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MX2017008748A - Ensayo para detectar dipeptidil peptidasa iv (dpp-4) humana. - Google Patents

Ensayo para detectar dipeptidil peptidasa iv (dpp-4) humana.

Info

Publication number
MX2017008748A
MX2017008748A MX2017008748A MX2017008748A MX2017008748A MX 2017008748 A MX2017008748 A MX 2017008748A MX 2017008748 A MX2017008748 A MX 2017008748A MX 2017008748 A MX2017008748 A MX 2017008748A MX 2017008748 A MX2017008748 A MX 2017008748A
Authority
MX
Mexico
Prior art keywords
assay
dpp
detect human
human dpp
antibodies
Prior art date
Application number
MX2017008748A
Other languages
English (en)
Inventor
Xiao Xiaodong
S Chowdhury Partha
Ying Chang Chien-
Original Assignee
Medimmune Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Llc filed Critical Medimmune Llc
Publication of MX2017008748A publication Critical patent/MX2017008748A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La presente invención se refiere a un ensayo sólido, sensible y específico para la detección y medición de los niveles de DPP-4 en muestras obtenidas de pacientes humanos. La descripción adicionalmente proporciona nuevos anticuerpos monoclonales anti-DPP-4 que reconocen la DPP-4 humana, y kits de ensayo que comprenden uno o más de estos anticuerpos.
MX2017008748A 2015-01-09 2016-01-08 Ensayo para detectar dipeptidil peptidasa iv (dpp-4) humana. MX2017008748A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562101697P 2015-01-09 2015-01-09
PCT/US2016/012603 WO2016112261A2 (en) 2015-01-09 2016-01-08 Assay to detect human dpp-4

Publications (1)

Publication Number Publication Date
MX2017008748A true MX2017008748A (es) 2017-11-17

Family

ID=56356576

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017008748A MX2017008748A (es) 2015-01-09 2016-01-08 Ensayo para detectar dipeptidil peptidasa iv (dpp-4) humana.

Country Status (14)

Country Link
US (2) US10351630B2 (es)
EP (1) EP3242686B1 (es)
JP (1) JP2018502577A (es)
KR (1) KR20170098941A (es)
CN (1) CN107206079A (es)
AU (1) AU2016205188A1 (es)
BR (1) BR112017011724A2 (es)
CA (1) CA2970540A1 (es)
HK (2) HK1244444A1 (es)
IL (1) IL252528A0 (es)
MX (1) MX2017008748A (es)
RU (1) RU2017127182A (es)
SG (1) SG11201705598VA (es)
WO (1) WO2016112261A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118359716A (zh) * 2023-01-18 2024-07-19 江苏众红生物工程创药研究院有限公司 抗cd26抗体及其用途
CN118791612A (zh) * 2023-04-14 2024-10-18 江苏众红生物工程创药研究院有限公司 靶向cd26的抗原结合蛋白及其药物应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681718A (en) 1986-03-14 1997-10-28 Celltech Limited Methods for enhanced production of tissue plasminogen activator in cell culture using alkanoic acids or salts thereof
US5892019A (en) 1987-07-15 1999-04-06 The United States Of America, As Represented By The Department Of Health And Human Services Production of a single-gene-encoded immunoglobulin
US7115555B2 (en) * 1998-07-09 2006-10-03 Baylor College Of Medicine Hypohidrotic ectodermal dysplasia genes and proteins
US6573096B1 (en) * 2000-04-01 2003-06-03 The Research Foundation At State University Of New York Compositions and methods for inhibition of cancer invasion and angiogenesis
KR100863624B1 (ko) * 2001-05-11 2008-10-15 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 Ｃｄ26을 발현하는 세포와 연관된 질환의 치료제로사용되는 항-ｃｄ26 단클론항체
GB0216648D0 (en) 2002-07-18 2002-08-28 Lonza Biologics Plc Method of expressing recombinant protein in CHO cells
WO2004104216A2 (en) 2003-05-21 2004-12-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with dipeptidylpeptidase iv (dpp4)
GB0407315D0 (en) 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
EP1725585A2 (en) 2004-03-10 2006-11-29 Lonza Ltd Method for producing antibodies
CN101282994B (zh) * 2005-07-22 2013-09-18 Y's治疗有限公司 抗cd26抗体及其使用方法
WO2008091814A2 (en) 2007-01-22 2008-07-31 Wyeth Assessment of asthma and allergen-dependent gene expression
NZ588853A (en) 2008-03-31 2013-07-26 Genentech Inc Compositions and methods for treating and diagnosing asthma
US20100221752A2 (en) 2008-10-06 2010-09-02 Somalogic, Inc. Ovarian Cancer Biomarkers and Uses Thereof
WO2012031122A2 (en) * 2010-09-03 2012-03-08 Immport Therapeutics, Inc. Methods and compositions for the diagnosis and treatment of cancer and autoimmune disorders
MX2013004212A (es) 2010-10-15 2013-09-02 Medimmune Ltd Terapias para mejorar la funcion pulmonar.
BR112013013460A8 (pt) 2010-12-16 2019-02-12 Genentech Inc métodos de identificação de um paciente com asma, método de monitoramento de um paciente com asma, uso de um kit de detecção de periostina total, kit de medição da periostina total, uso de um anticorpo anti-il-13, uso de uma quantidade terapeuticamente eficaz de lebrikizumab, uso de um inibidor da via de th2, método de avaliação de eventos adversos, anticorpo anti-periostina e teste de periostina total
US8961965B2 (en) 2011-05-18 2015-02-24 Medimmune, Llc Methods of diagnosing and treating pulmonary diseases or disorders
US20160363591A1 (en) 2014-01-27 2016-12-15 Medimmune, Llc Dipeptidyl peptidase-4 (dpp4/cd26) as a peripheral biomarker of il-13 activation in asthmatic lung

Also Published As

Publication number Publication date
BR112017011724A2 (pt) 2018-05-15
KR20170098941A (ko) 2017-08-30
WO2016112261A2 (en) 2016-07-14
HK1243953A1 (zh) 2018-07-27
WO2016112261A3 (en) 2016-09-01
CN107206079A (zh) 2017-09-26
US10351630B2 (en) 2019-07-16
EP3242686A4 (en) 2018-06-06
EP3242686A2 (en) 2017-11-15
SG11201705598VA (en) 2017-08-30
RU2017127182A (ru) 2019-02-11
AU2016205188A1 (en) 2017-06-22
HK1244444A1 (zh) 2018-08-10
CA2970540A1 (en) 2016-07-14
IL252528A0 (en) 2017-07-31
US20190352425A1 (en) 2019-11-21
JP2018502577A (ja) 2018-02-01
EP3242686B1 (en) 2020-07-08
US20160200832A1 (en) 2016-07-14

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