MX2016012525A - Anticuerpo anti-grpr, proceso de obtencion, proceso de deteccion, uso de anticuerpo, kit y construccion genetica. - Google Patents
Anticuerpo anti-grpr, proceso de obtencion, proceso de deteccion, uso de anticuerpo, kit y construccion genetica.Info
- Publication number
- MX2016012525A MX2016012525A MX2016012525A MX2016012525A MX2016012525A MX 2016012525 A MX2016012525 A MX 2016012525A MX 2016012525 A MX2016012525 A MX 2016012525A MX 2016012525 A MX2016012525 A MX 2016012525A MX 2016012525 A MX2016012525 A MX 2016012525A
- Authority
- MX
- Mexico
- Prior art keywords
- antibody
- grpr
- kit
- gene construct
- producing same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- G01N33/5755—
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/286—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against neuromediator receptors, e.g. serotonin receptor, dopamine receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Peptides Or Proteins (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
Abstract
La presente invención se refiere a un anticuerpo anti-GRPR obtenido a partir de un proceso que comprende la etapa de exposición de al menos un animal a un péptido con al menos 60% de identidad con la secuencia de SEQ ID NO: 1. La presente invención también describe un proceso para obtener anticuerpo anti-GRPR, un método de detección in vitro de lesiones displásicas y / o neoplásicas uterinas, el uso de anticuerpo anti-GRPR, un kit para la detección cualitativa y / o cuantitativa de las lesiones displásicas y / o neoplásicas uterinas, y una construcción genética para la expresión o la producción de péptido antigénico. La presente invención se basa en los campos de la Medicina, Inmunología y Biología Molecular.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR102014007315A BR102014007315A2 (pt) | 2014-03-27 | 2014-03-27 | kit e processo para detecção de lesões displásicas e/ou neoplásicas uterinas, peptídeo antigênico, construção gênica, anticorpo e processo para sua obtenção |
| PCT/BR2015/050034 WO2015143525A1 (pt) | 2014-03-27 | 2015-03-27 | Anticorpo anti-grpr, processo de obtenção, processo de detecção, uso de anticorpo, kit e construção gênica |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2016012525A true MX2016012525A (es) | 2017-05-04 |
Family
ID=54193799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016012525A MX2016012525A (es) | 2014-03-27 | 2015-03-27 | Anticuerpo anti-grpr, proceso de obtencion, proceso de deteccion, uso de anticuerpo, kit y construccion genetica. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20170205412A1 (es) |
| EP (1) | EP3124500A4 (es) |
| CN (1) | CN106132993A (es) |
| BR (1) | BR102014007315A2 (es) |
| MX (1) | MX2016012525A (es) |
| WO (1) | WO2015143525A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109422810A (zh) * | 2017-08-24 | 2019-03-05 | 孙立春 | 全人源或人源化bombesin受体GRPR单克隆抗体药物或诊断试剂的开发及应用 |
| CN116333041A (zh) * | 2023-04-10 | 2023-06-27 | 湖南中晟全肽生化有限公司 | 一种激活grp受体的多肽化合物及其用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06509940A (ja) * | 1991-03-15 | 1994-11-10 | バーレックス ラボラトリーズ，インコーポレイティド | ボンベシン様ペプチドに対するレセプター |
| CA2089212C (en) * | 1992-06-12 | 2004-01-20 | Ken Yamaguchi | Antibodies to human gastrin-releasing peptide precusor and use thereof |
| DE69637411T2 (de) * | 1996-06-03 | 2009-01-22 | Advanced Life Science Institute, Inc., Wako | Antikörper gegen den menschlichen gastrinfreisetzenden Peptidvorläufer und deren Verwendung |
| NZ500748A (en) * | 1997-05-12 | 2001-06-29 | Aphton Corp | Methods for the treatment of gastrin-dependent tumours comprising active or passive immunisation with an anti-CCK-B/gastrin receptor immunogen or anti-CCK-B/gastrin receptor antibodies |
| AU2003234623A1 (en) * | 2002-05-16 | 2003-12-02 | Euro-Celtique, S.A. | Use of gastrin releasing peptide (grp) and its receptor in cancer screening |
| US7226577B2 (en) * | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
| US7790407B2 (en) * | 2005-11-29 | 2010-09-07 | Nevada Cancer Institute | Targeting of SALL4 for the treatment and diagnosis of proliferative disorders associated with myelodysplastic syndrome (MDS) |
-
2014
- 2014-03-27 BR BR102014007315A patent/BR102014007315A2/pt not_active Application Discontinuation
-
2015
- 2015-03-27 MX MX2016012525A patent/MX2016012525A/es unknown
- 2015-03-27 CN CN201580016890.8A patent/CN106132993A/zh active Pending
- 2015-03-27 US US15/129,763 patent/US20170205412A1/en not_active Abandoned
- 2015-03-27 WO PCT/BR2015/050034 patent/WO2015143525A1/pt not_active Ceased
- 2015-03-27 EP EP15770271.3A patent/EP3124500A4/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CN106132993A (zh) | 2016-11-16 |
| BR102014007315A2 (pt) | 2016-08-09 |
| WO2015143525A1 (pt) | 2015-10-01 |
| EP3124500A4 (en) | 2017-03-08 |
| US20170205412A1 (en) | 2017-07-20 |
| EP3124500A1 (en) | 2017-02-01 |
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