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MX2014000022A - Derivados de acidos carboxilicos con un anillo de oxazolo[5,4-d]pirimidina. - Google Patents

Derivados de acidos carboxilicos con un anillo de oxazolo[5,4-d]pirimidina.

Info

Publication number
MX2014000022A
MX2014000022A MX2014000022A MX2014000022A MX2014000022A MX 2014000022 A MX2014000022 A MX 2014000022A MX 2014000022 A MX2014000022 A MX 2014000022A MX 2014000022 A MX2014000022 A MX 2014000022A MX 2014000022 A MX2014000022 A MX 2014000022A
Authority
MX
Mexico
Prior art keywords
oxazolo
carboxylic acid
acid derivatives
pyridine ring
compounds
Prior art date
Application number
MX2014000022A
Other languages
English (en)
Other versions
MX365934B (es
Inventor
Matthias Schäfer
Dieter Kadereit
Stephanie Hachtel
Thomas Huebschle
Katrin Hiss
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MX2014000022A publication Critical patent/MX2014000022A/es
Publication of MX365934B publication Critical patent/MX365934B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a compuestos de fórmula I: (ver Fórmula) en donde A, X, Y, R1, R2, R3 tienen los significados ya indicados. Los compuestos de fórmula I son adecuados por ejemplo para cicatrización de heridas.
MX2014000022A 2011-07-07 2012-07-06 Derivados de acidos carboxilicos con un anillo de oxazolo[5,4-d]pirimidina. MX365934B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11305878 2011-07-07
EP12305526 2012-05-11
PCT/EP2012/063298 WO2013004827A1 (de) 2011-07-07 2012-07-06 Carbonsäurederivate mit einem Oxazolo[5,4-d]Pyrimidinring

Publications (2)

Publication Number Publication Date
MX2014000022A true MX2014000022A (es) 2014-02-19
MX365934B MX365934B (es) 2019-06-20

Family

ID=46458547

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014000022A MX365934B (es) 2011-07-07 2012-07-06 Derivados de acidos carboxilicos con un anillo de oxazolo[5,4-d]pirimidina.

Country Status (16)

Country Link
US (1) US9321787B2 (es)
EP (1) EP2729471B1 (es)
JP (1) JP5913585B2 (es)
KR (1) KR20140061385A (es)
CN (1) CN103781792B (es)
AU (1) AU2012280207B2 (es)
BR (1) BR112014000118A2 (es)
CA (1) CA2841226C (es)
DK (1) DK2729471T3 (es)
ES (1) ES2544620T3 (es)
IL (1) IL230258A (es)
MX (1) MX365934B (es)
MY (1) MY164134A (es)
PT (1) PT2729471E (es)
RU (1) RU2609008C2 (es)
WO (1) WO2013004827A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9321787B2 (en) 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring
CN103992279B (zh) * 2014-06-06 2016-06-01 重庆华邦胜凯制药有限公司 一种制备硫代巴比妥酸化合物的方法
JP6661885B2 (ja) * 2015-03-09 2020-03-11 セイコーエプソン株式会社 画像表示装置

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679682A (en) * 1970-04-23 1972-07-25 Fmc Corp CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES
AU6419899A (en) * 1998-10-09 2000-05-01 Regents Of The University Of Michigan, The Hydrogels and water soluble polymeric carriers for drug delivery
JP2003508127A (ja) * 1999-08-27 2003-03-04 デパートメント オブ ナショナル ディフェンス リポソームで被包された治療薬を含むヒドロゲル傷被覆用品
DE102005018389A1 (de) * 2005-04-20 2006-10-26 Sanofi-Aventis Deutschland Gmbh Azolderivate als Inhibitoren von Lipasen und Phospholipasen
CN101208340B (zh) * 2005-06-27 2010-12-22 塞诺菲-安万特股份有限公司 作为β-肾上腺素能受体激酶1抑制剂的吡唑并吡啶衍生物
EP1964840A1 (en) * 2007-02-28 2008-09-03 sanofi-aventis Imidazo[1,2-a]pyridines and their use as pharmaceuticals
WO2009155017A2 (en) * 2008-05-30 2009-12-23 Merck & Co., Inc. Novel substituted azabenzoxazoles
TW201000099A (en) 2008-06-20 2010-01-01 Amgen Inc S1P1 receptor agonists and use thereof
EP2318415B1 (en) 2008-07-15 2013-02-20 Sanofi Oxazolopyrimidines as edg-1 receptor agonists
AR079981A1 (es) 2010-01-13 2012-03-07 Sanofi Aventis Derivados de acido carboxilico que comprenden un anillo de oxoazolopirimidina 2,5,7- sustituido
TWI485153B (zh) 2010-01-13 2015-05-21 Sanofi Aventis ２，５，７－經取代唑并嘧啶衍生物
UY33178A (es) 2010-01-13 2011-08-31 Sanofi Aventis Derivados de ácido carboxílico heteroxíclicos que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido
DK2523963T3 (en) 2010-01-14 2014-12-01 Sanofi Sa 2,5-substituted oxazolopyrimidinderivater as edg-1 agonists
ES2437471T3 (es) 2010-01-14 2014-01-10 Sanofi Derivados de ácido carboxílico heterocíclicos con un anillo de oxazolopirimidina 2,5-sustituida
BR112012017437B1 (pt) * 2010-01-14 2022-03-03 Sanofi Compostos derivados de ácido carboxílicotendo um anel de oxazolopirimidina 2,5- substituído, seu processo de preparação e composição farmacêutica que os compreende
US9321787B2 (en) 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring
US8735402B2 (en) 2011-07-07 2014-05-27 Sanofi Cycloalkyloxycarboxylic acid derivatives
US8580816B2 (en) 2011-07-07 2013-11-12 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-b]pyridine ring
US8907093B2 (en) * 2011-07-07 2014-12-09 Sanofi Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring

Also Published As

Publication number Publication date
US9321787B2 (en) 2016-04-26
IL230258A (en) 2016-08-31
JP5913585B2 (ja) 2016-04-27
PT2729471E (pt) 2015-09-16
AU2012280207B2 (en) 2017-03-09
AU2012280207A1 (en) 2014-01-23
MY164134A (en) 2017-11-30
EP2729471B1 (de) 2015-05-06
ES2544620T3 (es) 2015-09-02
JP2014518248A (ja) 2014-07-28
RU2014104230A (ru) 2015-08-20
US20130023544A1 (en) 2013-01-24
CN103781792B (zh) 2016-06-29
WO2013004827A1 (de) 2013-01-10
KR20140061385A (ko) 2014-05-21
EP2729471A1 (de) 2014-05-14
MX365934B (es) 2019-06-20
HK1192240A1 (en) 2014-08-15
CA2841226C (en) 2019-11-12
CA2841226A1 (en) 2013-01-10
DK2729471T3 (en) 2015-08-10
BR112014000118A2 (pt) 2017-01-10
RU2609008C2 (ru) 2017-01-30
CN103781792A (zh) 2014-05-07

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