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MX2014002228A - Liposoma que contiene al menos un derivado de colesterol. - Google Patents

Liposoma que contiene al menos un derivado de colesterol.

Info

Publication number
MX2014002228A
MX2014002228A MX2014002228A MX2014002228A MX2014002228A MX 2014002228 A MX2014002228 A MX 2014002228A MX 2014002228 A MX2014002228 A MX 2014002228A MX 2014002228 A MX2014002228 A MX 2014002228A MX 2014002228 A MX2014002228 A MX 2014002228A
Authority
MX
Mexico
Prior art keywords
cholesterol derivative
liposome
liposomes
relates
cholesterol
Prior art date
Application number
MX2014002228A
Other languages
English (en)
Inventor
Corinne Chaimbault
Magali Michaud
Patrick Berna
Sophie Schaller
Firas Bassissi
Simon Eastman
Original Assignee
Trophos
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trophos filed Critical Trophos
Publication of MX2014002228A publication Critical patent/MX2014002228A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a una nueva forma galénica de un derivado de colesterol. Más particularmente la invención se refiere a liposomas que comprenden al menos un derivado de colesterol y a composiciones que contienen esos liposomas.
MX2014002228A 2011-08-25 2012-08-22 Liposoma que contiene al menos un derivado de colesterol. MX2014002228A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1102594A FR2979239A1 (fr) 2011-08-25 2011-08-25 Liposome comprenant au moins un derive de cholesterol
FR1102862A FR2979240A1 (fr) 2011-08-25 2011-09-21 Liposome comprenant au moins un derive de cholesterol
PCT/FR2012/051924 WO2013026989A2 (fr) 2011-08-25 2012-08-22 Liposome comprenant au moins un derive de cholesterol

Publications (1)

Publication Number Publication Date
MX2014002228A true MX2014002228A (es) 2014-05-28

Family

ID=45422200

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014002228A MX2014002228A (es) 2011-08-25 2012-08-22 Liposoma que contiene al menos un derivado de colesterol.

Country Status (9)

Country Link
US (2) US20150056269A1 (es)
EP (1) EP2747750A2 (es)
JP (2) JP6162699B2 (es)
CN (1) CN103764122A (es)
BR (1) BR112014004163A2 (es)
CA (1) CA2845691A1 (es)
FR (2) FR2979239A1 (es)
MX (1) MX2014002228A (es)
WO (1) WO2013026989A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019210204B2 (en) 2018-01-18 2024-05-16 EndoProtech, Inc. Treating microvascular dysfunction
CN114053431B (zh) * 2020-08-05 2025-11-04 四川科伦药物研究院有限公司 具有sting激动活性的化合物的脂质体组合物及其制备方法和用途

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7900458L (sv) * 1978-01-27 1979-07-28 Sandoz Ag Liposom-avgivningssystem for lekemedel
US4975282A (en) * 1985-06-26 1990-12-04 The Liposome Company, Inc. Multilamellar liposomes having improved trapping efficiencies
DE3542773A1 (de) * 1985-12-04 1987-06-11 Roehm Pharma Gmbh Hautwirksame pharmaka mit liposomen als wirkstofftraeger
FR2650181B1 (fr) * 1989-07-27 1993-12-03 Laboratoire Stallergenes Procede pour combiner un melange de substances heterogenes a des liposomes
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
DE4432378A1 (de) * 1994-09-12 1996-03-14 Bayer Ag Injizierbare liposomale Arzneizubereitungen
CA2208215A1 (en) * 1995-10-12 1997-04-17 Supergen, Inc. Liposome formulations of 5.beta. steroids
US5827533A (en) * 1997-02-06 1998-10-27 Duke University Liposomes containing active agents aggregated with lipid surfactants
WO1999013816A2 (en) * 1997-09-16 1999-03-25 Nexstar Pharmaceuticals, Inc. Liposomal camptothecin formulations
GB0111279D0 (en) * 2001-05-10 2001-06-27 Nycomed Imaging As Radiolabelled liposomes
AR031744A1 (es) * 2001-11-08 2003-10-01 Paoli Tomas De Proliposomas en polvo, un procedimiento para la elaboracion de dichas proliposomas en polvo, procedimiento para la preparacion de una composicion farmaceutica empleando proliposomas en polvo y aparato para ser empleado en el procedimiento de elaboracion de dichas proliposomas en polvo
JP4970932B2 (ja) * 2003-03-11 2012-07-11 トロフォ コレスト−４−エン−３−オンの誘導体の医薬としての使用、これらを含む医薬組成物、新規誘導体及びそれらの製造方法
FR2874923B1 (fr) * 2004-09-07 2006-10-27 Trophos Sa Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
AU2005302255A1 (en) * 2004-10-28 2006-05-11 Alza Corporation Lyophilized liposome formulations and method
EP2007355A2 (en) * 2005-12-08 2008-12-31 Wyeth a Corporation of the State of Delaware Liposomal compositions
FR2894968B1 (fr) 2005-12-20 2008-02-22 Trophos Sa Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation
FR2898272B1 (fr) * 2006-03-09 2008-07-04 Trophos Sa Utilisation de derives du 3,5-seco-4-nor-cholestrane pour l'obtention d'un medicament cytoprotecteur
FR2899108B1 (fr) 2006-03-31 2012-02-03 Trophos Utilisation de derives du cholest-4-en-3-one pour l'obtention d'un medicament cytoprotecteur
US20080181928A1 (en) * 2006-12-22 2008-07-31 Miv Therapeutics, Inc. Coatings for implantable medical devices for liposome delivery
EP2916054A2 (fr) 2007-03-28 2015-09-09 Fillon Technologies Valve de dosage
FR2914188B1 (fr) * 2007-03-28 2012-06-22 Trophos Nouvelle composition a base d'oxime de cholest-4-en-3-one
FR2919182B1 (fr) * 2007-07-25 2009-11-13 Trophos Utilisation d'au moins un derive oxime du 3,5-seco-4-nor-cholestane comme antioxydants
FR2919180B1 (fr) 2007-07-25 2009-11-27 Trophos Utilisation d'au moins un derive oxime de la cholest-4-en-3-one comme antioxydants
CA2704128A1 (fr) 2007-10-30 2009-07-30 Trophos Nouvelle composition pour traiter les effets secondaires des traitements anticancereux
FR2934596B1 (fr) 2008-07-30 2015-04-10 Trophos Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation
FR2940650B1 (fr) * 2008-12-29 2017-01-27 Trophos Nouveaux derives d'oxime du 3,5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant,et procede de preparation
CA2860266C (en) * 2009-04-27 2017-10-31 Iowa State University Research Foundation, Inc. Neuroprotective compounds and their use
CN101642431B (zh) * 2009-08-28 2011-02-02 海南永田药物研究院有限公司 奥扎格雷钠脂质体注射剂
WO2011092708A2 (en) * 2010-02-01 2011-08-04 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Liposomes comprising amphipathic drugs and method for their preparation

Also Published As

Publication number Publication date
CA2845691A1 (fr) 2013-02-28
US20150056269A1 (en) 2015-02-26
WO2013026989A2 (fr) 2013-02-28
FR2979240A1 (fr) 2013-03-01
JP2017122119A (ja) 2017-07-13
BR112014004163A2 (pt) 2017-03-14
WO2013026989A3 (fr) 2013-08-08
CN103764122A (zh) 2014-04-30
JP2014524460A (ja) 2014-09-22
JP6162699B2 (ja) 2017-07-12
US20160339041A1 (en) 2016-11-24
EP2747750A2 (fr) 2014-07-02
FR2979239A1 (fr) 2013-03-01

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