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MX2015012034A - El péptido mots3 derivado de mitocondrias regula el metabolismo y supervivencia celular. - Google Patents

El péptido mots3 derivado de mitocondrias regula el metabolismo y supervivencia celular.

Info

Publication number
MX2015012034A
MX2015012034A MX2015012034A MX2015012034A MX2015012034A MX 2015012034 A MX2015012034 A MX 2015012034A MX 2015012034 A MX2015012034 A MX 2015012034A MX 2015012034 A MX2015012034 A MX 2015012034A MX 2015012034 A MX2015012034 A MX 2015012034A
Authority
MX
Mexico
Prior art keywords
mots3
mitochondrial
cell survival
derived peptide
regulates metabolism
Prior art date
Application number
MX2015012034A
Other languages
English (en)
Other versions
MX371272B (es
Inventor
Pinchas Cohen
Changhan Lee
Laura J Cobb
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of MX2015012034A publication Critical patent/MX2015012034A/es
Publication of MX371272B publication Critical patent/MX371272B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

MOTS3 es un nuevo péptido. En el presente documento se presentan los métodos y las composiciones farmacéuticas del mismo que utilizan MOTS3 para el tratamiento de enfermedades como la diabetes, la obesidad, el hígado graso y el cáncer.
MX2015012034A 2013-03-15 2014-03-14 El péptido mots3 derivado de mitocondrias regula el metabolismo y la supervivencia celular. MX371272B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361801474P 2013-03-15 2013-03-15
PCT/US2014/028968 WO2014144521A1 (en) 2013-03-15 2014-03-14 Mitochondrial-derived peptide mots3 regulates metabolism and cell survival

Publications (2)

Publication Number Publication Date
MX2015012034A true MX2015012034A (es) 2016-03-17
MX371272B MX371272B (es) 2020-01-22

Family

ID=51537724

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015012034A MX371272B (es) 2013-03-15 2014-03-14 El péptido mots3 derivado de mitocondrias regula el metabolismo y la supervivencia celular.

Country Status (11)

Country Link
US (3) US20140296139A1 (es)
EP (1) EP2970410B1 (es)
JP (1) JP6640076B2 (es)
KR (1) KR102267292B1 (es)
CN (1) CN105229023B (es)
AU (1) AU2014228999B2 (es)
BR (1) BR112015023500B1 (es)
CA (1) CA2906037C (es)
MX (1) MX371272B (es)
TW (1) TWI691507B (es)
WO (1) WO2014144521A1 (es)

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CN110818804B (zh) * 2019-10-21 2021-06-04 兰州大学 脑靶向肽及其在制备增强记忆药物中的应用
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Also Published As

Publication number Publication date
CA2906037C (en) 2021-08-03
WO2014144521A1 (en) 2014-09-18
CA2906037A1 (en) 2014-09-18
US20180360910A1 (en) 2018-12-20
EP2970410A4 (en) 2016-10-19
US10064914B2 (en) 2018-09-04
US20140296139A1 (en) 2014-10-02
AU2014228999B2 (en) 2018-07-26
EP2970410B1 (en) 2020-01-22
CN105229023A (zh) 2016-01-06
US20170049853A1 (en) 2017-02-23
KR20150131176A (ko) 2015-11-24
TWI691507B (zh) 2020-04-21
JP2016514681A (ja) 2016-05-23
TW201534617A (zh) 2015-09-16
US10391143B2 (en) 2019-08-27
CN105229023B (zh) 2019-08-16
AU2014228999A1 (en) 2015-10-15
EP2970410A1 (en) 2016-01-20
BR112015023500B1 (pt) 2021-01-12
MX371272B (es) 2020-01-22
KR102267292B1 (ko) 2021-06-21
BR112015023500A2 (pt) 2017-10-10
JP6640076B2 (ja) 2020-02-05

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