MX2015015341A - Cepas de salmonella para uso en el tratamiento y/o prevencion de cancer. - Google Patents
Cepas de salmonella para uso en el tratamiento y/o prevencion de cancer.Info
- Publication number
- MX2015015341A MX2015015341A MX2015015341A MX2015015341A MX2015015341A MX 2015015341 A MX2015015341 A MX 2015015341A MX 2015015341 A MX2015015341 A MX 2015015341A MX 2015015341 A MX2015015341 A MX 2015015341A MX 2015015341 A MX2015015341 A MX 2015015341A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- prevention
- treatment
- salmonella strains
- salmonella enterica
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title abstract 2
- 241000607142 Salmonella Species 0.000 title 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 abstract 2
- 230000002238 attenuated effect Effects 0.000 abstract 2
- 206010005003 Bladder cancer Diseases 0.000 abstract 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 201000005112 urinary bladder cancer Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La presente invención se relaciona con una composición farmacéutica que comprende un mutante no recombinante atenuado vivo de la cepa de Salmonella entérica serovariedad typhi y/o un mutante no recombinante atenuado no viable de la cepa Salmonella enterica serovariedad typhi para uso en el tratamiento y/o prevención de recurrencia/progreso de cáncer. Preferiblemente, el cáncer es cáncer de vejiga.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13166851.9A EP2801364A1 (en) | 2013-05-07 | 2013-05-07 | Salmonella strain for use in the treatment and/or prevention of cancer |
| PCT/EP2014/059392 WO2014180929A1 (en) | 2013-05-07 | 2014-05-07 | Salmonella strains for use in the treatment and/or prevention of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015015341A true MX2015015341A (es) | 2016-06-21 |
| MX380345B MX380345B (es) | 2025-03-12 |
Family
ID=48227075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015015341A MX380345B (es) | 2013-05-07 | 2014-05-07 | Cepas de salmonella para uso en el tratamiento y/o prevencion de cancer. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9795641B2 (es) |
| EP (2) | EP2801364A1 (es) |
| CN (1) | CN105377276A (es) |
| CA (1) | CA2910072C (es) |
| ES (1) | ES2903026T3 (es) |
| MX (1) | MX380345B (es) |
| WO (1) | WO2014180929A1 (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11951140B2 (en) | 2011-02-04 | 2024-04-09 | Seed Health, Inc. | Modulation of an individual's gut microbiome to address osteoporosis and bone disease |
| US12533312B2 (en) | 2011-02-04 | 2026-01-27 | Seed Health, Inc. | Method and system for preventing sore throat in humans |
| US11844720B2 (en) | 2011-02-04 | 2023-12-19 | Seed Health, Inc. | Method and system to reduce the likelihood of dental caries and halitosis |
| US11998479B2 (en) | 2011-02-04 | 2024-06-04 | Seed Health, Inc. | Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure |
| US12257272B2 (en) | 2015-12-24 | 2025-03-25 | Seed Health, Inc. | Method and system for reducing the likelihood of developing depression in an individual |
| US12279989B2 (en) | 2011-02-04 | 2025-04-22 | Seed Health, Inc. | Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity |
| US11951139B2 (en) | 2015-11-30 | 2024-04-09 | Seed Health, Inc. | Method and system for reducing the likelihood of osteoporosis |
| US11969445B2 (en) | 2013-12-20 | 2024-04-30 | Seed Health, Inc. | Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH |
| US11980643B2 (en) | 2013-12-20 | 2024-05-14 | Seed Health, Inc. | Method and system to modify an individual's gut-brain axis to provide neurocognitive protection |
| US11839632B2 (en) | 2013-12-20 | 2023-12-12 | Seed Health, Inc. | Topical application of CRISPR-modified bacteria to treat acne vulgaris |
| US11998574B2 (en) | 2013-12-20 | 2024-06-04 | Seed Health, Inc. | Method and system for modulating an individual's skin microbiome |
| US12005085B2 (en) | 2013-12-20 | 2024-06-11 | Seed Health, Inc. | Probiotic method and composition for maintaining a healthy vaginal microbiome |
| US11642382B2 (en) | 2013-12-20 | 2023-05-09 | Seed Health, Inc. | Method for treating an individual suffering from bladder cancer |
| US11672835B2 (en) | 2013-12-20 | 2023-06-13 | Seed Health, Inc. | Method for treating individuals having cancer and who are receiving cancer immunotherapy |
| US12246043B2 (en) | 2013-12-20 | 2025-03-11 | Seed Health, Inc. | Topical application to treat acne vulgaris |
| US11826388B2 (en) | 2013-12-20 | 2023-11-28 | Seed Health, Inc. | Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation |
| US11833177B2 (en) | 2013-12-20 | 2023-12-05 | Seed Health, Inc. | Probiotic to enhance an individual's skin microbiome |
| US12329783B2 (en) | 2013-12-20 | 2025-06-17 | Seed Health, Inc. | Method and system to improve the health of a person's skin microbiome |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| EP3922255A1 (en) | 2020-06-10 | 2021-12-15 | Prokarium Limited | Cancer therapy |
| US12537071B1 (en) | 2020-07-22 | 2026-01-27 | David Gordon Bermudes | Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins |
| US20240009252A1 (en) * | 2020-08-18 | 2024-01-11 | Curators Of The University Of Missouri | Compositions and methods of treatment comprising tumor-targeting bacteria and chemotherapy or immunotherapy agent |
| EP4124342A1 (en) * | 2021-07-28 | 2023-02-01 | Prokarium Limited | Cancer therapy with live attenuated bacteria |
| JP2025531378A (ja) | 2022-09-21 | 2025-09-19 | プロカリウム リミテッド | 染色体上にランディングパッドが統合されたサルモネラ株 |
| GB202215576D0 (en) | 2022-10-21 | 2022-12-07 | Prokarium Ltd | Circuit |
| GB202405780D0 (en) | 2024-04-24 | 2024-06-05 | Prokarium Ltd | Vacuole escape |
| WO2025224251A1 (en) | 2024-04-24 | 2025-10-30 | Prokarium Limited | Modified microorganisms |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6037332A (en) * | 1996-02-20 | 2000-03-14 | Emory University | Method of urinary bladder instillation |
| GB9621091D0 (en) * | 1996-10-09 | 1996-11-27 | Fondation Pour Le Perfectionem | Attenuated microorganisms strains and their uses |
| US6962696B1 (en) * | 1999-10-04 | 2005-11-08 | Vion Pharmaceuticals Inc. | Compositions and methods for tumor-targeted delivery of effector molecules |
| US20050180985A9 (en) | 2001-10-04 | 2005-08-18 | Vladoianu Ion R. | Live attenuated salmonella strains for producing monovalent or multivalent vaccines |
| WO2003063593A1 (en) * | 2002-01-28 | 2003-08-07 | Vion Pharmaceuticals, Inc. | Methods for treating cancer by administering tumor-targetted bacteria and an immunomodulatory agent |
| US20070298012A1 (en) * | 2003-12-16 | 2007-12-27 | Ivan King | Compositions and Methods for Tumor-Targeted Delivery of Effector Molecules |
| CN101115766B (zh) * | 2004-06-18 | 2013-05-08 | 印度免疫有限公司 | 用于抗人乳头瘤病毒型16的salmonella疫苗菌株的密码子经优化的hpv16l1 |
| JP2008527001A (ja) * | 2005-01-13 | 2008-07-24 | ザ ジョンズ ホプキンス ユニバーシティー | 前立腺幹細胞抗原ワクチンおよびその使用 |
| EP1928492B1 (en) * | 2005-09-01 | 2011-02-23 | Celgene Corporation | Immunological uses of immunodulatory compounds for vaccine and anti-infections disease therapy |
| CN1974759B (zh) * | 2006-07-26 | 2010-06-09 | 吉林大学 | 运载重组质粒的减毒沙门氏菌及其在抗肿瘤中的应用 |
| CN101204584A (zh) * | 2007-12-17 | 2008-06-25 | 北京娜可长今国际银离子科技开发有限公司 | 以减毒沙门氏菌为载体的肿瘤疫苗及其制备方法 |
| EP2085466A1 (en) * | 2008-01-29 | 2009-08-05 | AEterna Zentaris GmbH | Non-pathogenic and/or attenuated bacteria capable of inducing apoptosis in macrophages, process of manufacturing and uses thereof |
| WO2009098246A1 (en) * | 2008-02-05 | 2009-08-13 | Æterna Zentaris Gmbh | Recombinant bacteria with e. coli hemolysin secretion system and increased expression and/or secretion of hlya, process of manufacturing and uses thereof |
-
2013
- 2013-05-07 EP EP13166851.9A patent/EP2801364A1/en not_active Withdrawn
-
2014
- 2014-05-07 CA CA2910072A patent/CA2910072C/en active Active
- 2014-05-07 EP EP14725051.8A patent/EP2996699B1/en active Active
- 2014-05-07 ES ES14725051T patent/ES2903026T3/es active Active
- 2014-05-07 MX MX2015015341A patent/MX380345B/es unknown
- 2014-05-07 WO PCT/EP2014/059392 patent/WO2014180929A1/en not_active Ceased
- 2014-05-07 US US14/888,831 patent/US9795641B2/en active Active
- 2014-05-07 CN CN201480038964.3A patent/CN105377276A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2910072A1 (en) | 2014-11-13 |
| US20160074441A1 (en) | 2016-03-17 |
| EP2996699B1 (en) | 2021-10-20 |
| US9795641B2 (en) | 2017-10-24 |
| ES2903026T3 (es) | 2022-03-30 |
| EP2801364A1 (en) | 2014-11-12 |
| WO2014180929A1 (en) | 2014-11-13 |
| CA2910072C (en) | 2024-01-23 |
| EP2996699A1 (en) | 2016-03-23 |
| MX380345B (es) | 2025-03-12 |
| CN105377276A (zh) | 2016-03-02 |
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