[go: up one dir, main page]

MX2017000449A - Dispositivos, sistemas y metodos mejorados para detectar un diferencial bilateral en umbral de deteccion olfativa para odorantes puros. - Google Patents

Dispositivos, sistemas y metodos mejorados para detectar un diferencial bilateral en umbral de deteccion olfativa para odorantes puros.

Info

Publication number
MX2017000449A
MX2017000449A MX2017000449A MX2017000449A MX2017000449A MX 2017000449 A MX2017000449 A MX 2017000449A MX 2017000449 A MX2017000449 A MX 2017000449A MX 2017000449 A MX2017000449 A MX 2017000449A MX 2017000449 A MX2017000449 A MX 2017000449A
Authority
MX
Mexico
Prior art keywords
systems
methods
olfactory
detection threshold
detecting
Prior art date
Application number
MX2017000449A
Other languages
English (en)
Inventor
B Mills Gregory
Original Assignee
Inspired Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inspired Tech Inc filed Critical Inspired Tech Inc
Publication of MX2017000449A publication Critical patent/MX2017000449A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4005Detecting, measuring or recording for evaluating the nervous system for evaluating the sensory system
    • A61B5/4011Evaluating olfaction, i.e. sense of smell
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4088Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7246Details of waveform analysis using correlation, e.g. template matching or determination of similarity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271Specific aspects of physiological measurement analysis
    • A61B5/7282Event detection, e.g. detecting unique waveforms indicative of a medical condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/08Inhaling devices inserted into the nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0013Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0015Details of inhalators; Constructional features thereof with inhalation check valves located upstream of the dispenser, i.e. not traversed by the product
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0013Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043Non-destructive separation of the package, e.g. peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0016Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the smell sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Artificial Intelligence (AREA)
  • Signal Processing (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Developmental Disabilities (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Otolaryngology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

El presente sistema se dirige en varias modalidades a dispositivos, sistemas y métodos para detección, evaluación y/o monitoreo de disfunción olfativa al medir y determinar el umbral de detección olfativa del paciente para la fosa nasal derecha y la izquierda. De manera más específica. la presente invención se refiere a dispositivos, sistemas y métodos para detectar un diferencial asimétrico en un umbral de detección olfativa del paciente (fosa nasal izquierda contra derecha), el cual, cuando está presente, puede usarse como una herramienta para clasificar, detectar, diagnosticar y/o monitorear deterioro olfativo relativo que resulta de la enfermedad Alzheimer. Una modalidad preferida comprende arreglar en cascada aromas al administrar en serie más de un odorante puro a las fosas nasales del paciente, izquierda contra derecha, con medición del tiempo, o número de inhalaciones, requeridas para notar cognitivamente la presencia de odorantes puros.
MX2017000449A 2014-07-11 2015-07-10 Dispositivos, sistemas y metodos mejorados para detectar un diferencial bilateral en umbral de deteccion olfativa para odorantes puros. MX2017000449A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462023352P 2014-07-11 2014-07-11
US201562108239P 2015-01-27 2015-01-27
US14/795,606 US9717454B2 (en) 2014-07-11 2015-07-09 Method of ruling out Alzheimer's disease
PCT/US2015/039875 WO2016007817A1 (en) 2014-07-11 2015-07-10 Improved devices, systems and methods for detecting a bilateral differential in olfactory detection threshold for pure odorants

Publications (1)

Publication Number Publication Date
MX2017000449A true MX2017000449A (es) 2017-08-14

Family

ID=55064938

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017000449A MX2017000449A (es) 2014-07-11 2015-07-10 Dispositivos, sistemas y metodos mejorados para detectar un diferencial bilateral en umbral de deteccion olfativa para odorantes puros.

Country Status (8)

Country Link
US (4) US9717454B2 (es)
EP (2) EP3166669A4 (es)
JP (1) JP6666327B2 (es)
AU (1) AU2015287657A1 (es)
CA (1) CA2954761A1 (es)
IL (1) IL249817A0 (es)
MX (1) MX2017000449A (es)
WO (1) WO2016007817A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016161261A1 (en) 2015-04-03 2016-10-06 Olfaxis, Llc Apparatus, method, and system for testing human olfactory systems
US10682087B2 (en) 2015-04-03 2020-06-16 Olfaxis, Llc Apparatus, method, and system for testing human olfactory systems
US10695510B2 (en) * 2015-12-07 2020-06-30 Vapium Inc. Aromatherapy vaporization device
EP3245944A1 (en) * 2016-05-20 2017-11-22 Institut Pasteur Olfactory means for the diagnosis of neurological complications of nervous system infection
US10757978B2 (en) 2016-09-15 2020-09-01 Altria Client Services Llc Electronic aerosol-generating smoking device
MX2019002790A (es) 2016-09-15 2019-05-09 Philip Morris Products Sa Dispositivo para fumar generador de aerosol electronico.
US10667739B2 (en) * 2017-07-21 2020-06-02 Shimadzu Corporation Olfaction test device
JP7207312B2 (ja) 2017-09-15 2023-01-18 ソニーグループ株式会社 香料保持構造体、香料保持構造体の製造方法、及び香り提供装置
US11954564B2 (en) 2017-09-21 2024-04-09 International Business Machines Corporation Implementing dynamically and automatically altering user profile for enhanced performance
US11986310B2 (en) 2017-09-29 2024-05-21 Olfaxis, Llc Olfactory test systems and methods
US20190142329A1 (en) * 2017-11-14 2019-05-16 Inspired Life Medical Inc. Methods and system for detecting living, non-demented patients who have alzheimer's disease neuropathology for alzheimer's disease
US10709375B2 (en) * 2018-07-10 2020-07-14 Inspired Life Medical, Inc. Devices, systems and methods for testing for degenerative disorders of the central nervous system
KR102184533B1 (ko) * 2018-11-23 2020-11-30 전남대학교병원 후각 역치 및 위양성 자가검사장치 및 그 장치를 이용한 후각 역치 및 위양성 자가검사방법
CN110353632B (zh) * 2019-07-24 2024-01-26 中国科学院心理研究所 一种气味呈现工具及其嗅觉测试与训练工具
JP7343161B2 (ja) * 2019-09-12 2023-09-12 学校法人立命館 匂い物質提示装置
US12329901B1 (en) 2019-12-13 2025-06-17 Trudell Medical International Inc. Medicament delivery device with vibrating air flow
CN111398524B (zh) * 2020-04-01 2022-10-04 北京燕京啤酒股份有限公司 一种啤酒关键风味成分识别阈值及其与酒花香气的协调性评价方法
US11786164B2 (en) * 2020-08-18 2023-10-17 Indian Institute Of Science Education And Research Olfactory-action meter for precise quantification of olfactory dysfunctions and neurocognitive deficits
KR20230077746A (ko) * 2020-11-05 2023-06-01 필립모리스 프로덕츠 에스.에이. 개구부를 포함하는 가요성 멤브레인을 갖는 에어로졸 발생 장치
US20230173220A1 (en) * 2021-12-07 2023-06-08 Accenture Global Solutions Limited Aroma training using augmented reality
US12213796B2 (en) * 2021-12-07 2025-02-04 Accenture Global Solutions Limited Aroma training using virtual reality
CN116035537B (zh) * 2023-03-31 2023-09-01 广州中医药大学第一附属医院 一种用于糖尿病认知障碍早期预测系统

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2210298A5 (es) 1972-12-08 1974-07-05 Commissariat Energie Atomique
FR2414201A2 (fr) 1978-01-10 1979-08-03 Commissariat Energie Atomique Olfactometre differentiel
US5204096A (en) 1984-03-07 1993-04-20 New York Blood Center, Inc. Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers
US4934386A (en) 1987-10-13 1990-06-19 R. J. Reynolds Tobacco Company Apparatus for assessing responses of humans to stimulants
US5565148A (en) 1995-03-16 1996-10-15 Minnesota Mining And Manufacturing Company Device for selectively providing a multiplicity of aromas
US6325475B1 (en) 1996-09-06 2001-12-04 Microfab Technologies Inc. Devices for presenting airborne materials to the nose
EP1107800A1 (en) 1998-08-28 2001-06-20 Aroma Technology Limited Odor dispensing device and odor dispensing cartridge
AU3741100A (en) 1999-03-12 2000-09-28 Microscent, Llc. Methods and apparatus for localized delivery of scented aerosols
EP1098195A3 (en) 1999-11-04 2001-06-13 Givaudan SA A device for olfactory judgement of an odorous substance, use thereof and a method of operating the device
US6595037B2 (en) 2001-08-07 2003-07-22 Mcginley Charles M. Portable odor detecting and measuring device
US8826723B2 (en) 2012-03-15 2014-09-09 Nutech Ventures Assessing odors
US20030113701A1 (en) 2001-12-13 2003-06-19 William Gartner Self-scoring method and apparatus for early self-screening of neurological disease
AU2003207552A1 (en) 2002-01-29 2003-09-02 James D. Talton Methods of collecting and analyzing human breath
US20050192482A1 (en) 2004-01-30 2005-09-01 Endoluminal Therapeutics, Inc. Disposable sheath for specula
US7007694B2 (en) 2004-05-21 2006-03-07 Acoba, Llc Nasal cannula
WO2006095816A1 (ja) 2005-03-11 2006-09-14 Akira Tomono 霧発生装置、および、霧放出演出装置
WO2006135368A1 (en) 2005-06-10 2006-12-21 The Trustrees Of Columbia University In The City Of New York Olfactory identification tests for cognitive diseases and disorders
US9056179B2 (en) 2006-05-31 2015-06-16 Acoba, L.L.C. Hose connection system for narially sensitive diagnostic devices
US8075669B2 (en) * 2007-04-23 2011-12-13 Gore Enterprise Holdings, Inc. Composite material
US8231542B2 (en) 2008-08-27 2012-07-31 Lifeline Biotechnologies, Inc. System for analyzing thermal data based on breast surface temperature to determine suspect conditions
JP5109932B2 (ja) * 2008-11-04 2012-12-26 株式会社島津製作所 におい測定装置
US9295806B2 (en) 2009-03-06 2016-03-29 Imotions A/S System and method for determining emotional response to olfactory stimuli
US8429950B2 (en) 2009-08-06 2013-04-30 Don Wright & Associates, L.L.C. Field olfactometer with differential flow-based dynamic dilution
WO2011035284A1 (en) 2009-09-21 2011-03-24 Monell Chemical Senses Center Mri compatible and air-actuated olfactometer
US8469293B2 (en) 2010-04-16 2013-06-25 Richard L. Doty Digital odor generator
US20130012828A1 (en) 2011-07-09 2013-01-10 3 Inventing Guys, Llc Method and System for Measuring Nasal Resistance to Airflow
FR2988845B1 (fr) 2012-04-03 2014-04-11 Univ Franche Comte Dispositif pour evaluer la perception olfactive.
CN105307718B (zh) 2013-04-19 2018-05-11 奥库利维公司 鼻刺激装置和方法

Also Published As

Publication number Publication date
IL249817A0 (en) 2017-03-30
US9717454B2 (en) 2017-08-01
US20160249845A1 (en) 2016-09-01
US10426395B2 (en) 2019-10-01
EP3166669A1 (en) 2017-05-17
US20160249844A1 (en) 2016-09-01
US9936913B2 (en) 2018-04-10
AU2015287657A1 (en) 2017-02-02
JP2017529885A (ja) 2017-10-12
US20170258387A1 (en) 2017-09-14
WO2016007817A1 (en) 2016-01-14
CA2954761A1 (en) 2016-01-14
US20160015309A1 (en) 2016-01-21
JP6666327B2 (ja) 2020-03-13
EP3166669A4 (en) 2018-08-08
EP3395387A1 (en) 2018-10-31

Similar Documents

Publication Publication Date Title
MX2017000449A (es) Dispositivos, sistemas y metodos mejorados para detectar un diferencial bilateral en umbral de deteccion olfativa para odorantes puros.
MX2016005337A (es) Dispositivos, sistemas y metodos para detectar un diferencial bilateral en el umbral olfativo de olores puros.
SG10201709261RA (en) Biomedical sensing methods and apparatus for the detection and prevention of lung cancer states
GB2565683A (en) System for determining airway patency
EP4681629A3 (en) Exhaled gas measurement compensation during high flow respiratory therapy
EP4338672A3 (en) System for screening delirium patients for the presence of encephalopathy
MX386758B (es) Sistemas y métodos para monitorear y diagnosticar la salud del transformador.
MX392755B (es) Sistema de monitoreo de paciente.
FR2924847B1 (fr) Procede et equipement de detection de situation critique d'un sujet
MX364090B (es) Dispositivo y método para determinar presión de dióxido de carbono parcial en un sujeto de interés.
WO2016090260A8 (en) Inhalation monitoring system and method
EP4582559A3 (en) Biomarkers of traumatic brain injury
EP4406591A3 (en) Medical device operational modes
MY187320A (en) Electronic vapour provision system
NZ738443A (en) Pressure sensor evaluation for respiratory apparatus
BR112015028545A2 (pt) dispositivo de detecção, sistema de detecção remoto distribuído
BR112015016305A2 (pt) controlador de área mecanizada
MX373720B (es) Indicador de presion para un dispositivo de presion espiratoria positiva oscilante.
MX394734B (es) Aparato y método para monitorizar el suministro de óxido nítrico.
WO2013013782A3 (de) Verfahren und vorrichtung zur überwachung des harnblasenfüllstandes eines patienten
BR112012016767A2 (pt) Método para diagnosticar se um paciente sofre de uma condição hepática ou do fígado, método para detectar o desenvolvimento de uma patologia do fígado, método para deter5 minar o risco de um paciente para uma condição do fígado e sistema para diagnosticar o estado de saúde hepática
EA201690477A1 (ru) Способ и система калибровки расхода газа при использовании датчика расхода на аппарате для ингаляционного наркоза
BR112017008639A2 (pt) purificador de água, e método para a detecção da vida útil de um cartucho de filtro
SG11201907467SA (en) Train presence detection apparatus
WO2018098109A3 (en) Methods of identifying schizophrenia patients at risk for relapse