MX2014007897A - Nuevos derivados de azetidina, composiciones farmaceuticas y sus usos. - Google Patents
Nuevos derivados de azetidina, composiciones farmaceuticas y sus usos.Info
- Publication number
- MX2014007897A MX2014007897A MX2014007897A MX2014007897A MX2014007897A MX 2014007897 A MX2014007897 A MX 2014007897A MX 2014007897 A MX2014007897 A MX 2014007897A MX 2014007897 A MX2014007897 A MX 2014007897A MX 2014007897 A MX2014007897 A MX 2014007897A
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutical compositions
- azetidine derivatives
- new azetidine
- new
- derivatives
- Prior art date
Links
- 150000001539 azetidines Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
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- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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Abstract
La invención se refiere a nuevos derivados de azetidina de la fórmula I (ver Fórmula) a su uso como medicamentos, a métodos para su uso terapéutico y a composiciones farmacéuticas que los contienen.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11196170 | 2011-12-30 | ||
| PCT/EP2012/077027 WO2013098375A1 (en) | 2011-12-30 | 2012-12-28 | New azetidine derivatives, pharmaceutical compositions and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2014007897A true MX2014007897A (es) | 2014-09-25 |
Family
ID=47553036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014007897A MX2014007897A (es) | 2011-12-30 | 2012-12-28 | Nuevos derivados de azetidina, composiciones farmaceuticas y sus usos. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8623860B2 (es) |
| EP (1) | EP2797884B1 (es) |
| JP (1) | JP6130399B2 (es) |
| KR (1) | KR20140115307A (es) |
| CN (1) | CN104093705A (es) |
| AU (1) | AU2012360797A1 (es) |
| BR (1) | BR112014015845A8 (es) |
| CA (1) | CA2861013A1 (es) |
| EA (1) | EA201400771A1 (es) |
| IL (1) | IL232914A0 (es) |
| MX (1) | MX2014007897A (es) |
| PH (1) | PH12014501514A1 (es) |
| WO (1) | WO2013098375A1 (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140033377A (ko) | 2011-05-10 | 2014-03-18 | 길리애드 사이언시즈, 인코포레이티드 | 나트륨 채널 조절제로서의 융합된 헤테로시클릭 화합물 |
| UY34171A (es) | 2011-07-01 | 2013-01-31 | Gilead Sciences Inc | Compuestos heterocíclicos fusionados como moduladores del canal iónico |
| NO3175985T3 (es) | 2011-07-01 | 2018-04-28 | ||
| WO2014061693A1 (ja) * | 2012-10-17 | 2014-04-24 | 塩野義製薬株式会社 | 新規非芳香族炭素環又は非芳香族複素環誘導体 |
| WO2015036892A1 (en) | 2013-09-12 | 2015-03-19 | Pfizer Inc. | Use of acetyl-coa carboxylase inhibitors for treating acne vulgaris |
| CN103483273B (zh) * | 2013-09-12 | 2015-11-25 | 浙江工业大学 | 6-甲基-5-氟-2,4-嘧啶二胺类化合物及其制备与应用 |
| WO2015056782A1 (ja) | 2013-10-17 | 2015-04-23 | 塩野義製薬株式会社 | 新規アルキレン誘導体 |
| AU2015229117A1 (en) | 2014-03-13 | 2016-09-29 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for increasing CFTR activity |
| WO2015138909A1 (en) | 2014-03-13 | 2015-09-17 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for increasing cftr activity |
| CA2952862A1 (en) | 2014-06-19 | 2015-12-23 | Proteostasis Therapeutics, Inc. | Compounds, compositions and methods of increasing cftr activity |
| WO2016105477A1 (en) | 2014-12-23 | 2016-06-30 | Proteostasis Therapeutics, Inc | Derivatives of 5-phenyl- or 5-heteroarylthiazol-2-carboxylic amide useful for the treatment of inter alia cystic fibrosis |
| MA41253A (fr) | 2014-12-23 | 2017-10-31 | Proteostasis Therapeutics Inc | Composés, compositions et procédés pour augmenter l'activité du cftr |
| WO2016105484A1 (en) | 2014-12-23 | 2016-06-30 | Proteostasis Therapeutics, Inc. | Derivatives of 5-(hetero)arylpyrazol-3-carboxylic amide or 1-(hetero)aryltriazol-4-carboxylic amide useful for the treatment of inter alia cystic fibrosis |
| US10344023B2 (en) | 2014-12-23 | 2019-07-09 | Proteostasis Therapeutics, Inc. | Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis |
| EP3325474A1 (en) | 2015-07-24 | 2018-05-30 | Proteostasis Therapeutics, Inc. | Compounds, compositions and methods of increasing cftr activity |
| BR112018007021B1 (pt) | 2015-10-06 | 2024-01-09 | Proteostasis Therapeutics, Inc | Composto, composição compreendendo os ditos compostos e uso dos mesmos para tratar fibrose cística |
| AR108203A1 (es) | 2016-04-07 | 2018-07-25 | Proteostasis Therapeutics Inc | Compuestos, composiciones y métodos para modular cftr (regulador de la conductancia transmembrana de la fibrosis quística) |
| ES2954658T3 (es) | 2016-06-21 | 2023-11-23 | Proteostasis Therapeutics Inc | Compuestos, composiciones y procedimientos para aumentar la actividad de CFTR |
| CN110776504B (zh) * | 2019-11-29 | 2021-07-30 | 扬州工业职业技术学院 | 一种苯异噁唑乙氧基环丁胺衍生物及其制备方法与应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL372887A1 (en) | 2002-02-27 | 2005-08-08 | Pfizer Products Inc. | Acc inhibitors |
| DE102005055726A1 (de) | 2005-11-23 | 2007-08-30 | Sanofi-Aventis Deutschland Gmbh | Hydroxy-substituierte Diphenylazetidinone, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| KR20080087833A (ko) | 2005-12-21 | 2008-10-01 | 쉐링 코포레이션 | 히스타민 h3 길항제로서 유용한 페녹시피페리딘 및 이의유사체 |
| JP2009539884A (ja) * | 2006-06-12 | 2009-11-19 | メルク フロスト カナダ リミテツド | ステアロイル−コエンザイムaデルタ−9デサチュラーゼのインヒビターとしてのアゼチジン誘導体 |
| JP2012505839A (ja) | 2008-10-17 | 2012-03-08 | メルク カナダ インコーポレイテッド | ステアロイル−コエンザイムaデルタ−9デサチュラーゼの阻害剤としてのアゼチジン誘導体 |
| US20100280067A1 (en) | 2009-04-30 | 2010-11-04 | Pakala Kumara Savithru Sarma | Inhibitors of acetyl-coa carboxylase |
| MA34245B1 (fr) | 2010-04-27 | 2013-05-02 | Takeda Pharmaceutcal Company Ltd | Dérivés de composés bicycliques et leur utilisation en tant qu'inhibiteurs de l'acc. |
| KR101564806B1 (ko) * | 2010-05-13 | 2015-10-30 | 암젠 인크 | Pde10 저해제로서 유용한 질소 헤테로시클릭 화합물 |
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2012
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- 2012-12-28 EA EA201400771A patent/EA201400771A1/ru unknown
- 2012-12-28 CN CN201280068972.3A patent/CN104093705A/zh active Pending
- 2012-12-28 JP JP2014549480A patent/JP6130399B2/ja not_active Expired - Fee Related
- 2012-12-28 AU AU2012360797A patent/AU2012360797A1/en not_active Abandoned
- 2012-12-28 BR BR112014015845A patent/BR112014015845A8/pt not_active Application Discontinuation
- 2012-12-28 CA CA2861013A patent/CA2861013A1/en not_active Abandoned
- 2012-12-28 WO PCT/EP2012/077027 patent/WO2013098375A1/en not_active Ceased
- 2012-12-28 EP EP12813379.0A patent/EP2797884B1/en active Active
- 2012-12-28 KR KR1020147018007A patent/KR20140115307A/ko not_active Withdrawn
- 2012-12-28 MX MX2014007897A patent/MX2014007897A/es unknown
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2014
- 2014-06-02 IL IL232914A patent/IL232914A0/en unknown
- 2014-06-30 PH PH12014501514A patent/PH12014501514A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US8623860B2 (en) | 2014-01-07 |
| EA201400771A1 (ru) | 2014-12-30 |
| BR112014015845A8 (pt) | 2017-07-04 |
| EP2797884B1 (en) | 2016-04-13 |
| WO2013098375A1 (en) | 2013-07-04 |
| EP2797884A1 (en) | 2014-11-05 |
| JP2015506355A (ja) | 2015-03-02 |
| CA2861013A1 (en) | 2013-07-04 |
| PH12014501514A1 (en) | 2014-10-08 |
| CN104093705A (zh) | 2014-10-08 |
| AU2012360797A1 (en) | 2014-06-12 |
| US20130172316A1 (en) | 2013-07-04 |
| JP6130399B2 (ja) | 2017-05-17 |
| BR112014015845A2 (pt) | 2017-06-13 |
| IL232914A0 (en) | 2014-08-03 |
| KR20140115307A (ko) | 2014-09-30 |
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