639A (es)
CN (1) CN106999711A (es)
AU (1) AU2016209028A1 (es)
BR (1) BR112017009054A2 (es)
CA (1) CA2973595A1 (es)
MX (1) MX2017009193A (es)
WO (1) WO2016118933A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2019121873A (ru) 2016-12-13 2021-01-15 БЕТА ТЕРАПЬЮТИКС ПиТиУай ЛТД Ингибиторы гепараназы и их применение
US11787783B2 (en) 2016-12-13 2023-10-17 Beta Therapeutics Pty Ltd Heparanase inhibitors and use thereof
DE102017213056A1 (de) 2017-07-28 2019-01-31 Continental Teves Ag & Co. Ohg Verfahren zum Unterdrücken von Bremsgeräuschen, zentraler Server, Fahrzeugsteuerungsmodul und Speichermedium
US11998481B2 (en) * 2018-08-02 2024-06-04 University Of Florida Research Foundation Inc. Methods and compositions for iontophoretic drug delivery to the eye
WO2020072513A1 (en) * 2018-10-02 2020-04-09 Tufts Medical Center, Inc. Systems and methods for sensing and correcting electrical activity of nerve tissue
KR102137437B1 (ko) 2018-11-06 2020-07-24 한국과학기술연구원 비침습적 약물 전달용 스마트 콘택트렌즈
JP7531496B2 (ja) 2019-01-09 2024-08-09 トゥウェンティ トゥウェンティ セラピューティクス エルエルシー 眼球装着装置からのプログラム可能な治療剤送達
BR112021013455A2 (pt) * 2019-01-09 2021-09-14 Twenty Twenty Therapeutics Llc Dispositivo de dispensação de agente terapêutico, e, sistema
JP7352979B2 (ja) * 2019-03-04 2023-09-29 国立大学法人東北大学 眼用医療機器の水分の吸収又は排出方法及び眼用医療機器
US20220183880A1 (en) * 2019-04-02 2022-06-16 The Regents Of The University Of California Method and apparatus to modify the cornea using electrochemistry
CN110367927B (zh) * 2019-08-01 2022-04-08 中山大学 青光眼眼压连续检测系统及其检测方法
US20230271002A1 (en) * 2020-07-31 2023-08-31 Board Of Regents Of The University Of Nebraska Hydrogel ionic circuit based devices for electrical stimulation and drug therapy
CN114355628A (zh) * 2020-09-29 2022-04-15 鼎硕光学股份有限公司 光学装置及其制造方法
CN113413541A (zh) * 2021-06-17 2021-09-21 中央民族大学 一种利用环状电极的眼部离子电渗透药物输送设备及方法
WO2023076141A1 (en) * 2021-10-28 2023-05-04 Twenty Twenty Therapeutics Llc Controlled release of a therapeutic from an ophthalmic device with a locally enhanced concentration of chloride ions
WO2025096506A1 (en) * 2023-11-03 2025-05-08 Verily Life Sciences Llc Ophthalmic device with a shielding material to protect against degradation during active drug release

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4915685A (en) 1986-03-19 1990-04-10 Petelenz Tomasz J Methods and apparatus for iontophoresis application of medicaments at a controlled ph through ion exchange
US6544193B2 (en) 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
FR2773320B1 (fr) * 1998-01-05 2000-03-03 Optisinvest Dispositif pour le transfert intraoculaire de produits actifs par iontophorese
US7346389B1 (en) 1998-09-24 2008-03-18 Newsome David A Dilation enhancer with pre-medicated contact lenses
ATE290902T1 (de) * 1999-04-16 2005-04-15 Johnson & Johnson Consumer Vorrichtung zur iontophoretischen verabreichung von medikamenten mit internen sensoren
US6539251B2 (en) 1999-05-25 2003-03-25 Iomed, Inc. Ocular iontophoretic apparatus
US6319240B1 (en) 1999-05-25 2001-11-20 Iomed, Inc. Methods and apparatus for ocular iontophoresis
US6579276B2 (en) 2001-01-22 2003-06-17 Iomed, Inc. Ocular iontophoretic device and method for inhibiting vascular endothelial growth factor (VEGF) using the same
US6697668B2 (en) 2001-01-25 2004-02-24 Iomed, Inc. Ocular iontophoretic device and method for using the same
US20020107508A1 (en) * 2001-02-05 2002-08-08 Burnett Daniel R. Incisionless corneal sculpting technique and devices
FR2830767B1 (fr) 2001-10-12 2004-03-12 Optis France Sa Dispositif de delivrance de medicaments par iontophorese ou electroporation introculaire
FR2830766B1 (fr) 2001-10-12 2004-03-12 Optis France Sa Dispositif de delivrance de medicaments par iontophorese transpalpebrale
PL205827B1 (pl) 2001-10-31 2010-05-31 Tti Ellebeau Urządzenie do jontoforezy
IL147921A0 (en) 2002-01-31 2002-08-14 Abdulrazik Mohammad A method for treating central nervous system disorders by ocular dosing
US6801804B2 (en) 2002-05-03 2004-10-05 Aciont, Inc. Device and method for monitoring and controlling electrical resistance at a tissue site undergoing iontophoresis
BRPI0509334A (pt) 2004-04-30 2007-10-16 Eyegate Pharma S A dispositivo de iontoforese ocular, que diminui as irritações
FR2869531B1 (fr) 2004-04-30 2006-07-14 Optis France Sa Sa Dispositif de iontophorese oculaire diminuant les irritations
US8246949B2 (en) * 2004-10-27 2012-08-21 Aciont, Inc. Methods and devices for sustained in-vivo release of an active agent
WO2006072887A1 (en) 2005-01-05 2006-07-13 Eyegate Pharma Sa Ocular iontophoresis device for delivering sirna and aptamers
WO2007125383A2 (en) 2005-08-05 2007-11-08 Universite De Geneve Topical drug delivery by iontophoresis
US8755880B2 (en) 2005-10-24 2014-06-17 Aciont, Inc. Intraocular iontophoretic device and associated methods
US20070260171A1 (en) * 2005-09-27 2007-11-08 Higuchi John W Intraocular iontophoretic device and associated methods
WO2007038555A1 (en) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. Iontophoretic device and method of delivery of active agents to biological interface
US20070074590A1 (en) 2005-09-30 2007-04-05 Transcutaneous Technologies Inc. Method and system to detect malfunctions in an iontophoresis device that delivers active agents to biological interfaces
US8634907B2 (en) * 2005-10-24 2014-01-21 Aciont, Inc. Intraocular iontophoretic device and associated methods
US8099162B2 (en) 2005-11-29 2012-01-17 Eyegate Pharma, S.A.S. Ocular iontophoresis device
US20070299386A1 (en) 2006-06-23 2007-12-27 Minu, L.L.C. Delivery of an ocular agent using iontophoresis
US20080027371A1 (en) 2006-07-26 2008-01-31 Higuchi John W Method and device for minimally invasive site specific ocular drug delivery
JP2010511692A (ja) 2006-12-05 2010-04-15 アイゲート ファーマ エスエーエス イオントフォレシスを通じての核酸の強化された網膜送達
KR101604238B1 (ko) 2007-09-28 2016-03-17 존슨 앤드 존슨 컨수머 캄파니즈, 인코포레이티드 전기 발생 미립자 및 이의 용도
US8480638B2 (en) * 2007-10-04 2013-07-09 Aciont, Inc. Intraocular iontophoretic device and associated methods
JP2011512903A (ja) 2008-02-25 2011-04-28 アイゲート ファーマ エスエーエス イオントフォレシスを介した眼組織への治療薬の向上した送達
US20100040669A1 (en) 2008-08-12 2010-02-18 Higuchi John W Non-Invasive Ocular Delivery of Rapamycin
EP2370155B1 (en) * 2008-12-31 2018-07-04 Eyegate Pharmaceuticals, Inc. System for ocular iontophoresis with buffering
KR101669715B1 (ko) 2011-01-12 2016-10-27 수프트 이탈리아 에스피에이 원추각막 치료용 이온이동법에 의한 리보플라빈의 각막 전달 장치 및 방법
WO2012162459A1 (en) * 2011-05-26 2012-11-29 Pepose Jay Device and method for administering eye medications
US8857983B2 (en) 2012-01-26 2014-10-14 Johnson & Johnson Vision Care, Inc. Ophthalmic lens assembly having an integrated antenna structure
US20140107025A1 (en) 2012-04-16 2014-04-17 Jade Therapeutics, Llc Ocular drug delivery system
RU2627639C2 (ru) * 2012-06-29 2017-08-09 Джонсон Энд Джонсон Вижн Кэа, Инк. Способ и офтальмологическое устройство гальванического лечения глаз
US20140190839A1 (en) 2012-08-06 2014-07-10 Google Inc. Contact lenses having two-electrode electrochemical sensors
US8971978B2 (en) 2012-08-21 2015-03-03 Google Inc. Contact lens with integrated pulse oximeter
US8960899B2 (en) 2012-09-26 2015-02-24 Google Inc. Assembling thin silicon chips on a contact lens
US20150305929A1 (en) 2012-11-07 2015-10-29 Emmetrope Ophthalmics Llc Magnetic contact lenses and methods of treatment and diagnosis using the same
CN203389001U (zh) 2013-05-30 2014-01-15 中山大学中山眼科中心 一种眼后段透巩膜控释给药装置
US9101309B1 (en) 2013-11-26 2015-08-11 Google Inc. Method and system for measuring retinal
US9289123B2 (en) 2013-12-16 2016-03-22 Verily Life Sciences Llc Contact lens for measuring intraocular pressure
US9761874B2 (en) 2013-12-30 2017-09-12 Verily Life Sciences Llc Fabrication methods for batteries
US9678361B2 (en) 2014-06-13 2017-06-13 Verily Life Sciences Llc Power delivery for accommodation by an eye-mountable device

Also Published As

Publication number Publication date
CA2973595A1 (en) 2016-07-28
EP3247452A4 (en) 2018-11-14
AU2016209028A1 (en) 2017-05-11
EP3247452A1 (en) 2017-11-29
CN106999711A (zh) 2017-08-01
US20160213514A1 (en) 2016-07-28
US9937074B2 (en) 2018-04-10
WO2016118933A1 (en) 2016-07-28
BR112017009054A2 (pt) 2018-01-30
JP2018502639A (ja) 2018-02-01

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