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MX2015011429A - Sales de amina de pitavastatina y rosuvastatina. - Google Patents

Sales de amina de pitavastatina y rosuvastatina.

Info

Publication number
MX2015011429A
MX2015011429A MX2015011429A MX2015011429A MX2015011429A MX 2015011429 A MX2015011429 A MX 2015011429A MX 2015011429 A MX2015011429 A MX 2015011429A MX 2015011429 A MX2015011429 A MX 2015011429A MX 2015011429 A MX2015011429 A MX 2015011429A
Authority
MX
Mexico
Prior art keywords
amine salts
pitavastatin
rosuvastatin
hmg
coa reductase
Prior art date
Application number
MX2015011429A
Other languages
English (en)
Other versions
MX361000B (es
Inventor
Ben De Lange
Henricus Leonardus Marie Elsenberg
Karin Henderika Maria Bessembinder
Original Assignee
Dsm Sinochem Pharm Nl Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Sinochem Pharm Nl Bv filed Critical Dsm Sinochem Pharm Nl Bv
Publication of MX2015011429A publication Critical patent/MX2015011429A/es
Publication of MX361000B publication Critical patent/MX361000B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C07C209/78—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton from carbonyl compounds, e.g. from formaldehyde, and amines having amino groups bound to carbon atoms of six-membered aromatic rings, with formation of methylene-diarylamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/62—Quaternary ammonium compounds
    • C07C211/63—Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)

Abstract

La presente invención se relaciona con sales de amina insaturadas de inhibidores de HMG-CoA reductasa, con un método para producir dichas sales de amina y con el uso de dichas sales de amina en la producción de sales farmacéuticamente aceptables de inhibidores de HGM-CoA reductasa.
MX2015011429A 2013-03-29 2014-03-28 Sales de amina de pitavastatina y rosuvastatina. MX361000B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13161843 2013-03-29
EP13182231 2013-08-29
PCT/EP2014/056267 WO2014154856A1 (en) 2013-03-29 2014-03-28 Amine salts of pravastatin and rosuvastatin

Publications (2)

Publication Number Publication Date
MX2015011429A true MX2015011429A (es) 2016-02-03
MX361000B MX361000B (es) 2018-11-23

Family

ID=50391178

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015011429A MX361000B (es) 2013-03-29 2014-03-28 Sales de amina de pitavastatina y rosuvastatina.

Country Status (7)

Country Link
US (1) US9630906B2 (es)
EP (1) EP2978743B1 (es)
CN (1) CN105189458A (es)
HK (1) HK1220687A1 (es)
IL (1) IL241435A0 (es)
MX (1) MX361000B (es)
WO (1) WO2014154856A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2015013696A (es) 2013-03-29 2016-02-26 Dsm Sinochem Pharm Nl Bv Sales de amina de pitavastatina y rosuvastatina.
FR3083119A1 (fr) * 2018-06-27 2020-01-03 L'oreal Procede de coloration des fibres keratiniques a partir de poudre et/ou extrait de plantes indigoferes et de composes de type furfurylamine

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3528186B2 (ja) * 1991-06-24 2004-05-17 日産化学工業株式会社 光学活性キノリンメバロン酸のジアステレオマー塩
CA2612587C (en) * 2005-06-24 2013-02-19 Lek Pharmaceuticals D.D. Process for preparing amorphous rosuvastatin calcium free of impurities
WO2008038132A1 (en) * 2006-09-28 2008-04-03 Aurobindo Pharma Limited Crystalline diamine salts of rosuvastatin
JP5533654B2 (ja) * 2008-09-05 2014-06-25 日産化学工業株式会社 ３，５−ジヒドロキシ−６−ヘプテン酸アミン塩類の製造方法
WO2010035284A2 (en) * 2008-09-26 2010-04-01 Matrix Laboratories Ltd An improved process for the preparation of rosuvastatin calcium
EP2383260A3 (en) * 2010-04-30 2011-12-28 Dipharma Francis S.r.l. Process for the preparation of statins
MX2010011006A (es) * 2010-10-06 2012-04-18 Senosiain S A De C V Lab Nueva sal de un derivado de pirimidina.
WO2012063115A2 (en) 2010-11-11 2012-05-18 Jubilant Life Sciences Ltd. Process for the preparation of rosuvastatin calcium via novel amine intermediate
WO2012106584A2 (en) * 2011-02-04 2012-08-09 Dr. Reddy's Laboratories Ltd. Pitavastatin salts
WO2012176218A1 (en) * 2011-06-24 2012-12-27 Ind-Swift Laboratories Limited Process for preparing rosuvastatin calcium through novel amine salt
EP2751081B1 (en) * 2011-09-12 2017-01-04 Farma GRS, d.o.o. Polymorphic form of pitavastatin calcium

Also Published As

Publication number Publication date
US9630906B2 (en) 2017-04-25
HK1220687A1 (zh) 2017-05-12
EP2978743A1 (en) 2016-02-03
WO2014154856A1 (en) 2014-10-02
US20160052864A1 (en) 2016-02-25
MX361000B (es) 2018-11-23
IL241435A0 (en) 2015-11-30
WO2014154856A8 (en) 2014-11-27
CN105189458A (zh) 2015-12-23
EP2978743B1 (en) 2019-11-27

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