MX2012014071A - Composicion farmaceutica estable para el tratamiento de osteoporosis. - Google Patents
Composicion farmaceutica estable para el tratamiento de osteoporosis.Info
- Publication number
- MX2012014071A MX2012014071A MX2012014071A MX2012014071A MX2012014071A MX 2012014071 A MX2012014071 A MX 2012014071A MX 2012014071 A MX2012014071 A MX 2012014071A MX 2012014071 A MX2012014071 A MX 2012014071A MX 2012014071 A MX2012014071 A MX 2012014071A
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutical composition
- stable pharmaceutical
- treating osteoporosis
- compositions
- osteoporosis
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 208000001132 Osteoporosis Diseases 0.000 title 1
- 208000006386 Bone Resorption Diseases 0.000 abstract 1
- IIDJRNMFWXDHID-UHFFFAOYSA-N Risedronic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(O)CC1=CC=CN=C1 IIDJRNMFWXDHID-UHFFFAOYSA-N 0.000 abstract 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
- 230000024279 bone resorption Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960000759 risedronic acid Drugs 0.000 abstract 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 abstract 1
- 235000005282 vitamin D3 Nutrition 0.000 abstract 1
- 239000011647 vitamin D3 Substances 0.000 abstract 1
- 229940021056 vitamin d3 Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención proporciona composiciones farmacéuticas que aumentan la biodisponibilidad de risedronato de sodio, y proporciona Vitamina D3 con una mayor estabilidad, dichas composiciones son útiles para inhibir la resorción ósea.
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2012014071A MX350569B (es) | 2012-12-03 | 2012-12-03 | Composicion farmaceutica estable para el tratamiento de osteoporosis. |
| ES13859631.7T ES2629739T3 (es) | 2012-12-03 | 2013-10-30 | Composición farmacéutica estable para el tratamiento de osteoporosis |
| PCT/MX2013/000130 WO2014088385A1 (es) | 2012-12-03 | 2013-10-30 | Composición farmacéutica estable para el tratamiento de osteoporosis |
| EP13859631.7A EP2926817B1 (en) | 2012-12-03 | 2013-10-30 | Stable pharmaceutical composition for treating osteoporosis |
| US14/647,981 US20150342968A1 (en) | 2012-12-03 | 2013-10-30 | Stable pharmaceutical composition for treating osteoporosis |
| JP2015545408A JP6374879B2 (ja) | 2012-12-03 | 2013-10-30 | 骨粗しょう症治療用の安定な医薬組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2012014071A MX350569B (es) | 2012-12-03 | 2012-12-03 | Composicion farmaceutica estable para el tratamiento de osteoporosis. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2012014071A true MX2012014071A (es) | 2014-06-23 |
| MX350569B MX350569B (es) | 2017-09-11 |
Family
ID=50883732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012014071A MX350569B (es) | 2012-12-03 | 2012-12-03 | Composicion farmaceutica estable para el tratamiento de osteoporosis. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20150342968A1 (es) |
| EP (1) | EP2926817B1 (es) |
| JP (1) | JP6374879B2 (es) |
| ES (1) | ES2629739T3 (es) |
| MX (1) | MX350569B (es) |
| WO (1) | WO2014088385A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10478498B2 (en) | 2014-06-20 | 2019-11-19 | Reform Biologics, Llc | Excipient compounds for biopolymer formulations |
| WO2015196091A1 (en) | 2014-06-20 | 2015-12-23 | Reform Biologics, Llc | Viscosity-reducing excipient compounds for protein formulations |
| WO2022056220A2 (en) * | 2020-09-11 | 2022-03-17 | Reform Biologics, Inc. | Excipient compounds for protein formulations |
| CN119385959B (zh) * | 2025-01-03 | 2025-04-01 | 山东第一医科大学附属省立医院(山东省立医院) | 一种利塞膦酸钠片剂及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04004807A (es) | 2004-05-19 | 2005-11-24 | Merck & Co Inc | Composiciones y metodos para inhibir la resorcion osea. |
| US7645460B2 (en) * | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of risedronate |
| US7645459B2 (en) * | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of bisphosphonates |
| US7473684B2 (en) | 2005-09-16 | 2009-01-06 | Selamine Limited | Bisphosphonate formulation |
| KR100822133B1 (ko) | 2006-11-06 | 2008-04-15 | 한미약품 주식회사 | 비타민 d 또는 이의 유도체의 고체분산체 및비스포스포네이트를 포함하는, 골다공증 예방 또는 치료용복합제제 |
| EP2127656A4 (en) * | 2006-12-20 | 2010-03-03 | Landsteiner Scient S A De C V | COMPOSITIONS OF RISEDRONATE AND VITAMIN D3 |
| KR100844256B1 (ko) * | 2007-03-23 | 2008-07-07 | 코오롱제약주식회사 | 리세드로네이트와 비타민 d를 포함하는 대사성 골질환치료용 약제조성물 및 이의 제조방법 |
| EP2201937A1 (en) * | 2008-12-23 | 2010-06-30 | Teva Pharmaceutical Industries Ltd. | Formulations comprising vitamin D or derivatives thereof |
| TR200900878A2 (tr) | 2009-02-05 | 2010-08-23 | Bi̇lgi̇ç Mahmut | Tek bir dozaj formunda kombine edilen farmasötik formülasyonlar |
| KR101102364B1 (ko) | 2009-09-18 | 2012-01-03 | 한림제약(주) | 비스포스포네이트 유도체 및 고용량의 콜레칼시페롤을 포함하는 약학 조성물 |
| KR20120005228A (ko) * | 2010-07-08 | 2012-01-16 | 주식회사 네비팜 | 골다공증 치료용 비스포스폰산 함유 장용 약학조성물 및 그의 제조방법 |
-
2012
- 2012-12-03 MX MX2012014071A patent/MX350569B/es active IP Right Grant
-
2013
- 2013-10-30 EP EP13859631.7A patent/EP2926817B1/en active Active
- 2013-10-30 JP JP2015545408A patent/JP6374879B2/ja active Active
- 2013-10-30 WO PCT/MX2013/000130 patent/WO2014088385A1/es not_active Ceased
- 2013-10-30 US US14/647,981 patent/US20150342968A1/en not_active Abandoned
- 2013-10-30 ES ES13859631.7T patent/ES2629739T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6374879B2 (ja) | 2018-08-15 |
| WO2014088385A1 (es) | 2014-06-12 |
| EP2926817A1 (en) | 2015-10-07 |
| ES2629739T3 (es) | 2017-08-14 |
| EP2926817B1 (en) | 2017-03-29 |
| MX350569B (es) | 2017-09-11 |
| JP2016501226A (ja) | 2016-01-18 |
| EP2926817A4 (en) | 2016-05-18 |
| US20150342968A1 (en) | 2015-12-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |