MX2014015842A - Purificacion de particulas tipo virus. - Google Patents
Purificacion de particulas tipo virus.Info
- Publication number
- MX2014015842A MX2014015842A MX2014015842A MX2014015842A MX2014015842A MX 2014015842 A MX2014015842 A MX 2014015842A MX 2014015842 A MX2014015842 A MX 2014015842A MX 2014015842 A MX2014015842 A MX 2014015842A MX 2014015842 A MX2014015842 A MX 2014015842A
- Authority
- MX
- Mexico
- Prior art keywords
- particles
- virus
- purification
- methods
- vlps
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 239000000356 contaminant Substances 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 238000003306 harvesting Methods 0.000 abstract 1
- 230000002779 inactivation Effects 0.000 abstract 1
- 239000012678 infectious agent Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16051—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Analytical Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Métodos de purificación de partículas tipo virus (VLP), sustancialmente libres de contaminantes de proceso y agentes infecciosos. Los métodos incorporan, por ejemplo, un tratamiento a pH bajo durante la cosecha y/o inactivación con solvente y/o detergente durante la captura de las VLP.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261663218P | 2012-06-22 | 2012-06-22 | |
| US201361794086P | 2013-03-15 | 2013-03-15 | |
| PCT/US2013/047249 WO2013192604A1 (en) | 2012-06-22 | 2013-06-24 | Purification of virus like particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014015842A true MX2014015842A (es) | 2015-09-07 |
| MX366234B MX366234B (es) | 2019-07-03 |
Family
ID=49769461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014015842A MX366234B (es) | 2012-06-22 | 2013-06-24 | Purificacion de particulas tipo virus. |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US10167320B2 (es) |
| EP (1) | EP2864478B1 (es) |
| JP (1) | JP6553509B2 (es) |
| KR (1) | KR102110876B1 (es) |
| CN (2) | CN104583393A (es) |
| AR (1) | AR091538A1 (es) |
| AU (1) | AU2013277959B2 (es) |
| CA (1) | CA2879815A1 (es) |
| IN (1) | IN2015DN00089A (es) |
| JO (1) | JOP20130186B1 (es) |
| MX (1) | MX366234B (es) |
| SG (2) | SG10201610753YA (es) |
| TW (1) | TWI647310B (es) |
| UY (1) | UY34875A (es) |
| WO (1) | WO2013192604A1 (es) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2601970T3 (pl) | 2006-09-29 | 2017-07-31 | Takeda Vaccines, Inc. | Preparaty szczepionki przeciw norowirusowi |
| AU2008224877B2 (en) | 2007-03-14 | 2013-07-11 | Ligocyte Pharmaceuticals, Inc. | Virus like particle purification |
| SG10201601660YA (en) | 2007-09-18 | 2016-04-28 | Takeda Vaccines Inc | Method of conferring a protective immune response to norovirus |
| MX356586B (es) | 2011-07-11 | 2018-06-05 | Takeda Vaccines Inc | Formulaciones parenterales de vacunas contra los norovirus. |
| JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
| CN105339495A (zh) * | 2013-07-11 | 2016-02-17 | 宝生物工程株式会社 | 制备无包膜病毒的方法 |
| CA2926225A1 (en) | 2013-10-03 | 2015-04-09 | Takeda Vaccines, Inc. | Methods of detection and removal of rhabdoviruses from cell lines |
| CN103981084B (zh) * | 2014-05-29 | 2015-11-18 | 黑龙江省科学院微生物研究所 | 水中病毒分离提取装置及水中札幌病毒的提取方法 |
| JP6616329B2 (ja) * | 2015-01-09 | 2019-12-04 | タカラバイオ株式会社 | 非エンベロープウイルス粒子の製造方法 |
| JP6893174B2 (ja) * | 2015-01-16 | 2021-06-23 | タケダ ワクチン,インコーポレイテッド | 粒子に含まれる逆転写酵素活性の検出 |
| CN105907729B (zh) * | 2015-05-05 | 2019-08-16 | 广东东阳光药业有限公司 | 一种制备人乳头瘤病毒l1蛋白类病毒样颗粒的方法 |
| CN107034198B (zh) * | 2015-07-15 | 2021-03-09 | 长春百克生物科技股份公司 | 一种嵌合诺如病毒p颗粒及其制备和应用 |
| AU2016317661B2 (en) * | 2015-08-28 | 2023-05-18 | Ology Bioservices, Inc. | Norovirus vaccine |
| CN105779399A (zh) * | 2016-03-28 | 2016-07-20 | 广西壮族自治区林业科学研究院 | 一种昆虫杆状病毒纯化方法 |
| GB201614050D0 (en) * | 2016-08-17 | 2016-09-28 | Glaxosmithkline Ip Dev Ltd | Method for purifying viral vectors |
| BR112019004187A2 (pt) * | 2016-09-01 | 2019-06-25 | Takeda Pharmaceuticals Co | método para produzir um vírus enterovírus c, e, vírus enterovírus c. |
| EP3420076B1 (en) * | 2017-03-06 | 2024-02-21 | Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. | Methods of producing and characterizing virus vaccine and virus vaccine composition |
| ES2975182T3 (es) | 2017-03-06 | 2024-07-03 | Guangzhou Realbenefitspot Pharmaceutical Co Ltd | Métodos de producción y caracterización de vacunas víricas y composición de vacuna vírica |
| JP2021514391A (ja) | 2018-02-15 | 2021-06-10 | アイコン ジェネティクス ゲーエムベーハー | ノロウイルスに対する免疫応答を生成するための免疫原性組成物及びワクチン |
| CN108676781A (zh) * | 2018-05-18 | 2018-10-19 | 山东信得动物疫苗有限公司 | 一种重组禽流感病毒的工业化纯化方法 |
| CN111848749A (zh) * | 2018-05-23 | 2020-10-30 | 中国农业科学院兰州兽医研究所 | 猪细小病毒VLPs抗体检测试剂盒及其制备方法、应用 |
| ES2953232T3 (es) | 2019-03-12 | 2023-11-08 | Icon Genetics Gmbh | Partículas similares a norovirus con estabilidad mejorada |
| WO2021067389A1 (en) | 2019-09-30 | 2021-04-08 | Bioverativ Therapeutics Inc. | Lentiviral vector formulations |
| JP2024519800A (ja) | 2021-05-21 | 2024-05-21 | タケダ ワクチン,インコーポレイテッド | 固体組成物、フリーズドライ方法およびガラスバイアル |
| CA3224156A1 (en) * | 2021-06-28 | 2023-01-05 | VST LLC dba Medgene Labs | Sapovirus vaccines |
| CN116789773B (zh) * | 2022-11-30 | 2024-02-20 | 华北制药金坦生物技术股份有限公司 | 一种胞内表达病毒样颗粒的粗纯方法 |
| WO2025077800A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Products Co., Ltd. | Purification of norovirus virus-like particles (vlps) |
| CN118126202B (zh) * | 2024-05-07 | 2024-07-30 | 上海瑞宙生物科技有限公司 | 一种诺如病毒类病毒颗粒及其应用 |
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| JP2833106B2 (ja) | 1990-02-21 | 1998-12-09 | 株式会社島津製作所 | 液体クロマトグラフ |
| WO1994026087A2 (en) | 1993-05-14 | 1994-11-24 | Connor Kim C O | Recombinant protein production and insect cell culture and process |
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| AR004464A1 (es) | 1994-11-14 | 1998-12-16 | Merck Sharp & Dohme | Un metodo para producir una proteina de capside de papilomavirus |
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| US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
| DE69739268D1 (de) | 1996-11-08 | 2009-04-02 | Us Gov Health & Human Serv | Herstellung und reinigung von hepatitis c virus-ähnlichen partikeln |
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| DE19823814A1 (de) | 1998-05-27 | 1999-12-02 | Octapharma Ag Ziegelbruecke | Verfahren zur Trennung und/oder Isolierung von Plasmaproteinen mit annularer Chromatographie |
| PL347472A1 (en) | 1998-08-14 | 2002-04-08 | Merck & Co Inc | Process for purifying human papillomavirus virus-like particles |
| DE60040727D1 (de) * | 1999-02-05 | 2008-12-18 | Merck & Co Inc | Menschliche papillomavirus impfstoff-formulierungen |
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| DE10012732A1 (de) | 2000-03-18 | 2001-09-20 | Aventis Behring Gmbh | Thrombin-Zubereitungen und Verfahren zu ihrer Herstellung |
| JP2003066021A (ja) | 2001-08-28 | 2003-03-05 | Hiroshi Shionoya | 連続分取液体クロマトグラフィー装置とそれを用いる方法 |
| AU2003219760A1 (en) | 2002-02-14 | 2003-09-04 | Novavax, Inc. | Optimization of gene sequences of virus-like particles for expression in insect cells |
| US20060234226A1 (en) | 2002-04-26 | 2006-10-19 | Fahner Robert L | Non-affinity purification of proteins |
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| US8277819B2 (en) | 2005-06-16 | 2012-10-02 | Children's Hospital Medical Center | Norovirus particle for use as an antiviral or vaccine |
| EP1736538A1 (en) | 2005-06-21 | 2006-12-27 | Cytos Biotechnology AG | Process for the preparative purification of virus-like-particles (VLPs) |
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| EP2027875A1 (en) | 2007-08-23 | 2009-02-25 | Octapharma AG | A Process for Isolation and Purification of a Target Protein free of Prion Protein (PrPSC) |
| SG10201601660YA (en) | 2007-09-18 | 2016-04-28 | Takeda Vaccines Inc | Method of conferring a protective immune response to norovirus |
| EP2235165A1 (en) * | 2007-12-21 | 2010-10-06 | Cytos Biotechnology AG | Process for clarifying cell homogenates |
| KR102118458B1 (ko) | 2008-08-08 | 2020-06-03 | 다케다 백신즈 인코포레이티드 | 강화된 교차 반응성을 가진 복합체 캡시드 아미노산 서열들을 포함하는 바이러스-유사 입자들 |
| WO2010062757A1 (en) | 2008-11-03 | 2010-06-03 | Ligocyte Pharmaceuticals, Inc. | Improved methods for isolating enveloped virus-based vlps free of infectious agents |
| US8945895B2 (en) * | 2009-07-31 | 2015-02-03 | Baxter International Inc. | Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof |
| AU2011207355B2 (en) | 2010-01-21 | 2015-04-02 | Takeda Vaccines, Inc. | Targeted heterologous antigen presentation on Calicivirus virus-like particles |
| EP2619217B1 (en) | 2010-09-20 | 2016-11-09 | Bio-Rad Laboratories, Inc. | Dissociation of product-complexed contaminants in chromatography |
| FI122520B (fi) | 2010-10-15 | 2012-03-15 | Vesna Blazevic | Noroviruksen kapsidi ja rotaviruksen VP6-proteiini käytettäväksi yhdistelmärokotteena |
| CN102260651A (zh) * | 2011-06-24 | 2011-11-30 | 华中科技大学同济医学院附属协和医院 | 一种纯化病毒样颗粒蛋白的方法及其应用 |
| JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
| JP2015015931A (ja) | 2013-07-12 | 2015-01-29 | 株式会社Umnファーマ | ウイルス様粒子を含む培養物の製造方法 |
-
2013
- 2013-06-19 JO JOP/2013/0186A patent/JOP20130186B1/ar active
- 2013-06-21 TW TW102122276A patent/TWI647310B/zh active
- 2013-06-24 EP EP13807804.3A patent/EP2864478B1/en active Active
- 2013-06-24 AR ARP130102218 patent/AR091538A1/es active IP Right Grant
- 2013-06-24 UY UY0001034875A patent/UY34875A/es active IP Right Grant
- 2013-06-24 CN CN201380043618.XA patent/CN104583393A/zh active Pending
- 2013-06-24 CN CN202111173161.7A patent/CN114085273B/zh active Active
- 2013-06-24 SG SG10201610753YA patent/SG10201610753YA/en unknown
- 2013-06-24 WO PCT/US2013/047249 patent/WO2013192604A1/en not_active Ceased
- 2013-06-24 JP JP2015518633A patent/JP6553509B2/ja active Active
- 2013-06-24 AU AU2013277959A patent/AU2013277959B2/en active Active
- 2013-06-24 US US13/925,449 patent/US10167320B2/en active Active
- 2013-06-24 SG SG11201408459VA patent/SG11201408459VA/en unknown
- 2013-06-24 KR KR1020157001131A patent/KR102110876B1/ko active Active
- 2013-06-24 MX MX2014015842A patent/MX366234B/es active IP Right Grant
- 2013-06-24 CA CA2879815A patent/CA2879815A1/en active Pending
-
2015
- 2015-01-06 IN IN89DEN2015 patent/IN2015DN00089A/en unknown
-
2018
- 2018-11-27 US US16/201,073 patent/US11091519B2/en active Active
-
2021
- 2021-08-11 US US17/399,731 patent/US12286456B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| KR102110876B1 (ko) | 2020-05-14 |
| CN114085273B (zh) | 2024-07-12 |
| US11091519B2 (en) | 2021-08-17 |
| IN2015DN00089A (es) | 2015-05-29 |
| AU2013277959B2 (en) | 2019-05-16 |
| AR091538A1 (es) | 2015-02-11 |
| CA2879815A1 (en) | 2013-12-27 |
| SG11201408459VA (en) | 2015-01-29 |
| UY34875A (es) | 2013-12-31 |
| CN104583393A (zh) | 2015-04-29 |
| TW201406956A (zh) | 2014-02-16 |
| US10167320B2 (en) | 2019-01-01 |
| US20140004145A1 (en) | 2014-01-02 |
| HK1210210A1 (en) | 2016-04-15 |
| AU2013277959A1 (en) | 2015-01-22 |
| US20190169236A1 (en) | 2019-06-06 |
| US20220213147A1 (en) | 2022-07-07 |
| KR20150051988A (ko) | 2015-05-13 |
| WO2013192604A1 (en) | 2013-12-27 |
| SG10201610753YA (en) | 2017-02-27 |
| EP2864478A1 (en) | 2015-04-29 |
| EP2864478A4 (en) | 2015-12-02 |
| US12286456B2 (en) | 2025-04-29 |
| JP6553509B2 (ja) | 2019-07-31 |
| MX366234B (es) | 2019-07-03 |
| TWI647310B (zh) | 2019-01-11 |
| JOP20130186B1 (ar) | 2021-08-17 |
| EP2864478B1 (en) | 2020-12-09 |
| JP2015521628A (ja) | 2015-07-30 |
| CN114085273A (zh) | 2022-02-25 |
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