MX2017008751A - CHEMICAL PROTEIN FOR THE PREVENTION AND DIAGNOSIS OF RESPIRATORY AND REPRODUCTIVE SYNDROME PORCIONO (PRSS). - Google Patents
CHEMICAL PROTEIN FOR THE PREVENTION AND DIAGNOSIS OF RESPIRATORY AND REPRODUCTIVE SYNDROME PORCIONO (PRSS).Info
- Publication number
- MX2017008751A MX2017008751A MX2017008751A MX2017008751A MX2017008751A MX 2017008751 A MX2017008751 A MX 2017008751A MX 2017008751 A MX2017008751 A MX 2017008751A MX 2017008751 A MX2017008751 A MX 2017008751A MX 2017008751 A MX2017008751 A MX 2017008751A
- Authority
- MX
- Mexico
- Prior art keywords
- protein
- respiratory
- porciono
- prss
- diagnosis
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 102100038395 Granzyme K Human genes 0.000 title 1
- 101001033007 Homo sapiens Granzyme K Proteins 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 230000001850 reproductive effect Effects 0.000 title 1
- 230000000241 respiratory effect Effects 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
- 241001135989 Porcine reproductive and respiratory syndrome virus Species 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 101710172711 Structural protein Proteins 0.000 abstract 1
- 241000282887 Suidae Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000005875 antibody response Effects 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 229940124452 immunizing agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
Abstract
La presente invención se refiere a una proteína quimérica conformada por secuencias cortas de algunas de algunas de las proteínas estructurales del virus del síndrome respiratorio y reproductivo porcino (PRRSV). La proteína es utilizada como antígeno de captura en un ensayo por inmunoadsorción ligado a enzimas para la detección de anticuerpos presentes en sueros de cerdos infectados con el virus. La proteína también es administrada en lechones e induce una respuesta rápida de anticuerpos, actuando como agente inmunizante para el control del PRRSV en etapas tempranas del crecimiento del cerdo.The present invention relates to a chimeric protein formed by short sequences of some of some of the structural proteins of the porcine respiratory and reproductive syndrome virus (PRRSV). The protein is used as a capture antigen in an enzyme-linked immunoadsorption assay for the detection of antibodies present in sera from pigs infected with the virus. The protein is also administered in piglets and induces a rapid antibody response, acting as an immunizing agent for the control of PRRSV in early stages of pig growth.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2017008751A MX386785B (en) | 2017-06-29 | 2017-06-29 | Chimeric protein for the prevention and diagnosis of porcine reproductive and respiratory syndrome (PRSS). |
| PCT/MX2018/000052 WO2019004811A1 (en) | 2017-06-29 | 2018-06-13 | Chimeric protein for the prevention and diagnosis of porcine respiratory and reproductive syndrome (prrs) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2017008751A MX386785B (en) | 2017-06-29 | 2017-06-29 | Chimeric protein for the prevention and diagnosis of porcine reproductive and respiratory syndrome (PRSS). |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017008751A true MX2017008751A (en) | 2019-02-08 |
| MX386785B MX386785B (en) | 2025-03-19 |
Family
ID=64742556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017008751A MX386785B (en) | 2017-06-29 | 2017-06-29 | Chimeric protein for the prevention and diagnosis of porcine reproductive and respiratory syndrome (PRSS). |
Country Status (2)
| Country | Link |
|---|---|
| MX (1) | MX386785B (en) |
| WO (1) | WO2019004811A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110894243B (en) * | 2019-12-16 | 2021-07-13 | 中国农业大学 | A porcine blue ear virus chimeric antigen and colloidal gold immunochromatographic test strip for detecting porcine blue ear virus antibody |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007064742A2 (en) * | 2005-11-29 | 2007-06-07 | Iowa State University Research Foundation, Inc. | Identification of protective antigenic determinants of porcine reproductive and respiratory syndrome virus (prrsv) and uses thereof |
| US7465455B2 (en) * | 2006-07-05 | 2008-12-16 | Healthbanks Biotech Co., Ltd. | Fusion protein of porcine reproductive and respiratory syndrome virus as PRRS vaccine |
| EP2457583A1 (en) * | 2010-11-26 | 2012-05-30 | Consejo Superior De Investigaciones Cientificas | Nucleic acids encoding PRRSV GP5-ecto and M protein |
| EP2804000A1 (en) * | 2013-05-15 | 2014-11-19 | Prionics AG | Method for the detection and classification of PRRSV-infections in swine herds and diagnostic antigen compositions for such methods |
| DK3302543T3 (en) * | 2015-06-01 | 2020-05-18 | Reber Genetics Co Ltd | VACCINE COMPOSITIONS AGAINST PORCINT REPRODUCTION AND RESPIRATION SYNDROME AND PORCINT CIRCOVIRUS-ASSOCIATED DISEASES |
| DK3313864T3 (en) * | 2015-06-23 | 2021-11-01 | Boehringer Ingelheim Animal Health Usa Inc | RECOMBINANT VIRUS VECTORS CONTAINING PRRSV MINOR PROTEIN AND METHODS OF MANUFACTURE AND USE |
-
2017
- 2017-06-29 MX MX2017008751A patent/MX386785B/en unknown
-
2018
- 2018-06-13 WO PCT/MX2018/000052 patent/WO2019004811A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| MX386785B (en) | 2025-03-19 |
| WO2019004811A1 (en) | 2019-01-03 |
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