MX2013011306A - Nutritional compositions for enhancing performance and methods for making and using same. - Google Patents

Abstract

ABSTRACT OF THE DISCLOSURE A nutritional composition comprising a carbohydrate fraction comprising glucose and fructose in a ratio from about 3:1 to about 1:1, wherein: the powder nutritional composition is designed to be dissolved in water, a serving size of the nutritional composition is from about 1 to about 20 g, the carbohydrate fraction comprises at least 30% glucose and fructose, the carbohydrate fraction provides at least 50% of the energy of the nutritional composition; and the nutritional composition comprises an energy density from about 800 kJ/100 g to about 2200 kJ/100 g. The performance may be, for example, athletic, academic, or other performances requiring physical stamina and/or mental alertness. ABSTRACT OF THE DISCLOSURE A nutritional composition comprising a carbohydrate fraction comprising glucose and fructose in a ratio from about 3:1 to about 1:1, wherein: the powder nutritional composition is designed to be dissolved in water, a serving size of the nutritional composition is from about 1 to about 20 g, the carbohydrate fraction comprises at least 30% glucose and fructose, the carbohydrate fraction provides at least 50% of the energy of the nutritional composition; and the nutritional composition comprises an energy density from about 800 kJ/100 g to about 2200 kJ/100 g. The performance may be, for example, athletic, academic, or other performances requiring physical stamina and/or mental alertness. Methods for producing compositions of decellularized extracellular matrix (DM) tissue culture are described. The compositions can be used for coating supports such as tissue culture substrates, osteogenic gels, and medical devices.

Description

NUTRITIONAL COMPOSITIONS TO INCREASE PERFORMANCE AND METHODS TO MAKE AND USE THEMSELVES BACKGROUND OF THE INVENTION The present invention relates generally to health and nutrition. More specifically, the present invention relates to nutritional compositions for improving performance and methods for making and using same.

There are many types of nutritional compositions currently on the market. The nutritional compositions can be directed towards certain types of consumers, for example, children, the elderly, athletes, etc., on the basis of the specific ingredients of the nutritional composition. For example, it is well established that ingestion of carbohydrates during or before exercise improves resistance performance, as well as exercise of shorter duration. However, nutritional compositions that have an adequate amount of carbohydrates necessary to fuel the body during exercise may have unattractive features that discourage the athlete from consuming the composition. The performance compositions may be difficult to consume during exercise or they may be too dense or heavy for consumption before or during exercise, or they may have a chalky or mild flavor. As a result, individuals may be less attracted to the taste or appearance of performance compositions and, as a result, may consume smaller amounts of nutritional products containing the carbohydrates needed to properly fuel the body during performance.

One of the objectives of nutritional support, therefore, is to provide nutritional compositions that can very efficiently provide carbohydrates to individuals and an increase in the rate of oxidation of exogenous carbohydrates during exercise, while at the same time time provides an aesthetically and physically well received product.

BRIEF DESCRIPTION OF THE INVENTION The nutritional compositions of the present invention provide a refreshing and easy-to-consume composition that provides adequate amounts and types of nutrition to provide the body with the right fuel for performance. The performance can be, for example, sports, academic, or other performance that require physical resistance and / or mental alertness. In a general embodiment, a powdered nutritional composition is provided which includes a carbohydrate moiety having glucose and fructose in a ratio of about 3: 1 to about 1: 1.

In one embodiment, the powdered nutritional composition is designed to be dissolved in water.

In one embodiment, the carbohydrate fraction is at least 30% glucose and fructose. The carbohydrate fraction can also be about 50% glucose and fructose. The carbohydrate moiety may be in addition to at least about 85% glucose and fructose.

In one embodiment, the carbohydrate fraction provides at least 50% of the energy of the nutritional composition, or at least 70% of the energy of the nutritional composition.

In one embodiment, the carbohydrate moiety includes dextrose and / or maltodextrins.

In one embodiment, the nutritional composition includes less than 40 g of protein per 100 g of nutritional composition.

In one embodiment, the nutritional composition includes less than 20 g of fat per 100 g of nutritional composition.

In one embodiment, the nutritional composition includes at least one vitamin selected from the group consisting of vitamin C, vitamin E, vitamin B12, niacin, vitamin B6, folic acid, biotin, pantothenic acid, vitamin B2, vitamin B6, or combinations thereof. same. The at least one vitamin may be present in an amount that is at least 10% of the recommended daily dose.

In one embodiment, the nutritional composition includes at least one electrolyte or mineral selected from the group consisting of sodium, potassium, calcium, iron, magnesium, zinc, or combinations thereof.

In one embodiment, the nutritional composition includes at least one amino acid selected from the group consisting of L-leucine, L-valine, L-isoleucine, or combinations thereof.

In one embodiment, the nutritional composition includes an energy density of about 800 kJ / 100 g to about 2200 kJ / 100 g.

In one embodiment, a portion size of the nutritional composition is from about 1 to about 20 g, or from about 1 to about 15 g, or from about 1 g to about 6 g.

In one embodiment, the nutritional composition includes at least one compound selected from the group consisting of aroma compounds, fiber, caffeine, guarana, acidifying agents, binding agents, gel-forming material, fruits, antioxidants, coloring agents, or combinations thereof. the same.

In another embodiment, a liquid nutritional composition comprising a carbohydrate moiety comprising glucose and fructose in a ratio of about 3: 1 to about 1: 1 is provided.

In one embodiment, a portion size of the liquid nutritional composition is from about 100 mL to about 600 mL. In one embodiment, a portion size of the liquid nutritional composition is about 500 mL In yet another embodiment, a packaged food product is provided that includes an outer package that is constructed and arranged in such a way as to house a plurality of inner packages. Each inner package includes a powdered nutritional composition having a carbohydrate moiety that includes glucose and fructose in a ratio of about 3: 1 to about 1: 1.

In one embodiment, the outer package is made of a material selected from the group consisting of cardboard, plastic, metal or combinations thereof. In one embodiment, the outer package is a cardboard box.

In one embodiment, the plurality of inner packages comprises from about 5 to about 20 inner packages.

In one embodiment, each of the plurality of inner packages includes a portion size of the nutritional composition. The serving size of the nutritional composition can be from about 0.5 g to about 10 g, or from about 1 g to about 6 g, or about 3 g.

In yet another embodiment, a packaged food product is provided that includes an outer package that is constructed and arranged in such a manner as to house a powdered nutritional composition. The powdered nutritional composition includes a carbohydrate moiety having glucose and fructose in a ratio of about 3: 1 to about 1: 1.

In one embodiment, the outer package includes a food grade coating on an interior surface.

In one embodiment, the outer package also houses a spoon that is constructed to dispense a portion of the nutrition composition from the outer package.

In one embodiment, the outer package is refillable.

In yet another embodiment, a method for preparing a liquid nutritional composition is provided. The method includes emptying a powdered nutritional composition from a container sized for a single portion into a container and combining the powdered nutritional composition into the container with a liquid to form a liquid nutritional composition. The powdered nutritional composition includes a carbohydrate moiety having glucose and fructose in a ratio of about 3: 1 to about 1: 1.

In another embodiment, a method for preparing a liquid nutritional composition is provided. The method includes dispensing powdered nutrition composition from a first container in a second container and combining the powdered nutritional composition in the second container with a liquid to form a liquid nutritional composition. The first container is constructed and arranged in such a way as to contain several portions of the powdered nutritional composition. The powdered nutritional composition includes a carbohydrate moiety having glucose and fructose in a ratio of about 3: 1 to about 1: 1.

In yet another embodiment, a method is provided to improve performance in an individual who requires it. The method includes combining a powdered nutritional composition having a carbohydrate moiety having glucose and fructose in a ratio of about 3: 1 to about 1: 1 with a liquid to form a liquid nutritional composition, and administering the nutritional composition. liquid to the individual. In a modality, performance is selected from the group that it consists of athletic, academic, resistance, or combinations thereof.

In another embodiment, a method is provided for providing sustained energy to the muscles in an individual who requires it. The method includes combining a powdered nutritional composition having a carbohydrate moiety having glucose and fructose in a ratio of about 3: 1 to about 1: 1 with a liquid to form a liquid nutritional composition, and administering the nutritional composition liquid to the individual.

In yet another embodiment, a method is provided for providing an adequate carbohydrate load to an athlete who requires it. The method includes combining a powdered nutritional composition having a carbohydrate moiety having glucose and fructose in a ratio of about 3: 1 to about 1: 1 with a liquid to form a liquid nutritional composition, and administering the nutritional composition liquid to the individual.

An advantage of the present invention is to provide improved nutritional compositions.

Another advantage of the present invention is to provide nutritional compositions that are attractive to consumers.

Another advantage of the present invention is to provide nutritional compositions that provide a consumer with adequate carbohydrates for exercise.

Yet another advantage of the present invention is to provide nutritional compositions that are pleasant to prepare for the consumer.

Yet another advantage of the present invention is to provide nutritional compositions that help improve the recovery of physical activity.

Another advantage of the present invention is to provide compositions nutritional products that provide adequate nutrition for physical activity.

Another additional advantage of the present invention is to provide improved methods for the manufacture of nutritional compositions.

Yet another advantage of the present invention is to provide methods for providing adequate nutrition for physical activity to an individual who requires it.

Another advantage of the present invention is to provide methods for providing nutritional compositions to improve the recovery of physical activity to an individual who requires it.

Yet another advantage of the present invention is to provide methods for improving athletic performance in an individual who requires it.

Additional features and advantages are described in this document, and will be apparent from the following detailed description and figures.

Brief description of the figures Figure 1 shows a packaged food product according to an embodiment of the present invention.

Figures 2A-2C demonstrate a method for the manufacture of a food product according to an embodiment of the present invention.

Figures 3A-3E show different embodiments for food packages according to one embodiment of the present invention.

Figure 4 shows a food product packaged according to an embodiment of the present invention.

Detailed description of the invention In the present specification, "approximately" is understood to refer to numbers in a range of numerals. On the other hand, it should be understood that all numerical ranges in this document include all integers, complete or fractions, within the range.

As used herein, the term "amino acid" is understood to include one or more amino acids. The amino acid can be, for example, alanine, arginine, asparagine, aspartate, citrulline, cysteine, glutamate, glutamine, glycine, histidine, hydroxyproline, hydroxy-serine, hydroxytyrosine, hydroxylysine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, taurine, threonine, tryptophan, tyrosine, valine, or combinations thereof.

As used herein, the term "antioxidant" is understood to include any one or more of various substances such as beta-carotene (a precursor of vitamin A), vitamin C, vitamin E, and selenium) that inhibit oxidation or the reactions promoted by reactive oxygen species ("ROS") and other radical and non-radical species. In addition, antioxidants are molecules capable of slowing or preventing the oxidation of other molecules. Non-limiting examples of antioxidants include astaxanthin, carotenoids, coenzyme Q10 ("CoQ10"), flavonoids, glutathione, Goji (blackberry), hesperidin, lacto-mora of vision, lignans, lutein, lycopene, polyphenols, selenium, vitamin A, vitamin C, vitamin E, zeaxanthin, or combinations thereof.

While the terms "individual" and "patient" are often used in this document to refer to a human being, the invention is not so limited. Accordingly, the terms "individual" and "patient" refer to any animal, mammal or human that has or is at risk of a medical condition that can benefit from the treatment.

As used herein, sources of co-3 fatty acids include, for example, fish oil, krill, vegetable sources of? -3, linseed, walnut, and algae. Examples of fatty acids? -3 include, for example, α-linolenic acid ("ALA"), docosahexaenoic acid ("DHA"), eicosapentaenoic acid ("EPA"), or combinations thereof.

As used herein, the term "minerals" is understood to include boron, calcium, chromium, copper, iodine, iron, magnesium, manganese, molybdenum, nickel, phosphorus, potassium, selenium, silicon, tin, vanadium, zinc, or combinations thereof.

"Nutritional products" or "nutritional compositions", as used herein, is meant to include any number of optional additional ingredients, including conventional food additives (synthetic or natural), for example one or more acidulants, additional thickeners, regulators of pH or pH adjusting agents, chelating agents, colorants, emulsifiers, excipients, flavoring agents, minerals, osmotic agents, a pharmaceutically acceptable carrier, preservatives, stabilizers, sugar, sweeteners, texturizers, and / or vitamins. The optional ingredients can be added in any suitable amount. Nutritional products or compositions can be a source of complete nutrition or they can be an incomplete source of nutrition.

As used herein, the term "patient" is understood to include an animal, especially a mammal, and more especially a human being that is receiving or intended to receive treatment, as defined herein.

As used in this description and the appended claims, the singular forms "a," "an," and "the" include plural referents unless the context clearly dictates otherwise. Thus, for example, reference to "a polypeptide" includes a mixture of two or more polypeptides, and the like.

The terms "protein", "peptide", "oligopeptides" or "polypeptide", as used herein, are understood to refer to any composition that includes, a single amino acid (monomers), two or more amino acids joined by a peptide bond (dipeptide, tripeptide, or polypeptide), collagen, precursor, homologue, analog, mimetic, salt, prodrug, metabolite, or fragment thereof or combinations thereof. For the sake of clarity, the use of any of the foregoing terms is interchangeable unless otherwise specified. It will be appreciated that polypeptides (or peptides or proteins or oligopeptides) often contain amino acids other than the 20 amino acids commonly referred to as the 20 naturally occurring amino acids., and that many amino acids, including terminal amino acids, can be modified in a given polypeptide, either by natural processes such as glycosylation and other post-translational modifications, or by chemical modification techniques that are well known in the art. Among known modifications that may be present in the polypeptides of the present invention include, but are not limited to, acetylation, acylation, ADP ribosylation, amidation, covalent attachment of a flavonoid or a heme moiety, covalent attachment of a polynucleotide or derivative of polynucleotide, covalent attachment of a lipid or lipid derivative, covalent binding of phosphatidylinositol, crosslinking, delation, formation of disulfide bonds, demethylation, formation of covalent crosslinks, formation of cystine, formation of pyroglutamate, formylation, gamma-carboxylation, glycosylation, glycosylation, glycosylphosphatidyl inositol ("GPI") membrane anchoring formation, hydroxylation, iodination, methylation, myristoylation, oxidation, proteolytic processing, phosphorylation, prenylation, racemization, selenoylation, sulfation, RNA-mediated addition of amino acid transfer to polypeptides such as arginilac ion, and ubiquitination. The term "protein" also includes "artificial proteins" which refers to linear or non-linear polypeptides, which consist of alternating repeats of a peptide.

Non-limiting examples of proteins include proteins of dairy origin, proteins of vegetable origin, proteins of animal origin and artificial proteins. Dairy origin proteins can be selected from the group consisting of casein, caseinates, casein hydrolyzate, whey, whey hydrolysates, whey concentrates, whey isolates, milk protein concentrate, milk protein isolate, or combinations thereof. Proteins of plant origin include, for example, soy protein (e.g., all forms including concentrate and isolate), pea protein (e.g., all forms including concentrate and isolate), cañola protein (e.g., all the forms including concentrated and isolated), other vegetable proteins that are commercially split wheat and wheat proteins, corn and its fractions including zein, rice, oats, potatoes, peanuts, and any of the proteins derived from grains, buckwheat, lentils, legumes, unicellular proteins, or combinations thereof. The proteins of animal origin may be selected from the group consisting of beef, poultry, fish, lamb, shellfish, or combinations thereof.

All dosage ranges contained within this application are intended to include all numbers, integers or fractions, contained within said range.

As used herein, the terms "treatment", "treating" and "alleviating" include both prophylactic and preventive treatment (which prevent and / or delay the development of a specific pathological condition or disorder) and curative, therapeutic or disease modifier, including therapeutic measures that cure, slow down, reduce the symptoms of, and / or stop the progression of a diagnosed pathological condition or disorder; and the treatment of patients at risk of contracting a disease or suspected of having contracted a disease, as well as patients who are ill or have been diagnosed as suffering from a disease or medical condition. The term does not necessarily imply that the subject is treated until full recovery. The terms "treatment" and "treating" also refer to the maintenance and / or promotion of health in an individual who does not suffer from a disease, but who could be susceptible to the appearance of an unhealthy state, such as nitrogen imbalance or loss of muscle mass. The terms "treatment", "treating" and "alleviating" are also intended to include potentiation or otherwise the improvement of one or more primary prophylactic or therapeutic measures. The terms "treatment", "treating" and "alleviating" are also intended to include dietary treatment of a disease or condition or dietary treatment for the prophylaxis or prevention of a disease or condition.

As used herein, the term "vitamin" is understood to include any of the various organic substances soluble in fat or water soluble (non-limiting examples include vitamin A, vitamin B1 (thiamine), vitamin B2 (riboflavin), vitamin B3 (niacin or niacinamide), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine, pyridoxal or pyridoxamine, or pyridoxine hydrochloride), vitamin B7 (biotin), vitamin B9 (folic acid) and vitamin B12 (different cobalamins, commonly cyanocobalamin in vitamin supplements), vitamin C, vitamin D, vitamin E, vitamins K, K1 and K2 (ie, MK-4, MK-7), folic acid and biotin) essential in minute quantities for normal body growth and activity and naturally obtained from vegetable and animal or synthetically prepared foods, provitamins, derivatives, analogues.

The present nutritional compositions are directed to compositions Nutritionals that are designed to provide adequate nutrition for performance and to be reconstituted in a liquid by the consumer before consumption. Energy and / or performance bars are known in the art and are commonly consumed by people who require increased carbohydrate loading for improved or sustained sports performance, or increased mental alertness. These types of known performance rods, however, may suffer from certain limitations or difficulties in the eyes of consumers.

For example, known performance rods can be heavy or dense or have a chalk or soft flavor. Although performance bars provide people with adequate nutrition for prolonged performance or endurance, the individual can not enjoy consuming these types of performance bars. Instead, the consumer may prefer a different source of adequate nutrition that is refreshing and easier to consume. Thus, the nutritional compositions of the present invention provide formulations that can very efficiently provide carbohydrates to athletes and a higher oxidation rate of exogenous carbohydrates before or during exercise, while at the same time being pleasant to prepare and consume.

Although the nutritional compositions of the present invention are described as useful for consumption by athletes, it is clear, however, that the nutritional compositions of the present invention can be used by anyone in need of carbohydrate delivery. For example, the nutritional compositions of the present invention can be very well used as a transportable food for people who do not want to carry very heavy provisions, for example during long trips. The nutritional compositions of the present invention can also be used by people to provide the body with carbohydrates, for example before or during an examination at school or at the university.

In one embodiment, the nutritional compositions of the present invention are directed to powder compositions having substantially the same nutritional content as the known performance bars. One of these performance bars is the PowerBar® Performance® Bar manufactured by Nestlé Nutrition. The powder compositions are designed to be reconstituted in water before consumption by the consumer. Although nutritional compositions are disclosed herein in the form of powder compositions requiring reconstitution, one skilled in the art will appreciate immediately that the nutritional compositions can also be ready-to-drink compositions that include the powder compositions described herein. reconstituted in water. These ready-to-drink compositions can be sold in different serving sizes depending on the carbohydrate loading requirements. For example, ready-to-drink compositions can be sold in portion sizes from about 18 milliliters to about 946 milliliters. In one embodiment, ready-to-drink compositions are sold in portion sizes from about 236 milliliters to about 472 milliliters. In one embodiment, ready-to-drink compositions are sold in serving sizes of approximately 355 milliliters.

Since performance rods typically include beneficial ingredients such as, for example, energy-rich cereals and fresh fruit, the nutritional compositions of the present invention are capable of providing the same beneficial ingredients, but in powder form. In this way, the consumer is able to obtain all the benefits of the solid yield bar, but in a convenient and tasty beverage after the powder is reconstituted in water or other suitable liquid such as, for example, fruit juice.

The powdered nutritional compositions of the present invention can be provided in various ways useful to the consumer. In a first embodiment, the powdered nutritional composition is packaged in individual envelopes that are designed for individual use. For example, and as shown in Figure 1, a retail package 10 for containing powdered nutritional compositions includes an outer package 12 that is configured to contain several individual envelopes 14, or packages, containing the powdered nutritional composition (not shown). The outer package 12 can be of any size and shape known in the art, as long as the outer package 12 is capable of containing several individual envelopes 14. The outer package 12 can be made of a material such as cardboard, plastic, metal, and similar. The outer package 12 may also include marks and / or indicia of product on any outer wall. The signs can be printed on it or attached to it with a decal, sticker, etc. In this way, the outer package 12 can be designed to stand upright to be displayed on a retail shelf.

The individual envelopes 14 can also be manufactured from a material such as cardboard, plastic, and the like, and may also contain marks and / or product information or indicia therein. The individual envelopes 14 must be constructed and arranged in such a way that they are contained in the outer container 12 and easily opened by a consumer to empty the contents therein. For example, to use individual envelopes 14, the user can open an individual envelope 14 by tearing, piercing or removing a portion of the wrapper, as shown in FIG. 2A, and emptying the powdered nutritional composition 16 from the individual envelope. 14 in a container 18, as shown in Figure 2B. The container 18 may already contain a reconstitution liquid, such as, for example, water or fruit juice, or it may be filled with a reconstitution liquid after the powdered nutritional composition 16 is emptied therein. As shown in Figure 2C, to prepare the nutritional composition for consumption, the consumer can shake the container 18 to completely dissolve the powdered nutritional composition 16 in the reconstitution liquid. After the dissolution of the powdered nutritional composition 16, the nutritional beverage is ready for consumption.

The sachets 14 may have any shape and size known in the art as long as the sachets 14 are configured to contain the powdered nutritional composition 16 and are easily opened by a consumer to prepare a liquid nutritional composition. Examples of different envelope configurations 14 are shown in Figures 3A-3E. Figure 3A shows a substantially rectangular envelope 14 with a pre-formed teardrop shaped notch 5. Figure 3B illustrates a wedge or arrow shaped envelope 14 with a preformed perforation 22. Figure 3C illustrates a substantially rectangular envelope 14 with a triangular top and a preformed perforation 24. Figure 3D illustrates a substantially rectangular envelope 14 with a inclined upper part and a preformed perforation 26. Figure 3E illustrates a substantially rectangular envelope 14 with an inclined upper part, which also has a rectangular portion and a preformed perforation 28. The sizes of a single portion of the nutritional compositions contained in the envelopes individual 14 can vary from about 1 g to about 20 g. In one embodiment, the portion sizes of the nutritional compositions contained in the sachets of 14 vary from about 1 g to about 15 g, or from about 1 g to about 6 g, or about 3 g.

In another embodiment, and as shown in Figure 4, a retail package 30 for containing the powdered nutritional composition includes an outer package 32 containing the powdered nutritional composition (not shown). The outer package 32 can be any size or shape known in the art as long as the outer package 32 is capable of containing multiple portions of the powdered nutritional composition. The outer package 32 can be made of a material such as cardboard, plastic, metal, and the like. In one embodiment, the outer package 32 is constructed and arranged to directly contact the powdered nutritional composition contained therein. Thus, in one embodiment, the outer package 32 may include a food grade coating on an interior surface to avoid potential contamination of the nutritional composition or moisture transfer to or from the nutritional composition. The retail package 30 may also include a spoon 34 that is designed to collect a measured amount of the powdered nutritional composition to facilitate measurement of the nutritional composition by the consumer.

By offering individual packages 14 and / or the retail package 30 with the spoon 34, the consumer is able to prepare a liquid nutritional composition (eg, beverage) that exactly matches the carbohydrate needs of consumers. For example, for a normal workout, the consumer may use an individual envelope 14 dissolved in a single portion of reconstitution liquid. For normal training, the consumer may also use one scoop of the powdered nutritional composition of the retail container 30 with a bucket 34 dissolved in a single portion of reconstitution liquid. For more rigorous training, however, the consumer may choose to use two or more individual sachets 14 dissolved in a single portion of reconstitution liquid, or two or more tablespoons of the powdered nutritional composition of the retail container 30 with a ladle of 34 dissolved in a single portion of reconstitution liquid. Thus, the nutritional compositions of the present invention can be adapted to the individual needs of each athlete.

As mentioned above, since performance rods usually include beneficial ingredients, such as, for example, energy-rich cereals and fresh fruit, the powdered nutritional compositions of the present invention are capable of providing the same beneficial ingredients, but in the form of dust. In this way, the consumer is able to obtain all the benefits of the solid performance bar, but in a convenient and tasty beverage after the powder is reconstituted in water.

The applicant believes that a consumption of up to 90 grams of carbohydrates ("CHO") per hour in the form of a liquid nutritional composition, as well as 30 to 60 g CHO / h as recommended by the American College of Sports Medicine , it is well tolerable if it is ingested as a mixture of carbohydrates comprising glucose and fructose in a ratio in the range of 3: 1 to 1: 1, or more specifically 2: 1. In addition, the gastric tolerance of a composition Liquid nutritional provides a mixture of glucose and fructose at relatively high rates during a real-life situation of either running or biking outdoors.

The applicant further believes that the ingestion of 90 grams / h of the above carbohydrate mixture will allow keeping the distention of the gastrointestinal tract of the athletes to the minimum, and at approximately a 15% rate of the subjects. On the other hand, it is believed that the minimum Gl distension will not increase compared to an intake of 60 grams of a carbohydrate mixture comprising glucose and fructose in a ratio in the range of 3: 1 to 1: 1, preferably 2: 1 per hour.

Accordingly, one embodiment of the present invention is a nutritional composition comprising a carbohydrate moiety comprising glucose and fructose in a ratio in the range of 3: 1 to 1: 1. The nutritional compositions of the present invention are food products, either (i) in powder form or (i) in liquid form as the powdered nutritional compositions reconstituted in liquid form, comprising at least one source of carbohydrates, and preferably a multiple source of carbohydrates such as the combination of glucose and fructose, or maltodextrin and fructose.

The nutritional compositions may contain a grain or grains, nuts, possibly dried fruits, fruit pulp, sweeteners and other ingredients. These ingredients can be mixed with a binder such as a sugar syrup or shortening and tablets, or powdered, and dried to form a powder.

The multiple carbohydrate source may contain fructose and glucose in a digestible form. Glucose and / or fructose can be provided in the form of fructogenic and / or glycogenic carbohydrates. Fructogenic carbohydrates are carbohydrates that release at least one molecule of fructose after release by theoretical total hydrolysis. Glycogenic carbohydrates are carbohydrates that release at least one glucose molecule after release by theoretical total hydrolysis. Accordingly, a carbohydrate can be both glycogenic and fructogenic (eg, sucrose). For example, in yield bars, glycogenic sources can also be extruded pieces of cereals, cereal flakes, flours and starches.

Therefore, carbohydrates can comprise or consist of monosaccharides, such as glucose or fructose as basic carbohydrate units. The monosaccharides may represent a part of the disaccharides, such as sucrose, lactose, maltose or cellobiose. Monosaccharides such as glucose or Fructose can also represent a part of oligosaccharides or polysaccharides. Preferred sources of carbohydrates for the present invention are maltodextrins and / or dextrose. The carbohydrate source can also comprise non-digestible carbohydrates, in particular fibers.

The carbohydrate moiety of the nutritional compositions may comprise at least 30% glucose and fructose, preferably at least 50% glucose and fructose, more preferably at least 85% glucose and fructose. In one embodiment of the present invention the carbohydrate moiety of the nutritional compositions provides at least 50%, preferably at least 70%, of the energy of the nutritional composition.

The nutritional compositions of the present invention include a carbohydrate moiety and, optionally, a protein fraction and / or a fat fraction.

The presence of proteins and / or fats in the nutritional compositions of the present invention has the advantage that in this way it is possible to provide the athlete with more complete nutrition during execution. On the other hand, the presence of proteins allows the production of a nutritional composition with a modified flavor.

As a protein source, any suitable dietary protein can be used, for example, animal proteins (such as milk proteins, meat proteins and egg proteins), vegetable proteins (such as soy protein, wheat protein, rice protein). , and pea protein); mixtures of free amino acids, or combinations thereof. In one embodiment, milk proteins such as casein and whey, and soy proteins are included in the nutritional compositions.

The proteins may be intact or hydrolyzed or a mixture of intact and hydrolyzed proteins. It may be desirable to provide partially hydrolyzed proteins (degree of hydrolysis between 2 and 20%), for example for athletes who are considered to be at risk of developing allergy to cow's milk. In addition, generally at least partially hydrolyzed proteins are easier and faster to metabolize by the body. This is especially true for amino acids. Accordingly, it is further preferred if the nutritional compositions of the present invention contain individual amino acids. In one embodiment, however, essential amino acids are included in the nutritional compositions. In one embodiment, the nutritional compositions of the present invention contain amino acids such as L-leucine, L-valine and / or L-isoleucine.

If the composition includes a source of fat, the source of fat has the advantage that, for example, an improved mouthfeel can be achieved. Any source of fat is adequate. For example, fats of animal or vegetable origin can be used. To increase the nutritional value,? -3-unsaturated and? -3-unsaturated fatty acids can be constituted by the fat source. The source of fat may also contain long chain fatty acids and / or medium chain fatty acids. For example, milk fat, canola oil, almond butter, peanut butter, corn oil and / or high oleic acid sunflower oil can be used.

Preferably, the nutritional compositions contain less than 40 g of protein per 100 g of nutritional composition and / or less than 20 g of fat per 100 g of nutritional composition.

The nutritional compositions may also contain minerals and micronutrients such as trace elements and vitamins in accordance with the recommendations of government agencies, such as the Recommended Daily Quantities in the United States ("USRDA").

The nutritional compositions may contain vitamins, such as vitamin C, vitamin E, vitamin B12, niacin, vitamin B6, folic acid, biotin, pantothenic acid, vitamin B2 and / or vitamin B6, preferably in amounts corresponding to at least 10% of the recommended daily dose. The presence of vitamins can contribute to the efficacy of the nutritional composition and can further protect the athlete. For example, the presence of vitamin C will help protect against catching a common cold. The nutritional compositions may also include electrolytes and / or minerals, such as sodium, potassium, calcium, iron, magnesium or zinc.

These nutritional compounds can be useful to replenish the body with compounds that the person is constantly losing due to the generation of sweat during exercise. They can also help prevent the generation of sore muscles after exercise.

The nutritional compositions of the present invention may further contain one or more compounds selected from the group consisting of flavor compounds, fiber, caffeine, guarana, acidifying agents, binding agents, gel forming materials, water, fruit juice, fruits, antioxidants and coloring agents.

These agents can improve the nutritional compositions of the present invention with respect to many properties, such as taste, consistency, color, and storage stability, digestibility, and many more that are known to those skilled in the art. .

The energy density of the nutritional compositions is not critical to its effectiveness. However, a high energy density has the advantage that less food is needed to replenish carbohydrates as fuel for the body. Accordingly, high energy densities are preferred for the nutritional compositions of the present invention.

In one embodiment of the present invention, the nutritional compositions have an energy density of about 800 to about 2200 kJ / 100 g, or more specifically about 1000 to about 2000 kJ / 100 g. In one embodiment, the nutritional compositions have an energy density of about 1200 to about 1800 kJ / 100 g.

To be easily consumable, for example, during a competition or between competitions, the portion size of the nutritional compositions reconstituted in water is preferably relatively small. Preferably, the nutritional compositions, when present as a powdered nutritional composition reconstituted in liquid, have a portion size of about 1 18 milliliters to about 355 milliliters. In one embodiment, the nutritional compositions, when present as a powdered nutritional composition reconstituted in liquid, have a portion size of about 236 milliliters. For larger serving sizes, the nutritional compositions can be reconstituted in a liquid of about 355 to about 946 milliliters. In one embodiment, the nutritional compositions can be reconstituted in approximately 473 milliliters of liquid.

A typical nutritional composition of the present invention may comprise the following percentages of daily values ("DV") based on a diet of 2000 calories: between 4 and 6% of total fat, including between 1 and 3% of saturated fats, among 5 and 9% of sodium, between 0.5 and 1.5% of potassium, between 12 and 16% of carbohydrates, including between 5 and 10% of glucose and fructose, and between 10 and 14% of proteins.

In addition, it can comprise between 80 and 120% of the daily value of vitamin C, between 20 and 30% of the daily value of calcium, between 25 and 35% of the daily value of iron, between 80 and 120% of the daily value of vitamin E, between 80 and 120% of the daily value of thiamine, 4 between 80 and 120% of the daily value of riboflavin, between 80 and 120% of the daily value of niacin, between 80 and 120% of the daily value of vitamin B6, between 80 and 120% of the daily value of folate, between 80 and 120% of the daily value of vitamin B12, between 80 and 120% of the daily value of biotin, between 80 and 120% of the daily value of pantothenic acid, between 20 and 30% of the daily value of phosphorus, between 20 and 30% of the daily value of magnesium, between 25 and 35% of the daily value of zinc, between 25 and 35% of the daily value of copper, and between 15 and 25% of the daily value of chromium.

The nutritional composition of the present invention can be used, for example, as a food product, as a food additive or as a nutraceutical.

In one embodiment of the present invention, the nutritional compositions of the present invention are used for the preparation of a food product or as a food product to provide a higher yield, in particular, endurance performance.

The formulation of the nutritional compositions of the present invention can also be used to provide an increase in carbohydrate delivery without any increase in gastrointestinal disorders and / or to treat or prevent problems with the gastrointestinal tract.

The combination of glucose and fructose in the nutritional compositions of the present invention allows the high carbohydrate content of the nutritional compositions to be well tolerated by the body, hence the problems of the gastrointestinal tract that one would normally expect after a high Level of carbohydrate intake during exercise are at least partially avoided. In addition, the gastrointestinal tolerance of the carbohydrates, in particular the glucose / fructose mixture of the present invention, will be increased.

Problems with the gastrointestinal tract such as those mentioned 5 previously they are not particularly limited, but are preferably selected from the group consisting of upper abdominal problems such as reflux, heartburn, bloating, upper abdominal cramps, vomiting, nausea, lower abdominal problems, such as intestinal cramps, flatulence, urge to defecate , left abdominal pain, right abdominal pain, loose stools, diarrhea, or systemic problems such as dizziness, headache, muscle cramps or urgency to urinate.

For exercise in general, but particularly for competitive exercise, it is essential that the body have blood sugar available for the muscles to burn at all times. In particular, at the end of a race this must be avoided, or the athlete will run out of energy. The object of the present invention is very suitable for preventing this. According to one embodiment of the present invention, the nutritional compositions of the present invention can be used to allow improved blood sugar maintenance in the later stages of exercise.

The present nutritional compositions can not only ensure a long-term maintenance of blood sugar, but can also be used to provide an increase in the oxidation of exogenous carbohydrates. It was found that the increased oxidation of exogenous carbohydrates was in particular increased if a person's carbohydrate absorption is greater than 1 g / min, preferably greater than 1.1 g / min, even more preferably greater than 1. 2 g / min.

Consequently, surprisingly, optimal oxidation of exogenous carbohydrates is achieved at an intake of carbohydrates above the theoretical threshold once thought for the oxidation of carbohydrates. See, Jeukendrup AE and Jentjens R., Sports Med. 29: 407-424 (2000). In this way, the Power supply of carbohydrates during physical exercise can be maximized.

In addition, the present nutritional compositions can be used to provide a faster energy supply, in particular, to the working muscles, and / or to provide more constant energy to the muscles. Both effects contribute to an athlete's optimal performance.

The present nutritional compositions can also be used to treat or prevent symptoms of fatigue and / or to improve the pedaling cadence, for example, measured in revolutions per minute and / or to decrease the perceived effort index ("RPE").

The Applicant has found that the uses enumerated above can be carried out successfully with any amount of carbohydrates comprising glucose and fructose in a ratio of 3: T to 1: 1 to be ingested. However, the Applicant believes that better results can be obtained, when the nutritional compositions are used in an amount corresponding to an intake of at least 30 g CHO / h, preferably at least 50 g CHO / h, more preferably at least 65 g CHO / h, and most preferably between 80 g CHO / h and 1 10 g CHO / h.

The greater the amount of carbohydrates ingested per hour, the more the oxidation of exogenous carbohydrates can be increased. The Applicant believes that oxidation of exogenous carbohydrates will be reached when the nutritional compositions are consumed in such a way that 100 g - 150 g of carbohydrates are consumed per hour, preferably 1 0 g - 30 g of hydrates of carbon per hour and more preferred of 1 15 g - 125 g of carbohydrates per hour.

The nutritional compositions of the present invention provide a convenient, portable and easy-to-consume form to provide the nutritional benefits of cereals and fruits, in the same manner as solid yield bars. The nutritional compositions combine adequate nutrition and hydration, which are two key elements for high performance training. In addition, the nutritional compositions are adaptable to provide the exact nutrition and / or carbohydrate loading required by each specific consumer.

By way of example and not limitation, the following examples are illustrative of the various embodiments of the present invention. The following formulations are provided only for exemplification, and can be modified by the skilled person to the extent necessary, depending on the special characteristics that are desired.

Examples Example 1 Table 1 illustrates a comparison between a PowerBar® Performance® Bar manufactured by Nestlé Nutrition and a powdered nutritional composition of the present invention. As can be seen in Table 1, the powdered nutritional composition of the present invention is comparable with PowerBar® Performance® Bar.

Table 1 Example 2 - Female Cyclist In a first example of performance, the consumer is a female cyclist. The consumer weighs around 50 kg and pedals at a speed of around 9 km per hour. For this specific exercise profile, it is estimated that the cyclist's energy expenditure is approximately 3.5 kcal per minute (210 kcal per hour). Based on the estimated energy costs and the weight of the cyclist, it is proposed that the cyclist should consume about 50 g of powdered nutritional compositions of the present invention dissolved in approximately 100 ml_ of water.

Example 3 - Male Runner / Trotter In a second example of performance, the consumer is a male runner / trotter. The consumer weighs around 60 kg. For this specific profile of exercise, it is estimated that the energy expenditure of the male runner / trotter is approximately 7 kcal per minute (630 kcal for 90 minutes). Based on the estimated energy and weight costs of the runner / trotter, it is proposed that the male runner / trotter should consume about 150 g of a powdered nutritional composition of the present invention dissolved in approximately 300 ml_ of water.

Example 4 - Male Cyclist In a third example of performance, the consumer is a male cyclist. The consumer weighs about 80 kg and pedals at a speed that is common for a racing cyclist. For this specific profile of exercise, it is estimated that the energy expenditure of the male cyclist is approximately 14 kcal per minute (840 kcal per hour). Based on the estimated energy costs and the weight of the cyclist, it is proposed that the male cyclist should consume about 220 g of powdered nutritional compositions of the present invention dissolved in approximately 300 mL of water.

It should be understood that various changes and modifications to the currently preferred embodiments described herein will be apparent to those skilled in the art. Such changes and modifications can be made without departing from the spirit and scope of the present matter and without diminishing its desired advantages. It is therefore intended that such changes and modifications be covered by the appended claims.

Claims (23)

1. CLAIMS 1 . A nutritional composition characterized in that it comprises a carbohydrate moiety comprising glucose and fructose in a ratio of 3: 1 to 1: 1, wherein: The powdered nutritional composition is designed to be dissolved in water, a portion size of the nutritional composition is from 1 to 20 g, the carbohydrate fraction comprises at least 30% glucose and fructose, the carbohydrate fraction provides at least 50% of the energy of the nutritional composition, and The nutritional composition comprises an energy density of 800 kJ / 100 g to 2200 kJ / 100 g. 2. The nutritional composition according to claim 1, characterized in that the carbohydrate fraction comprises dextrose and / or maltodextrins. 3. The nutritional composition according to claim 1, characterized in that the nutritional composition comprises less than 40 g of protein per 100 g of nutritional composition. 4. The nutritional composition according to claim 1, characterized in that the nutritional composition comprises less than 20 g of fat per 100 g of nutritional composition. 5. The nutritional composition according to claim 1, characterized in that it also comprises at least one of: at least one vitamin selected from the group consisting of vitamin C, vitamin E, vitamin B12, niacin, vitamin B6, folic acid, biotin, pantothenic acid, vitamin B2, vitamin B6, and combinations thereof; at least one electrolyte or mineral selected from the group consisting of sodium, potassium, calcium, iron, magnesium, zinc, and combinations thereof; at least one amino acid selected from the group consisting of L-leucine, L-valine, L-isoleucine, and combinations thereof; Y at least one compound selected from the group consisting of flavor compounds, fiber, caffeine, guarana, acidifying agents, binding agents, gel forming materials, fruit, antioxidants, coloring agents, and combinations thereof. 6. The nutritional composition according to claim 1, characterized in that the nutritional composition is a powder. 7. The nutritional composition according to claim 1, characterized in that the nutritional composition is a liquid. 8. A packaged food product, characterized in that it comprises: an outer package that is constructed and arranged in such a way as to house a plurality of inner packages, each inner package contains a nutritional composition, the nutritional composition selected from the group consisting of those claimed in the claim 1 to claim 7. 9. The packaged food product according to claim 9, characterized in that the outer package is made from a material selected from the group consisting of cardboard, plastic, metal and combinations thereof. 10. The packaged food product according to claim 9, characterized in that the plurality of inner packages comprises from 5 to 20 inner packages. eleven . The packaged food product according to claim 9, characterized in that each of the plurality of inner packages includes a portion size of the nutritional composition. 12. A method for preparing a liquid nutritional composition, the method is characterized in that it comprises the steps of: dispensing a powdered nutritional composition from a first container into a second container, the powdered nutritional composition is selected from a group consisting of those claimed in claim 1 to claim 6; Y the combination of the powdered nutritional composition in the container with a liquid to form a liquid nutritional composition. 13. The method according to claim 12, characterized in that the liquid is selected from the group consisting of water, fruit juice, and combinations thereof. 14. The method according to claim 12, characterized in that it further comprises the step of removing the container with size for a single portion of an outer container. 15. The method according to claim 12, characterized in that the outer package is made from a material selected from the group consisting of cardboard, plastic, metal and combinations thereof. 16. The method according to claim 12, characterized in that the dispensing of a powdered nutritional composition from a first container into a second container is to empty a powdered nutritional composition from a container sized for a single portion into a container. 17. The method according to claim 12, characterized because the first container is constructed and arranged in such a way as to contain several portions of the powdered nutritional composition. 18. The method according to claim 12, characterized in that the first container comprises a food grade coating on an interior surface. 19. A method to improve performance in an individual that requires it, the method is characterized in that it comprises the steps of: administering to the individual the nutritional composition selected from the group consisting of those claimed in claim 1 to claim 7. 20. The method according to claim 19, characterized in that the performance is selected from the group consisting of athletic, academic, strength, and combinations thereof. twenty-one . The method according to claim 19, characterized in that improving performance comprises providing sustained energy to the muscles in an individual. 22. The method according to claim 19, characterized in that improving the yield comprises providing an adequate load of carbohydrates to an individual who requires it. 23. The method according to claim 22, characterized in that the individual is an athlete.