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MX2015014939A - Nuevo uso de clorhidrato de landiolol en el tratamiento a largo plazo de taquiarritmias e hipertension. - Google Patents

Nuevo uso de clorhidrato de landiolol en el tratamiento a largo plazo de taquiarritmias e hipertension.

Info

Publication number
MX2015014939A
MX2015014939A MX2015014939A MX2015014939A MX2015014939A MX 2015014939 A MX2015014939 A MX 2015014939A MX 2015014939 A MX2015014939 A MX 2015014939A MX 2015014939 A MX2015014939 A MX 2015014939A MX 2015014939 A MX2015014939 A MX 2015014939A
Authority
MX
Mexico
Prior art keywords
landiolol
hydrochloride
period
blood pressure
heart rate
Prior art date
Application number
MX2015014939A
Other languages
English (en)
Other versions
MX379191B (es
Inventor
Günther Krumpl
Original Assignee
Aop Orphan Pharmaceuticals Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48226997&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2015014939(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aop Orphan Pharmaceuticals Ag filed Critical Aop Orphan Pharmaceuticals Ag
Publication of MX2015014939A publication Critical patent/MX2015014939A/es
Publication of MX379191B publication Critical patent/MX379191B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

La invención proporciona un nuevo uso de clorhidrato de landiolol para la reducción persistente de la frecuencia cardíaca durante el período de administración de clorhidrato de landiolol en el tratamiento de un ser humano que sufre de taquicardia, taquiarritmia o presión sanguínea elevada, en donde el clorhidrato de landiolol se administra en una dosis constante de más de 5 µg/kg/min, específicamente de al menos 10 µg/kg/min durante un período de al menos 2 horas y en donde la frecuencia cardíaca y/o presión sanguínea de dicho paciente se reducen de modo persistente durante el período de administración en comparación con la frecuencia cardíaca y/o presión sanguínea antes del tratamiento y no se produce ningún efecto de "overshoot" después de la terminación de dicha administración.
MX2015014939A 2013-04-26 2014-04-25 Nuevo uso de clorhidrato de landiolol en el tratamiento a largo plazo de taquiarritmias e hipertension. MX379191B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13165582.1A EP2796139A1 (en) 2013-04-26 2013-04-26 Use of landiolol hydrochloride in the long-term treatment of tachyarrhythmias
PCT/EP2014/058456 WO2014174076A1 (en) 2013-04-26 2014-04-25 Use of landiolol hydrochloride in the long-term treatment of tachyarrhythmias

Publications (2)

Publication Number Publication Date
MX2015014939A true MX2015014939A (es) 2016-01-12
MX379191B MX379191B (es) 2025-03-10

Family

ID=48226997

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015014939A MX379191B (es) 2013-04-26 2014-04-25 Nuevo uso de clorhidrato de landiolol en el tratamiento a largo plazo de taquiarritmias e hipertension.

Country Status (28)

Country Link
US (1) US10722516B2 (es)
EP (2) EP2796139A1 (es)
JP (1) JP2016517860A (es)
KR (1) KR102268161B1 (es)
CN (1) CN105324118A (es)
AU (1) AU2014259352B2 (es)
BR (1) BR112015027051A2 (es)
CA (1) CA2910066C (es)
CL (1) CL2015003145A1 (es)
DK (1) DK2988750T4 (es)
EA (1) EA030589B1 (es)
ES (1) ES2906551T3 (es)
FI (1) FI2988750T4 (es)
HR (1) HRP20220470T4 (es)
HU (1) HUE058189T2 (es)
IL (1) IL242220B (es)
LT (1) LT2988750T (es)
MX (1) MX379191B (es)
NZ (1) NZ713295A (es)
PH (1) PH12015502465A1 (es)
PL (1) PL2988750T5 (es)
PT (1) PT2988750T (es)
SG (1) SG11201508824RA (es)
SI (1) SI2988750T2 (es)
TN (1) TN2015000480A1 (es)
UA (1) UA117243C2 (es)
WO (1) WO2014174076A1 (es)
ZA (1) ZA201508050B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2796139A1 (en) 2013-04-26 2014-10-29 AOP Orphan Pharmaceuticals AG Use of landiolol hydrochloride in the long-term treatment of tachyarrhythmias
EP4146198A4 (en) 2020-05-08 2024-05-15 Psilera Inc. Novel compositions of matter and pharmaceutical compositions
AU2022281358A1 (en) 2021-05-25 2023-11-23 Atai Therapeutics, Inc. New n,n-dimethyltryptamine salts and crystalline salt forms
CN114031601B (zh) * 2022-01-12 2022-03-18 南京桦冠生物技术有限公司 一种盐酸兰地洛尔的制备方法
WO2025024637A1 (en) * 2023-07-25 2025-01-30 Atai Therapeutics, Inc. Compositions for limiting sympathomimetic effects of psychedelic therapeutics
CN118975994B (zh) * 2024-08-26 2025-10-28 北京阳光诺和药物研究股份有限公司 一种注射用β-阻滞剂的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004323370A (ja) 2003-04-22 2004-11-18 Ono Pharmaceut Co Ltd 麻酔薬と塩酸ランジオロールとを組み合わせてなる併用剤
JP4816083B2 (ja) 2003-08-08 2011-11-16 小野薬品工業株式会社 短時間型β遮断薬を有効成分とする心拍数減少剤
JP4784037B2 (ja) 2003-08-27 2011-09-28 独立行政法人国立がん研究センター 塩酸ランジオロールを含有する頻脈性不整脈の治療剤
CN1827109A (zh) 2006-04-14 2006-09-06 北京润德康医药技术有限公司 一种以兰洛地尔及其盐为活性成分的冻干粉针制剂及其制备工艺
ES2397126T3 (es) * 2007-12-21 2013-03-04 Aop Orphan Pharmaceuticals Ag Composición farmacéutica para la administración parenteral de un antagonista del receptor beta-adrenérgico de acción ultrarrápida
CN101732319B (zh) 2008-11-26 2012-11-07 天津市汉康医药生物技术有限公司 含有盐酸兰地洛尔活性成分的注射用药物组合物及其制备方法
CN102232930B (zh) 2010-05-06 2013-03-27 南京海辰药业有限公司 盐酸兰地洛尔药物组合物及其制备方法
JP2010248263A (ja) 2010-08-04 2010-11-04 National Cancer Center 塩酸ランジオロールを含有する頻脈性不整脈の治療剤
CN102475706A (zh) 2010-11-28 2012-05-30 天津市汉康医药生物技术有限公司 一种供注射用盐酸兰地洛尔药物组合物及其制备方法
EP2796139A1 (en) 2013-04-26 2014-10-29 AOP Orphan Pharmaceuticals AG Use of landiolol hydrochloride in the long-term treatment of tachyarrhythmias

Also Published As

Publication number Publication date
EP2988750B2 (en) 2025-05-28
KR102268161B1 (ko) 2021-06-23
US10722516B2 (en) 2020-07-28
LT2988750T (lt) 2022-05-10
KR20160020411A (ko) 2016-02-23
EP2988750A1 (en) 2016-03-02
CN105324118A (zh) 2016-02-10
EP2796139A1 (en) 2014-10-29
DK2988750T4 (da) 2025-08-18
ZA201508050B (en) 2017-11-29
EP2988750B1 (en) 2022-01-19
CA2910066C (en) 2021-10-19
HK1214511A1 (zh) 2016-07-29
WO2014174076A1 (en) 2014-10-30
FI2988750T4 (fi) 2025-08-07
AU2014259352B2 (en) 2017-03-02
US20160074411A1 (en) 2016-03-17
IL242220B (en) 2020-07-30
DK2988750T3 (da) 2022-04-04
NZ713295A (en) 2020-08-28
PL2988750T5 (pl) 2025-09-22
SG11201508824RA (en) 2015-11-27
IL242220A0 (en) 2015-11-30
PT2988750T (pt) 2022-03-01
UA117243C2 (uk) 2018-07-10
EA201592058A1 (ru) 2016-03-31
JP2016517860A (ja) 2016-06-20
MX379191B (es) 2025-03-10
SI2988750T1 (sl) 2022-05-31
TN2015000480A1 (en) 2017-04-06
CL2015003145A1 (es) 2016-06-24
HUE058189T2 (hu) 2022-07-28
ES2906551T3 (es) 2022-04-19
PH12015502465A1 (en) 2016-02-22
EA030589B1 (ru) 2018-08-31
PL2988750T3 (pl) 2022-05-16
EP2988750B9 (en) 2025-09-17
AU2014259352A1 (en) 2015-11-05
HRP20220470T4 (hr) 2025-11-07
BR112015027051A2 (pt) 2020-03-10
HRP20220470T1 (hr) 2022-05-27
SI2988750T2 (sl) 2025-08-29
CA2910066A1 (en) 2014-10-30

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