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MX2014011324A - Metodos para el tratamiento del cancer utilizando inhibidores de la cinasa aurora. - Google Patents

Metodos para el tratamiento del cancer utilizando inhibidores de la cinasa aurora.

Info

Publication number
MX2014011324A
MX2014011324A MX2014011324A MX2014011324A MX2014011324A MX 2014011324 A MX2014011324 A MX 2014011324A MX 2014011324 A MX2014011324 A MX 2014011324A MX 2014011324 A MX2014011324 A MX 2014011324A MX 2014011324 A MX2014011324 A MX 2014011324A
Authority
MX
Mexico
Prior art keywords
methods
treating cancer
kinase inhibitors
aurora kinase
treatment
Prior art date
Application number
MX2014011324A
Other languages
English (en)
Other versions
MX358411B (es
Inventor
Arijit Chakravarty
Jeffrey A Ecsedy
Robert W Kleinfield
Kha N Le
Wen Chyi Shyu
Karthik Venkatakrishnan
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Publication of MX2014011324A publication Critical patent/MX2014011324A/es
Publication of MX358411B publication Critical patent/MX358411B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se divulgan métodos para el tratamiento de varios trastornos proliferativos de células. En particular, los métodos divulgados para el tratamiento de varios trastornos proliferativos de células mediante la administración de un inhibidor selectivo de la cinasa Aurora A en combinación con quimioterapia a base de taxano, tal como paclitaxel o docetaxel.
MX2014011324A 2012-03-20 2013-03-19 Uso de un inhiboidor de aurora quinasa y paclitaxel para el tratamiento de cáncer de pulmón. MX358411B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261613258P 2012-03-20 2012-03-20
PCT/US2013/032962 WO2013142491A1 (en) 2012-03-20 2013-03-19 Methods of treating cancer using aurora kinase inhibitors

Publications (2)

Publication Number Publication Date
MX2014011324A true MX2014011324A (es) 2014-12-05
MX358411B MX358411B (es) 2018-08-20

Family

ID=48048255

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014011324A MX358411B (es) 2012-03-20 2013-03-19 Uso de un inhiboidor de aurora quinasa y paclitaxel para el tratamiento de cáncer de pulmón.

Country Status (24)

Country Link
US (2) US20130303519A1 (es)
EP (1) EP2827855B1 (es)
JP (1) JP6373252B2 (es)
KR (1) KR102128866B1 (es)
CN (1) CN104271129A (es)
AU (1) AU2013235275B2 (es)
CA (1) CA2868024A1 (es)
EA (1) EA036434B1 (es)
ES (1) ES2746946T3 (es)
GE (2) GEAP201813599A (es)
IL (1) IL234686B (es)
IN (1) IN2014DN08477A (es)
JO (1) JO3630B1 (es)
MA (1) MA37438A1 (es)
MX (1) MX358411B (es)
MY (1) MY175225A (es)
NZ (1) NZ700744A (es)
PH (1) PH12014502109A1 (es)
SG (2) SG11201405621UA (es)
TN (1) TN2014000387A1 (es)
TW (1) TWI649082B (es)
UA (1) UA117455C2 (es)
WO (1) WO2013142491A1 (es)
ZA (1) ZA201407551B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
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WO2017003845A1 (en) * 2015-07-02 2017-01-05 Millennium Pharmaceuticals, Inc. Biomarkers of response to selective inhibitors of aurora a kinase
CN110833544B (zh) * 2018-08-17 2022-08-09 深圳微芯生物科技股份有限公司 组蛋白去乙酰化酶抑制剂与蛋白激酶抑制剂之组合及其制药用途

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Also Published As

Publication number Publication date
TW201343169A (zh) 2013-11-01
CA2868024A1 (en) 2013-09-26
GEAP201813599A (en) 2018-06-25
EP2827855B1 (en) 2019-06-26
EP2827855A1 (en) 2015-01-28
NZ700744A (en) 2016-09-30
AU2013235275A1 (en) 2014-10-23
UA117455C2 (uk) 2018-08-10
MY175225A (en) 2020-06-16
ZA201407551B (en) 2019-01-30
KR102128866B1 (ko) 2020-07-01
SG10201607741RA (en) 2016-11-29
KR20140144215A (ko) 2014-12-18
AU2013235275B2 (en) 2017-12-07
US10213436B2 (en) 2019-02-26
WO2013142491A1 (en) 2013-09-26
TN2014000387A1 (en) 2015-12-21
TWI649082B (zh) 2019-02-01
EA036434B1 (ru) 2020-11-10
GEP20186900B (en) 2018-10-10
MX358411B (es) 2018-08-20
JP2015510945A (ja) 2015-04-13
EA201491727A1 (ru) 2015-01-30
PH12014502109A1 (en) 2014-12-10
HK1206253A1 (en) 2016-01-08
IN2014DN08477A (es) 2015-05-08
IL234686A0 (en) 2014-11-30
US20160193224A1 (en) 2016-07-07
CN104271129A (zh) 2015-01-07
SG11201405621UA (en) 2014-10-30
ES2746946T3 (es) 2020-03-09
MA37438A1 (fr) 2016-05-31
JO3630B1 (ar) 2020-08-27
IL234686B (en) 2020-01-30
JP6373252B2 (ja) 2018-08-15
US20130303519A1 (en) 2013-11-14

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