[go: up one dir, main page]

MX2014011181A - Microemulsiones basadas en ciclodextrina y usos dermatologicos de las mismas. - Google Patents

Microemulsiones basadas en ciclodextrina y usos dermatologicos de las mismas.

Info

Publication number
MX2014011181A
MX2014011181A MX2014011181A MX2014011181A MX2014011181A MX 2014011181 A MX2014011181 A MX 2014011181A MX 2014011181 A MX2014011181 A MX 2014011181A MX 2014011181 A MX2014011181 A MX 2014011181A MX 2014011181 A MX2014011181 A MX 2014011181A
Authority
MX
Mexico
Prior art keywords
cyclodextrin
based microemulsions
dermatological uses
microemulsions
skin
Prior art date
Application number
MX2014011181A
Other languages
English (en)
Inventor
Mark W Trumbore
Pinaki Ranjan Majhi
Dinen Divyang Shah
Original Assignee
Prec Dermatology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prec Dermatology Inc filed Critical Prec Dermatology Inc
Publication of MX2014011181A publication Critical patent/MX2014011181A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/068—Microemulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/738—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

En la presente invención se refiere a sistemas de microemulsión estabilizada con ciclodextrina útiles para incrementar la solubilidad, estabilidad, biodisponibilidad o seguridad de un agente activo para el suministro a la piel. Las microemulsiones pueden reducir la aparición de irritación de la piel u olor con la aplicación.
MX2014011181A 2012-03-22 2013-03-14 Microemulsiones basadas en ciclodextrina y usos dermatologicos de las mismas. MX2014011181A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261614177P 2012-03-22 2012-03-22
PCT/US2013/031296 WO2013142249A1 (en) 2012-03-22 2013-03-14 Cyclodextrin-based microemulsions, and dermatological uses thereof

Publications (1)

Publication Number Publication Date
MX2014011181A true MX2014011181A (es) 2015-03-06

Family

ID=49212005

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014011181A MX2014011181A (es) 2012-03-22 2013-03-14 Microemulsiones basadas en ciclodextrina y usos dermatologicos de las mismas.

Country Status (10)

Country Link
US (3) US9018236B2 (es)
EP (1) EP2827842A4 (es)
JP (1) JP2015510934A (es)
KR (1) KR20140134712A (es)
CN (1) CN104363893A (es)
AU (1) AU2013235483A1 (es)
BR (1) BR112014023379A8 (es)
CA (1) CA2867877A1 (es)
MX (1) MX2014011181A (es)
WO (3) WO2013142249A1 (es)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
EP1556009B2 (en) 2002-10-25 2021-07-21 Foamix Pharmaceuticals Ltd. Cosmetic and pharmaceutical foam
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
US20120087872A1 (en) 2009-04-28 2012-04-12 Foamix Ltd. Foamable Vehicles and Pharmaceutical Compositions Comprising Aprotic Polar Solvents and Uses Thereof
WO2011013008A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
US10029013B2 (en) 2009-10-02 2018-07-24 Foamix Pharmaceuticals Ltd. Surfactant-free, water-free formable composition and breakable foams and their uses
PL2758037T3 (pl) 2011-09-23 2018-10-31 Emerald Hilton Davis, Llc Samoistnie złożona cząsteczka nanostrukturalna i sposób otrzymywania
US10988618B2 (en) 2011-09-23 2021-04-27 Dystar Hilton Davis Corp. Self-assembled nano-structured particle and methods for preparing
CA2936430C (en) * 2014-02-14 2022-05-31 Mission Pharmacal Company Sprayable composition containing zinc oxide and a fluoro-olefin propellant
US9381156B2 (en) 2014-02-14 2016-07-05 Mission Pharmacal Company Stabilized, sprayable emulsion containing active agent particles
CA2936409C (en) 2014-02-14 2023-03-14 Mission Pharmacal Company Spray delivery device
GB2525894A (en) 2014-05-07 2015-11-11 Boots Co Plc Skin care composition
GB2525895A (en) * 2014-05-07 2015-11-11 Boots Co Plc Skin care composition
MX2017013949A (es) 2015-04-29 2018-11-09 Silk Therapeutics Inc Composiciones mectantes a base de seda y sus metodos.
CA2997220A1 (en) * 2015-09-03 2017-03-09 Delivra Inc. Transdermal formulations for delivery of doxycycline, and their use in the treatment of doxycycline-responsive diseases and conditions
CN108348456B (zh) 2015-10-30 2021-09-17 亭铂医药有限责任公司 异维甲酸制剂及其用途和方法
EP3466406A4 (en) * 2016-05-24 2020-01-01 Natura Cosméticos S.A. ANTI-SPOT COSMETIC COMPOSITION, COMPOSITION SYSTEM AND METHOD FOR COSMETIC TREATMENT OF THE SKIN
WO2017201596A1 (pt) 2016-05-24 2017-11-30 Natura Cosméticos S.A. Composição cosmética antissinais, sistema de composições e método para tratamento cosmético da pele
ES2929765T3 (es) * 2016-07-28 2022-12-01 Honeywell Int Inc Composiciones propulsoras y de autoprotección
CN109689829A (zh) * 2016-07-28 2019-04-26 霍尼韦尔国际公司 推进剂和乳化组合物
MX2020012139A (es) 2016-09-08 2021-01-29 Vyne Pharmaceuticals Inc Composiciones y metodos para tratar rosacea y acne.
AU2017397235B2 (en) 2017-01-31 2023-09-21 Kimberly-Clark Worldwide, Inc. Antibacterial composition including benzoic acid ester and methods of inhibiting bacterial growth utilizing the same
CN106943348B (zh) * 2017-03-29 2020-02-07 甘肃新天马制药股份有限公司 一种乳酸依沙吖啶油膜剂及其制备方法
KR102359439B1 (ko) * 2017-03-31 2022-02-09 (주)아모레퍼시픽 벤조산아마이드 화합물 및 사이클로덱스트린 용해보조제를 포함하는 조성물
US10076484B1 (en) * 2017-05-01 2018-09-18 Robert Baron Formulation and method of conditioning skin and preserving cosmetics applied thereto
JP2020158493A (ja) * 2019-03-20 2020-10-01 ジャパンメディック株式会社 パンテノールを含有する油中水型（ｗ／ｏ型）クリーム
ES2765513A1 (es) * 2019-05-10 2020-06-09 Llorca Manuel Asin Composicion para aumentar la solubilidad de compuestos
CN112294693B (zh) * 2019-07-26 2021-07-20 珀莱雅化妆品股份有限公司 一种视黄醇及其衍生物的超分子制剂及其制备方法
CN110423264B (zh) * 2019-08-26 2020-12-01 中国科学院长春应用化学研究所 一种基于活化酯高效制备棕榈酰三肽-5的方法
US12485071B2 (en) 2020-05-09 2025-12-02 Conopco, Inc. Personal care composition with visually distinct aqueous and oil phase
US12478564B2 (en) 2020-05-09 2025-11-25 Conopco, Inc. Personal care composition with visually distinct aqueous and oil phase
CN112107506B (zh) * 2020-09-30 2023-03-28 广州市科能化妆品科研有限公司 视黄醇类包裹物及其制备方法和应用
JP2024514050A (ja) * 2021-04-16 2024-03-28 ディーエスエム アイピー アセッツ ビー．ブイ． レチノール製剤（ｉ）
US20220362130A1 (en) * 2021-04-30 2022-11-17 L'oreal Compositions and methods for treating keratin fibers
CA3237578A1 (en) * 2021-11-19 2023-05-25 Pg13 Launchpad Alpha, Inc. Dba Kindra Formulations and methods for treating symptoms of menopause
JP2024541369A (ja) * 2021-11-29 2024-11-08 ザ プロクター アンド ギャンブル カンパニー スキンケア組成物
CN114869797B (zh) * 2022-03-22 2023-07-21 深圳市美莲达生物科技有限公司 含有视黄醇和黄精多糖的精华液及其应用
JP2024145418A (ja) * 2023-03-31 2024-10-15 ハウス食品グループ本社株式会社 標的成分の阻害剤
PL248326B1 (pl) * 2023-10-23 2025-11-24 Politechnika Gdanska Kompozycja transdermalna mikroemulsji
CN117462451B (zh) * 2023-12-28 2024-04-02 拉芳家化股份有限公司 一种含抗真菌剂的组合物以及制备与应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5472954A (en) * 1992-07-14 1995-12-05 Cyclops H.F. Cyclodextrin complexation
DE19713092A1 (de) * 1997-03-27 1998-10-01 Wacker Chemie Gmbh Komplexe aus Gamma-Cyclodextrin und Retinol bzw. Retinol-Derivaten sowie Verfahren zu ihrer Herstellung und ihre Verwendung
IT1291362B1 (it) * 1997-05-13 1999-01-07 Vectorpharma Int Composizioni farmaceutiche multicomponente bifasiche contenenti sostanze atte a modificare la partizione dei principi attivi
US7465460B1 (en) * 1999-06-23 2008-12-16 Dennis Gross Composition of low viscosity and method for treating skin
US7919113B2 (en) * 1999-12-30 2011-04-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Dispersible concentrate lipospheres for delivery of active agents
US6444214B1 (en) 2000-05-04 2002-09-03 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
DE10151245A1 (de) * 2001-10-17 2003-05-15 Beiersdorf Ag Kosmetische und/oder dermatologische Wirkstoffkombination
ITMI20032019A1 (it) * 2003-10-17 2005-04-18 Fidia Farmaceutici Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono
US20050191343A1 (en) * 2003-11-26 2005-09-01 Shire Laboratories, Inc. Micellar systems useful for delivery of lipophilic or hydrophobic compounds
US20050266085A1 (en) * 2004-05-28 2005-12-01 Warner Kevin S Gelled emulsion and microemulsion formulations for dermal drug delivery
JP2006029981A (ja) * 2004-07-15 2006-02-02 Taisho Pharmaceut Co Ltd 感冒薬配合成分の分析方法及び分析用泳動液
CA2548532C (en) * 2004-09-27 2014-12-02 Jan De Rijk Methods and compositions for treatment of water
MX2007007457A (es) * 2004-12-21 2007-08-20 Honeywell Int Inc Compuestos estabilizados de yodocarbono.
WO2009007785A2 (en) 2006-11-14 2009-01-15 Foamix Ltd. Stable non-alcoholic foamable pharmaceutical emulsion compositions with an unctuous emollient and their uses
EP2164575A2 (en) * 2007-06-01 2010-03-24 Galderma Research & Development Skin moisturizer and use thereof
FR2920967B1 (fr) * 2007-09-14 2009-10-23 Sederma Soc Par Actions Simpli Utilisation de l'hydroxymethionine en tant qu'actif anti age
US8652443B2 (en) * 2008-02-14 2014-02-18 Precision Dermatology, Inc. Foamable microemulsion compositions for topical administration
FR2939698B1 (fr) * 2008-12-12 2011-01-21 Univ Lille Ii Droit & Sante Procede de fabrication d'une formulation et utilisation pour la delivrance de medicaments polaires
US9084902B2 (en) * 2010-06-30 2015-07-21 Mcneil-Ppc, Inc. Non-alchohol bioactive essential oil mouth rinses
CN102106819A (zh) * 2010-12-29 2011-06-29 中国药科大学 药物-环糊精包合物自微乳组合物的制备方法及应用

Also Published As

Publication number Publication date
WO2013142247A1 (en) 2013-09-26
US20130253015A1 (en) 2013-09-26
JP2015510934A (ja) 2015-04-13
EP2827842A1 (en) 2015-01-28
EP2827842A4 (en) 2015-12-16
BR112014023379A2 (es) 2017-06-20
US20130253014A1 (en) 2013-09-26
WO2013142249A1 (en) 2013-09-26
CN104363893A (zh) 2015-02-18
WO2013142251A1 (en) 2013-09-26
KR20140134712A (ko) 2014-11-24
CA2867877A1 (en) 2013-09-26
US20130251644A1 (en) 2013-09-26
AU2013235483A1 (en) 2014-10-09
BR112014023379A8 (pt) 2017-07-25
US9018236B2 (en) 2015-04-28

Similar Documents

Publication Publication Date Title
MX2014011181A (es) Microemulsiones basadas en ciclodextrina y usos dermatologicos de las mismas.
AU2018256640A1 (en) Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives
WO2015023649A3 (en) Peptides for enhancing transdermal delivery
UA109785C2 (uk) Композиція фармацевтичного аерозолю, яка включає аналог вітаміну d і кортикостероїд
MX2015008627A (es) Derivados de acido boronico y usos terapeuticos de los mismos.
IN2014MN02213A (es)
PH12015502539B1 (en) Cenicriviroc compositions and methods of making and using the same
EP4360621A3 (en) Formulations of bendamustine
MX2018002462A (es) Una composicion farmaceutica para reducir la grasa localizada y sus usos.
MY193312A (en) Topical formulation for promoting wound healing
WO2013114371A8 (en) Dry powder formulations of dnase i
SG10201803430SA (en) Stable formulation of insulin glulisine
IN2014MN01470A (es)
EP3513789A3 (en) Prophylactic and therapeutic agents for fgfr3 diseases
IN2014MN02236A (es)
CA3010568A1 (en) Oromucosal nanofiber carriers for therapeutic treatment
MX363699B (es) Producto de comicronizacion que comprende acetato de ulipristal.
WO2016030899A8 (en) Methods of treating amyotrophic lateral scleroses
MX2016001422A (es) Composicion farmaceutica de fingolimod.
FR2969924B1 (fr) Composition comprenant un phosphate de tocopherol
MX2014014579A (es) Composiciones farmaceuticas topicas de tipo emulsion aceite en agua que contienen un retinoide.
GB201204632D0 (en) Delivery system
MX2013012038A (es) Combinacion de carotenoide, fitoestrogeno y vitamina c para la humectacion de la piel.
WO2012130642A3 (en) Skin care composition
MX2020005682A (es) Extracto de helichrysum gymnocephalum para el tratamiento y/o la prevencion de dermatosis inflamatorias.