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MX2016008305A - Combinaciones de peptidos y usos de los mismos en tratar alergia al acaro del polvo. - Google Patents

Combinaciones de peptidos y usos de los mismos en tratar alergia al acaro del polvo.

Info

Publication number
MX2016008305A
MX2016008305A MX2016008305A MX2016008305A MX2016008305A MX 2016008305 A MX2016008305 A MX 2016008305A MX 2016008305 A MX2016008305 A MX 2016008305A MX 2016008305 A MX2016008305 A MX 2016008305A MX 2016008305 A MX2016008305 A MX 2016008305A
Authority
MX
Mexico
Prior art keywords
dust mite
der
peptide combinations
peptides
mite allergy
Prior art date
Application number
MX2016008305A
Other languages
English (en)
Inventor
Sette Alessandro
Lundegaard Claus
Harder CHRISTENSEN Lars
Adler WÜRTZEN Peter
Sidney John
Lund Gitte
Original Assignee
Alk-Abelló As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alk-Abelló As filed Critical Alk-Abelló As
Publication of MX2016008305A publication Critical patent/MX2016008305A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención se relaciona a combinaciones de péptidos o variantes de los mismos derivados de una porción de una secuencia de amino de un alérgeno de ácaro del polvo doméstico, por ejemplo los alérgenos Der p 1, Der f 1, Der p 2 y/o Der f 2. Tales péptidos comprenden al menos un epítopo de célula T y un número elevado significativo de pacientes en una población mundial tendrán alelos HLA con el potencial de ligar los péptidos de las combinaciones de péptidos. La invención también se relaciona al uso de tales combinaciones de péptidos en aliviar una respuesta inmunitaria causada por un ácaro del polvo.
MX2016008305A 2013-12-23 2014-12-23 Combinaciones de peptidos y usos de los mismos en tratar alergia al acaro del polvo. MX2016008305A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361919925P 2013-12-23 2013-12-23
US201462012690P 2014-06-16 2014-06-16
PCT/US2014/072228 WO2015100360A1 (en) 2013-12-23 2014-12-23 Peptide combinations and uses thereof in treating dust mite allergy

Publications (1)

Publication Number Publication Date
MX2016008305A true MX2016008305A (es) 2017-01-11

Family

ID=52293308

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016008305A MX2016008305A (es) 2013-12-23 2014-12-23 Combinaciones de peptidos y usos de los mismos en tratar alergia al acaro del polvo.

Country Status (12)

Country Link
US (1) US10059751B2 (es)
EP (1) EP3086806B1 (es)
JP (1) JP2017507906A (es)
KR (1) KR20160096206A (es)
CN (1) CN105848677B (es)
AU (1) AU2014369866A1 (es)
BR (1) BR112016011930A2 (es)
CA (1) CA2933552A1 (es)
EA (1) EA201691306A1 (es)
MX (1) MX2016008305A (es)
SG (1) SG11201604892YA (es)
WO (1) WO2015100360A1 (es)

Families Citing this family (11)

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AU2011260233C1 (en) * 2010-06-03 2015-04-16 Alk-Abello A/S Pharmaceutical product comprising mite allergen extract(s) and a method for the manufacture thereof
US11013781B2 (en) 2015-07-01 2021-05-25 Alk-Abelló As Peptide combinations and uses thereof for treating grass allergy
EP3383427A4 (en) * 2015-12-04 2019-11-27 Mayo Foundation for Medical Education and Research METHOD AND VACCINES FOR INDUCTION OF IMMUNE REACTIONS TO SEVERAL DIFFERENT MHC MOLECULES
US10556936B2 (en) 2016-05-27 2020-02-11 Alk Abelló Immunogenic proteins and fragments thereof from allergenic mites
CN108265059B (zh) 2016-12-31 2021-01-05 江苏众红生物工程创药研究院有限公司 一种重组粉尘螨2类变应原蛋白及其制备方法与应用
CN107338261B (zh) * 2017-07-17 2023-04-07 海南大学 热带无爪螨重组变应原Blot5-21、其制备方法及过敏小鼠模型的建立
CN119367552A (zh) * 2019-03-14 2025-01-28 恩根尼公司 壳聚糖-核酸纳米颗粒的可逆包衣以及其使用方法
CN113125753B (zh) * 2021-04-16 2022-07-26 杭州浙大迪迅生物基因工程有限公司 一种用于检测尘螨组分特异性抗体的试剂盒
KR20240140698A (ko) 2023-03-17 2024-09-24 가톨릭대학교 산학협력단 집먼지진드기 항원 및 히알루론산 하이드로젤을 유효성분으로 포함하는 알레르기 질환 면역 치료용 조성물
GB202409214D0 (en) * 2024-06-26 2024-08-07 Univ Birmingham tolerogenic peptides
CN120559260A (zh) * 2025-07-30 2025-08-29 无锡市人民医院 过敏原Blo t 24在尘螨过敏原组分检测中的应用

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AU682658B2 (en) 1991-10-16 1997-10-16 Merck Patent Gmbh Recombitope peptides
WO1994024281A1 (en) 1993-04-14 1994-10-27 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
US7288256B1 (en) * 1991-10-16 2007-10-30 Merck Patent Gmbh T cell epitopes of the major allergens from dermatophagoides (house dust mite)
US5820862A (en) * 1994-04-14 1998-10-13 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
AU717187B2 (en) 1994-04-14 2000-03-16 Merck Patent Gmbh Pharmaceutical peptide formulations for treatment of dust mite allergy
JP2001231563A (ja) * 2000-02-18 2001-08-28 Asahi Breweries Ltd 改変したダニアレルゲン（システイン変異体）及びその製造方法
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JP2010512170A (ja) 2005-12-08 2010-04-22 ナノパス テクノロジーズ エルティディ． 薬剤投与器用マイクロ・ニードル・アダプタ
PL2059256T3 (pl) * 2006-08-11 2017-02-28 Life Sciences Research Partners Vzw Immunogenne peptydy i ich zastosowanie w zaburzeniach immunologicznych
EP2083856B1 (en) * 2007-08-15 2010-09-29 Circassia Limited Peptides for desensibilization against allergens
JP5705113B2 (ja) 2008-08-15 2015-04-22 サーカッシア リミテッド Ｉｌ−１０産生の刺激のためのアレルゲン由来のｔ細胞抗原
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US20140350514A1 (en) 2013-05-22 2014-11-27 Nanopass Technologies Ltd. Systems and methods for intradermal delivery of therapeutics using microneedles

Also Published As

Publication number Publication date
BR112016011930A2 (pt) 2017-09-26
CA2933552A1 (en) 2015-07-02
AU2014369866A1 (en) 2016-06-30
EP3086806A1 (en) 2016-11-02
EA201691306A1 (ru) 2016-10-31
WO2015100360A1 (en) 2015-07-02
US20160251403A1 (en) 2016-09-01
KR20160096206A (ko) 2016-08-12
EP3086806B1 (en) 2019-12-11
US10059751B2 (en) 2018-08-28
CN105848677A (zh) 2016-08-10
CN105848677B (zh) 2020-01-31
JP2017507906A (ja) 2017-03-23
SG11201604892YA (en) 2016-07-28

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