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MX2017005650A - Composicion de antigeno para detectar enfermedad de chagas. - Google Patents

Composicion de antigeno para detectar enfermedad de chagas.

Info

Publication number
MX2017005650A
MX2017005650A MX2017005650A MX2017005650A MX2017005650A MX 2017005650 A MX2017005650 A MX 2017005650A MX 2017005650 A MX2017005650 A MX 2017005650A MX 2017005650 A MX2017005650 A MX 2017005650A MX 2017005650 A MX2017005650 A MX 2017005650A
Authority
MX
Mexico
Prior art keywords
cruzi
composition
polypeptides
chagas disease
antigen composition
Prior art date
Application number
MX2017005650A
Other languages
English (en)
Other versions
MX377864B (es
Inventor
Scholz Christian
Roessler Dieter
Muench Peter
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2017005650A publication Critical patent/MX2017005650A/es
Publication of MX377864B publication Critical patent/MX377864B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905—Protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/005—Trypanosoma antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/26—Infectious diseases, e.g. generalised sepsis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a una composición de polipéptidos adecuados para detectar anticuerpos contra Trypanosoma cruzi (T. cruzi) en una muestra biológica aislada que consiste de tres polipéptidos 1F8, JL7 y Cruzipain. Es también parte de la invención un método de producción de una composición soluble e inmunorreactiva de los polipéptidos adecuados para detectar los anticuerpos contra T. cruzi, utilizando la composición de los polipéptidos. Además, la invención se refiere a los métodos para detectar anticuerpos específicos para T. cruzi en una muestra aislada, en donde una composición de los polipéptidos de T. cruzi es utilizada así como un kit de reactivos que comprende la composición de los polipéptidos de T. cruzi.
MX2017005650A 2014-11-06 2015-11-04 Composición de antígeno para detectar enfermedad de chagas. MX377864B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14192004.1A EP3018479A1 (en) 2014-11-06 2014-11-06 Antigen composition for detecting Chagas disease
PCT/EP2015/075691 WO2016071392A1 (en) 2014-11-06 2015-11-04 Antigen composition for detecting chagas disease

Publications (2)

Publication Number Publication Date
MX2017005650A true MX2017005650A (es) 2017-06-29
MX377864B MX377864B (es) 2025-03-10

Family

ID=51932184

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017005650A MX377864B (es) 2014-11-06 2015-11-04 Composición de antígeno para detectar enfermedad de chagas.

Country Status (7)

Country Link
US (1) US10094828B2 (es)
EP (2) EP3018479A1 (es)
JP (1) JP6763855B2 (es)
CN (1) CN107003309B (es)
ES (1) ES2705429T3 (es)
MX (1) MX377864B (es)
WO (1) WO2016071392A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3018479A1 (en) * 2014-11-06 2016-05-11 Roche Diagniostics GmbH Antigen composition for detecting Chagas disease
JP7606210B2 (ja) * 2019-02-08 2024-12-26 国立大学法人東京科学大学 ホモジニアス免疫測定法に適した酵素変異体
CN111751416A (zh) * 2020-07-03 2020-10-09 福建中医药大学 一种新型的美洲大蠊多肽快速检测方法
WO2024229330A1 (en) * 2023-05-03 2024-11-07 Vida Pharmacal Inc. Modified chimeric antigens ibmp 8.1 and 8.3 for the detection and diagnosis of trypanosoma cruzi

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0976763B1 (en) * 1998-07-30 2003-11-05 Innogenetics N.V. Antigens and immunoassays for diagnosing Chagas' disease
PE20050942A1 (es) 2003-12-04 2005-11-10 Louis V Kirchhoff Polipeptidos recombinantes para diagnosticar la infeccion con el trypanosoma cruzi
CA2700000A1 (en) 2007-07-30 2009-02-05 Rick L. Tarleton Diagnostic assay for trypanosoma cruzi infection
WO2010142829A1 (es) * 2009-06-12 2010-12-16 Consejo Superior De Investigaciones Científicas (Csic) Método de obtención de datos útiles para el diagnóstico diferencial de la enfermedad de chagas, y para evaluar la respuesta al tratamiento
EP3018479A1 (en) * 2014-11-06 2016-05-11 Roche Diagniostics GmbH Antigen composition for detecting Chagas disease

Also Published As

Publication number Publication date
EP3215848A1 (en) 2017-09-13
US20170248597A1 (en) 2017-08-31
JP6763855B2 (ja) 2020-09-30
WO2016071392A1 (en) 2016-05-12
CN107003309A (zh) 2017-08-01
MX377864B (es) 2025-03-10
EP3215848B1 (en) 2018-10-10
BR112017006569A2 (pt) 2018-01-16
EP3018479A1 (en) 2016-05-11
US10094828B2 (en) 2018-10-09
JP2017534055A (ja) 2017-11-16
CN107003309B (zh) 2020-05-19
ES2705429T3 (es) 2019-03-25

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