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MX2013008988A - Microorganismo y metodos para la biosintesis de butadieno. - Google Patents

Microorganismo y metodos para la biosintesis de butadieno.

Info

Publication number
MX2013008988A
MX2013008988A MX2013008988A MX2013008988A MX2013008988A MX 2013008988 A MX2013008988 A MX 2013008988A MX 2013008988 A MX2013008988 A MX 2013008988A MX 2013008988 A MX2013008988 A MX 2013008988A MX 2013008988 A MX2013008988 A MX 2013008988A
Authority
MX
Mexico
Prior art keywords
butadiene
naturally occurring
occurring microbial
methods
biosynthesis
Prior art date
Application number
MX2013008988A
Other languages
English (en)
Other versions
MX348334B (es
Inventor
Robin E Osterhout
Priti Pharkya
Mark J Burk
Anthony P Burgard
Sunjun
Original Assignee
Genomatica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica Inc filed Critical Genomatica Inc
Publication of MX2013008988A publication Critical patent/MX2013008988A/es
Publication of MX348334B publication Critical patent/MX348334B/es

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    • C—CHEMISTRY; METALLURGY
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    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C07C1/20—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms
    • C07C1/24—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms by elimination of water
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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    • C12P7/00—Preparation of oxygen-containing organic compounds
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    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01036—Acetoacetyl-CoA reductase (1.1.1.36)
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    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
    • C12Y103/01008—Acyl-CoA dehydrogenase (NADP+) (1.3.1.8)
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    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/08—Oxidoreductases acting on the CH-CH group of donors (1.3) with flavin as acceptor (1.3.8)
    • C12Y103/08006—Glutaryl-CoA dehydrogenase (1.3.8.6)
    • C—CHEMISTRY; METALLURGY
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    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/99—Oxidoreductases acting on the CH-CH group of donors (1.3) with other acceptors (1.3.99)
    • C12Y103/99032—Glutaryl-CoA dehydrogenase (non-decarboxylating) (1.3.99.32)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01009—Acetyl-CoA C-acetyltransferase (2.3.1.9)
    • C—CHEMISTRY; METALLURGY
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    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/0107—Glutaconyl-CoA decarboxylase (4.1.1.70)
    • C—CHEMISTRY; METALLURGY
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    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01055—3-Hydroxybutyryl-CoA dehydratase (4.2.1.55)
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    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/0112—4-Hydroxybutanoyl-CoA dehydratase (4.2.1.120)
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    • C12Y403/01—Ammonia-lyases (4.3.1)
    • C12Y403/01014—3-Aminobutyryl-CoA ammonia-lyase (4.3.1.14)
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
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  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La invención provee organismos microbianos no naturales que tienen una ruta de butadieno. Adicionalmente, la invención provee métodos de uso de dichos organismos para producir butadieno. En algunos aspectos las modalidades descritas en la presente se refieren a un procedimiento de producción de butadieno que incluye: (a) cultivar por fermentación, en una cantidad suficiente de nutrientes y medio, un organismo microbiano no natural que produce alcohol crotílico; y (b) convertir en butadieno el alcohol crotílico producido cultivando el organismo microbiano no natural.
MX2013008988A 2011-02-02 2012-02-02 Microorganismo y metodos para la biosintesis de butadieno. MX348334B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161438947P 2011-02-02 2011-02-02
PCT/US2012/023632 WO2012106516A1 (en) 2011-02-02 2012-02-02 Microorganisms and methods for the biosynthesis of butadiene

Publications (2)

Publication Number Publication Date
MX2013008988A true MX2013008988A (es) 2014-03-21
MX348334B MX348334B (es) 2017-06-07

Family

ID=46603080

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013008988A MX348334B (es) 2011-02-02 2012-02-02 Microorganismo y metodos para la biosintesis de butadieno.

Country Status (13)

Country Link
US (4) US9321701B2 (es)
EP (1) EP2670852A4 (es)
JP (3) JP5960729B2 (es)
KR (1) KR20140145935A (es)
CN (2) CN106191132A (es)
AU (1) AU2012212118B2 (es)
BR (1) BR112013019811A2 (es)
CA (1) CA2826293A1 (es)
MX (1) MX348334B (es)
MY (2) MY162964A (es)
PH (1) PH12013501630A1 (es)
SG (1) SG192614A1 (es)
WO (1) WO2012106516A1 (es)

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JP2012529889A (ja) 2009-06-10 2012-11-29 ゲノマチカ， インク． Ｍｅｋ及び２−ブタノールの炭素効率のよい生合成のための微生物及び方法
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CN103080324B (zh) 2010-05-05 2019-03-08 基因组股份公司 用于丁二烯生物合成的微生物和方法
BR112013019811A2 (pt) * 2011-02-02 2017-02-21 Genomatica Inc processo para a produção de butadieno e organismo microbiano que não ocorre naturalmente.
US9422578B2 (en) 2011-06-17 2016-08-23 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
BR112013032516A2 (pt) 2011-06-17 2017-03-01 Invista Tech Sarl método de biosintetizar butadieno e método para produzir butadieno
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BR112016002626A2 (pt) 2013-08-05 2017-09-12 Invista Tech Sarl método para sintetizar isobuteno e hospedeiro recombinante
BR112016002625A2 (pt) 2013-08-05 2017-09-12 Invista Tech Sarl método para sintetizar enzimaticamente isopreno e hospedeiro recombinante produtor de isopreno
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CN104298866B (zh) * 2014-09-30 2017-06-06 杭州电子科技大学 一种克劳斯硫磺回收过程中反应炉动态建模方法
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