MX2017000083A - Compuestos de platino, composiciones y usos de estos. - Google Patents
Compuestos de platino, composiciones y usos de estos.Info
- Publication number
- MX2017000083A MX2017000083A MX2017000083A MX2017000083A MX2017000083A MX 2017000083 A MX2017000083 A MX 2017000083A MX 2017000083 A MX2017000083 A MX 2017000083A MX 2017000083 A MX2017000083 A MX 2017000083A MX 2017000083 A MX2017000083 A MX 2017000083A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- platinum compounds
- reacting
- protein
- antibody
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 229940045985 antineoplastic platinum compound Drugs 0.000 title 1
- 150000003058 platinum compounds Chemical class 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108091023037 Aptamer Proteins 0.000 abstract 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 abstract 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- -1 antibody Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- NDBYXKQCPYUOMI-UHFFFAOYSA-N platinum(4+) Chemical compound [Pt+4] NDBYXKQCPYUOMI-UHFFFAOYSA-N 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Las presentes instrucciones se relacionan con compuestos y composiciones para el tratamiento de cánceres. En algunas modalidades, la composición comprende un complejo de platino (IV) que tiene al menos un grupo reactivo adecuado para la reacción con un grupo funcional en una proteína, proteína diseñada genéticamente, anticuerpo, fragmento de anticuerpo, péptido, agonista, antagonista, aptámero o ligando que puede ser capaz de reconocer una población de células objetivo seleccionada y/o derivados/análogos/miméticos de estos.
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462015714P | 2014-06-23 | 2014-06-23 | |
| US201462034124P | 2014-08-06 | 2014-08-06 | |
| US201462035126P | 2014-08-08 | 2014-08-08 | |
| US201462035739P | 2014-08-11 | 2014-08-11 | |
| US201562150045P | 2015-04-20 | 2015-04-20 | |
| PCT/US2015/037071 WO2015200250A1 (en) | 2014-06-23 | 2015-06-23 | Platinum compounds, compositions, and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2017000083A true MX2017000083A (es) | 2017-05-30 |
Family
ID=54938720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017000083A MX2017000083A (es) | 2014-06-23 | 2015-06-23 | Compuestos de platino, composiciones y usos de estos. |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US9403858B2 (es) |
| EP (2) | EP3797768A1 (es) |
| JP (2) | JP6336681B2 (es) |
| KR (1) | KR101915452B1 (es) |
| CN (1) | CN106659706B (es) |
| AU (2) | AU2015280204B2 (es) |
| BR (1) | BR112016030310A2 (es) |
| CA (1) | CA2953350C (es) |
| IL (1) | IL249646B (es) |
| MX (1) | MX2017000083A (es) |
| NZ (1) | NZ727701A (es) |
| SG (1) | SG11201610656QA (es) |
| WO (1) | WO2015200250A1 (es) |
| ZA (1) | ZA201608543B (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015102922A1 (en) * | 2013-12-31 | 2015-07-09 | Blend Therapeutics, Inc. | Compounds, compositions, and methods for the treatment of cancers |
| WO2015200250A1 (en) * | 2014-06-23 | 2015-12-30 | Blend Therapeutics, Inc. | Platinum compounds, compositions, and uses thereof |
| WO2016209935A1 (en) * | 2015-06-23 | 2016-12-29 | Placon Therapeutics, Inc. | Platinum compounds, compositions, and uses thereof |
| US10342801B2 (en) | 2015-06-23 | 2019-07-09 | Placon Therapeutics, Inc. | Platinum compounds, compositions, and uses thereof |
| MX377528B (es) | 2015-12-09 | 2025-03-10 | Univ Wien Med | Compuestos de platino funcionalizados con monomaleimida para la terapia del cáncer. |
| CN105622674B (zh) * | 2016-02-29 | 2018-02-02 | 东南大学 | 一类含有生物活性基团的四价铂配合物及其制备方法 |
| CN106046062B (zh) * | 2016-07-01 | 2018-09-11 | 中国科学院上海药物研究所 | 两亲性奥沙利铂前体,其制备方法及用途 |
| CN110950915B (zh) * | 2019-12-24 | 2022-07-22 | 玉林师范学院 | 一种新型大黄酸类-铂(iv)前体抗癌配合物及其合成方法与应用 |
| CN111205331B (zh) * | 2020-02-24 | 2021-06-15 | 南京大学 | 一种具有抗耐药性功能的抗肿瘤四价铂配合物及制备方法 |
| WO2022052014A1 (zh) * | 2020-09-11 | 2022-03-17 | 上海海聚生物科技有限公司 | 一类治疗癌症用的铂类化合物及其制备方法 |
| CN114539320B (zh) * | 2020-11-25 | 2026-01-27 | 北京大学 | 辐射激活的四价铂配合物及其用途 |
| US20230042086A1 (en) * | 2021-07-23 | 2023-02-09 | The Procter & Gamble Company | Compositions for controlling arthropods |
| CN114249773B (zh) * | 2021-12-06 | 2022-12-30 | 苏州大学 | 释放一氧化氮的四价铂类化合物及其制备和应用 |
| CN114230616B (zh) * | 2022-02-22 | 2022-04-29 | 江苏南创化学与生命健康研究院有限公司 | 一种癌细胞靶向的抗癌Pt配合物及其制备方法与应用 |
| US11999924B2 (en) | 2022-06-27 | 2024-06-04 | The Procter & Gamble Company | Stable aqueous surfactant compositions |
| CN117820080A (zh) * | 2023-01-10 | 2024-04-05 | 陈学军 | 一种Reppe法改良式BDO生产工艺 |
| CN116621900B (zh) * | 2023-01-10 | 2024-05-07 | 河南大学 | 一种基于调控Mucin型O-糖基化靶向CRPC的四价铂氨基己糖配合物及其应用 |
| US12171841B1 (en) | 2024-07-19 | 2024-12-24 | Imam Mohammad Ibn Saud Islamic University | Synthesis and characterization of glauconite-based silicate nanorods as anticancer agent |
| US12427104B1 (en) | 2025-04-01 | 2025-09-30 | Ingenus Pharmaceuticals, Llc | Injectable carboplatin formulations |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4550187A (en) | 1984-04-12 | 1985-10-29 | The Research Foundation Of State University Of New York | Synthesis of platinum (IV) antineoplastic agents |
| US5041578A (en) | 1988-11-22 | 1991-08-20 | Board Of Regents, The University Of Texas System | Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents |
| US5622929A (en) | 1992-01-23 | 1997-04-22 | Bristol-Myers Squibb Company | Thioether conjugates |
| ATE197249T1 (de) | 1994-08-08 | 2000-11-15 | Debiopharm Sa | Stabiles arzneimittel enthaltend oxaliplatin |
| US20040220078A1 (en) | 2001-03-02 | 2004-11-04 | Houssam Ibrahim | Device for packaging an oxaliplatinum solution |
| AU2003284885A1 (en) | 2002-10-21 | 2004-05-13 | Kensey Nash Corporation | Device and methods for sequential, regional delivery of multiple cytotoxic agents |
| US20060205810A1 (en) * | 2004-11-24 | 2006-09-14 | Schering Corporation | Platinum therapeutic combinations |
| WO2006066595A2 (en) | 2004-12-22 | 2006-06-29 | Novozymes A/S | Recombinant production of serum albumin |
| GB0522569D0 (en) | 2005-11-04 | 2005-12-14 | Univ Bath | Biocompatible drug delivery device |
| PE20142451A1 (es) | 2012-02-27 | 2015-02-04 | Amunix Operating Inc | Composiciones de conjugados de xten y metodos para realizar las mismas |
| US20130252832A1 (en) | 2012-03-22 | 2013-09-26 | Yale University | KRAS Variant and Tumor Biology |
| WO2013170069A1 (en) | 2012-05-09 | 2013-11-14 | Massachusetts Institute Of Technology | Medicament, method, and drug delivery device for treatment of ovarian cancer |
| RU2657591C2 (ru) | 2012-08-31 | 2018-06-14 | ТАРИС Биомедикал ЛЛК | Способ лечения рака мочевого пузыря оксалиплатином, соответствующее устройство его доставки, способ и устройство его введения |
| CA2944480C (en) | 2013-04-10 | 2021-05-18 | Massachusetts Institute Of Technology | Local drug delivery devices and methods for treating cancer |
| US20160166715A1 (en) | 2013-07-30 | 2016-06-16 | Tarveda Therapeutics, Inc. | Nanoparticle Diagnostic and Methods for Treating Disease |
| CN105744983B (zh) | 2013-08-12 | 2019-12-27 | 纳米医学系统公司 | 用于缓释在增溶剂中的低水溶性治疗剂的装置和方法 |
| WO2015102922A1 (en) * | 2013-12-31 | 2015-07-09 | Blend Therapeutics, Inc. | Compounds, compositions, and methods for the treatment of cancers |
| WO2015200250A1 (en) * | 2014-06-23 | 2015-12-30 | Blend Therapeutics, Inc. | Platinum compounds, compositions, and uses thereof |
| WO2016209935A1 (en) * | 2015-06-23 | 2016-12-29 | Placon Therapeutics, Inc. | Platinum compounds, compositions, and uses thereof |
| MX377528B (es) * | 2015-12-09 | 2025-03-10 | Univ Wien Med | Compuestos de platino funcionalizados con monomaleimida para la terapia del cáncer. |
-
2015
- 2015-06-23 WO PCT/US2015/037071 patent/WO2015200250A1/en not_active Ceased
- 2015-06-23 BR BR112016030310A patent/BR112016030310A2/pt not_active Application Discontinuation
- 2015-06-23 AU AU2015280204A patent/AU2015280204B2/en not_active Ceased
- 2015-06-23 SG SG11201610656QA patent/SG11201610656QA/en unknown
- 2015-06-23 CN CN201580044516.9A patent/CN106659706B/zh not_active Expired - Fee Related
- 2015-06-23 MX MX2017000083A patent/MX2017000083A/es unknown
- 2015-06-23 EP EP20206937.3A patent/EP3797768A1/en not_active Withdrawn
- 2015-06-23 CA CA2953350A patent/CA2953350C/en not_active Expired - Fee Related
- 2015-06-23 JP JP2017521071A patent/JP6336681B2/ja not_active Expired - Fee Related
- 2015-06-23 EP EP15811934.7A patent/EP3157515B1/en active Active
- 2015-06-23 NZ NZ727701A patent/NZ727701A/en not_active IP Right Cessation
- 2015-06-23 KR KR1020177001819A patent/KR101915452B1/ko not_active Expired - Fee Related
- 2015-11-18 US US14/944,610 patent/US9403858B2/en not_active Expired - Fee Related
-
2016
- 2016-06-10 US US15/179,701 patent/US9937187B2/en active Active
- 2016-12-12 ZA ZA2016/08543A patent/ZA201608543B/en unknown
- 2016-12-19 IL IL249646A patent/IL249646B/en active IP Right Grant
-
2017
- 2017-09-21 US US15/711,041 patent/US10322137B2/en active Active
-
2018
- 2018-05-02 JP JP2018088762A patent/JP6659764B2/ja not_active Expired - Fee Related
- 2018-09-28 AU AU2018236864A patent/AU2018236864A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL249646B (en) | 2019-05-30 |
| NZ727701A (en) | 2018-04-27 |
| US10322137B2 (en) | 2019-06-18 |
| CN106659706A (zh) | 2017-05-10 |
| US9403858B2 (en) | 2016-08-02 |
| JP2017522377A (ja) | 2017-08-10 |
| AU2015280204B2 (en) | 2018-10-18 |
| KR101915452B1 (ko) | 2018-11-06 |
| CA2953350A1 (en) | 2015-12-30 |
| US9937187B2 (en) | 2018-04-10 |
| KR20170021854A (ko) | 2017-02-28 |
| ZA201608543B (en) | 2019-04-24 |
| EP3157515B1 (en) | 2021-05-26 |
| EP3157515A1 (en) | 2017-04-26 |
| JP6336681B2 (ja) | 2018-06-06 |
| JP2018141000A (ja) | 2018-09-13 |
| WO2015200250A1 (en) | 2015-12-30 |
| CN106659706B (zh) | 2020-03-20 |
| US20160317549A1 (en) | 2016-11-03 |
| IL249646A0 (en) | 2017-02-28 |
| BR112016030310A2 (pt) | 2017-08-22 |
| EP3797768A1 (en) | 2021-03-31 |
| JP6659764B2 (ja) | 2020-03-04 |
| AU2015280204A1 (en) | 2017-01-12 |
| EP3157515A4 (en) | 2018-01-03 |
| CA2953350C (en) | 2019-11-26 |
| AU2018236864A1 (en) | 2018-10-18 |
| US20160068557A1 (en) | 2016-03-10 |
| SG11201610656QA (en) | 2017-01-27 |
| US20180008614A1 (en) | 2018-01-11 |
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