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MX2016000272A - Construcciones de unión a los antígenos cd19 y cd3 biespecificos. - Google Patents

Construcciones de unión a los antígenos cd19 y cd3 biespecificos.

Info

Publication number
MX2016000272A
MX2016000272A MX2016000272A MX2016000272A MX2016000272A MX 2016000272 A MX2016000272 A MX 2016000272A MX 2016000272 A MX2016000272 A MX 2016000272A MX 2016000272 A MX2016000272 A MX 2016000272A MX 2016000272 A MX2016000272 A MX 2016000272A
Authority
MX
Mexico
Prior art keywords
contructs
antigen binding
bispecific
antigens
bind
Prior art date
Application number
MX2016000272A
Other languages
English (en)
Inventor
Bhimarao Dixit Surjit
Yiu Kon Ng Gordon
Spreter Von Kreudenstein Thomas
Original Assignee
Zymeworks Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymeworks Inc filed Critical Zymeworks Inc
Publication of MX2016000272A publication Critical patent/MX2016000272A/es

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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • C—CHEMISTRY; METALLURGY
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  • Hematology (AREA)
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Abstract

Se describen construcciones de unión a antígenos biespecíficos, que se unen a antígenos CD3 y CD19 o CD20.
MX2016000272A 2013-07-12 2014-07-11 Construcciones de unión a los antígenos cd19 y cd3 biespecificos. MX2016000272A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361845948P 2013-07-12 2013-07-12
US201461927877P 2014-01-15 2014-01-15
US201461978719P 2014-04-11 2014-04-11
PCT/US2014/046436 WO2015006749A2 (en) 2013-07-12 2014-07-11 Bispecific cd3 and cd19 antigen binding contructs

Publications (1)

Publication Number Publication Date
MX2016000272A true MX2016000272A (es) 2016-08-03

Family

ID=52280737

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016000272A MX2016000272A (es) 2013-07-12 2014-07-11 Construcciones de unión a los antígenos cd19 y cd3 biespecificos.

Country Status (11)

Country Link
US (1) US20160355588A1 (es)
EP (1) EP3019622A4 (es)
JP (1) JP2016531100A (es)
KR (1) KR20160029128A (es)
CN (1) CN105531374A (es)
AU (1) AU2014287011A1 (es)
BR (1) BR112016000666A2 (es)
CA (1) CA2917886A1 (es)
MX (1) MX2016000272A (es)
RU (1) RU2016104130A (es)
WO (1) WO2015006749A2 (es)

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CN104822704B (zh) * 2012-06-14 2020-02-14 医疗生物科学有限公司 针对分化簇3(cd3)的人源化的抗体
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JOP20200236A1 (ar) 2012-09-21 2017-06-16 Regeneron Pharma الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
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TWI635098B (zh) 2013-02-01 2018-09-11 再生元醫藥公司 含嵌合恆定區之抗體
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US10465006B2 (en) * 2013-07-05 2019-11-05 Genmab A/S Humanized or chimeric CD3 antibodies
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BR112016027888A2 (pt) 2014-05-28 2017-10-24 Zymeworks Inc construto de polipeptídeo de ligação ao antígeno isolado, polinucleotídeo isolado ou um conjunto de polinucleotídeos isolados, vetor ou conjunto de vetores, célula isolada, composição farmacêutica, uso do construto, método para tratar um sujeito com uma doença ou distúrbio, método para obter um construto, método para preparar um construto, meio de armazenamento legível por computador, método para produzir um construto de polipeptídeo de ligação com antígeno bi-específico e método para preparar um construto de polipeptídeo de ligação com antígeno isolado
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PT3699198T (pt) 2014-11-17 2025-04-29 Regeneron Pharma Métodos para o tratamento de tumores usando anticorpos biespecíficos cd3xcd20
IL289946B2 (en) * 2015-01-08 2025-06-01 Genmab As Bispecific antibodies against CD3 and CD20
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WO2016205200A1 (en) 2015-06-16 2016-12-22 Genentech, Inc. Anti-cll-1 antibodies and methods of use
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