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MX2013003880A - Metodo para diagnostico, pronostico y tratamiento de la metastasis de carcer de mama. - Google Patents

Metodo para diagnostico, pronostico y tratamiento de la metastasis de carcer de mama.

Info

Publication number
MX2013003880A
MX2013003880A MX2013003880A MX2013003880A MX2013003880A MX 2013003880 A MX2013003880 A MX 2013003880A MX 2013003880 A MX2013003880 A MX 2013003880A MX 2013003880 A MX2013003880 A MX 2013003880A MX 2013003880 A MX2013003880 A MX 2013003880A
Authority
MX
Mexico
Prior art keywords
prognosis
diagnosis
metastases
treatment
metastasis
Prior art date
Application number
MX2013003880A
Other languages
English (en)
Other versions
MX344315B (es
Inventor
Roger Gomis Cabre
Maria Tarragona Sunyer
Anna Arnal Estape
Milica Pavlovic
Original Assignee
Icrea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES201031478A external-priority patent/ES2379918B1/es
Application filed by Icrea filed Critical Icrea
Publication of MX2013003880A publication Critical patent/MX2013003880A/es
Publication of MX344315B publication Critical patent/MX344315B/es

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503Five-membered rings
    • C07F9/6506Five-membered rings having the nitrogen atoms in positions 1 and 3
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hematology (AREA)

Abstract

La presente invención se relaciona con un método para el diagnóstico o el pronóstico de metástasis en cáncer de mama que comprende determinar si el gen c-MAF se encuentra 5 amplificado en una muestra de tumor primario. Asimismo, la invención también se relaciona con un método para el diagnóstico o el pronóstico de metástasis en cáncer de mama ER-, así como con un método para determinar la propensión de desarrollar metástasis a hueso frente a metástasis a otros órganos, que comprenden determinar el nivel de expresión del gen c-MAF. Por último, la invención se relaciona con el empleo de un 10 inhibidor de c-MAF como diana terapéutica para el tratamiento de la metástasis del cáncer de mama ER-.
MX2013003880A 2010-10-06 2011-10-05 Metodo para el diagnostico, pronostico y tratamiento de la metastasis de cancer de mama. MX344315B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES201031478A ES2379918B1 (es) 2010-10-06 2010-10-06 Método para el diagnóstico, pronóstico y tratamiento de la metástasis de cáncer de mama.
ES201131073 2011-06-27
PCT/ES2011/070693 WO2012045905A2 (es) 2010-10-06 2011-10-05 Método para el diagnóstico, pronóstico y tratamiento de la metástasis de cáncer de mama

Publications (2)

Publication Number Publication Date
MX2013003880A true MX2013003880A (es) 2013-12-02
MX344315B MX344315B (es) 2016-12-13

Family

ID=45099129

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013003880A MX344315B (es) 2010-10-06 2011-10-05 Metodo para el diagnostico, pronostico y tratamiento de la metastasis de cancer de mama.
MX2016016496A MX382266B (es) 2010-10-06 2011-10-05 Metodo para el diagnostico, pronostico y tratamiento de la metastasis de cancer de mama.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2016016496A MX382266B (es) 2010-10-06 2011-10-05 Metodo para el diagnostico, pronostico y tratamiento de la metastasis de cancer de mama.

Country Status (13)

Country Link
US (3) US10047398B2 (es)
EP (3) EP2626431B1 (es)
JP (5) JP6159254B2 (es)
KR (2) KR102240323B1 (es)
CN (2) CN108192972B (es)
AR (1) AR083357A1 (es)
AU (4) AU2011311452B2 (es)
BR (1) BR112013008505B1 (es)
CA (1) CA2813674C (es)
DK (2) DK2626431T3 (es)
ES (3) ES2721639T3 (es)
MX (2) MX344315B (es)
WO (1) WO2012045905A2 (es)

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HK1187377A1 (en) 2014-04-04
AU2021203599A1 (en) 2021-07-01
CN108192972A (zh) 2018-06-22
CN103339265A (zh) 2013-10-02
AR083357A1 (es) 2013-02-21
JP2019195340A (ja) 2019-11-14
WO2012045905A3 (es) 2012-06-21
BR112013008505A2 (pt) 2016-07-05
ES2911505T3 (es) 2022-05-19
MX344315B (es) 2016-12-13
JP2021192636A (ja) 2021-12-23
AU2011311452A1 (en) 2013-05-09
EP2626431B1 (en) 2015-09-16
US20140057796A1 (en) 2014-02-27
US11072831B2 (en) 2021-07-27
US20220049316A1 (en) 2022-02-17
JP2018099132A (ja) 2018-06-28
ES2562274T3 (es) 2016-03-03
AU2011311452B2 (en) 2016-09-01
BR112013008505B1 (pt) 2023-01-24
US12312642B2 (en) 2025-05-27
DK3091085T3 (da) 2019-05-06
AU2019201493B2 (en) 2021-03-11
AU2021203599B2 (en) 2024-10-10
DK2626431T3 (en) 2015-12-21
CN103339265B (zh) 2018-03-30
US10047398B2 (en) 2018-08-14
JP2017104115A (ja) 2017-06-15
US20190169693A1 (en) 2019-06-06
MX382266B (es) 2025-03-13
JP6159254B2 (ja) 2017-07-12
AU2016266009A1 (en) 2016-12-15
JP6946385B2 (ja) 2021-10-06
EP3517630A1 (en) 2019-07-31
JP6571698B2 (ja) 2019-09-04
KR101944555B1 (ko) 2019-02-01
EP3091085B1 (en) 2019-02-27
CA2813674A1 (en) 2012-04-12
KR20190009835A (ko) 2019-01-29
JP2013541339A (ja) 2013-11-14
CA2813674C (en) 2020-11-24
ES2721639T3 (es) 2019-08-02
CN108192972B (zh) 2022-09-09
KR20140071946A (ko) 2014-06-12
EP3517630B1 (en) 2022-01-19
EP3091085A1 (en) 2016-11-09
AU2019201493A1 (en) 2019-03-28
EP2626431A2 (en) 2013-08-14
WO2012045905A2 (es) 2012-04-12
KR102240323B1 (ko) 2021-04-14
AU2016266009B2 (en) 2018-12-06

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