MX2016007057A - Administracion y monitoreo de oxido nitrico en fluidos ex vivo. - Google Patents
Administracion y monitoreo de oxido nitrico en fluidos ex vivo.Info
- Publication number
- MX2016007057A MX2016007057A MX2016007057A MX2016007057A MX2016007057A MX 2016007057 A MX2016007057 A MX 2016007057A MX 2016007057 A MX2016007057 A MX 2016007057A MX 2016007057 A MX2016007057 A MX 2016007057A MX 2016007057 A MX2016007057 A MX 2016007057A
- Authority
- MX
- Mexico
- Prior art keywords
- nitric oxide
- administration
- monitoring
- fluids
- fluid
- Prior art date
Links
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title abstract 14
- 238000012544 monitoring process Methods 0.000 title abstract 2
- 239000012530 fluid Substances 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000002618 extracorporeal membrane oxygenation Methods 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 230000010412 perfusion Effects 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
- A01N1/142—Apparatus
- A01N1/143—Apparatus for organ perfusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3623—Means for actively controlling temperature of blood
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0641—Erythrocytes
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Anesthesiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- External Artificial Organs (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
La presente invención se refiere a sistemas y métodos para monitorear la administración de óxido nítrico (NO) a fluidos ex vivo. Ejemplos de tales fluidos incluyen sangre en los circuitos de oxigenación de membrana extracorporal (ECMO) o fluidos de perfusión usados para preservar órganos ex vivo previo al transplante en un recipiente. Los sistemas y métodos descritos en la presente se proporcionan para administrar óxido nítrico al fluido, monitorear óxido nítrico o un marcador de óxido nítrico en el fluido, y ajustar la administración de óxido nítrico.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361787865P | 2013-03-15 | 2013-03-15 | |
| US14/095,621 US9629358B2 (en) | 2013-03-15 | 2013-12-03 | Administration and monitoring of nitric oxide in ex vivo fluids |
| PCT/US2014/067856 WO2015084698A2 (en) | 2013-03-15 | 2014-12-01 | Administration and monitoring of nitric oxide in ex vivo fluids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016007057A true MX2016007057A (es) | 2017-02-02 |
| MX381625B MX381625B (es) | 2025-03-12 |
Family
ID=51528684
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016007057A MX381625B (es) | 2013-03-15 | 2014-12-01 | Administración y monitoreo de óxido nítrico en fluidos ex vivo. |
| MX2021001867A MX2021001867A (es) | 2013-03-15 | 2016-05-31 | Administracion y monitoreo de oxidio nitrico en fluidos ex vivo. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021001867A MX2021001867A (es) | 2013-03-15 | 2016-05-31 | Administracion y monitoreo de oxidio nitrico en fluidos ex vivo. |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9629358B2 (es) |
| EP (2) | EP3086638B1 (es) |
| JP (2) | JP6612231B2 (es) |
| AU (3) | AU2014357412B2 (es) |
| CA (3) | CA3135254C (es) |
| DK (1) | DK3698630T3 (es) |
| ES (1) | ES2805366T3 (es) |
| FI (1) | FI3698630T3 (es) |
| MX (2) | MX381625B (es) |
| PL (1) | PL3698630T3 (es) |
| PT (1) | PT3698630T (es) |
| WO (1) | WO2015084698A2 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ554543A (en) | 2004-10-07 | 2011-03-31 | Transmedics Inc | Systems for ex-vivo organ care |
| US12010987B2 (en) | 2004-10-07 | 2024-06-18 | Transmedics, Inc. | Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status |
| US9078428B2 (en) | 2005-06-28 | 2015-07-14 | Transmedics, Inc. | Systems, methods, compositions and solutions for perfusing an organ |
| US9457179B2 (en) | 2007-03-20 | 2016-10-04 | Transmedics, Inc. | Systems for monitoring and applying electrical currents in an organ perfusion system |
| US8420380B2 (en) | 2008-01-31 | 2013-04-16 | Transmedics, Inc. | Systems and methods for ex vivo lung care |
| CN109997836B (zh) | 2011-04-14 | 2022-02-08 | 特兰斯迈迪茨公司 | 用于供体肺的离体机器灌注的器官护理溶液 |
| JP2017518301A (ja) | 2014-06-02 | 2017-07-06 | トランスメディクス, インク.Transmedics, Inc. | ex−vivoでの臓器管理システム |
| US11083191B2 (en) | 2014-12-12 | 2021-08-10 | Tevosol, Inc. | Apparatus and method for organ perfusion |
| JP6934005B2 (ja) | 2015-09-09 | 2021-09-08 | トランスメディクス,インコーポレイテッド | エキソビボ臓器管理システムのための大動脈カニューレ |
| EP3386574A4 (en) * | 2015-12-11 | 2019-07-17 | Vero Biotech LLC | METHOD AND APPARATUS FOR GAS ADMINISTRATION COMPRISING NITRIC OXIDE FOR TREATING FIBROSIS |
| AU2017218391B2 (en) | 2016-02-12 | 2022-11-24 | Mallinckrodt Pharmaceuticals Ireland Limited | Use and monitoring of inhaled nitric oxide with left ventricular assist devices |
| DK3462861T5 (da) | 2016-05-30 | 2024-01-08 | Transmedics Inc | Fremgangsmåde til ex vivo-lungeventilati on med et varierende udvendigt tryk |
| EP3509684A4 (en) * | 2016-09-10 | 2020-10-21 | Vero Biotech LLC | PORTABLE NITRIC OXIDE ADMINISTRATION SYSTEM AND METHOD |
| TWI656890B (zh) * | 2017-07-12 | 2019-04-21 | 英屬開曼群島商怡忠國際有限公司 | 體外生命支持系統 |
| AU2018322317B2 (en) * | 2017-08-25 | 2023-11-23 | Mallinckrodt Pharmaceuticals Ireland Limited | Methods to improve organ viability |
| US11881119B2 (en) * | 2017-12-06 | 2024-01-23 | Cilag Gmbh International | Modeling air leaks in lungs |
| GB2587350B (en) * | 2019-09-23 | 2021-12-15 | Royal Papworth Hospital Nhs Found Trust | Organ perfusion system and method |
| WO2021177164A1 (ja) * | 2020-03-05 | 2021-09-10 | テルモ株式会社 | 医療デバイス |
| GB2596041B (en) * | 2020-03-26 | 2024-12-04 | Univ Newcastle | System and Method for Monitoring Body Tissue |
| CN113797404B (zh) * | 2021-01-06 | 2023-05-09 | 郝云玲 | 一种向血液中补充一氧化氮(no)的装置 |
| EP4137170A1 (en) | 2021-07-29 | 2023-02-22 | Tim Bast | Purge fluid generator for membrane oxygenation |
| CN113975505B (zh) * | 2021-11-08 | 2023-12-19 | 中山大学中山眼科中心 | 用于眼球灌注的体外循环系统 |
| US12128166B2 (en) | 2022-12-16 | 2024-10-29 | Fresenius Medical Care Holdings, Inc. | Systems and methods for using nitric oxide in dialysis |
| US12357533B2 (en) * | 2023-08-25 | 2025-07-15 | Paragonix Technologies, Inc. | Systems and methods for maintaining organ pressure |
| WO2025213152A1 (en) * | 2024-04-06 | 2025-10-09 | The Board Of Trustees Of The Leland Stanford Junior University | Cardiac ex vivo preservation system compatible for use with any oxygenator and pump |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5338662A (en) | 1992-09-21 | 1994-08-16 | Bio-Preserve Medical Corporation | Organ perfusion device |
| US5558083A (en) | 1993-11-22 | 1996-09-24 | Ohmeda Inc. | Nitric oxide delivery system |
| US5725492A (en) * | 1996-03-04 | 1998-03-10 | Cormedics Corp | Extracorporeal circulation apparatus and method |
| EP1712226A3 (en) * | 1996-04-05 | 2007-03-21 | The General Hospital Corporation | Treatment of a Hemoglobinopathy |
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| US5752504A (en) | 1996-12-13 | 1998-05-19 | Ohmeda Inc. | System for monitoring therapy during calibration |
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| US7749693B2 (en) * | 1998-09-29 | 2010-07-06 | Lifeline Scientific, Inc. | Method of determining that an organ is not suitable for transplantation and using it for testing substances |
| GB9908335D0 (en) * | 1999-04-12 | 1999-06-09 | Univ Cambridge Tech | Methods and means for extracorporeal organ perfusion |
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| JP4352315B2 (ja) * | 2002-10-31 | 2009-10-28 | 日本光電工業株式会社 | 信号処理方法/装置及びそれを用いたパルスフォトメータ |
| US7485324B2 (en) * | 2003-09-29 | 2009-02-03 | Pulmonox Technologies Corporation | Use of exogenous gaseous nitric oxide in the treatment and disinfection of biofilms |
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| US7523752B2 (en) | 2005-09-21 | 2009-04-28 | Ino Therapeutics, Llc | System and method of administering a pharmaceutical gas to a patient |
| WO2007124044A2 (en) | 2006-04-19 | 2007-11-01 | Transmedics, Inc. | Systems and methods for ex vivo organ care |
| US8420380B2 (en) * | 2008-01-31 | 2013-04-16 | Transmedics, Inc. | Systems and methods for ex vivo lung care |
| WO2010076737A1 (en) * | 2008-12-31 | 2010-07-08 | Koninklijke Philips Electronics N.V. | A method and apparatus for controlling a process of injury therapy |
| US9216198B2 (en) | 2009-03-30 | 2015-12-22 | The Board Of Regents, The University Of Texas System | Compositions and medical devices for controlled release of nitric oxide and methods of production thereof |
| CA2671029A1 (en) | 2009-06-30 | 2010-12-30 | James S. Baldassarre | Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension |
| US20120201906A1 (en) | 2009-09-08 | 2012-08-09 | Reynolds James D | Novel medical uses for no and no donor compounds |
| MX378823B (es) | 2011-01-06 | 2025-03-10 | Mallinckrodt Hospital Products Ip Ltd | Dispositivo y sistema de entrega de gas. |
| CA2854776C (en) | 2011-11-07 | 2020-08-18 | Ino Therapeutics Llc | Apparatus and method for monitoring nitric oxide delivery |
| WO2013181322A1 (en) * | 2012-05-31 | 2013-12-05 | Ino Therapeutics Llc | Methods of administering nitric oxide to arterial or arterialized blood |
| MX375330B (es) * | 2013-03-13 | 2025-03-06 | Mallinckrodt Hospital Products Ip Ltd | Dispositivos y metodos para monitorizar la oxigenacion durante el tratamiento con el suminitro de oxido nitrico. |
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2013
- 2013-12-03 US US14/095,621 patent/US9629358B2/en active Active
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2014
- 2014-12-01 US US14/556,364 patent/US20150093738A1/en not_active Abandoned
- 2014-12-01 JP JP2016536173A patent/JP6612231B2/ja active Active
- 2014-12-01 FI FIEP20169811.5T patent/FI3698630T3/fi active
- 2014-12-01 CA CA3135254A patent/CA3135254C/en active Active
- 2014-12-01 EP EP14824182.1A patent/EP3086638B1/en active Active
- 2014-12-01 DK DK20169811.5T patent/DK3698630T3/da active
- 2014-12-01 PT PT201698115T patent/PT3698630T/pt unknown
- 2014-12-01 ES ES14824182T patent/ES2805366T3/es active Active
- 2014-12-01 CA CA2931943A patent/CA2931943C/en active Active
- 2014-12-01 AU AU2014357412A patent/AU2014357412B2/en active Active
- 2014-12-01 MX MX2016007057A patent/MX381625B/es unknown
- 2014-12-01 PL PL20169811.5T patent/PL3698630T3/pl unknown
- 2014-12-01 WO PCT/US2014/067856 patent/WO2015084698A2/en not_active Ceased
- 2014-12-01 EP EP20169811.5A patent/EP3698630B1/en active Active
- 2014-12-01 CA CA3233961A patent/CA3233961A1/en active Pending
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2016
- 2016-05-31 MX MX2021001867A patent/MX2021001867A/es unknown
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2017
- 2017-04-21 US US15/493,578 patent/US11291202B2/en active Active
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2018
- 2018-05-23 AU AU2018203630A patent/AU2018203630B2/en active Active
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2019
- 2019-10-10 AU AU2019246828A patent/AU2019246828B2/en active Active
- 2019-10-30 JP JP2019196848A patent/JP6884190B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| PT3698630T (pt) | 2024-05-31 |
| EP3698630A1 (en) | 2020-08-26 |
| CA2931943C (en) | 2021-11-30 |
| ES2805366T3 (es) | 2021-02-11 |
| FI3698630T3 (fi) | 2024-05-24 |
| JP6884190B2 (ja) | 2021-06-09 |
| PL3698630T3 (pl) | 2024-08-05 |
| US20170215411A1 (en) | 2017-08-03 |
| EP3086638B1 (en) | 2020-04-22 |
| CA2931943A1 (en) | 2015-06-11 |
| MX2021001867A (es) | 2021-04-19 |
| US20140272920A1 (en) | 2014-09-18 |
| DK3698630T3 (da) | 2024-05-21 |
| EP3086638A2 (en) | 2016-11-02 |
| US20150093738A1 (en) | 2015-04-02 |
| JP6612231B2 (ja) | 2019-11-27 |
| EP3698630B1 (en) | 2024-03-13 |
| AU2014357412B2 (en) | 2018-03-01 |
| AU2018203630B2 (en) | 2019-08-29 |
| JP2020033368A (ja) | 2020-03-05 |
| AU2018203630A1 (en) | 2018-06-21 |
| CA3135254A1 (en) | 2015-06-11 |
| AU2019246828B2 (en) | 2021-12-02 |
| US11291202B2 (en) | 2022-04-05 |
| AU2014357412A1 (en) | 2016-06-16 |
| JP2017503762A (ja) | 2017-02-02 |
| WO2015084698A3 (en) | 2015-11-05 |
| MX381625B (es) | 2025-03-12 |
| AU2019246828A1 (en) | 2019-11-07 |
| US9629358B2 (en) | 2017-04-25 |
| WO2015084698A2 (en) | 2015-06-11 |
| CA3135254C (en) | 2024-05-14 |
| CA3233961A1 (en) | 2015-06-11 |
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