MX2014014769A - Pesario de cerclaje que contiene progesterona de liberacion prolongada, sostenida y continua, util para la prevencion de parto prematuro. - Google Patents
Pesario de cerclaje que contiene progesterona de liberacion prolongada, sostenida y continua, util para la prevencion de parto prematuro.Info
- Publication number
- MX2014014769A MX2014014769A MX2014014769A MX2014014769A MX2014014769A MX 2014014769 A MX2014014769 A MX 2014014769A MX 2014014769 A MX2014014769 A MX 2014014769A MX 2014014769 A MX2014014769 A MX 2014014769A MX 2014014769 A MX2014014769 A MX 2014014769A
- Authority
- MX
- Mexico
- Prior art keywords
- pessary
- progesterone
- sustained
- cerclage
- prevent premature
- Prior art date
Links
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 title abstract 10
- 229960003387 progesterone Drugs 0.000 title abstract 5
- 239000000186 progesterone Substances 0.000 title abstract 5
- 208000005107 Premature Birth Diseases 0.000 title abstract 2
- 206010036590 Premature baby Diseases 0.000 title abstract 2
- 230000002035 prolonged effect Effects 0.000 title abstract 2
- 230000002459 sustained effect Effects 0.000 title abstract 2
- 229920000642 polymer Polymers 0.000 abstract 3
- 229920001971 elastomer Polymers 0.000 abstract 2
- 239000000806 elastomer Substances 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- -1 dimethylsiloxane Chemical class 0.000 abstract 1
- 238000004073 vulcanization Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Reproductive Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Biological Depolymerization Polymers (AREA)
Abstract
Pesario de cerclaje que contiene progesterona distribuida homogéneamente en el cuerpo del pesario proporcionando una liberación prolongada, sostenida y continua, por un periodo de al menos 6 meses, donde el pesario está formado por elastómeros de dimetilsiloxano con mecanismo RTV (Room Temperature Vulcanization), la cantidad de progesterona está comprendida entre 20% a 30% p/p, respecto al peso del pesario y las proporciones de los polímeros que forman la matriz, se encuentra entre 6:1 a 14:1. El pesario de cerclaje es útil para la prevención de parto prematuro. La progesterona difunde a través del polímero en forma continua, sin alterar la forma e integridad del pesario, dado que el elastómero que forma la matriz polimérica utilizado en la presente invención, no es biodegradable. Esto garantiza que la forma del pesario se conserve intacta hasta el término de tratamiento.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2014/062691 WO2015198104A1 (es) | 2014-06-28 | 2014-06-28 | Pesario de cerclaje que contiene progesterona de liberación prolongada, sostenida y continua, útil para la prevención de parto prematuro |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014014769A true MX2014014769A (es) | 2016-03-30 |
| MX368212B MX368212B (es) | 2019-09-24 |
Family
ID=54937437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014014769A MX368212B (es) | 2014-06-28 | 2014-06-28 | Pesario de cerclaje que contiene progesterona de liberación prolongada, sostenida y continua, útil para la prevención de parto prematuro. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9820994B2 (es) |
| EP (1) | EP2982352B1 (es) |
| JP (1) | JP6529583B2 (es) |
| KR (1) | KR20170021929A (es) |
| CN (1) | CN105392454B (es) |
| AR (2) | AR098604A1 (es) |
| BR (1) | BR112014030232A2 (es) |
| CA (1) | CA2873222A1 (es) |
| CR (1) | CR20160604A (es) |
| CY (1) | CY1121245T1 (es) |
| DK (1) | DK2982352T3 (es) |
| ES (1) | ES2699003T3 (es) |
| HR (1) | HRP20181794T1 (es) |
| HU (1) | HUE040176T2 (es) |
| LT (1) | LT2982352T (es) |
| MX (1) | MX368212B (es) |
| PL (1) | PL2982352T3 (es) |
| PT (1) | PT2982352T (es) |
| SI (1) | SI2982352T1 (es) |
| WO (1) | WO2015198104A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102110132B1 (ko) * | 2017-10-27 | 2020-05-13 | 고려대학교산학협력단 | 자궁경부 무력증에서 조산을 방지하기 위한 자궁경부 밴드 구조체 |
| US11497647B2 (en) | 2018-04-24 | 2022-11-15 | Emory University | Anatomical support systems, devices, and related methods |
| US11311409B2 (en) | 2018-05-19 | 2022-04-26 | Ashley Camille CRAFTON | Hannah cervical cup |
| US12011602B2 (en) | 2019-06-18 | 2024-06-18 | Obstetric Solutions Llc | Wireless power for pessary device |
| US11872395B2 (en) | 2019-06-18 | 2024-01-16 | Obstetric Solutions, Llc | Pessary device and methods for preventing premature births |
| CN110767057B (zh) * | 2019-11-02 | 2025-01-24 | 上海市第一妇婴保健院 | 一种逼真度高、可拆卸的宫颈环扎术模拟教学模型及教学方法 |
| EP4069248A4 (en) * | 2019-12-06 | 2024-01-03 | Prathima Chowdary | SUSTAINED RELEASE VAGINAL RING PESSARY FOR TREATMENT OF ATROPHY, CYSTITIS AND UTEROVAGINAL PROLAPSUS |
| KR102571791B1 (ko) * | 2021-03-22 | 2023-08-28 | 가톨릭대학교 산학협력단 | 산모 맞춤형 조산 예방용 페서리 및 이의 제조방법 |
| KR20250177790A (ko) | 2024-06-17 | 2025-12-24 | 주식회사 포피랩 | 질 페서리 장치 |
| CN119655843B (zh) * | 2024-12-06 | 2025-11-07 | 天海佳合医疗器械(苏州)有限公司 | 一种延迟早产装置 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US415991A (en) | 1889-11-26 | zipernowsky | ||
| US3948254A (en) * | 1971-11-08 | 1976-04-06 | Alza Corporation | Novel drug delivery device |
| BE791632A (fr) * | 1971-11-20 | 1973-05-21 | Schering Ag | Supports a base de caoutchouc siliconique pour agents medicamenteux |
| EG11114A (en) * | 1973-12-06 | 1977-01-31 | Schering Ag | Dispositif contraceptif intra-uterin |
| DE2445971A1 (de) * | 1974-09-24 | 1976-04-08 | Schering Ag | Arzneimittelwirkstofftraeger ii |
| US4439432A (en) * | 1982-03-22 | 1984-03-27 | Peat Raymond F | Treatment of progesterone deficiency and related conditions with a stable composition of progesterone and tocopherols |
| JP2590358B2 (ja) * | 1988-03-01 | 1997-03-12 | 正雄 五十嵐 | 子宮内膜症治療用の子宮内又は膣内投与製剤 |
| GB9326255D0 (en) * | 1993-12-23 | 1994-02-23 | Roussel Lab Ltd | Medical device for the prevention and treatment of cancer |
| DE19606355A1 (de) * | 1996-02-12 | 1997-08-14 | Schering Ag | Kontrazeptive Freisetzungssysteme mit antiviraler und/oder antibakterieller Wirkung |
| FR2745180B1 (fr) * | 1996-02-23 | 1998-05-07 | Dow Corning Sa | Procede de fabrication de dispositifs a liberation controlee |
| US5869081A (en) | 1996-06-28 | 1999-02-09 | The Population Council | Progesterone vaginal ring for treatment of infertility |
| US5972372A (en) * | 1996-07-31 | 1999-10-26 | The Population Council, Inc. | Intravaginal rings with insertable drug-containing core |
| AU741482B2 (en) * | 1997-05-07 | 2001-11-29 | Allergan Pharmaceuticals International Limited | Intravaginal drug delivery devices for the administration of testosterone and testosterone precursors |
| AU1300799A (en) | 1997-11-03 | 1999-05-24 | Deschutes Medical Products, Inc. | Pessary with medicated cartridge |
| US6476079B1 (en) * | 1999-12-23 | 2002-11-05 | Leiras Oy | Devices for the delivery of drugs having antiprogestinic properties |
| US20050197651A1 (en) * | 2001-04-25 | 2005-09-08 | Chen Hai L. | Vaginal ring preparation and its application |
| US20040089308A1 (en) | 2002-11-13 | 2004-05-13 | Welch Robert A. | Cervical ring to deliver medication |
| US7833545B2 (en) | 2003-04-29 | 2010-11-16 | The General Hospital Corporation | Methods and devices for the sustained release of multiple drugs |
| AU2005265357B2 (en) | 2004-07-09 | 2011-04-07 | Laboratoire Hra Pharma | Sustained release compositions containing progesterone receptor modulators |
| US8828981B2 (en) | 2007-02-06 | 2014-09-09 | George Creasy | Progesterone for the treatment or prevention of spontaneous preterm birth |
| KR20140048321A (ko) * | 2008-02-04 | 2014-04-23 | 테바 위민즈 헬스 인코포레이티드 | 프로게스테론 함유 단일형 질내 링 및 그의 제조방법과 용도 |
| FI20085277A0 (fi) * | 2008-04-02 | 2008-04-02 | Bayer Schering Pharma Oy | Kohdunsisäinen järjestelmä |
| DK2456421T3 (en) | 2009-07-21 | 2017-06-06 | The Population Council Inc | VAGINAL RING consisting of multiple layers with gradient |
| CA2798034A1 (en) * | 2010-03-28 | 2011-10-13 | Evestra, Inc. | Intravaginal drug delivery device |
| US8580294B2 (en) * | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
| CN103747765B (zh) | 2011-06-06 | 2016-04-06 | 橡冠科学研究院 | 采用芯吸释放窗口的药物递送装置 |
| AR089765A1 (es) * | 2012-01-23 | 2014-09-17 | Bayer Oy | Un sistema para el suministro de un farmaco |
| DE102012009057A1 (de) | 2012-05-09 | 2013-11-14 | Dr. Arabin GmbH & Co. KG | Rotationspessar mit zusätzlicher Wirkstoffkomponente |
-
2014
- 2014-06-28 WO PCT/IB2014/062691 patent/WO2015198104A1/es not_active Ceased
- 2014-06-28 KR KR1020147034262A patent/KR20170021929A/ko not_active Ceased
- 2014-06-28 EP EP14802800.4A patent/EP2982352B1/en not_active Not-in-force
- 2014-06-28 SI SI201430975T patent/SI2982352T1/sl unknown
- 2014-06-28 CA CA2873222A patent/CA2873222A1/en not_active Abandoned
- 2014-06-28 HU HUE14802800A patent/HUE040176T2/hu unknown
- 2014-06-28 CN CN201480001890.6A patent/CN105392454B/zh not_active Expired - Fee Related
- 2014-06-28 ES ES14802800T patent/ES2699003T3/es active Active
- 2014-06-28 US US14/405,037 patent/US9820994B2/en not_active Expired - Fee Related
- 2014-06-28 PT PT14802800T patent/PT2982352T/pt unknown
- 2014-06-28 LT LTEP14802800.4T patent/LT2982352T/lt unknown
- 2014-06-28 HR HRP20181794TT patent/HRP20181794T1/hr unknown
- 2014-06-28 DK DK14802800.4T patent/DK2982352T3/en active
- 2014-06-28 MX MX2014014769A patent/MX368212B/es active IP Right Grant
- 2014-06-28 BR BR112014030232A patent/BR112014030232A2/pt not_active Application Discontinuation
- 2014-06-28 PL PL14802800T patent/PL2982352T3/pl unknown
- 2014-06-28 CR CR20160604A patent/CR20160604A/es unknown
- 2014-06-28 JP JP2017520021A patent/JP6529583B2/ja not_active Expired - Fee Related
- 2014-12-03 AR ARP140104501A patent/AR098604A1/es unknown
-
2018
- 2018-12-03 CY CY20181101285T patent/CY1121245T1/el unknown
-
2020
- 2020-01-22 AR ARP200100164A patent/AR122434A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2982352A1 (en) | 2016-02-10 |
| ES2699003T3 (es) | 2019-02-06 |
| BR112014030232A2 (pt) | 2017-06-27 |
| CY1121245T1 (el) | 2020-05-29 |
| AR098604A1 (es) | 2016-06-01 |
| DK2982352T3 (en) | 2018-11-26 |
| CN105392454B (zh) | 2018-05-08 |
| HRP20181794T1 (hr) | 2018-12-28 |
| HUE040176T2 (hu) | 2019-02-28 |
| EP2982352A4 (en) | 2017-06-14 |
| LT2982352T (lt) | 2018-11-12 |
| CA2873222A1 (en) | 2015-12-28 |
| JP2017524030A (ja) | 2017-08-24 |
| CN105392454A (zh) | 2016-03-09 |
| SI2982352T1 (sl) | 2018-12-31 |
| PL2982352T3 (pl) | 2019-01-31 |
| WO2015198104A1 (es) | 2015-12-30 |
| AR122434A2 (es) | 2022-09-14 |
| US20160250229A1 (en) | 2016-09-01 |
| US9820994B2 (en) | 2017-11-21 |
| MX368212B (es) | 2019-09-24 |
| KR20170021929A (ko) | 2017-03-02 |
| PT2982352T (pt) | 2018-11-29 |
| CR20160604A (es) | 2017-03-10 |
| EP2982352B1 (en) | 2018-10-03 |
| JP6529583B2 (ja) | 2019-06-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or rights |
Owner name: LABORATORIOS ANDROMACO, S.A. (EX INVERSIONES GRUCH |
|
| FG | Grant or registration |