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MX2016006571A - Aparatos y metodos de seleccion de anticuerpo. - Google Patents

Aparatos y metodos de seleccion de anticuerpo.

Info

Publication number
MX2016006571A
MX2016006571A MX2016006571A MX2016006571A MX2016006571A MX 2016006571 A MX2016006571 A MX 2016006571A MX 2016006571 A MX2016006571 A MX 2016006571A MX 2016006571 A MX2016006571 A MX 2016006571A MX 2016006571 A MX2016006571 A MX 2016006571A
Authority
MX
Mexico
Prior art keywords
methods
antibody
selection apparatus
antibody selection
articles
Prior art date
Application number
MX2016006571A
Other languages
English (en)
Other versions
MX385775B (es
Inventor
Vikas K Sharma
E Swartz Trevor
W Patapoff Thomas
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2016006571A publication Critical patent/MX2016006571A/es
Publication of MX385775B publication Critical patent/MX385775B/es

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/50—Molecular design, e.g. of drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G16B35/20—Screening of libraries
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C10/00—Computational theoretical chemistry, i.e. ICT specially adapted for theoretical aspects of quantum chemistry, molecular mechanics, molecular dynamics or the like
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60—In silico combinatorial chemistry
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Molecular Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Library & Information Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Computing Systems (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Aparatos, sistemas, medios legibles por computadora, artículos de manufactura y métodos para seleccionar un anticuerpo. Aparatos, sistemas, medios legibles por computadora, artículos de manufactura y métodos para producir el anticuerpo seleccionado. La selección puede incluir determinar una o más características fisicoquímicas del anticuerpo. La determinación puede basarse en parámetros estructurales del anticuerpo.
MX2016006571A 2013-11-29 2014-11-26 Aparatos y métodos de selección de anticuerpo. MX385775B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361910200P 2013-11-29 2013-11-29
PCT/US2014/067580 WO2015081176A2 (en) 2013-11-29 2014-11-26 Antibody selection apparatus and methods

Publications (2)

Publication Number Publication Date
MX2016006571A true MX2016006571A (es) 2016-08-05
MX385775B MX385775B (es) 2025-03-18

Family

ID=52273498

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016006571A MX385775B (es) 2013-11-29 2014-11-26 Aparatos y métodos de selección de anticuerpo.

Country Status (10)

Country Link
US (3) US10861584B2 (es)
EP (1) EP3074772B1 (es)
JP (2) JP7156777B2 (es)
KR (1) KR102362002B1 (es)
CN (2) CN105793850B (es)
BR (1) BR112016009862B1 (es)
CA (1) CA2924448C (es)
MX (1) MX385775B (es)
RU (1) RU2742070C2 (es)
WO (1) WO2015081176A2 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016009862B1 (pt) 2013-11-29 2021-12-21 Genentech, Inc Método de fabricação de uma composição
ES2814287T3 (es) * 2016-03-15 2021-03-26 Amgen Inc Reducir la probabilidad de rotura de cristal en dispositivos de administración de fármaco
CN114503204A (zh) * 2019-08-02 2022-05-13 豪夫迈·罗氏有限公司 抗体静电学的基于多极矩的粗粒度表示
AU2020332821A1 (en) * 2019-08-20 2022-03-10 Regeneron Pharmaceuticals, Inc. Formulation optimization for bispecific antibodies
AU2020355405A1 (en) * 2019-09-25 2022-05-19 Janssen Pharmaceuticals, Inc. Remote aggregation of data for drug administration devices
EP4435794A3 (en) * 2020-11-02 2024-12-18 Regeneron Pharmaceuticals, Inc. Methods and systems for biotherapeutic development
CN112986206B (zh) * 2021-05-20 2021-07-30 北京百奥纳芯生物科技有限公司 一种检测基因芯片杂交结果的方法
WO2023107580A1 (en) * 2021-12-08 2023-06-15 The Johns Hopkins University Generative language models and related aspects for peptide and protein sequence design
EP4526882A1 (en) * 2022-05-18 2025-03-26 Sanofi Method, system and apparatus for predicting pk values of antibodies
CN119032398B (zh) * 2023-04-04 2025-09-23 南京金斯瑞生物科技有限公司 用于抗体药物开发的黏度预测方法
CN121039495A (zh) * 2023-05-05 2025-11-28 豪夫迈·罗氏有限公司 用于自动化样品制备和在线肽图谱分析的多级设备

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6172213B1 (en) * 1997-07-02 2001-01-09 Genentech, Inc. Anti-IgE antibodies and method of improving polypeptides
AU2003291689A1 (en) * 2002-10-31 2004-05-25 Protein Design Labs, Inc. Stable liquid pharmaceutical formulation of antibodies that are prone to isomerization
ME00226B (me) * 2004-07-15 2011-02-10 Medarex Llc Humana anti-ngf neutrališuća antitijela kao selektivni inhibitori ngf signalne kaskade
CN101023101A (zh) * 2004-07-20 2007-08-22 西福根有限公司 抗－恒河猴d重组多克隆抗体和生产方法
EP1848745B1 (en) * 2005-02-18 2014-07-09 Medarex, L.L.C. Monoclonal antibodies against cd30 lacking in fucosyl residues
IN2014DN10515A (es) * 2006-03-31 2015-08-21 Chugai Pharmaceutical Co Ltd
BRPI0814252B8 (pt) * 2007-06-14 2021-05-25 Biogen Idec Inc composição farmacêutica aquosa estável compreendendo natalizumabe, dose unitária, e seringa pré-cheia
JP5334319B2 (ja) * 2007-09-26 2013-11-06 中外製薬株式会社 Ｃｄｒのアミノ酸置換により抗体の等電点を改変する方法
KR20100085067A (ko) * 2007-09-28 2010-07-28 추가이 세이야쿠 가부시키가이샤 혈장 중 반응속도가 개선된 항-글리피칸-3 항체
BR112012002596A2 (pt) * 2009-08-04 2015-09-15 Genentech Inc formulações de polipeptídeo concentradas com viscodidade reduzida
AR080685A1 (es) * 2010-03-17 2012-05-02 Abbott Res Bv Composiciones de anticuerpos anti-factor de crecimiento nervioso (ngf)
WO2013063510A1 (en) * 2011-10-28 2013-05-02 Integritybio Inc. Protein formulations containing amino acids
JP6294311B2 (ja) * 2012-05-23 2018-03-14 ジェネンテック， インコーポレイテッド 治療薬の選択方法
WO2014186692A1 (en) * 2013-05-17 2014-11-20 Massachusetts Institute Of Technology Computer-implemented methods of determining protein viscosity
BR112016009862B1 (pt) 2013-11-29 2021-12-21 Genentech, Inc Método de fabricação de uma composição

Also Published As

Publication number Publication date
US20210065843A1 (en) 2021-03-04
CN111402950B (zh) 2024-03-19
CN105793850A (zh) 2016-07-20
US20260004872A1 (en) 2026-01-01
KR20160088318A (ko) 2016-07-25
CN111402950A (zh) 2020-07-10
US12444477B2 (en) 2025-10-14
RU2016119424A (ru) 2018-01-09
CA2924448A1 (en) 2015-06-04
EP3074772B1 (en) 2025-06-04
WO2015081176A2 (en) 2015-06-04
WO2015081176A3 (en) 2015-10-08
BR112016009862B1 (pt) 2021-12-21
KR102362002B1 (ko) 2022-02-10
JP7481844B2 (ja) 2024-05-13
CA2924448C (en) 2021-12-14
EP3074772C0 (en) 2025-06-04
US10861584B2 (en) 2020-12-08
JP2020090504A (ja) 2020-06-11
BR112016009862A2 (pt) 2017-08-01
JP2017512750A (ja) 2017-05-25
EP3074772A2 (en) 2016-10-05
US20170091377A1 (en) 2017-03-30
JP7156777B2 (ja) 2022-10-19
RU2742070C2 (ru) 2021-02-02
CN105793850B (zh) 2020-04-24
MX385775B (es) 2025-03-18

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