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MX2013014239A - Derivados de 1,3-dioxoindeno, sal farmaceuticamente aceptable de los mismos, metodos de preparacion de los mismos y composicion farmaceutica para el antivirus que contiene el mismo como un ingrediente activo. - Google Patents

Derivados de 1,3-dioxoindeno, sal farmaceuticamente aceptable de los mismos, metodos de preparacion de los mismos y composicion farmaceutica para el antivirus que contiene el mismo como un ingrediente activo.

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Publication number
MX2013014239A
MX2013014239A MX2013014239A MX2013014239A MX2013014239A MX 2013014239 A MX2013014239 A MX 2013014239A MX 2013014239 A MX2013014239 A MX 2013014239A MX 2013014239 A MX2013014239 A MX 2013014239A MX 2013014239 A MX2013014239 A MX 2013014239A
Authority
MX
Mexico
Prior art keywords
viral
pharmaceutically acceptable
active ingredient
composition containing
pharmaceutical composition
Prior art date
Application number
MX2013014239A
Other languages
English (en)
Other versions
MX355498B (es
Inventor
Johan Neyts
Young Sik Jung
Chong Kgo Lee
Hae Soon Kim
Pil Ho Kim
Soo Bong Han
Hendrik Jan Thibaut
Ihl Young Choi
Original Assignee
Univ Leuven Kath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leuven Kath filed Critical Univ Leuven Kath
Publication of MX2013014239A publication Critical patent/MX2013014239A/es
Publication of MX355498B publication Critical patent/MX355498B/es

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Abstract

Se describe derivados de 1,3-Dioxoindeno, sales farmacéuticamente aceptables de los mismos o enantiómeros, un método de preparación de los mismos, y una composición farmacéutica para la prevención o tratamiento de enfermedades virales, que comprenden los mismos como un ingrediente activo. Los derivados de 1,3-Dioxoindeno tienen excelente actividad inhibitoria contra picornavirus incluyendo virus coxsackie, enterovirus, ecovirus, poliovirus y rinovirus, así como exhiben baja citotoxicidad, de modo que pueden ser útiles como un ingrediente activo de una composición farmacéutica para la prevención y tratamiento de enfermedades virales incluyendo poliomielitis, parálisis, conjuntivitis hemorrágica aguda, meningitis viral, enfermedad de manos pies y boca, enfermedad vesicular, hepatitis A, miositis, miocarditis, pancreatitis, diabetes, mialgia epidémica, encefalitis, resfriado, herpangina, enfermedad de pies y boca, asma, enfermedad pulmonar obstructiva crónica, neumonía, sinusitis u otitis media.
MX2013014239A 2011-06-16 2012-06-18 Derivados de 1,3-dioxoindeno, sal farmaceuticamente aceptable de los mismos, metodos de preparacion de los mismos y composicion farmaceutica para el antivirus que contiene el mismo como un ingrediente activo. MX355498B (es)

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KR20110058704 2011-06-16
KR1020120065023A KR101391745B1 (ko) 2011-06-16 2012-06-18 1,3-다이옥소인덴 유도체, 이의 약학적으로 허용되는 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 항바이러스용 약학적 조성물
PCT/KR2012/004804 WO2012173447A2 (ko) 2011-06-16 2012-06-18 1,3-다이옥소인덴 유도체, 이의 약학적으로 허용되는 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 항바이러스용 약학적 조성물

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MX2013014239A true MX2013014239A (es) 2014-05-14
MX355498B MX355498B (es) 2018-04-20

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WO2014092514A1 (ko) * 2012-12-14 2014-06-19 한국화학연구원 신규한 화합물, 이의 약학적으로 허용가능한 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 바이러스성 질환의 예방 또는 치료용 약학적 조성물
CN104557559B (zh) * 2015-01-14 2016-08-17 成都中医药大学 茚满二酮手性环己烷螺环化合物及其制备方法与用途
KR102067858B1 (ko) 2016-05-24 2020-01-17 주식회사 엘지화학 화합물 및 이를 포함하는 색재 조성물 및 이를 포함하는 수지 조성물
JP7592748B2 (ja) 2020-04-20 2024-12-02 ノバルティス アーゲー 抗ウイルス１，３－ジ－オキソ－インデン化合物
CN120590351A (zh) * 2020-04-20 2025-09-05 诺华股份有限公司 抗病毒素1,3-二氧代茚化合物

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EP4360710A3 (en) 2024-08-07
EP2722322B8 (en) 2020-03-11
RU2566761C2 (ru) 2015-10-27
RU2014101179A (ru) 2015-07-27
EA025384B1 (ru) 2016-12-30
BR112013032273B1 (pt) 2020-11-17
JP6373297B2 (ja) 2018-08-15
JP2016185967A (ja) 2016-10-27
US20160272564A1 (en) 2016-09-22
EA201490025A1 (ru) 2014-05-30
ES2744982T3 (es) 2020-02-27
WO2012173447A2 (ko) 2012-12-20
BR112013032273A2 (pt) 2016-12-20
US20140121187A1 (en) 2014-05-01
JP2014523416A (ja) 2014-09-11
US9833423B2 (en) 2017-12-05
EP2722322A4 (en) 2014-12-17
AU2012270310A1 (en) 2012-12-20
KR101391745B1 (ko) 2014-05-07
EP4360710A2 (en) 2024-05-01
AU2012270310A8 (en) 2014-01-23
JP5941142B2 (ja) 2016-06-29
CN103748060B (zh) 2016-04-13
CN103748060A (zh) 2014-04-23
CA2838680C (en) 2018-01-02
EP2722322B1 (en) 2019-06-12
US9346749B2 (en) 2016-05-24
MX355498B (es) 2018-04-20
EP2722322A2 (en) 2014-04-23
AU2012270310B2 (en) 2016-01-28
EP3611158B1 (en) 2023-12-20
WO2012173447A3 (ko) 2013-04-04
PT2722322T (pt) 2019-09-27
EP3611158A1 (en) 2020-02-19
PL2722322T3 (pl) 2020-02-28
CA2838680A1 (en) 2012-12-20
SI2722322T1 (sl) 2019-11-29

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