MX2016008594A - Composicion combinada de bromuro de glicopirronio y formoterol en solucion estable presurizada para aerosol. - Google Patents
Composicion combinada de bromuro de glicopirronio y formoterol en solucion estable presurizada para aerosol.Info
- Publication number
- MX2016008594A MX2016008594A MX2016008594A MX2016008594A MX2016008594A MX 2016008594 A MX2016008594 A MX 2016008594A MX 2016008594 A MX2016008594 A MX 2016008594A MX 2016008594 A MX2016008594 A MX 2016008594A MX 2016008594 A MX2016008594 A MX 2016008594A
- Authority
- MX
- Mexico
- Prior art keywords
- glycopyrronium bromide
- aerosol solution
- hydroxy
- salt
- active ingredients
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
- A61M15/0071—Mechanical counters having a display or indicator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
- A61M2039/226—Spindles or actuating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0238—General characteristics of the apparatus characterised by a particular materials the material being a coating or protective layer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Filling Or Discharging Of Gas Storage Vessels (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Abstract
Se describe una composición en solución para aerosol para utilizarse con un inhalador presurizado de dosis medida, que comprende bromuro de glicopirronio y formoterol, o una sal del mismo o un solvato de la sal, opcionalmente en combinación con uno o más ingredientes activos adicionales, estabilizado con una cantidad seleccionada de un ácido mineral y donde la cantidad del producto de degradación N- (3-bromo) - [2-hidroxi -5- [1-hidroxi-2- [1- (4-metoxifenil) propan-2-ilamino]etil]fenil]form amida es menor que el límite de cuantificación, cuando se almacena en condiciones de envejecimiento acelerado a 25°C y 60% de humedad relativa (RH) durante 6 meses en una lata recubierta internamente por una resina que comprende un copolímero de etileno-propileno fluorado (FEP). Los uno o más ingredientes activos opcionales pueden ser corticosteroides para inhalación que se pueden seleccionar entre: dipropionato de beclometasona, budesonida o su 22R-epímero, ciclesonida, flunisolida, propionato de fluticasona, furoato de fluticasona, furoato de mometasona, etc.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13199784 | 2013-12-30 | ||
| PCT/EP2014/079259 WO2015101576A1 (en) | 2013-12-30 | 2014-12-23 | Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016008594A true MX2016008594A (es) | 2016-09-26 |
| MX368835B MX368835B (es) | 2019-10-18 |
Family
ID=49886777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016008594A MX368835B (es) | 2013-12-30 | 2014-12-23 | Composición combinada de bromuro de glicopirronio y formoterol en solución estable presurizada para aerosol. |
Country Status (34)
| Country | Link |
|---|---|
| US (2) | US10596113B2 (es) |
| EP (3) | EP3089735B1 (es) |
| JP (2) | JP6563950B2 (es) |
| KR (2) | KR101861119B1 (es) |
| CN (2) | CN111150728B (es) |
| AR (2) | AR098982A1 (es) |
| AU (1) | AU2014375301B2 (es) |
| BR (1) | BR112016014583B1 (es) |
| CA (1) | CA2935305C (es) |
| CL (1) | CL2016001653A1 (es) |
| CY (1) | CY1120668T1 (es) |
| DK (1) | DK3089735T3 (es) |
| EA (1) | EA033227B1 (es) |
| ES (1) | ES2687345T3 (es) |
| GE (1) | GEP20186855B (es) |
| HR (1) | HRP20181551T1 (es) |
| HU (1) | HUE039513T2 (es) |
| IL (1) | IL246498B (es) |
| LT (1) | LT3089735T (es) |
| MA (1) | MA39155A1 (es) |
| MX (1) | MX368835B (es) |
| MY (1) | MY182861A (es) |
| PE (1) | PE20160997A1 (es) |
| PH (1) | PH12016501268A1 (es) |
| PL (1) | PL3089735T3 (es) |
| PT (1) | PT3089735T (es) |
| RS (1) | RS57687B1 (es) |
| SA (1) | SA516371427B1 (es) |
| SG (1) | SG11201605311UA (es) |
| SI (1) | SI3089735T1 (es) |
| TN (1) | TN2016000261A1 (es) |
| TW (1) | TWI660747B (es) |
| UA (1) | UA117845C2 (es) |
| WO (1) | WO2015101576A1 (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2515855T6 (da) | 2009-12-23 | 2023-06-06 | Chiesi Farm Spa | Kombinationsterapi til COPD |
| PT2515854E (pt) | 2009-12-23 | 2014-05-27 | Chiesi Farma Spa | Formulação de aerossol para dpoc |
| WO2011076841A2 (en) * | 2009-12-23 | 2011-06-30 | Chiesi Farmaceutici S.P.A. | Combination therapy for copd |
| CA2935305C (en) * | 2013-12-30 | 2022-07-12 | Chiesi Farmaceutici S.P.A. | Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination |
| TN2016000262A1 (en) | 2013-12-30 | 2017-10-06 | Chiesi Farm Spa | Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination. |
| EP3383366B2 (en) | 2015-12-04 | 2024-06-05 | Mexichem Fluor S.A. de C.V. | Pharmaceutical composition |
| GB2545025A (en) * | 2015-12-04 | 2017-06-07 | Mexichem Fluor Sa De Cv | Pharmaceutical composition |
| US10098837B2 (en) * | 2016-07-28 | 2018-10-16 | Chiesi Farmaceutici S.P.A. | Combination therapy for COPD |
| PE20191043A1 (es) | 2016-09-19 | 2019-08-06 | Mexichem Fluor Sa De Cv | Composicion farmaceutica |
| CN107233311B (zh) * | 2017-06-27 | 2020-12-04 | 长风药业股份有限公司 | 一种以阿福特罗和格隆溴铵为活性成分的雾化剂及其制备方法 |
| EP3860580A4 (en) * | 2018-10-01 | 2022-07-20 | Kindeva Drug Delivery L.P. | FORMULATION AND AEROSOL CARTRIDGES, INHALATORS AND THE LIKE CONTAINING THE FORMULATION |
| WO2020084549A1 (en) * | 2018-10-25 | 2020-04-30 | Glenmark Specialty S.A. | Nebulization composition comprising glycopyrrolate and formoterol |
| US20220241524A1 (en) * | 2019-07-12 | 2022-08-04 | Kindeva Drug Delivery L.P. | Aerosol formulation, canister, and inhaler containing the formulation, and method of use |
| KR102835735B1 (ko) | 2019-12-02 | 2025-07-21 | 키에시 파르마슈티시 엣스. 피. 에이. | 가압 정량 흡입기를 위한 스테인리스 스틸 캔 |
| PE20221867A1 (es) | 2020-01-28 | 2022-12-02 | Chiesi Farm Spa | Inhaladores de dosis medida presurizada que comprenden una formulacion farmaceutica amortiguada |
| AU2021223587A1 (en) | 2020-02-20 | 2022-09-29 | Chiesi Farmaceutici S.P.A. | Pressurised metered dose inhalers comprising a buffered pharmaceutical formulation |
| CN115989032A (zh) * | 2020-07-31 | 2023-04-18 | 化学研究有限公司 | 用于吸入施用的组合疗法 |
| CN112051346A (zh) * | 2020-09-24 | 2020-12-08 | 珠海瑞思普利生物制药有限公司 | 一种同时测定茚达特罗和格隆溴铵含量的hplc方法 |
| JP2023546025A (ja) | 2020-10-09 | 2023-11-01 | キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ | 加圧定量吸入器のための医薬製剤 |
| WO2023117985A1 (en) * | 2021-12-21 | 2023-06-29 | Chiesi Farmaceutici S.P.A. | Dry powder formulations filled in an inhaler with improved resistance to humidity |
| CN116338014A (zh) * | 2021-12-23 | 2023-06-27 | 上海医药工业研究院有限公司 | 一种吸入用药物组合物的组分分离检测方法 |
| CA3257044A1 (en) | 2022-05-27 | 2023-11-30 | Chiesi Farmaceutici S.P.A. | PHARMACEUTICAL FORMULATION FOR PRESSURIZED DOSING AEROSOL |
| CN119255820A (zh) | 2022-05-27 | 2025-01-03 | 奇斯药制品公司 | 用于加压定量吸入器的药物制剂 |
| CN119630425A (zh) | 2022-05-27 | 2025-03-14 | 奇斯药制品公司 | 用于加压定量吸入器的药物制剂 |
| CN117679423A (zh) | 2022-09-05 | 2024-03-12 | 立生医药(苏州)有限公司 | 预防或治疗呼吸系统疾病的吸入用药物组合物 |
| WO2025179179A1 (en) * | 2024-02-23 | 2025-08-28 | Astrazeneca Ab | Triple combination therapy for copd |
| WO2026006658A1 (en) | 2024-06-27 | 2026-01-02 | Lupin Inc. | Stable pharmaceutical compositions for pressurized metered dose inhalers |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2956062A (en) | 1959-02-26 | 1960-10-11 | Robins Co Inc A H | Esters of amino alcohols |
| DK1102579T3 (da) | 1998-08-04 | 2003-07-14 | Jago Res Ag | Medicinske aerosolformuleringer |
| US20060171899A1 (en) * | 1998-12-10 | 2006-08-03 | Akwete Adjei | Water-stabilized aerosol formulation system and method of making |
| IT1317720B1 (it) | 2000-01-07 | 2003-07-15 | Chiesi Farma Spa | Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani. |
| GB0008660D0 (en) | 2000-04-07 | 2000-05-31 | Arakis Ltd | The treatment of respiratory diseases |
| UA73986C2 (uk) | 2000-05-22 | 2005-10-17 | К'Єзі Фармачеутічі С.П.А. | АЕРОЗОЛЬНА КОМПОЗИЦІЯ, ЩО МІСТИТЬ <font face="Symbol">b</font>2-АДРЕНЕРГІЧНИЙ АГОНІСТ ТРИВАЛОЇ ДІЇ, ДОЗУЮЧИЙ ІНГАЛЯТОР ПІД ТИСКОМ ТА СПОСІБ ЙОГО ЗАПОВНЕННЯ |
| US20060257324A1 (en) | 2000-05-22 | 2006-11-16 | Chiesi Farmaceutici S.P.A. | Pharmaceutical solution formulations for pressurised metered dose inhalers |
| US6750210B2 (en) * | 2000-08-05 | 2004-06-15 | Smithkline Beecham Corporation | Formulation containing novel anti-inflammatory androstane derivative |
| EP1241113A1 (en) * | 2001-03-12 | 2002-09-18 | CHIESI FARMACEUTICI S.p.A. | Inhaler with means for improving chemical stability of medicinal aerosol solution contained therein |
| EP1321159A1 (en) | 2001-12-21 | 2003-06-25 | CHIESI FARMACEUTICI S.p.A. | Pressurized metered dose inhaler (pMDI) actuators with laser drilled orifices |
| US20040126325A1 (en) * | 2002-03-12 | 2004-07-01 | David Lewis | Medicinal aerosol solution formulation products with improved chemical stability |
| DK1713473T3 (da) | 2004-02-06 | 2013-06-17 | Meda Pharma Gmbh & Co Kg | Kombination af anticholinergika og glucocorticoider til langtidsbehandling af astma og COPD |
| CA2550841C (en) | 2004-02-06 | 2012-10-02 | Meda Pharma Gmbh & Co. Kg | Novel combination of anticholinergic and .beta. mimetics for the treatment of respiratory diseases |
| UA88894C2 (ru) * | 2004-02-27 | 2009-12-10 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Стабильные фармацевтические композиции в виде растворов для ингаляторов с дозатором, которые находятся под давлением |
| GB0410399D0 (en) | 2004-05-10 | 2004-06-16 | Arakis Ltd | The treatment of respiratory disease |
| ATE404185T1 (de) * | 2004-05-13 | 2008-08-15 | Chiesi Farma Spa | Medizinische aerosolformulierungen mit verbesserter chemischer stabilität |
| GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
| EP1879620A2 (en) | 2005-03-30 | 2008-01-23 | Schering Corporation | Medicaments and methods combining an anticholinergic, a corticosteroid, and a long acting beta agonist |
| GB0523653D0 (en) | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
| GB0523656D0 (en) | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
| GB0523654D0 (en) | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
| GB0523655D0 (en) | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
| EP2201934A1 (en) * | 2008-12-23 | 2010-06-30 | CHIESI FARMACEUTICI S.p.A. | Tiotropium aerosol formulation products with improved chemical stability |
| CA2764867C (en) * | 2009-06-09 | 2016-05-17 | Elevation Pharmaceuticals, Inc. | Treatment of chronic obstructive pulmonary disease with nebulized beta 2-agonist or combined nebulized beta 2-agonist and anticholinergic administration |
| PT2515854E (pt) | 2009-12-23 | 2014-05-27 | Chiesi Farma Spa | Formulação de aerossol para dpoc |
| WO2011076841A2 (en) * | 2009-12-23 | 2011-06-30 | Chiesi Farmaceutici S.P.A. | Combination therapy for copd |
| DK2515855T6 (da) * | 2009-12-23 | 2023-06-06 | Chiesi Farm Spa | Kombinationsterapi til COPD |
| CN102695496B (zh) | 2009-12-23 | 2014-10-01 | 奇斯药制品公司 | 用于copd的气雾剂制剂 |
| BR112013005283A2 (pt) | 2010-09-06 | 2019-09-24 | Chiesi Farm Spa | atuador de inalador dosimetrado, de inalador dosimetrado e uso de um atuador |
| PH12013502270A1 (en) * | 2011-05-17 | 2014-01-27 | Pearl Therapeutics Inc | Compositions, methods & systems for respiratory delivery of two or more active agents |
| BR112015002757A2 (pt) | 2012-08-29 | 2017-07-04 | Chiesi Farm Spa | acionador para dispositivo inalador de aerossol, objeto em forma cilíndrica oca, inalador, acionador de inalador dosimétrico, kit e uso de um acionador |
| TN2016000262A1 (en) * | 2013-12-30 | 2017-10-06 | Chiesi Farm Spa | Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination. |
| CA2935305C (en) * | 2013-12-30 | 2022-07-12 | Chiesi Farmaceutici S.P.A. | Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination |
-
2014
- 2014-12-23 CA CA2935305A patent/CA2935305C/en active Active
- 2014-12-23 PT PT14825154T patent/PT3089735T/pt unknown
- 2014-12-23 MY MYPI2016001207A patent/MY182861A/en unknown
- 2014-12-23 BR BR112016014583-6A patent/BR112016014583B1/pt active IP Right Grant
- 2014-12-23 PL PL14825154T patent/PL3089735T3/pl unknown
- 2014-12-23 WO PCT/EP2014/079259 patent/WO2015101576A1/en not_active Ceased
- 2014-12-23 KR KR1020187007444A patent/KR101861119B1/ko active Active
- 2014-12-23 PE PE2016000968A patent/PE20160997A1/es unknown
- 2014-12-23 EA EA201691126A patent/EA033227B1/ru active Protection Beyond IP Right Term
- 2014-12-23 MX MX2016008594A patent/MX368835B/es active IP Right Grant
- 2014-12-23 HU HUE14825154A patent/HUE039513T2/hu unknown
- 2014-12-23 EP EP14825154.9A patent/EP3089735B1/en active Active
- 2014-12-23 AU AU2014375301A patent/AU2014375301B2/en active Active
- 2014-12-23 CN CN202010180583.6A patent/CN111150728B/zh active Active
- 2014-12-23 EP EP19175726.9A patent/EP3566694A1/en active Pending
- 2014-12-23 EP EP18171127.6A patent/EP3384898A1/en active Pending
- 2014-12-23 CN CN201480071526.7A patent/CN105848641B/zh active Active
- 2014-12-23 SG SG11201605311UA patent/SG11201605311UA/en unknown
- 2014-12-23 SI SI201430881T patent/SI3089735T1/sl unknown
- 2014-12-23 ES ES14825154.9T patent/ES2687345T3/es active Active
- 2014-12-23 RS RS20181112A patent/RS57687B1/sr unknown
- 2014-12-23 UA UAA201606910A patent/UA117845C2/uk unknown
- 2014-12-23 JP JP2016561079A patent/JP6563950B2/ja active Active
- 2014-12-23 DK DK14825154.9T patent/DK3089735T3/en active
- 2014-12-23 LT LTEP14825154.9T patent/LT3089735T/lt unknown
- 2014-12-23 GE GEAP201814191A patent/GEP20186855B/en unknown
- 2014-12-23 HR HRP20181551TT patent/HRP20181551T1/hr unknown
- 2014-12-23 TN TN2016000261A patent/TN2016000261A1/en unknown
- 2014-12-23 KR KR1020167020695A patent/KR101861117B1/ko active Active
- 2014-12-29 TW TW103146043A patent/TWI660747B/zh active
- 2014-12-29 AR ARP140104938A patent/AR098982A1/es not_active Application Discontinuation
- 2014-12-30 US US14/585,533 patent/US10596113B2/en active Active
-
2016
- 2016-06-28 MA MA39155A patent/MA39155A1/fr unknown
- 2016-06-28 PH PH12016501268A patent/PH12016501268A1/en unknown
- 2016-06-28 CL CL2016001653A patent/CL2016001653A1/es unknown
- 2016-06-28 SA SA516371427A patent/SA516371427B1/ar unknown
- 2016-06-28 IL IL246498A patent/IL246498B/en active IP Right Grant
- 2016-06-29 US US15/196,318 patent/US10617638B2/en active Active
-
2018
- 2018-09-11 CY CY181100949T patent/CY1120668T1/el unknown
-
2019
- 2019-07-25 JP JP2019136785A patent/JP6823118B2/ja active Active
-
2023
- 2023-08-17 AR ARP230102185A patent/AR130239A2/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2016008594A (es) | Composicion combinada de bromuro de glicopirronio y formoterol en solucion estable presurizada para aerosol. | |
| MX2016008591A (es) | Composicion combinada de bromuro de glicopirronio y formoterol en solucion estable presurizada para aerosol. | |
| BR112022014228A2 (pt) | Inaladores pressurizados de dose calibrada compreendendo uma formulação farmacêutica tamponada | |
| AR081540A1 (es) | Proceso para proveer particulas con cargas electroestaticas reducidas | |
| MX2021009476A (es) | Composiciones farmacéuticas que comprenden sales de glicopirrolato y 1,1-difluoroetano. | |
| EA201290375A1 (ru) | Комбинированная терапия copd | |
| CO2022012207A2 (es) | Inhaladores de dosis medida presurizada que comprenden una formulación farmacéutica amortiguada | |
| MX2015015132A (es) | Composiciones farmaceuticas inhalables y los dispositivos inhaladores que las contienen. | |
| CO2022007719A2 (es) | Lata de acero inoxidable para inhaladores dosificadores presurizados | |
| TH171992A (th) | องค์ประกอบสารละลายชนิดละอองลอยแบบอัดความดันที่เสถียรของการรวมกันของ ไกลโคไพร์โรเนียมโบรไมด์ และฟอร์โมเทอรอล | |
| TH171993A (th) | องค์ประกอบสารละลายชนิดละอองลอยแบบอัดความดันที่เสถียรของการรวมกันของ ไกลโคไพร์โรเนียมโบรไมด์ และฟอร์โมเทอรอล | |
| ZA202108150B (en) | An inhalable fixed dose powder composition comprising glycopyrronium, formoterol and fluticasone propionate | |
| AR085443A1 (es) | Formulaciones medicinales en aerosol que no dañan la capa de ozono y con bajo efecto invernadero | |
| TR201714893A1 (tr) | Beta-2 Agonisti ve Kortikosteroid içeren kuru toz bileşimi. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |