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MX2017002768A - Agentes antivirales y usos de los mismos. - Google Patents

Agentes antivirales y usos de los mismos.

Info

Publication number
MX2017002768A
MX2017002768A MX2017002768A MX2017002768A MX2017002768A MX 2017002768 A MX2017002768 A MX 2017002768A MX 2017002768 A MX2017002768 A MX 2017002768A MX 2017002768 A MX2017002768 A MX 2017002768A MX 2017002768 A MX2017002768 A MX 2017002768A
Authority
MX
Mexico
Prior art keywords
antiviral agents
compounds
modulators
exhibit
activity
Prior art date
Application number
MX2017002768A
Other languages
English (en)
Inventor
El-Deeb Ibrahim
WINGER Moritz
Guillon Patrice
Dirr Larissa
Von Itzstein Mark
Original Assignee
Univ Griffith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Griffith filed Critical Univ Griffith
Publication of MX2017002768A publication Critical patent/MX2017002768A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a compuestos que han sido encontrados que exhiben un efecto antiviral. Los compuestos son moduladores de la actividad de las enzimas hemaglutinina y/o neuraminidasa virales.
MX2017002768A 2014-09-05 2015-09-07 Agentes antivirales y usos de los mismos. MX2017002768A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL2013420A NL2013420B1 (en) 2014-09-05 2014-09-05 Antiviral agents and uses thereof.
PCT/AU2015/050526 WO2016033660A1 (en) 2014-09-05 2015-09-07 Antiviral agents and uses thereof

Publications (1)

Publication Number Publication Date
MX2017002768A true MX2017002768A (es) 2017-10-31

Family

ID=52001031

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017002768A MX2017002768A (es) 2014-09-05 2015-09-07 Agentes antivirales y usos de los mismos.

Country Status (16)

Country Link
US (1) US10028938B2 (es)
EP (1) EP3189050B1 (es)
JP (2) JP2017525746A (es)
KR (1) KR102604939B1 (es)
CN (1) CN107108584B (es)
AU (1) AU2015311626B2 (es)
BR (1) BR112017004253B1 (es)
CA (1) CA2959548C (es)
DK (1) DK3189050T3 (es)
ES (1) ES2788475T3 (es)
HU (1) HUE049991T2 (es)
MX (1) MX2017002768A (es)
NL (1) NL2013420B1 (es)
RU (1) RU2730453C2 (es)
SG (1) SG11201701717UA (es)
WO (1) WO2016033660A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018273411B2 (en) 2017-05-25 2022-12-01 The Governors Of The University Of Alberta Methods of preventing or treating atherosclerosis with inhibitors of specific isoenzymes of human neuraminidase
WO2021016670A1 (en) * 2019-07-30 2021-02-04 Griffith University Antiviral agents and uses thereof
AU2022213476A1 (en) * 2021-01-29 2023-08-17 Griffith University Antiviral agents and uses thereof
WO2024026536A1 (en) * 2022-08-03 2024-02-08 Griffith University Antiviral compounds and uses thereof
IT202200019842A1 (it) * 2022-09-27 2024-03-27 Policlinico San Donato S P A Agenti antivirali per l’uso contro i virus della famiglia dei paramyxoviridae

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK282950B6 (sk) * 1990-04-24 2003-01-09 Biota Scientific Management Pty Ltd Deriváty alfa-D-neuramínovej kyseliny, spôsob ich prípravy, ich použitie a farmaceutické prípravky na ich báze
AU7990000A (en) 1999-10-19 2001-04-30 Abbott Laboratories Neuraminidase inhibitors
US7045535B2 (en) * 2001-03-08 2006-05-16 Biocryst Pharmaceuticals, Inc. Compounds useful for inhibiting paramyxovirus neuraminidase
CN101787008A (zh) 2009-01-23 2010-07-28 中国科学院上海药物研究所 N-乙酰神经氨酸类化合物、其药物组合物及其制备方法和用途
EP2454268B1 (en) * 2009-07-15 2014-09-10 The University Of British Columbia 2,3-fluorinated glycosides as neuraminidase inhibitors and their use as anti-virals

Also Published As

Publication number Publication date
KR102604939B1 (ko) 2023-11-21
AU2015311626B2 (en) 2020-03-12
CA2959548C (en) 2023-10-17
CN107108584A (zh) 2017-08-29
US20170290809A1 (en) 2017-10-12
JP2017525746A (ja) 2017-09-07
NL2013420B1 (en) 2016-09-27
SG11201701717UA (en) 2017-04-27
CN107108584B (zh) 2021-01-22
WO2016033660A1 (en) 2016-03-10
EP3189050A1 (en) 2017-07-12
ES2788475T3 (es) 2020-10-21
BR112017004253A2 (pt) 2017-12-12
AU2015311626A1 (en) 2017-03-23
EP3189050A4 (en) 2018-02-28
CA2959548A1 (en) 2016-03-10
RU2017110512A (ru) 2018-10-05
BR112017004253B1 (pt) 2023-01-31
RU2730453C2 (ru) 2020-08-24
DK3189050T3 (da) 2020-04-27
JP2021001204A (ja) 2021-01-07
EP3189050B1 (en) 2020-02-05
RU2017110512A3 (es) 2019-02-19
HUE049991T2 (hu) 2020-11-30
US10028938B2 (en) 2018-07-24
JP7206241B2 (ja) 2023-01-17
KR20170068464A (ko) 2017-06-19

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