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MX2017005348A - Aislamiento continuo integrado de flujos de fluido procedentes de recipientes de procesos esteriles. - Google Patents

Aislamiento continuo integrado de flujos de fluido procedentes de recipientes de procesos esteriles.

Info

Publication number
MX2017005348A
MX2017005348A MX2017005348A MX2017005348A MX2017005348A MX 2017005348 A MX2017005348 A MX 2017005348A MX 2017005348 A MX2017005348 A MX 2017005348A MX 2017005348 A MX2017005348 A MX 2017005348A MX 2017005348 A MX2017005348 A MX 2017005348A
Authority
MX
Mexico
Prior art keywords
fluid flows
sterile process
integrated continuous
continuous insulation
process containers
Prior art date
Application number
MX2017005348A
Other languages
English (en)
Inventor
Snow Robert
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of MX2017005348A publication Critical patent/MX2017005348A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/26—Conditioning fluids entering or exiting the reaction vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/12—Apparatus for enzymology or microbiology with sterilisation, filtration or dialysis means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/26—Inoculator or sampler
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02—Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/06—Means for testing the completeness of the sterilization
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

En la presente descripción se proporcionan procesos de aislamiento y el hardware asociado para permitir que sean aislados los flujos de fluidos de un sistema esterilizado (p. ej., un recipiente de proceso estéril) que contiene un proceso estéril. Los procesos de aislamiento descritos en el presente documento permiten la eliminación continua de flujos de fluido (p. ej., flujos de desechos, líquido que contiene proteínas terapéuticas recombinantes) desde un sistema esterilizado (p. ej., un sistema de fabricación biológica), lo que prevé menos manipulación manual del sistema esterilizado y una disminución del riesgo de contaminación del sistema esterilizado.
MX2017005348A 2014-10-24 2015-10-20 Aislamiento continuo integrado de flujos de fluido procedentes de recipientes de procesos esteriles. MX2017005348A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462068181P 2014-10-24 2014-10-24
PCT/US2015/056422 WO2016064846A1 (en) 2014-10-24 2015-10-20 Integrated continuous isolation of fluid streams from sterile process vessels

Publications (1)

Publication Number Publication Date
MX2017005348A true MX2017005348A (es) 2017-07-28

Family

ID=54478962

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017005348A MX2017005348A (es) 2014-10-24 2015-10-20 Aislamiento continuo integrado de flujos de fluido procedentes de recipientes de procesos esteriles.

Country Status (17)

Country Link
US (3) US20160115438A1 (es)
EP (1) EP3209765B1 (es)
JP (2) JP6672287B2 (es)
KR (1) KR102465762B1 (es)
CN (2) CN107109322B (es)
AU (1) AU2015336130B2 (es)
BR (1) BR112017008252B1 (es)
CA (1) CA2965478C (es)
DK (1) DK3209765T3 (es)
ES (1) ES2931455T3 (es)
HU (1) HUE060385T2 (es)
IL (1) IL251819B (es)
MX (1) MX2017005348A (es)
RU (1) RU2713126C2 (es)
SG (2) SG11201703265XA (es)
TW (2) TWI740417B (es)
WO (1) WO2016064846A1 (es)

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JP7325884B2 (ja) 2017-10-31 2023-08-15 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー 可撓性バッグ
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CN114947113A (zh) * 2021-02-24 2022-08-30 游家源 植物性胺基酸酵素制造方法及其设备
EP4339274B1 (en) * 2022-09-13 2025-03-26 Sartorius Stedim Biotech GmbH Method for operating a bioprocess installation for production of a bioproduct
JP7422925B1 (ja) 2023-07-19 2024-01-26 佐竹マルチミクス株式会社 バイオリアクター培養方法、及び、バイオリアクターの滅菌装置

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Also Published As

Publication number Publication date
TWI691342B (zh) 2020-04-21
RU2017115655A (ru) 2018-11-26
CN107109322A (zh) 2017-08-29
CN113105992B (zh) 2024-05-14
CA2965478C (en) 2023-03-14
RU2020102925A3 (es) 2022-02-16
EP3209765A1 (en) 2017-08-30
RU2017115655A3 (es) 2019-08-07
EP3209765B1 (en) 2022-09-07
RU2020102925A (ru) 2021-07-26
US20220081669A1 (en) 2022-03-17
RU2713126C2 (ru) 2020-02-03
TW201625318A (zh) 2016-07-16
SG11201703265XA (en) 2017-05-30
CA2965478A1 (en) 2016-04-28
KR20170072932A (ko) 2017-06-27
US11920120B2 (en) 2024-03-05
WO2016064846A1 (en) 2016-04-28
US12435305B2 (en) 2025-10-07
IL251819A0 (en) 2017-06-29
CN113105992A (zh) 2021-07-13
ES2931455T3 (es) 2022-12-29
AU2015336130B2 (en) 2020-07-09
TW202026016A (zh) 2020-07-16
SG10201801943SA (en) 2018-05-30
IL251819B (en) 2020-11-30
JP6672287B2 (ja) 2020-03-25
HUE060385T2 (hu) 2023-02-28
JP2020103307A (ja) 2020-07-09
JP2017531444A (ja) 2017-10-26
JP6994526B2 (ja) 2022-02-21
AU2015336130A1 (en) 2017-06-08
BR112017008252B1 (pt) 2022-03-03
CN107109322B (zh) 2021-04-06
TWI740417B (zh) 2021-09-21
DK3209765T3 (da) 2022-11-28
US20210002601A1 (en) 2021-01-07
US20160115438A1 (en) 2016-04-28
KR102465762B1 (ko) 2022-11-09
BR112017008252A2 (pt) 2017-12-26

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