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MX2013010620A - Adenovirus de aves del serotipo 4 (fadv-4) no patogénico y vector viral del mismo. - Google Patents

Adenovirus de aves del serotipo 4 (fadv-4) no patogénico y vector viral del mismo.

Info

Publication number
MX2013010620A
MX2013010620A MX2013010620A MX2013010620A MX2013010620A MX 2013010620 A MX2013010620 A MX 2013010620A MX 2013010620 A MX2013010620 A MX 2013010620A MX 2013010620 A MX2013010620 A MX 2013010620A MX 2013010620 A MX2013010620 A MX 2013010620A
Authority
MX
Mexico
Prior art keywords
fadv
viral vector
fowl adenovirus
serotype
pathogenic serotype
Prior art date
Application number
MX2013010620A
Other languages
English (en)
Inventor
Eva Nagy
Bryan Griffin
Helena Grgic
Davor Ojkic
Original Assignee
Univ Guelph
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Guelph filed Critical Univ Guelph
Publication of MX2013010620A publication Critical patent/MX2013010620A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/235—Adenoviridae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/861—Adenoviral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02—Recovery or purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10211—Aviadenovirus, e.g. fowl adenovirus A
    • C12N2710/10221—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10211—Aviadenovirus, e.g. fowl adenovirus A
    • C12N2710/10234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10211—Aviadenovirus, e.g. fowl adenovirus A
    • C12N2710/10241—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10243—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Se describe un aislado de adenovirus aviar de alto nivel de replicación (FAdV) capaz de alcanzar un título de por lo menos 3 log10; dicho FAdV es una cepa no patogénica del serotipo 4 de adenovirus aviar, identificado como FAdV-4 ON1; adicionalmente, la presente descripción también provee un vector viral que comprende el adenovirus aviar, el cual ha insertado una secuencia nucleotídica exógena que codifica al menos un sitio antigénico de una enfermedad de interés, así como un método para obtener dicho vector viral y una composición inmunogénica que comprende el mismo.
MX2013010620A 2011-03-16 2012-03-16 Adenovirus de aves del serotipo 4 (fadv-4) no patogénico y vector viral del mismo. MX2013010620A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161453297P 2011-03-16 2011-03-16
PCT/CA2012/000238 WO2012129645A1 (en) 2011-03-16 2012-03-16 Non-pathogenic serotype 4 fowl adenovirus (fadv-4) and viral vector thereof

Publications (1)

Publication Number Publication Date
MX2013010620A true MX2013010620A (es) 2013-12-06

Family

ID=46929240

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013010620A MX2013010620A (es) 2011-03-16 2012-03-16 Adenovirus de aves del serotipo 4 (fadv-4) no patogénico y vector viral del mismo.

Country Status (4)

Country Link
US (1) US9119834B2 (es)
CA (1) CA2830305C (es)
MX (1) MX2013010620A (es)
WO (1) WO2012129645A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2830305C (en) * 2011-03-16 2020-08-25 University Of Guelph Non-pathogenic serotype 4 fowl adenovirus (fadv-4) and viral vector thereof
CN105368795B (zh) * 2015-12-14 2018-11-09 青岛易邦生物工程有限公司 一种ⅰ群4型禽腺病毒毒株及其应用
CN106771260A (zh) * 2017-03-31 2017-05-31 中国农业大学 检测血清4型禽腺病毒抗体的间接elisa试剂盒及其检测方法
CN107385110B (zh) * 2017-08-02 2018-10-23 河南农业大学 一种用于检测禽腺病毒血清4型的rpa引物及其检测方法
CN108531651A (zh) * 2018-04-13 2018-09-14 华南农业大学 一种用于检测并鉴别FAdV-4和FAdV-8b的特异性引物及其应用
CN109609698B (zh) * 2019-01-07 2022-08-16 福建省农业科学院畜牧兽医研究所 一种用于检测禽腺病毒iv型的纳米pcr试剂盒
CN110317830A (zh) * 2019-04-18 2019-10-11 肇庆大华农生物药品有限公司 一种鸭腺病毒2型dna疫苗及其制备方法和应用
CN111040024A (zh) * 2019-12-25 2020-04-21 乾元浩生物股份有限公司 4型禽腺病毒基因工程疫苗及其制备方法与应用
CN112142830B (zh) * 2020-09-18 2022-03-22 长江大学 一种重组禽腺病毒4型fiber2蛋白及其制备方法和应用
CN112626279A (zh) * 2021-01-21 2021-04-09 福建省农业科学院畜牧兽医研究所 检测新发鸭4型腺病毒的实时荧光定量pcr引物及试剂盒
CN113005101A (zh) * 2021-03-29 2021-06-22 扬州大学 一种f2部分缺失型重组血清4型禽腺病毒及其制备方法
CN113527441A (zh) * 2021-06-29 2021-10-22 广州医科大学附属第一医院（广州呼吸中心） 腺病毒抗原多肽及其应用
CN113616785A (zh) * 2021-07-01 2021-11-09 江苏省农业科学院 一种同时表达FAdV-4纤突蛋白1与纤突蛋白2基因的DNA疫苗及其构建方法和应用
CN114196786A (zh) * 2021-11-11 2022-03-18 佛山科学技术学院 禽腺病毒4型、8型双重荧光定量pcr快速检测试剂盒及方法
CN114085293B (zh) * 2021-11-14 2023-05-12 吉林大学 用于预防禽安卡拉病的重组蛋白及构建方法和应用
CN114990262B (zh) * 2022-06-20 2023-05-23 云南省畜牧兽医科学院 一种用于血清4型禽腺病毒lamp检测的引物组及其应用
CN115947798A (zh) * 2022-11-21 2023-04-11 广西壮族自治区兽医研究所 与LMH细胞免疫应答相关的蛋白质pX及其相关生物材料和应用
CN117883561B (zh) * 2023-12-12 2024-07-02 福建省农业科学院畜牧兽医研究所 一种禽腺病毒血清4型MSN-CC-Fiber2纳米颗粒疫苗的制备与应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6296852B1 (en) 1993-04-14 2001-10-02 Commonwealth Scientific And Industrial Research Organisation Recombinant avian adenovirus vector
WO2003039593A1 (en) 2001-11-08 2003-05-15 Akzo Nobel N.V. Fowl adenovirus vaccine
AU2006236910B2 (en) 2005-04-11 2012-06-07 Purdue Research Foundation Vaccine against pandemic strains of influenza viruses
US20100150958A1 (en) 2008-12-15 2010-06-17 Vectogen Pty Ltd. Methods and Compositions for Use of a Coccidiosis Vaccine
CA2830305C (en) * 2011-03-16 2020-08-25 University Of Guelph Non-pathogenic serotype 4 fowl adenovirus (fadv-4) and viral vector thereof

Also Published As

Publication number Publication date
US20140010834A1 (en) 2014-01-09
CA2830305A1 (en) 2012-10-04
US9119834B2 (en) 2015-09-01
CA2830305C (en) 2020-08-25
WO2012129645A1 (en) 2012-10-04

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