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MX2013005624A - Nuevos derivados de indolizina, su preparacion y su aplicacion en terapeutica. - Google Patents

Nuevos derivados de indolizina, su preparacion y su aplicacion en terapeutica.

Info

Publication number
MX2013005624A
MX2013005624A MX2013005624A MX2013005624A MX2013005624A MX 2013005624 A MX2013005624 A MX 2013005624A MX 2013005624 A MX2013005624 A MX 2013005624A MX 2013005624 A MX2013005624 A MX 2013005624A MX 2013005624 A MX2013005624 A MX 2013005624A
Authority
MX
Mexico
Prior art keywords
therapeutic use
preparation
indolizine derivatives
novel indolizine
novel
Prior art date
Application number
MX2013005624A
Other languages
English (en)
Inventor
Jean-Michel Altenburger
Franck Caussanel
Sergio Mallart
Marie-Claire Philippo-Orts
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MX2013005624A publication Critical patent/MX2013005624A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invención tiene por objeto derivados de indolizina de fórmula general (I), donde A, B, m, W, n y R2 son como se definen en la reivindicación 1, así como su procedimiento de preparación y su aplicación en terapéutica.
MX2013005624A 2010-11-17 2011-11-16 Nuevos derivados de indolizina, su preparacion y su aplicacion en terapeutica. MX2013005624A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1059445A FR2967412B1 (fr) 2010-11-17 2010-11-17 Nouveaux derives d'indolizine, leur preparation et leur application en therapeutique
PCT/FR2011/052661 WO2012066234A1 (fr) 2010-11-17 2011-11-16 Nouveaux derives d'indolizine, leur préparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
MX2013005624A true MX2013005624A (es) 2013-07-05

Family

ID=43923771

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013005624A MX2013005624A (es) 2010-11-17 2011-11-16 Nuevos derivados de indolizina, su preparacion y su aplicacion en terapeutica.

Country Status (14)

Country Link
US (1) US20130245006A1 (es)
EP (1) EP2640724A1 (es)
JP (1) JP2014500256A (es)
KR (1) KR20140014082A (es)
CN (1) CN103313986A (es)
AU (1) AU2011330996A1 (es)
BR (1) BR112013012300A2 (es)
CA (1) CA2818279A1 (es)
FR (1) FR2967412B1 (es)
IL (1) IL226388A0 (es)
MX (1) MX2013005624A (es)
RU (1) RU2013127239A (es)
SG (1) SG190825A1 (es)
WO (1) WO2012066234A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11919860B1 (en) 2023-10-06 2024-03-05 King Faisal University 1-2(-(substituted phenyl)-2-oxoethyl)-4-(isopropoxycarbonyl)pyridin-1-ium bromides as anti-tubercular agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI61030C (fi) 1976-02-19 1982-05-10 Sanofi Sa Foerfarande foer framstaellning av terapeutiskt verkande 2-substituerade-1- eller 3-benzoyl-indolizinderivat
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
FR2838123B1 (fr) * 2002-04-04 2005-06-10 Sanofi Synthelabo Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf
FR2859997B1 (fr) * 2003-09-18 2006-02-03 Sanofi Synthelabo Nouveaux derives d'indolizine 1,2,3,6,7,8 substituee, inhibiteurs des fgfs, leur procede de preparation et les compositions pharmaceutiques les contenant.
FR2883286B1 (fr) * 2005-03-16 2008-10-03 Sanofi Aventis Sa NOUVEAUX DERIVES D'IMIDAZO[1,5-a]PYRIDINES, INHIBITEURS DE FGFs, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT

Also Published As

Publication number Publication date
BR112013012300A2 (pt) 2016-08-16
JP2014500256A (ja) 2014-01-09
WO2012066234A9 (fr) 2012-11-01
EP2640724A1 (fr) 2013-09-25
AU2011330996A1 (en) 2013-06-06
RU2013127239A (ru) 2014-12-27
KR20140014082A (ko) 2014-02-05
FR2967412B1 (fr) 2012-12-14
US20130245006A1 (en) 2013-09-19
IL226388A0 (en) 2013-07-31
FR2967412A1 (fr) 2012-05-18
WO2012066234A1 (fr) 2012-05-24
CN103313986A (zh) 2013-09-18
CA2818279A1 (fr) 2012-05-24
SG190825A1 (en) 2013-07-31

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Legal Events

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FA Abandonment or withdrawal