MX2015003074A - Formulaciones que comprenden idebenona, n-acetil-s-farnesil-l-cist eína y ergotioneína y usos de las mismas. - Google Patents
Formulaciones que comprenden idebenona, n-acetil-s-farnesil-l-cist eína y ergotioneína y usos de las mismas.Info
- Publication number
- MX2015003074A MX2015003074A MX2015003074A MX2015003074A MX2015003074A MX 2015003074 A MX2015003074 A MX 2015003074A MX 2015003074 A MX2015003074 A MX 2015003074A MX 2015003074 A MX2015003074 A MX 2015003074A MX 2015003074 A MX2015003074 A MX 2015003074A
- Authority
- MX
- Mexico
- Prior art keywords
- ergothioneine
- idebenone
- farnesyl
- cysteine
- acetyl
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- XTURYZYJYQRJDO-BNAHBJSTSA-N Acetyl-farnesyl-cysteine Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CSC[C@@H](C(O)=O)NC(C)=O XTURYZYJYQRJDO-BNAHBJSTSA-N 0.000 title abstract 2
- SSISHJJTAXXQAX-ZETCQYMHSA-N L-ergothioneine Chemical compound C[N+](C)(C)[C@H](C([O-])=O)CC1=CNC(=S)N1 SSISHJJTAXXQAX-ZETCQYMHSA-N 0.000 title abstract 2
- 229940093497 ergothioneine Drugs 0.000 title abstract 2
- JGPMMRGNQUBGND-UHFFFAOYSA-N idebenone Chemical compound COC1=C(OC)C(=O)C(CCCCCCCCCCO)=C(C)C1=O JGPMMRGNQUBGND-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004135 idebenone Drugs 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- 150000002148 esters Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 230000007613 environmental effect Effects 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
- A61K8/355—Quinones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/596—Mixtures of surface active compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
La presente invención se refiere a composiciones que mitigan el daño causado por factores de estrés ambientales. Los factores de estrés incluyen, pero no se limitan a, daño causado por radiación ultra-violeta. Las composiciones comprenden una cantidad efectiva de idebenona o un derivado de la misma, N-acetil-S-farnesil-L-cist eína o una sal o éster de la misma farmacéuticamente aceptable y ergotioneína o una sal o éster de la misma farmacéuticamente aceptable. En algunas modalidades estas composiciones son aplicadas tópicamente a la piel de una persona.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261701098P | 2012-09-14 | 2012-09-14 | |
| US201361815771P | 2013-04-25 | 2013-04-25 | |
| PCT/US2013/059257 WO2014043230A2 (en) | 2012-09-14 | 2013-09-11 | Formulations comprising idebenone, n-acetyl-s-farnesyl-l-cysteine and ergothioneine and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015003074A true MX2015003074A (es) | 2015-11-09 |
Family
ID=50278844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015003074A MX2015003074A (es) | 2012-09-14 | 2013-09-11 | Formulaciones que comprenden idebenona, n-acetil-s-farnesil-l-cist eína y ergotioneína y usos de las mismas. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20160243011A1 (es) |
| EP (1) | EP2895159A4 (es) |
| JP (1) | JP2015528499A (es) |
| KR (1) | KR20150055024A (es) |
| CN (1) | CN104853753A (es) |
| AU (1) | AU2013315557A1 (es) |
| BR (1) | BR112015005789A2 (es) |
| CA (1) | CA2884115A1 (es) |
| HK (1) | HK1206621A1 (es) |
| IL (1) | IL237693A0 (es) |
| MX (1) | MX2015003074A (es) |
| RU (1) | RU2015112839A (es) |
| SG (1) | SG11201501892SA (es) |
| WO (1) | WO2014043230A2 (es) |
| ZA (1) | ZA201501857B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014036528A2 (en) | 2012-08-31 | 2014-03-06 | Ixchel Pharma, Llc | Agents useful for treating obesity, diabetes and related disorders |
| PT107561A (pt) * | 2014-04-01 | 2015-10-01 | Amorim Cork Res Lda | Extracto hidro-glicólico de cortiça, processo para a sua preparação, formulações compreendendo o referido extracto e sua utilização |
| AU2016233559A1 (en) | 2015-03-13 | 2017-11-02 | Mironova Innovations, Llc | Nalpha, Nalpha, Nalpha-trialkyl histidine derivatives useful for the preparation of ergothioneine compounds |
| US10363207B2 (en) * | 2016-04-29 | 2019-07-30 | Purvisha Patel | All-in-one skin-brightening formulations |
| CN109276578A (zh) * | 2018-11-07 | 2019-01-29 | 上海上水和肌化妆品有限公司 | 由能量转换促进皮肤抗醣化作用的组合物及其制备方法 |
| JP7727671B2 (ja) * | 2021-02-03 | 2025-08-21 | 長瀬産業株式会社 | ホモシステイン誘導体及びその製造方法、組成物、並びに、炎症抑制剤 |
| CN115350167A (zh) * | 2022-09-29 | 2022-11-18 | 陕西中鸿科瑞再生医学研究院有限公司 | 艾地苯醌在制备降尿酸药物中的应用 |
| CN115645296B (zh) * | 2022-11-15 | 2024-04-26 | 杭州唯铂莱生物科技有限公司 | 一种化妆品组合物、制备方法及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8338648B2 (en) * | 2004-06-12 | 2012-12-25 | Signum Biosciences, Inc. | Topical compositions and methods for epithelial-related conditions |
| WO2005123103A1 (en) * | 2004-06-12 | 2005-12-29 | Signum Biosciences, Inc. | Topical compositions and methods for epithelial-related conditions |
| US20060263320A1 (en) * | 2005-05-17 | 2006-11-23 | The Procter & Gamble Company | Regulation of mammalian keratinous tissue using personal care compositions comprising ergothioneine |
| CN101175467A (zh) * | 2005-05-17 | 2008-05-07 | 宝洁公司 | 使用包含四氢姜黄素的个人护理组合物调节哺乳动物的角质组织 |
| WO2010051138A2 (en) * | 2008-10-06 | 2010-05-06 | Pharma Cosmetix Research, Llc | Skin treatments containing carboxylic acid-substituted idebenone derivatives and methods of preparation and use thereof |
-
2013
- 2013-09-11 AU AU2013315557A patent/AU2013315557A1/en not_active Abandoned
- 2013-09-11 EP EP13836558.0A patent/EP2895159A4/en not_active Withdrawn
- 2013-09-11 BR BR112015005789A patent/BR112015005789A2/pt not_active IP Right Cessation
- 2013-09-11 JP JP2015532021A patent/JP2015528499A/ja active Pending
- 2013-09-11 HK HK15107270.9A patent/HK1206621A1/xx unknown
- 2013-09-11 CN CN201380055596.9A patent/CN104853753A/zh active Pending
- 2013-09-11 CA CA2884115A patent/CA2884115A1/en not_active Abandoned
- 2013-09-11 US US14/426,777 patent/US20160243011A1/en not_active Abandoned
- 2013-09-11 KR KR1020157009426A patent/KR20150055024A/ko not_active Withdrawn
- 2013-09-11 SG SG11201501892SA patent/SG11201501892SA/en unknown
- 2013-09-11 RU RU2015112839A patent/RU2015112839A/ru not_active Application Discontinuation
- 2013-09-11 WO PCT/US2013/059257 patent/WO2014043230A2/en not_active Ceased
- 2013-09-11 MX MX2015003074A patent/MX2015003074A/es unknown
-
2015
- 2015-03-12 IL IL237693A patent/IL237693A0/en unknown
- 2015-03-18 ZA ZA2015/01857A patent/ZA201501857B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2013315557A1 (en) | 2015-03-26 |
| US20160243011A1 (en) | 2016-08-25 |
| KR20150055024A (ko) | 2015-05-20 |
| RU2015112839A (ru) | 2016-11-10 |
| WO2014043230A3 (en) | 2014-07-10 |
| EP2895159A4 (en) | 2016-06-08 |
| WO2014043230A2 (en) | 2014-03-20 |
| HK1206621A1 (en) | 2016-01-15 |
| EP2895159A2 (en) | 2015-07-22 |
| JP2015528499A (ja) | 2015-09-28 |
| ZA201501857B (en) | 2016-10-26 |
| CN104853753A (zh) | 2015-08-19 |
| IL237693A0 (en) | 2015-05-31 |
| CA2884115A1 (en) | 2014-03-20 |
| SG11201501892SA (en) | 2015-04-29 |
| BR112015005789A2 (pt) | 2018-06-26 |
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