MX2015001648A - Composiciones que comprenden derivados de espicamicina y metodos de uso de los mismos. - Google Patents
Composiciones que comprenden derivados de espicamicina y metodos de uso de los mismos.Info
- Publication number
- MX2015001648A MX2015001648A MX2015001648A MX2015001648A MX2015001648A MX 2015001648 A MX2015001648 A MX 2015001648A MX 2015001648 A MX2015001648 A MX 2015001648A MX 2015001648 A MX2015001648 A MX 2015001648A MX 2015001648 A MX2015001648 A MX 2015001648A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- methods
- spicamycin derivatives
- spicamycin
- derivatives
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- YBZRLMLGUBIIDN-NZSGCTDASA-N spicamycin Chemical class O1[C@@H](C(O)CO)[C@H](NC(=O)CNC(=O)CCCCCCCCCCCCC(C)C)[C@@H](O)[C@@H](O)[C@H]1NC1=NC=NC2=C1N=CN2 YBZRLMLGUBIIDN-NZSGCTDASA-N 0.000 title abstract 2
- 208000002193 Pain Diseases 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a composiciones que comprenden derivados de espicamicina, métodos para elaborar tales composiciones, y su uso en el tratamiento y/o prevención de dolor, que incluye dolor neuropático.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261681385P | 2012-08-09 | 2012-08-09 | |
| US201261730311P | 2012-11-27 | 2012-11-27 | |
| US201261736138P | 2012-12-12 | 2012-12-12 | |
| PCT/US2013/054100 WO2014025979A1 (en) | 2012-08-09 | 2013-08-08 | Compositions comprising spicamycin derivatives and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015001648A true MX2015001648A (es) | 2015-10-14 |
Family
ID=48998737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015001648A MX2015001648A (es) | 2012-08-09 | 2013-08-08 | Composiciones que comprenden derivados de espicamicina y metodos de uso de los mismos. |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US9078910B2 (es) |
| EP (1) | EP2882418A1 (es) |
| JP (1) | JP2015524482A (es) |
| KR (1) | KR20150038572A (es) |
| CN (1) | CN104822369A (es) |
| AU (1) | AU2013299560A1 (es) |
| CA (1) | CA2880853A1 (es) |
| MX (1) | MX2015001648A (es) |
| NZ (1) | NZ704342A (es) |
| WO (1) | WO2014025979A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015061481A1 (en) * | 2013-10-23 | 2015-04-30 | Dara Biosciences, Inc. | Methods of treating liquid tumors using compositions comprising spicamycin derivatives |
| WO2015153961A1 (en) * | 2014-04-03 | 2015-10-08 | Yan-Yeung Luk | Synthetic disugar hydrocarbons as natural analogos to control microbial behaviors |
| KR101779135B1 (ko) | 2016-04-05 | 2017-09-18 | 경북대학교 산학협력단 | 덱사메타손과 이부프로펜을 유효성분으로 포함하는 신경병증성 통증 예방 및 치료용 약학적 조성물 |
| CN110628937A (zh) * | 2019-10-28 | 2019-12-31 | 华中农业大学 | 玉米基因krn5在提高玉米产量中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2783722B2 (ja) | 1991-07-12 | 1998-08-06 | 麒麟麦酒株式会社 | スピカマイシン誘導体およびそれを含む抗腫瘍剤 |
| JP3066291B2 (ja) * | 1994-07-07 | 2000-07-17 | 麒麟麦酒株式会社 | 抗腫瘍薬物の用時調合型セット製剤 |
| US5905069A (en) * | 1998-01-26 | 1999-05-18 | The General Hospital Corporation | Methods of decreasing or preventing pain using spicamycin or derivatives thereof |
| EP1328236B1 (en) | 2000-09-20 | 2011-04-06 | The General Hospital Corporation | Methods of decreasing or preventing pain using spicamycin derivatives |
| US9248098B2 (en) * | 2008-10-10 | 2016-02-02 | Dara Biosciences, Inc. | Treating or preventing pain using spicamycin derivatives |
-
2013
- 2013-08-08 CN CN201380052794.XA patent/CN104822369A/zh active Pending
- 2013-08-08 EP EP13750461.9A patent/EP2882418A1/en not_active Withdrawn
- 2013-08-08 JP JP2015526699A patent/JP2015524482A/ja active Pending
- 2013-08-08 US US13/962,279 patent/US9078910B2/en not_active Expired - Fee Related
- 2013-08-08 MX MX2015001648A patent/MX2015001648A/es unknown
- 2013-08-08 WO PCT/US2013/054100 patent/WO2014025979A1/en not_active Ceased
- 2013-08-08 NZ NZ704342A patent/NZ704342A/en not_active IP Right Cessation
- 2013-08-08 AU AU2013299560A patent/AU2013299560A1/en not_active Abandoned
- 2013-08-08 KR KR1020157005543A patent/KR20150038572A/ko not_active Ceased
- 2013-08-08 CA CA2880853A patent/CA2880853A1/en not_active Abandoned
-
2015
- 2015-07-01 US US14/788,971 patent/US20150297721A1/en not_active Abandoned
-
2016
- 2016-06-08 US US15/176,691 patent/US20160279160A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20140045780A1 (en) | 2014-02-13 |
| US9078910B2 (en) | 2015-07-14 |
| CA2880853A1 (en) | 2014-02-13 |
| JP2015524482A (ja) | 2015-08-24 |
| KR20150038572A (ko) | 2015-04-08 |
| AU2013299560A1 (en) | 2015-02-26 |
| US20150297721A1 (en) | 2015-10-22 |
| NZ704342A (en) | 2016-04-29 |
| WO2014025979A1 (en) | 2014-02-13 |
| US20160279160A1 (en) | 2016-09-29 |
| CN104822369A (zh) | 2015-08-05 |
| EP2882418A1 (en) | 2015-06-17 |
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