MX2013005560A - Cloracion de baja temperatura de carbohidratos. - Google Patents
Cloracion de baja temperatura de carbohidratos.Info
- Publication number
- MX2013005560A MX2013005560A MX2013005560A MX2013005560A MX2013005560A MX 2013005560 A MX2013005560 A MX 2013005560A MX 2013005560 A MX2013005560 A MX 2013005560A MX 2013005560 A MX2013005560 A MX 2013005560A MX 2013005560 A MX2013005560 A MX 2013005560A
- Authority
- MX
- Mexico
- Prior art keywords
- irreversible
- carbohydrates
- low temperature
- tgs
- derivative
- Prior art date
Links
- 150000001720 carbohydrates Chemical class 0.000 title abstract 3
- 238000005660 chlorination reaction Methods 0.000 title abstract 2
- 235000014633 carbohydrates Nutrition 0.000 title 1
- 230000002427 irreversible effect Effects 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 239000004376 Sucralose Substances 0.000 abstract 1
- 239000008122 artificial sweetener Substances 0.000 abstract 1
- 235000021311 artificial sweeteners Nutrition 0.000 abstract 1
- 238000001311 chemical methods and process Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000007257 deesterification reaction Methods 0.000 abstract 1
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 abstract 1
- 235000019408 sucralose Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/33—Artificial sweetening agents containing sugars or derivatives
- A23L27/37—Halogenated sugars
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/24—Non-sugar sweeteners
- A23V2250/264—Sucralose, halogenated sugar
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
Abstract
Se presente un método para dorar un carbohidrato o su derivado, por ejemplo, un sucrosa - 6 - éster en las posiciones 4,1', y 6', con remoción irreversible de HCI formado durante la reacción para formar el carbohidrato o su derivado dorado, por ejemplo, un 4,1',6' - tricloro - 4,1',6' - trideoxi - 6 - O - éster de galactosucrosa (TGS-6E). La remoción irreversible de HCI se puede realizar mediante un proceso físico irreversible y/o un proceso químico irreversible. Sucralosa, un endulzante artificial, se puede preparar mediante la de - esterificación de TGS-6E. La reacción de cloración toma lugar a bajas temperaturas y el producto dorado deseado se obtiene en elevada producción y con nivel elevado de pureza.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41667410P | 2010-11-23 | 2010-11-23 | |
| PCT/US2011/061796 WO2012071385A1 (en) | 2010-11-23 | 2011-11-22 | Low temperature chlorination of carbohydrates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2013005560A true MX2013005560A (es) | 2013-08-26 |
Family
ID=45422352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013005560A MX2013005560A (es) | 2010-11-23 | 2011-11-22 | Cloracion de baja temperatura de carbohidratos. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8729255B2 (es) |
| EP (1) | EP2643338B1 (es) |
| CN (1) | CN103298824B (es) |
| AU (1) | AU2011332011B2 (es) |
| CA (1) | CA2817630C (es) |
| MX (1) | MX2013005560A (es) |
| SG (1) | SG190083A1 (es) |
| WO (1) | WO2012071385A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2013005560A (es) | 2010-11-23 | 2013-08-26 | Lexington Pharmaceuticals Lab Llc | Cloracion de baja temperatura de carbohidratos. |
| HUE027876T2 (en) | 2011-10-14 | 2016-10-28 | Lexington Pharmaceuticals Laboratories Llc | Carbohydrate chlorination and carbohydrate derivatives |
| CN103145772A (zh) * | 2013-03-26 | 2013-06-12 | 山东金城柯瑞化学有限公司 | 三氯蔗糖的制备方法 |
| WO2015092374A1 (en) | 2013-12-16 | 2015-06-25 | Tate & Lyle Technology Limited | Chlorination of sucrose-6-esters |
| CN103965266A (zh) * | 2014-04-22 | 2014-08-06 | 南通市常海食品添加剂有限公司 | 三氯蔗糖制备中氯化滴加控制方法 |
| WO2016020635A1 (en) | 2014-08-08 | 2016-02-11 | Tate & Lyle Technology Limited | Chlorination of sucrose-6-esters |
| GB2536480B (en) | 2015-03-17 | 2019-09-04 | Tate & Lyle Tech Ltd | DMF Distillation |
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| US4435440A (en) | 1976-01-08 | 1984-03-06 | Tate & Lyle Limited | Sweeteners |
| EP0043649B1 (en) * | 1980-07-08 | 1984-09-12 | TATE & LYLE PUBLIC LIMITED COMPANY | Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (tgs) |
| JPS60258171A (ja) | 1984-06-04 | 1985-12-20 | Showa Denko Kk | エピクロルヒドリンの製造方法 |
| US4762537A (en) | 1985-11-07 | 1988-08-09 | Aluminum Company Of America | Adsorbent for HCl comprising alumina and acid-treated Y zeolite |
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| US4980463A (en) * | 1989-07-18 | 1990-12-25 | Noramco, Inc. | Sucrose-6-ester chlorination |
| US5136031A (en) * | 1990-07-09 | 1992-08-04 | Tate & Lyle Public Limited Company | Chlorination of sugars |
| US5498709A (en) | 1994-10-17 | 1996-03-12 | Mcneil-Ppc, Inc. | Production of sucralose without intermediate isolation of crystalline sucralose-6-ester |
| US6206950B1 (en) | 1998-10-29 | 2001-03-27 | Cargill, Incorporated | Process for recovery of aluminum using high purity salt aluminum flux |
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| US6860985B2 (en) | 2001-12-12 | 2005-03-01 | Exxonmobil Research And Engineering Company | Process for increasing yield in coking processes |
| US6831181B2 (en) | 2002-04-17 | 2004-12-14 | E. I. Dupont De Nemours And Co. | High yield byproduct recycle process for anhydro sugar alcohols |
| TWI314153B (en) * | 2002-07-12 | 2009-09-01 | Mitsui Chemicals Inc | Process for production of oxyalkylene derivative |
| US20040030124A1 (en) | 2002-08-06 | 2004-02-12 | Catani Steven J. | Process for recovering chlorosucrose compounds |
| JP2004143047A (ja) | 2002-10-22 | 2004-05-20 | Daicel Chem Ind Ltd | ε−カプロラクトンの製造方法 |
| US7425258B2 (en) | 2003-02-28 | 2008-09-16 | Exxonmobil Research And Engineering Company | C6 recycle for propylene generation in a fluid catalytic cracking unit |
| CA2537804A1 (en) | 2003-09-05 | 2005-03-17 | Teva Pharmaceutical Industries Ltd | A recycling process for preparing sertraline |
| US7258885B2 (en) | 2004-03-01 | 2007-08-21 | Tasty-Trim, Inc. | Flavored artificial sweetener |
| EP1735327B1 (en) | 2004-03-19 | 2011-05-04 | V.B. Medicare Pvt. Ltd. | An improved process for producing chlorinated sucrose |
| WO2006061855A2 (en) | 2004-12-10 | 2006-06-15 | Pharmed Medicare Private Limited | Salts assisted selective extraction of 6-acetyl-4.1', 6' trichlorogalactosucrose and 4, 1 ', 6' trichlorogalactosucrose from aqueous reaction mixture |
| US20090105470A1 (en) | 2005-02-22 | 2009-04-23 | Pharmed Medicare Private Limited , A Corporation | Tin Mediated Regioselective Synthesis of Sucrose-6-Esters |
| WO2006117799A2 (en) | 2005-02-22 | 2006-11-09 | Pharmed Medicare Private Limited | Molecular separation process in various steps of process for production of chlorinated sugars, their precursors and derivatives |
| CN101490070A (zh) | 2005-05-04 | 2009-07-22 | V.B.医疗保险私人有限公司 | 由五氯化磷和dmf产生副产物磷酰氯以及其通过转变成vilsmeier-haack试剂在氯化反应中的应用 |
| CN101253189A (zh) | 2005-08-30 | 2008-08-27 | 法马德医疗保险私人有限公司 | 基于从反应混合物中直接萃取到有机溶剂中随后蒸除溶剂的纯化三氯半乳蔗糖的方法 |
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| CA2623230A1 (en) | 2005-09-22 | 2007-05-18 | Pharmed Medicare Pvt. Ltd. | Use of acid scavengers in removal of protons (acidity) of the reaction mass during chlorination of sucrose-6- acetate |
| US20080300391A1 (en) | 2005-10-20 | 2008-12-04 | Rakesh Ratnam | Acid Mediated Deacylation of 6-0-Trichlorogalactosurcrose to Trich-Lorogalactosucrose |
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| US20100022765A1 (en) | 2008-07-23 | 2010-01-28 | David Losan Ho | Methods for extracting and purifying sucralose intermediate |
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| GB2468936B (en) * | 2009-03-27 | 2011-09-07 | Mohamad Rami Radwan Jaber | Chlorination of sucrose-6-esters |
| GB2471348B (en) | 2009-06-22 | 2011-12-14 | Tate & Lyle Technology Ltd | A method for producing sucralose-6-acylate |
| MX2013005560A (es) | 2010-11-23 | 2013-08-26 | Lexington Pharmaceuticals Lab Llc | Cloracion de baja temperatura de carbohidratos. |
| HUE027876T2 (en) | 2011-10-14 | 2016-10-28 | Lexington Pharmaceuticals Laboratories Llc | Carbohydrate chlorination and carbohydrate derivatives |
-
2011
- 2011-11-22 MX MX2013005560A patent/MX2013005560A/es active IP Right Grant
- 2011-11-22 SG SG2013033386A patent/SG190083A1/en unknown
- 2011-11-22 WO PCT/US2011/061796 patent/WO2012071385A1/en not_active Ceased
- 2011-11-22 CN CN201180055941.XA patent/CN103298824B/zh active Active
- 2011-11-22 EP EP11802817.4A patent/EP2643338B1/en active Active
- 2011-11-22 CA CA2817630A patent/CA2817630C/en not_active Expired - Fee Related
- 2011-11-22 AU AU2011332011A patent/AU2011332011B2/en active Active
-
2013
- 2013-03-14 US US13/826,493 patent/US8729255B2/en active Active
-
2014
- 2014-04-04 US US14/245,452 patent/US9371349B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US8729255B2 (en) | 2014-05-20 |
| AU2011332011B2 (en) | 2017-01-12 |
| SG190083A1 (en) | 2013-06-28 |
| US9371349B2 (en) | 2016-06-21 |
| EP2643338B1 (en) | 2016-04-06 |
| CA2817630A1 (en) | 2012-05-31 |
| AU2011332011A1 (en) | 2013-05-23 |
| US20140221642A1 (en) | 2014-08-07 |
| WO2012071385A1 (en) | 2012-05-31 |
| CN103298824A (zh) | 2013-09-11 |
| EP2643338A1 (en) | 2013-10-02 |
| US20130197213A1 (en) | 2013-08-01 |
| CA2817630C (en) | 2019-09-03 |
| CN103298824B (zh) | 2016-10-12 |
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Legal Events
| Date | Code | Title | Description |
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| FG | Grant or registration |