MX2013009805A - Preparación de sales de guanidina bicíclica en un medio acuoso. - Google Patents
Preparación de sales de guanidina bicíclica en un medio acuoso.Info
- Publication number
- MX2013009805A MX2013009805A MX2013009805A MX2013009805A MX2013009805A MX 2013009805 A MX2013009805 A MX 2013009805A MX 2013009805 A MX2013009805 A MX 2013009805A MX 2013009805 A MX2013009805 A MX 2013009805A MX 2013009805 A MX2013009805 A MX 2013009805A
- Authority
- MX
- Mexico
- Prior art keywords
- bicyclic guanidine
- preparation
- aqueous media
- guanidine salts
- bicyclic
- Prior art date
Links
- -1 bicyclic guanidine salts Chemical class 0.000 title abstract 3
- 239000012736 aqueous medium Substances 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- GKQPCPXONLDCMU-CCEZHUSRSA-N lacidipine Chemical compound CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1C1=CC=CC=C1\C=C\C(=O)OC(C)(C)C GKQPCPXONLDCMU-CCEZHUSRSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Paints Or Removers (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
En la presente se describen sales de guanidina bicíclica formadas como el producto de reacción de reactivos que comprenden (a) un compuesto que tiene la fórmula general CXn, en donde X es N, O o S y en donde n es de 2 a 4; (b) un ácido; (c) dipropileno triamina; y (d) agua, y un método asociado para formar una sal de guanidina bicíclica a partir de los mismos ingredientes de reacción.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/035,048 US8563560B2 (en) | 2011-02-25 | 2011-02-25 | Preparation of bicyclic guanidine salts in an aqueous media |
| PCT/US2012/026144 WO2012116080A1 (en) | 2011-02-25 | 2012-02-22 | Preparation of bicyclic guanidine salts in an aqueous media |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013009805A true MX2013009805A (es) | 2013-12-12 |
| MX348977B MX348977B (es) | 2017-07-04 |
Family
ID=45815974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013009805A MX348977B (es) | 2011-02-25 | 2012-02-22 | Preparación de sales de guanidina bicíclica en un medio acuoso. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8563560B2 (es) |
| EP (1) | EP2678340B1 (es) |
| KR (1) | KR101546172B1 (es) |
| CN (1) | CN103459393B (es) |
| CA (1) | CA2828210C (es) |
| ES (1) | ES2657065T3 (es) |
| MX (1) | MX348977B (es) |
| RU (1) | RU2563242C2 (es) |
| WO (1) | WO2012116080A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5766716B2 (ja) | 2009-12-24 | 2015-08-19 | ノボマー, インコーポレイテッド | 多環式グアニジン化合物の合成のための方法 |
| US20130289273A1 (en) * | 2012-04-25 | 2013-10-31 | Ppg Industries Ohio, Inc. | Methods for producing 1,5,7-triazabicyclo[4.4.0]dec-5-ene by reaction of a disubstituted carbodiimide and dipropylene triamine |
| US9108968B2 (en) | 2012-04-25 | 2015-08-18 | Ppg Industries Ohio, Inc. | Methods for producing 1,5,7-triazabicyclo[4.4.0]dec-5-ene by reaction of a disubstituted carbodiimide and dipropylene triamine |
| US9068089B2 (en) | 2013-03-15 | 2015-06-30 | Ppg Industries Ohio, Inc. | Phenolic admix for electrodepositable coating composition containing a cyclic guanidine |
| CN103172639B (zh) * | 2013-03-18 | 2015-08-12 | 惠州市莱佛士制药技术有限公司 | 一种基于盐酸胍的六元二环胍的制备方法 |
| US9688874B2 (en) | 2013-10-25 | 2017-06-27 | Ppg Industries Ohio, Inc. | Method of making a bicyclic guanidine-cured acrylic coating |
| CN103539798A (zh) * | 2013-11-12 | 2014-01-29 | 南京大学 | 一种双环胍(1,5,7-三氮杂双环[5.5.0]癸-5-烯)的合成方法 |
| CN104844608B (zh) * | 2015-04-13 | 2017-09-19 | 南京大学 | 相转移催化法合成双环胍tbd的工艺方法 |
| CN107325102B (zh) * | 2017-08-11 | 2019-11-12 | 南京大学 | 自催化双亲混合溶剂中合成1,5,7-三氮杂双环[4.4.0]癸-5-烯的工艺方法 |
| FI129024B (en) | 2017-11-08 | 2021-05-14 | Helsingin Yliopisto | Process for the preparation of bicyclic guanidine and its derivatives |
| WO2020048604A1 (de) * | 2018-09-06 | 2020-03-12 | Wacker Chemie Ag | Verfahren zur herstellung bicyclischer guanidine |
| WO2025045680A1 (en) * | 2023-08-25 | 2025-03-06 | Evonik Operations Gmbh | Method to make bicyclic guanidines |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2473111A (en) | 1949-06-14 | Process for production of z-amino | ||
| US3909200A (en) | 1967-05-22 | 1975-09-30 | Petrolite Corp | Use of guanidine derived compounds as corrosion inhibitors |
| US3724386A (en) | 1970-06-24 | 1973-04-03 | Us Air Force | Ablative nose tips and method for their manufacture |
| US3828122A (en) | 1970-09-29 | 1974-08-06 | Bendix Corp | Tv area correlation tracker |
| DE2118261A1 (de) | 1971-04-15 | 1972-11-02 | C.H. Boehringer Sohn, 6507 Ingelheim | Neue N-haltige Bicyclen, deren Säureadditionssalze sowie Verfahren zu deren Herstellung |
| US3865836A (en) * | 1972-12-08 | 1975-02-11 | Janssen Pharmaceutica Nv | Bicyclic imidazoles |
| DE2508188A1 (de) | 1975-02-26 | 1976-09-09 | Kalk Chemische Fabrik Gmbh | Bis-(guanidinium)-tetrabromdian und verfahren zu dessen herstellung |
| DE2914085A1 (de) | 1979-04-07 | 1980-10-16 | Basf Ag | Additionsprodukt und seine verwendung |
| GB8402995D0 (en) | 1984-02-04 | 1984-03-07 | Bp Chem Int Ltd | Transesterification process |
| GB8509531D0 (en) | 1985-04-13 | 1985-05-15 | Bp Chem Int Ltd | Preparation of guanidines |
| IT1204359B (it) | 1986-05-29 | 1989-03-01 | Enichem Sintesi | Composizioni elestomeriche fluide,reticolabili all'umidita' ambientale,adatte per l'uso in sigillanti |
| IE60275B1 (en) | 1987-06-19 | 1994-06-29 | Loctite Ireland Ltd | Diazabicyclo and triazabicyclo primer compositions and use thereof in bonding non-polar substrates |
| US4874822A (en) | 1988-04-07 | 1989-10-17 | Minnesota Mining And Manufacturing Company | Process for the acrylamidoacylation of alcohols |
| JPH0633332B2 (ja) | 1989-01-19 | 1994-05-02 | 松下電工株式会社 | 半導体封止用エポキシ樹脂成形材料 |
| IT1230705B (it) | 1989-01-27 | 1991-10-29 | Boston Spa | Composizione di hot melt reticolabile |
| US5149806A (en) | 1990-03-28 | 1992-09-22 | Minnesota Mining And Manufacturing Company | Azlactone michael adducts |
| US5268473A (en) | 1990-03-28 | 1993-12-07 | Minnesota Mining And Manufacturing Company | Azlactone Michael adducts |
| GB9201642D0 (en) | 1992-01-25 | 1992-03-11 | Ciba Geigy | Corrosion inhibitors |
| US5506279A (en) | 1993-10-13 | 1996-04-09 | Minnesota Mining And Manufacturing Company | Acrylamido functional disubstituted acetyl aryl ketone photoinitiators |
| KR970704849A (ko) | 1994-07-29 | 1997-09-06 | 워렌 리차드 보비 | 가교 점탄성 물질로 경화가능한 아크릴 시럽 |
| US5659011A (en) | 1994-09-23 | 1997-08-19 | Waldmann; John J. | Agents having high nitrogen content and high cationic charge based on dicyanimide dicyandiamide or guanidine and inorganic ammonium salts |
| EP0837844B1 (en) | 1995-07-28 | 2000-04-05 | Minnesota Mining And Manufacturing Company | Acrylamide derivatives as chromophoric photocrosslinking compound |
| FR2756282B1 (fr) * | 1996-11-22 | 1998-12-31 | Elf Aquitaine | Procede de synthese d'esters de l'acide mercapto-3-propionique |
| US6075065A (en) | 1996-12-20 | 2000-06-13 | Takeda Chemical Industries, Ltd. | Photocurable resin composition and a method for producing the same |
| JPH10180950A (ja) | 1996-12-25 | 1998-07-07 | Lintec Corp | 防眩性ハードコートフィルム及びその製造方法 |
| JPH10265612A (ja) | 1997-03-24 | 1998-10-06 | Toray Ind Inc | 硬化性組成物 |
| JPH1111986A (ja) | 1997-04-25 | 1999-01-19 | Takeda Chem Ind Ltd | 光ファイバ被覆用樹脂組成物 |
| JPH1121352A (ja) | 1997-07-03 | 1999-01-26 | Toray Ind Inc | 硬化性組成物 |
| GB9722447D0 (en) | 1997-10-23 | 1997-12-24 | Borealis As | Process |
| US6465467B1 (en) | 1999-05-21 | 2002-10-15 | Biovitrum Ab | Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases |
| US6617399B2 (en) | 1999-12-17 | 2003-09-09 | Henkel Loctite Corporation | Thermosetting resin compositions comprising epoxy resins, adhesion promoters, curatives based on the combination of nitrogen compounds and transition metal complexes, and polysulfide tougheners |
| US7012120B2 (en) | 2000-03-31 | 2006-03-14 | Henkel Corporation | Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent |
| US20050288458A1 (en) | 2002-07-29 | 2005-12-29 | Klemarczyk Philip T | Reworkable thermosetting resin composition |
| IE20000440A1 (en) | 2000-05-31 | 2003-04-02 | Loctite R & D Ltd | Semi-Solid one- or two-part compositions |
| IE20000439A1 (en) | 2000-05-31 | 2003-04-02 | Loctite R & D Ltd | Semi-Solid Primer Compositions |
| JP2002273280A (ja) | 2001-03-15 | 2002-09-24 | Honda Motor Co Ltd | シーラー塗布装置 |
| US6635690B2 (en) | 2001-06-19 | 2003-10-21 | 3M Innovative Properties Company | Reactive oligomers |
| US6550260B1 (en) | 2001-09-28 | 2003-04-22 | Carrier Corporation | Vibration detection in a transport refrigeration system through current sensing |
| US6743921B2 (en) | 2002-01-24 | 2004-06-01 | Dsm Catalytica Pharmaceuticals, Inc. | Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-1-propanol compounds |
| US7211616B2 (en) | 2002-02-14 | 2007-05-01 | The Glidden Company | Moisture curable adhesive |
| US7569634B2 (en) | 2002-02-14 | 2009-08-04 | The Glidden Company | Curable adhesive composition, adhesive kit and method of adhering substrates |
| FR2838048B1 (fr) | 2002-04-03 | 2005-05-27 | Prod Dentaires Pierre Rolland | Produit dentaire reticulable/dereticulable |
| US6936641B2 (en) | 2002-06-25 | 2005-08-30 | Johnson & Johnson Vision Care, Inc. | Macromer forming catalysts |
| US20040063848A1 (en) | 2002-09-12 | 2004-04-01 | 3M Innovative Properties Company | Oligomeric dyes and preparation thereof |
| US20040059044A1 (en) | 2002-09-12 | 2004-03-25 | 3M Innovative Properties Company | Oligomeric dyes and use thereof |
| US6894082B2 (en) | 2002-09-16 | 2005-05-17 | Henkel Corporation | Foamable compositions |
| US20050288457A1 (en) | 2002-10-22 | 2005-12-29 | Puwei Liu | Co-curable compositions |
| US7384984B2 (en) | 2003-12-10 | 2008-06-10 | 3M Innovative Properties Company | Reactive hydrophilic oligomers |
| JP4690329B2 (ja) | 2004-08-11 | 2011-06-01 | コニシ株式会社 | 反応性ホットメルト樹脂組成物及び反応性ホットメルト接着剤 |
| US20060068198A1 (en) | 2004-09-02 | 2006-03-30 | Bratys Dan M | Composite films and process for making the same |
| CA2578219C (en) | 2004-09-02 | 2011-12-20 | Ppg Industries Ohio, Inc. | Multi-component coatings that include polyurea coating layers |
| US7387819B2 (en) | 2005-01-10 | 2008-06-17 | Ppg Industries Ohio, Inc. | Method and apparatus for repairing bed-liner coatings |
| JP4592427B2 (ja) | 2005-01-18 | 2010-12-01 | コニシ株式会社 | 硬化性シリコーン系樹脂の硬化触媒、及び硬化性シリコーン系樹脂組成物 |
| US20070048504A1 (en) | 2005-08-25 | 2007-03-01 | Dimario Joseph | Methods for applying sound dampening and/or aesthetic coatings and articles made thereby |
| US7658967B2 (en) | 2005-08-25 | 2010-02-09 | Pittsburgh Glass Works, Llc | Methods for applying sound dampening and/or aesthetic coatings and articles made thereby |
| US8013080B2 (en) | 2005-09-30 | 2011-09-06 | Kaneka Corporation | Curable composition |
| DE102006056311B4 (de) | 2006-11-29 | 2018-03-01 | Alzchem Trostberg Gmbh | Verwendung von Guanidin-Derivaten als Beschleuniger bei der Härtung von Epoxidharzsystemen |
| US7842762B2 (en) | 2007-08-08 | 2010-11-30 | Ppg Industries Ohio, Inc. | Electrodepositable coating composition containing a cyclic guanidine |
| WO2009027186A2 (de) | 2007-08-29 | 2009-03-05 | Basf Se | Hyperverzweigte polymere mit guanidineinheiten |
| US8334380B2 (en) | 2008-05-09 | 2012-12-18 | Ppg Industries Ohio, Inc. | Method for producing bicyclic guanidines by use of a cyclic urea and a dehydrating agent |
| US8039618B2 (en) | 2008-05-09 | 2011-10-18 | Ppg Industries Ohio, Inc. | Method for producing bicyclic guanidines by use of a cyclic urea |
| US8492542B2 (en) | 2008-05-15 | 2013-07-23 | Ppg Industries Ohio, Inc. | Method for producing bicyclic guanidines by use of a cyclic thiourea |
| JP5766716B2 (ja) | 2009-12-24 | 2015-08-19 | ノボマー, インコーポレイテッド | 多環式グアニジン化合物の合成のための方法 |
| US8148490B2 (en) * | 2010-03-10 | 2012-04-03 | Ppg Industries Ohio, Inc. | Method of making a cyclic guanidine from a guanidinium salt and a weak acid and coating compositions containing the same |
-
2011
- 2011-02-25 US US13/035,048 patent/US8563560B2/en active Active
-
2012
- 2012-02-22 CN CN201280015303.XA patent/CN103459393B/zh active Active
- 2012-02-22 RU RU2013143297/04A patent/RU2563242C2/ru active
- 2012-02-22 WO PCT/US2012/026144 patent/WO2012116080A1/en not_active Ceased
- 2012-02-22 CA CA2828210A patent/CA2828210C/en active Active
- 2012-02-22 KR KR1020137025052A patent/KR101546172B1/ko active Active
- 2012-02-22 MX MX2013009805A patent/MX348977B/es active IP Right Grant
- 2012-02-22 ES ES12708445.7T patent/ES2657065T3/es active Active
- 2012-02-22 EP EP12708445.7A patent/EP2678340B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN103459393A (zh) | 2013-12-18 |
| WO2012116080A1 (en) | 2012-08-30 |
| EP2678340B1 (en) | 2017-11-08 |
| CA2828210C (en) | 2016-01-19 |
| US8563560B2 (en) | 2013-10-22 |
| CA2828210A1 (en) | 2012-08-30 |
| RU2563242C2 (ru) | 2015-09-20 |
| KR101546172B1 (ko) | 2015-08-20 |
| CN103459393B (zh) | 2017-06-20 |
| US20120220770A1 (en) | 2012-08-30 |
| KR20130132617A (ko) | 2013-12-04 |
| EP2678340A1 (en) | 2014-01-01 |
| MX348977B (es) | 2017-07-04 |
| ES2657065T3 (es) | 2018-03-01 |
| RU2013143297A (ru) | 2015-04-10 |
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