MX2014005152A - Pharmaceutical composition for the treatment of allopathic pain, using ketorolac tromethamine and tramadol hydrochloride as an active ingredient. - Google Patents
Pharmaceutical composition for the treatment of allopathic pain, using ketorolac tromethamine and tramadol hydrochloride as an active ingredient.Info
- Publication number
- MX2014005152A MX2014005152A MX2014005152A MX2014005152A MX2014005152A MX 2014005152 A MX2014005152 A MX 2014005152A MX 2014005152 A MX2014005152 A MX 2014005152A MX 2014005152 A MX2014005152 A MX 2014005152A MX 2014005152 A MX2014005152 A MX 2014005152A
- Authority
- MX
- Mexico
- Prior art keywords
- allopathic
- pain
- treatment
- pharmaceutical composition
- tramadol hydrochloride
- Prior art date
Links
- PPKXEPBICJTCRU-XMZRARIVSA-N (R,R)-tramadol hydrochloride Chemical compound Cl.COC1=CC=CC([C@]2(O)[C@H](CCCC2)CN(C)C)=C1 PPKXEPBICJTCRU-XMZRARIVSA-N 0.000 title abstract 2
- 229960004384 ketorolac tromethamine Drugs 0.000 title abstract 2
- BWHLPLXXIDYSNW-UHFFFAOYSA-N ketorolac tromethamine Chemical compound OCC(N)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 BWHLPLXXIDYSNW-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229960003107 tramadol hydrochloride Drugs 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title 1
- 206010037660 Pyrexia Diseases 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to an injectable pharmaceutical composition combining ketorolac tromethamine/tramadol hydrochloride, for the treatment of allopathic pain (moderate to severe), used as an analgesic, anti-inflammatory, fever reducer or antipyretic, using fewer excipients that do not contribute to the desired therapeutic effect.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2014005152A MX2014005152A (en) | 2014-04-29 | 2014-04-29 | Pharmaceutical composition for the treatment of allopathic pain, using ketorolac tromethamine and tramadol hydrochloride as an active ingredient. |
| PCT/IB2015/053097 WO2015166418A2 (en) | 2014-04-29 | 2015-04-29 | Pharmaceutical composition for the treatment of allopathic pain, using ketorolac tromethamine and tramadol hydrochloride as an active ingredient |
| CL2016002655A CL2016002655A1 (en) | 2014-04-29 | 2016-10-19 | Pharmaceutical composition for the treatment of pain-related allopathies, using as active agent ketorolac tromethamine and tramadol hydrochloride |
| SV2016005308A SV2016005308A (en) | 2014-04-29 | 2016-10-28 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ALOPATHIES RELATED TO PAIN, USING AS ACTIVE AGENT TO KETOROLACO TROMETAMINE AND TRAMADOL CHLORHYDRATE |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2014005152A MX2014005152A (en) | 2014-04-29 | 2014-04-29 | Pharmaceutical composition for the treatment of allopathic pain, using ketorolac tromethamine and tramadol hydrochloride as an active ingredient. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2014005152A true MX2014005152A (en) | 2015-10-28 |
Family
ID=54359444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014005152A MX2014005152A (en) | 2014-04-29 | 2014-04-29 | Pharmaceutical composition for the treatment of allopathic pain, using ketorolac tromethamine and tramadol hydrochloride as an active ingredient. |
Country Status (4)
| Country | Link |
|---|---|
| CL (1) | CL2016002655A1 (en) |
| MX (1) | MX2014005152A (en) |
| SV (1) | SV2016005308A (en) |
| WO (1) | WO2015166418A2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019143234A1 (en) | 2018-01-22 | 2019-07-25 | AMÉZCUA AMÉZCUA, Federico | Synergistic pharmaceutical combination of the active enantiomer s-ketorolac tromethamine and tramadol chlorhydrate |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019122982A1 (en) | 2017-12-21 | 2019-06-27 | Grünenthal GmbH | Pharmaceutical combination in a bilayer tablet form comprising ketorolac tromethamine and tramadol hydrochloride, and its use in pain treatment |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA03012048A (en) * | 2003-12-19 | 2005-06-23 | Victor Guillermo Alvarez Ochoa | Pharmaceutical composition in capsules comprising a non-steroidal anti-inflammatory and an opiate analgesic for handling pain. |
| MX2010011193A (en) * | 2010-10-12 | 2012-04-18 | World Trade Imp Exp Wtie Ag | Liquid pharmaceutical composition for pain treatment and prevention. |
| WO2013163142A1 (en) * | 2012-04-25 | 2013-10-31 | Yung Shin Pharm. Ind. Co., Ltd. | Liquid pharmaceutical formulation containing ketorolac and tramadol |
-
2014
- 2014-04-29 MX MX2014005152A patent/MX2014005152A/en unknown
-
2015
- 2015-04-29 WO PCT/IB2015/053097 patent/WO2015166418A2/en not_active Ceased
-
2016
- 2016-10-19 CL CL2016002655A patent/CL2016002655A1/en unknown
- 2016-10-28 SV SV2016005308A patent/SV2016005308A/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019143234A1 (en) | 2018-01-22 | 2019-07-25 | AMÉZCUA AMÉZCUA, Federico | Synergistic pharmaceutical combination of the active enantiomer s-ketorolac tromethamine and tramadol chlorhydrate |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015166418A2 (en) | 2015-11-05 |
| CL2016002655A1 (en) | 2017-02-17 |
| WO2015166418A3 (en) | 2016-01-07 |
| SV2016005308A (en) | 2017-05-15 |
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