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MX2016011290A - Composiciones de ester de colina de acido lipoico y metodos de uso. - Google Patents

Composiciones de ester de colina de acido lipoico y metodos de uso.

Info

Publication number
MX2016011290A
MX2016011290A MX2016011290A MX2016011290A MX2016011290A MX 2016011290 A MX2016011290 A MX 2016011290A MX 2016011290 A MX2016011290 A MX 2016011290A MX 2016011290 A MX2016011290 A MX 2016011290A MX 2016011290 A MX2016011290 A MX 2016011290A
Authority
MX
Mexico
Prior art keywords
lipoic acid
choline ester
methods
aqueous
ester compositions
Prior art date
Application number
MX2016011290A
Other languages
English (en)
Other versions
MX384877B (es
Inventor
H Garner William
H Garner Margaret
r burns William
Original Assignee
Encore Vision Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Encore Vision Inc filed Critical Encore Vision Inc
Publication of MX2016011290A publication Critical patent/MX2016011290A/es
Publication of MX384877B publication Critical patent/MX384877B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se relaciona con composiciones farmacéuticas que comprenden una cantidad terapéuticamente efectiva de éster de colina del ácido lipoico o derivados del mismo y un excipiente no acuoso mezclado en una solución acuosa. También se proporcionan en la presente composiciones no acuosas preparadas mezclando la cantidad terapéuticamente efectiva de éster de colina del ácido lipoico y el excipiente no acuoso. Las composiciones no acuosas además pueden mezclarse con la solución acuosa.
MX2016011290A 2014-03-03 2015-03-03 Composiciones de éster de colina de ácido lipoico y métodos de uso. MX384877B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461947378P 2014-03-03 2014-03-03
PCT/US2015/018505 WO2015134510A1 (en) 2014-03-03 2015-03-03 Lipoic acid choline ester compositions and methods of use

Publications (2)

Publication Number Publication Date
MX2016011290A true MX2016011290A (es) 2017-04-27
MX384877B MX384877B (es) 2025-03-14

Family

ID=54055796

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016011290A MX384877B (es) 2014-03-03 2015-03-03 Composiciones de éster de colina de ácido lipoico y métodos de uso.

Country Status (12)

Country Link
US (2) US20160354340A1 (es)
EP (1) EP3113613A4 (es)
JP (1) JP6526066B2 (es)
KR (1) KR20160145558A (es)
CN (2) CN106455563A (es)
AU (2) AU2015227307A1 (es)
BR (1) BR112016020181A8 (es)
CA (1) CA2941518A1 (es)
IL (1) IL247529B (es)
MX (1) MX384877B (es)
RU (1) RU2735790C2 (es)
WO (1) WO2015134510A1 (es)

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JOP20190057A1 (ar) * 2016-09-23 2019-03-24 Encore Vision Inc تركيبات استر كولين حمض الليبويك وطرق تثبيتها إلى منتجات عقار ذات صلة دوائية
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CN106967044B (zh) * 2017-05-12 2019-02-22 苏州富士莱医药股份有限公司 制备r-硫辛酸胆碱酯卤化物的方法
CN107089967A (zh) * 2017-05-12 2017-08-25 苏州富士莱医药股份有限公司 一种r‑硫辛酸胆碱酯卤化物的制备方法
CN109394745A (zh) * 2017-08-17 2019-03-01 博瑞生物医药（苏州）股份有限公司 一种包含左旋肉碱和β-羟基丁酸化合物的组合物
CN113710320A (zh) * 2019-04-17 2021-11-26 参天制药株式会社 硫辛酸前药
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CN113717770B (zh) * 2020-05-25 2022-06-03 中国石油天然气股份有限公司 一种金属加工油
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Also Published As

Publication number Publication date
IL247529A0 (en) 2016-11-30
BR112016020181A2 (pt) 2017-08-15
JP2017511816A (ja) 2017-04-27
EP3113613A4 (en) 2019-03-13
KR20160145558A (ko) 2016-12-20
RU2016137784A (ru) 2018-04-03
JP6526066B2 (ja) 2019-06-05
AU2015227307A1 (en) 2016-10-13
BR112016020181A8 (pt) 2021-06-29
IL247529B (en) 2020-10-29
US11426381B2 (en) 2022-08-30
US20160354340A1 (en) 2016-12-08
CA2941518A1 (en) 2015-09-11
MX384877B (es) 2025-03-14
AU2019240641A1 (en) 2019-10-24
RU2016137784A3 (es) 2018-10-18
EP3113613A1 (en) 2017-01-11
WO2015134510A1 (en) 2015-09-11
AU2019240641B2 (en) 2020-10-29
CN106455563A (zh) 2017-02-22
US20200281891A1 (en) 2020-09-10
RU2735790C2 (ru) 2020-11-09
CN112641720A (zh) 2021-04-13

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