MX2013013185A - Proteina f, una nueva adhesina de haemophilus influenzae con propiedades de unión a la laminina y vitronectina. - Google Patents
Proteina f, una nueva adhesina de haemophilus influenzae con propiedades de unión a la laminina y vitronectina.Info
- Publication number
- MX2013013185A MX2013013185A MX2013013185A MX2013013185A MX2013013185A MX 2013013185 A MX2013013185 A MX 2013013185A MX 2013013185 A MX2013013185 A MX 2013013185A MX 2013013185 A MX2013013185 A MX 2013013185A MX 2013013185 A MX2013013185 A MX 2013013185A
- Authority
- MX
- Mexico
- Prior art keywords
- protein
- haemophilus influenzae
- laminin
- binding properties
- vitronectin binding
- Prior art date
Links
- 241000606768 Haemophilus influenzae Species 0.000 title abstract 2
- 229940047650 haemophilus influenzae Drugs 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 102100035140 Vitronectin Human genes 0.000 title 1
- 108010031318 Vitronectin Proteins 0.000 title 1
- 108010037896 heparin-binding hemagglutinin Proteins 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 3
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0208—Specific bacteria not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Otolaryngology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se describe una composición de vacuna que comprende una proteína, que puede detectarse en Haemophilus influenzae, que tiene una secuencia de aminoácidos como se describe en la SEQ ID NO: 1, o un fragmento de la misma; el fragmento comprende una secuencia de aminoácidos que tiene por lo menos 15 aminoácidos contiguos de la secuencia de aminoácidos de SEQ ID NO:1, y el fragmento (si es necesario, cuando se acopla a un portador), es capaz de provocar una respuesta inmune que reconoce el polilpéptido de la SEQ ID NO: 1.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161484697P | 2011-05-11 | 2011-05-11 | |
| SE1150418 | 2011-05-11 | ||
| PCT/SE2012/050503 WO2012154121A1 (en) | 2011-05-11 | 2012-05-11 | Protein f - a novel haemophilus influenzae adhesin with laminin and vitronectin binding properties |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2013013185A true MX2013013185A (es) | 2014-06-05 |
Family
ID=47139416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013013185A MX2013013185A (es) | 2011-05-11 | 2012-05-11 | Proteina f, una nueva adhesina de haemophilus influenzae con propiedades de unión a la laminina y vitronectina. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20140286977A1 (es) |
| EP (1) | EP2707024A4 (es) |
| JP (1) | JP2014516028A (es) |
| KR (1) | KR20140066126A (es) |
| CN (1) | CN103687613A (es) |
| AU (1) | AU2012254213A1 (es) |
| BR (1) | BR112013029024A2 (es) |
| CA (1) | CA2835510A1 (es) |
| EA (1) | EA201391669A1 (es) |
| IL (1) | IL229343A0 (es) |
| MX (1) | MX2013013185A (es) |
| PH (1) | PH12013502292A1 (es) |
| SG (1) | SG194886A1 (es) |
| WO (1) | WO2012154121A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2013013185A (es) * | 2011-05-11 | 2014-06-05 | Riesbeck Healthcare Sweden Ab | Proteina f, una nueva adhesina de haemophilus influenzae con propiedades de unión a la laminina y vitronectina. |
| AU2014225330B2 (en) | 2013-03-08 | 2018-11-01 | Lauren O. Bakaletz | Transcutaneous dosage formulation |
| TW201620927A (zh) * | 2014-02-24 | 2016-06-16 | 葛蘭素史密斯克藍生物品公司 | Ｕｓｐａ２蛋白質構築體及其用途 |
| CN116940372A (zh) * | 2020-09-10 | 2023-10-24 | 罗切斯特综合医院 | 流感嗜血杆菌疫苗和使用方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA40596C2 (uk) * | 1992-05-23 | 2001-08-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини та спосіб її одержання |
| US6673910B1 (en) * | 1999-04-08 | 2004-01-06 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to M. catarrhalis for diagnostics and therapeutics |
| SE0102410D0 (sv) * | 2001-07-04 | 2001-07-04 | Arne Forsgren | Novel surface exposed immunoglobulin D-binding protein from moraxella catarrhalis |
| AU2003218162B2 (en) * | 2002-03-15 | 2009-10-29 | The Curators Of The University Of Missouri | Mutants of the P4 protein of nontypable haemophilus influenzae with reduced enzymatic activity |
| US8283114B2 (en) * | 2003-03-06 | 2012-10-09 | Nationwide Children's Hospital, Inc. | Genes of an otitis media isolate of nontypeable Haemophilus influenzae |
| GB0410866D0 (en) * | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| RU2007139915A (ru) * | 2005-03-30 | 2009-05-10 | Новартис Вэксинес Энд Дайэгностикс Инк. (Us) | Haemophilus influenzae типа в |
| JP5269594B2 (ja) * | 2005-08-10 | 2013-08-21 | アルネ・フオシユグレン・アー・ベー | モラクセラ・カタラーリスと上皮細胞、細胞外マトリックス蛋白質及び補体系の相互作用 |
| ZA200805602B (en) * | 2006-01-17 | 2009-12-30 | Arne Forsgren | A novel surface exposed haemophilus influenzae protein (protein E; pE) |
| CN101081296B (zh) * | 2006-05-29 | 2010-08-04 | 北京民海生物科技有限公司 | 一种b型流感嗜血杆菌荚膜多糖制备方法及其联合疫苗 |
| MX2013013185A (es) * | 2011-05-11 | 2014-06-05 | Riesbeck Healthcare Sweden Ab | Proteina f, una nueva adhesina de haemophilus influenzae con propiedades de unión a la laminina y vitronectina. |
| ES2649370T3 (es) * | 2011-06-06 | 2018-01-11 | Nationwide Children's Hospital, Inc. | Método de detección diagnóstica basado en la proteómica para sinusitis crónica |
| EP2917240A1 (en) * | 2012-11-07 | 2015-09-16 | Pfizer Inc. | Anti-notch3 antibodies and antibody-drug conjugates |
-
2012
- 2012-05-11 MX MX2013013185A patent/MX2013013185A/es not_active Application Discontinuation
- 2012-05-11 US US14/116,968 patent/US20140286977A1/en not_active Abandoned
- 2012-05-11 JP JP2014510278A patent/JP2014516028A/ja not_active Withdrawn
- 2012-05-11 AU AU2012254213A patent/AU2012254213A1/en not_active Abandoned
- 2012-05-11 KR KR1020137032639A patent/KR20140066126A/ko not_active Withdrawn
- 2012-05-11 PH PH1/2013/502292A patent/PH12013502292A1/en unknown
- 2012-05-11 WO PCT/SE2012/050503 patent/WO2012154121A1/en not_active Ceased
- 2012-05-11 SG SG2013083316A patent/SG194886A1/en unknown
- 2012-05-11 EP EP20120782623 patent/EP2707024A4/en not_active Withdrawn
- 2012-05-11 EA EA201391669A patent/EA201391669A1/ru unknown
- 2012-05-11 CA CA2835510A patent/CA2835510A1/en not_active Abandoned
- 2012-05-11 CN CN201280034173.4A patent/CN103687613A/zh active Pending
- 2012-05-11 BR BR112013029024A patent/BR112013029024A2/pt not_active IP Right Cessation
-
2013
- 2013-11-10 IL IL229343A patent/IL229343A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG194886A1 (en) | 2013-12-30 |
| EP2707024A1 (en) | 2014-03-19 |
| BR112013029024A2 (pt) | 2017-10-31 |
| CN103687613A (zh) | 2014-03-26 |
| IL229343A0 (en) | 2014-01-30 |
| KR20140066126A (ko) | 2014-05-30 |
| CA2835510A1 (en) | 2012-11-15 |
| PH12013502292A1 (en) | 2018-03-21 |
| EP2707024A4 (en) | 2015-03-04 |
| WO2012154121A1 (en) | 2012-11-15 |
| JP2014516028A (ja) | 2014-07-07 |
| US20140286977A1 (en) | 2014-09-25 |
| AU2012254213A1 (en) | 2013-11-28 |
| EA201391669A1 (ru) | 2014-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |