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MX2017001620A - Formas cristalinas de inhibidores de glutaminasa. - Google Patents

Formas cristalinas de inhibidores de glutaminasa.

Info

Publication number
MX2017001620A
MX2017001620A MX2017001620A MX2017001620A MX2017001620A MX 2017001620 A MX2017001620 A MX 2017001620A MX 2017001620 A MX2017001620 A MX 2017001620A MX 2017001620 A MX2017001620 A MX 2017001620A MX 2017001620 A MX2017001620 A MX 2017001620A
Authority
MX
Mexico
Prior art keywords
crystal forms
glutaminase inhibitors
methods
crystalline
crystalline salt
Prior art date
Application number
MX2017001620A
Other languages
English (en)
Inventor
J Springer James
F Stanton Timothy
N Williams Jacqueline
Original Assignee
Calithera Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calithera Biosciences Inc filed Critical Calithera Biosciences Inc
Publication of MX2017001620A publication Critical patent/MX2017001620A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La invención se refiere a las sales cristalinas de un compuesto que tiene la estructura de la Fórmula (I), los métodos para su preparación y las composiciones farmacéuticas relacionadas que comprenden la sal cristalina. La invención de refiere además a los métodos de tratamiento o prevención del cáncer o un trastorno inmunitario o neurológico, que comprende administrar una sal cristalina de la invención.
MX2017001620A 2014-08-07 2015-08-07 Formas cristalinas de inhibidores de glutaminasa. MX2017001620A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462034547P 2014-08-07 2014-08-07
PCT/US2015/044301 WO2016022969A1 (en) 2014-08-07 2015-08-07 Crystal forms of glutaminase inhibitors

Publications (1)

Publication Number Publication Date
MX2017001620A true MX2017001620A (es) 2017-05-10

Family

ID=55264662

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017001620A MX2017001620A (es) 2014-08-07 2015-08-07 Formas cristalinas de inhibidores de glutaminasa.

Country Status (13)

Country Link
US (2) US10316030B2 (es)
EP (1) EP3193876B1 (es)
JP (3) JP6889101B2 (es)
KR (1) KR20170082494A (es)
CN (1) CN106999490A (es)
AU (2) AU2015300825B2 (es)
BR (1) BR112017002403A2 (es)
CA (1) CA2957225A1 (es)
EA (1) EA037738B1 (es)
IL (1) IL250391B (es)
MX (1) MX2017001620A (es)
SG (1) SG11201700816YA (es)
WO (1) WO2016022969A1 (es)

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Also Published As

Publication number Publication date
WO2016022969A1 (en) 2016-02-11
KR20170082494A (ko) 2017-07-14
JP6889101B2 (ja) 2021-06-18
CN106999490A (zh) 2017-08-01
US10676472B2 (en) 2020-06-09
CA2957225A1 (en) 2016-02-11
US20170226101A1 (en) 2017-08-10
BR112017002403A2 (pt) 2017-12-05
US20190359607A1 (en) 2019-11-28
JP2017523991A (ja) 2017-08-24
JP2021165286A (ja) 2021-10-14
IL250391A0 (en) 2017-03-30
IL250391B (en) 2021-10-31
SG11201700816YA (en) 2017-02-27
EP3193876A1 (en) 2017-07-26
EP3193876B1 (en) 2022-01-12
EA201790337A1 (ru) 2017-09-29
AU2015300825A1 (en) 2017-03-09
JP2020037588A (ja) 2020-03-12
EP3193876A4 (en) 2017-12-27
EA037738B1 (ru) 2021-05-17
US10316030B2 (en) 2019-06-11
AU2015300825B2 (en) 2019-10-10
AU2019284149A1 (en) 2020-01-30

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