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MX2017004383A - Proceso para preparar 1-(3,5-diclorofenil)-2,2,2-trifluoroetanona y sus derivados. - Google Patents

Proceso para preparar 1-(3,5-diclorofenil)-2,2,2-trifluoroetanona y sus derivados.

Info

Publication number
MX2017004383A
MX2017004383A MX2017004383A MX2017004383A MX2017004383A MX 2017004383 A MX2017004383 A MX 2017004383A MX 2017004383 A MX2017004383 A MX 2017004383A MX 2017004383 A MX2017004383 A MX 2017004383A MX 2017004383 A MX2017004383 A MX 2017004383A
Authority
MX
Mexico
Prior art keywords
formula
compound
fluoro
chloro
hydrogen
Prior art date
Application number
MX2017004383A
Other languages
English (en)
Other versions
MX386842B (es
Inventor
Gribkov Denis
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of MX2017004383A publication Critical patent/MX2017004383A/es
Publication of MX386842B publication Critical patent/MX386842B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/08—Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/807—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen all halogen atoms bound to the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se describe un proceso para preparar un compuesto de fórmula (I) (ver Fórmula) donde R1 es hidrógeno, fluoro o cloro; el proceso comprende: a) hacer reaccionar un compuesto de fórmula (II) (ver Fórmula) donde R1 es hidrógeno, fluoro o cloro; con un agente de nitración para obtener el compuesto de fórmula (III) (ver Fórmula) donde R1 es hidrógeno, fluoro o cloro; b) hacer reaccionar el compuesto de fórmula (III) con ácido tricloroisocianúrico en presencia de ácido sulfúrico o ácido sulfúrico fumante para obtener el compuesto de fórmula (IV) (ver Fórmula) donde R1 es hidrógeno, fluoro o cloro; y c) hacer reaccionar el compuesto de fórmula (III) con cloro gaseoso a una temperatura de 180 °C a 250 °C para obtener el compuesto de fórmula (I).
MX2017004383A 2014-10-14 2015-10-07 Proceso para preparar 1-(3,5-diclorofenil)-2,2,2-trifluoroetanona y sus derivados. MX386842B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14188744 2014-10-14
PCT/EP2015/073118 WO2016058881A2 (en) 2014-10-14 2015-10-07 Process for the preparation of halo-substituted benzenes

Publications (2)

Publication Number Publication Date
MX2017004383A true MX2017004383A (es) 2017-06-22
MX386842B MX386842B (es) 2025-03-19

Family

ID=51690931

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017004383A MX386842B (es) 2014-10-14 2015-10-07 Proceso para preparar 1-(3,5-diclorofenil)-2,2,2-trifluoroetanona y sus derivados.
MX2021002896A MX2021002896A (es) 2014-10-14 2017-04-04 Proceso para preparar 1-(3,5-diclorofenil)-2,2,2-trifluoroetanona y sus derivados.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021002896A MX2021002896A (es) 2014-10-14 2017-04-04 Proceso para preparar 1-(3,5-diclorofenil)-2,2,2-trifluoroetanona y sus derivados.

Country Status (17)

Country Link
US (1) US10040745B2 (es)
EP (2) EP3207023B1 (es)
JP (2) JP6728151B2 (es)
KR (4) KR20230117260A (es)
CN (2) CN109665956A (es)
BR (1) BR112017007506B1 (es)
DK (1) DK3207023T3 (es)
ES (1) ES2755333T3 (es)
HR (1) HRP20192143T1 (es)
HU (1) HUE046755T2 (es)
IL (2) IL251176B (es)
MX (2) MX386842B (es)
PL (1) PL3207023T3 (es)
RS (1) RS59795B1 (es)
SI (1) SI3207023T1 (es)
TW (2) TWI670256B (es)
WO (1) WO2016058881A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020164218A1 (en) * 2019-02-15 2020-08-20 Fujian Yongjing Technology Co., Ltd New process for friedel-crafts reaction, and catalyst therefore
CN112110806B (zh) * 2020-09-10 2022-11-15 浙江永太科技股份有限公司 一种1-(3,5-二氯-4-氟-苯基)-2,2,2-三氟乙酮的制备方法及中间体
WO2022061914A1 (zh) * 2020-09-28 2022-03-31 台州臻挚生物科技有限公司 一种3,5-二卤三氟苯乙酮及其衍生物的制备方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60246327A (ja) 1984-05-22 1985-12-06 Asahi Glass Co Ltd 芳香族塩素化合物の製造方法
JPH03275646A (ja) * 1990-03-27 1991-12-06 Asahi Glass Co Ltd フッ素化安息香酸類の製造方法
JPH08259507A (ja) * 1995-03-24 1996-10-08 Nissan Chem Ind Ltd アセトフェノン誘導体のニトロ化方法
JPH08268975A (ja) * 1995-03-30 1996-10-15 Nissan Chem Ind Ltd ニトロハロゲノアセトフェノン誘導体の製造法
KR100240198B1 (ko) * 1997-08-09 2000-01-15 김충섭 트리플루오프메틸기가 치환된 알케닐기를 갖는 신규의 프로페노 익 에스테르 및 아미드 유도체
CN100400529C (zh) * 2003-10-08 2008-07-09 中国科学院化学研究所 含氟芳香族有机四酸二酐及制备方法和用途
AU2006285613B2 (en) 2005-09-02 2011-11-17 Nissan Chemical Corporation Isoxazoline-substituted benzamide compound and harmful organism-controlling agent
BRPI0710380A2 (pt) * 2006-04-20 2011-08-09 Du Pont composto, composição, composição de controle de pragas, invertebradas, de pulverização, de isca, dispositivo de armadilha, métodos de controle, métodos de proteção, semente tratada e composição de proteção
CN101177379A (zh) 2006-11-10 2008-05-14 浙江富盛控股集团有限公司 一种2,4,6-三氯氟苯的制备方法
CN101377862A (zh) 2007-08-31 2009-03-04 张帝 一种密码防窥的技术方法
JP5472638B2 (ja) * 2008-03-18 2014-04-16 日産化学工業株式会社 １−（置換フェニル）−１−置換シリルエーテル、アルコールまたはケトンの製造方法および中間体
EP2305672B1 (en) * 2008-06-13 2019-03-27 Shionogi & Co., Ltd. SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING ß-SECRETASE-INHIBITING ACTIVITY
CN101337862A (zh) 2008-08-08 2009-01-07 浙江富盛控股集团有限公司 一种2,6-二氯氟苯的制备方法
WO2010083316A2 (en) * 2009-01-14 2010-07-22 Dow Agrosciences Llc Fungicidal compositions including hydrazone derivatives and copper
GB0917775D0 (en) * 2009-10-09 2009-11-25 Btg Int Ltd Novel pharmaceutical compounds
DE102009046115A1 (de) 2009-10-28 2011-09-08 Bayer Schering Pharma Aktiengesellschaft Substituierte 3-Phenylpropansäuren und ihre Verwendung
WO2011071057A1 (ja) * 2009-12-09 2011-06-16 塩野義製薬株式会社 含硫黄複素環誘導体を含有するアルツハイマー症の治療用または予防用医薬組成物
JP2012082186A (ja) * 2010-09-15 2012-04-26 Bayer Cropscience Ag 殺虫性アリールピロリジン類
CN103282345A (zh) * 2010-11-03 2013-09-04 巴斯夫欧洲公司 制备取代的异噁唑啉化合物及其前体4-氯-、4-溴-或4-碘苯甲醛肟的方法
CA2829149A1 (en) * 2011-03-10 2012-09-13 Novartis Ag Isoxazole derivatives
JP6124012B2 (ja) * 2011-05-26 2017-05-10 日産化学工業株式会社 １−（２−アミノ−置換フェニル）−２−ハロ−２，２−ジフルオロエタノン化合物及び１−（置換フェニル）−２−ハロ−２，２−ジフルオロエタノン化合物の製造方法
US9156852B2 (en) 2011-12-30 2015-10-13 Hanmi Pharm. Co., Ltd Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases
CN103664511B (zh) 2013-12-13 2015-07-08 浙江林江化工股份有限公司 一种3,5-二氯-4-氟溴苯的制备方法

Also Published As

Publication number Publication date
WO2016058881A2 (en) 2016-04-21
MX2021002896A (es) 2021-07-15
CN109665956A (zh) 2019-04-23
EP3207023A2 (en) 2017-08-23
ES2755333T3 (es) 2020-04-22
EP3597627A1 (en) 2020-01-22
IL272451A (en) 2020-03-31
DK3207023T3 (da) 2019-12-09
KR20170070038A (ko) 2017-06-21
HRP20192143T1 (hr) 2020-02-21
EP3207023B1 (en) 2019-09-18
HUE046755T2 (hu) 2020-03-30
KR20230117260A (ko) 2023-08-07
WO2016058881A3 (en) 2016-06-09
IL251176B (en) 2020-06-30
CN106795093B (zh) 2019-05-28
JP6987930B2 (ja) 2022-01-05
US20170217865A1 (en) 2017-08-03
JP6728151B2 (ja) 2020-07-22
TW201623207A (zh) 2016-07-01
SI3207023T1 (sl) 2020-07-31
PL3207023T3 (pl) 2020-01-31
TWI687404B (zh) 2020-03-11
KR20250065736A (ko) 2025-05-13
BR112017007506B1 (pt) 2021-02-02
IL251176A0 (en) 2017-05-29
JP2020183395A (ja) 2020-11-12
RS59795B1 (sr) 2020-02-28
TW201930246A (zh) 2019-08-01
KR102436959B1 (ko) 2022-08-25
KR20220051422A (ko) 2022-04-26
TWI670256B (zh) 2019-09-01
MX386842B (es) 2025-03-19
CN106795093A (zh) 2017-05-31
US10040745B2 (en) 2018-08-07
BR112017007506A2 (pt) 2019-06-18
JP2017530998A (ja) 2017-10-19

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