[go: up one dir, main page]

MX2012013872A - Formas de dosificacion oral de bendamustina. - Google Patents

Formas de dosificacion oral de bendamustina.

Info

Publication number
MX2012013872A
MX2012013872A MX2012013872A MX2012013872A MX2012013872A MX 2012013872 A MX2012013872 A MX 2012013872A MX 2012013872 A MX2012013872 A MX 2012013872A MX 2012013872 A MX2012013872 A MX 2012013872A MX 2012013872 A MX2012013872 A MX 2012013872A
Authority
MX
Mexico
Prior art keywords
bendamustine
dosage forms
oral dosage
pharmaceutically acceptable
solvate
Prior art date
Application number
MX2012013872A
Other languages
English (en)
Inventor
Jeffrey Colledge
Margaretha Olthoff
Original Assignee
Astellas Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44243599&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2012013872(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astellas Deutschland Gmbh filed Critical Astellas Deutschland Gmbh
Publication of MX2012013872A publication Critical patent/MX2012013872A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Composición farmacéutica oral que comprende bendamustina como ingrediente activo, o un éster, una sal o un solvato farmacéuticamente aceptable de ésta, y un excipiente farmacéuticamente aceptable que es un agente tensioactivo no iónico, hidrofílico y farmacéuticamente aceptable.
MX2012013872A 2010-06-02 2011-06-01 Formas de dosificacion oral de bendamustina. MX2012013872A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10075231 2010-06-02
EP11075047 2011-03-14
PCT/EP2011/002764 WO2011151087A1 (en) 2010-06-02 2011-06-01 Oral dosage forms of bendamustine

Publications (1)

Publication Number Publication Date
MX2012013872A true MX2012013872A (es) 2013-04-03

Family

ID=44243599

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012013872A MX2012013872A (es) 2010-06-02 2011-06-01 Formas de dosificacion oral de bendamustina.

Country Status (26)

Country Link
US (2) US20130202693A1 (es)
EP (1) EP2575784B1 (es)
JP (2) JP6209446B2 (es)
KR (1) KR101830142B1 (es)
CN (1) CN103037851A (es)
AR (1) AR081835A1 (es)
AU (1) AU2011260615B2 (es)
BR (1) BR112012030654B1 (es)
CA (1) CA2800279A1 (es)
CL (1) CL2012003341A1 (es)
CO (1) CO6640318A2 (es)
DK (1) DK2575784T3 (es)
EA (1) EA031793B1 (es)
ES (1) ES2690257T3 (es)
IL (1) IL223311B (es)
JO (1) JO3587B1 (es)
MX (1) MX2012013872A (es)
MY (1) MY173873A (es)
NZ (1) NZ603872A (es)
PH (1) PH12012502281B1 (es)
PL (1) PL2575784T3 (es)
PT (1) PT2575784T (es)
SG (1) SG186099A1 (es)
TW (1) TWI500431B (es)
WO (1) WO2011151087A1 (es)
ZA (1) ZA201208823B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2814487A4 (en) * 2012-02-14 2015-07-15 Eagle Pharmaceuticals Inc FORMULAS FROM BENDAMUSTIN
EP2641592A1 (en) 2012-03-23 2013-09-25 Salmon Pharma GmbH Pharmaceutical formulation comprising bendamustine
HRP20250525T1 (hr) * 2012-05-18 2025-06-20 Genentech, Inc. Visokokoncentrirane formulacije monoklonskog protutijela
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
SG11201503560TA (en) 2012-11-12 2015-06-29 Ignyta Inc Bendamustine derivatives and methods of using same
JP2015537029A (ja) 2012-11-14 2015-12-24 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ 生物学的に活性な物質及び不規則性無機酸化物を含有する組成物
GB201304662D0 (en) 2013-03-14 2013-05-01 Sigmoid Pharma Ltd Compositions

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE159289C (es) * 1903-10-08 1905-03-16
US20030044434A1 (en) * 1997-07-29 2003-03-06 Ping Gao Self-emulsifying formulation for lipophilic compounds
FR2781373B1 (fr) * 1998-07-07 2001-09-21 Pf Medicament Formulations thixotropes pour le remplissage de gelules
US7374779B2 (en) * 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
AU2002258013A1 (en) 2001-04-10 2002-10-28 Fakhreddin Jamali Animal model for evaluating analgesics
US20030105141A1 (en) * 2001-04-17 2003-06-05 Ping Gao Finely self-emulsifiable pharmaceutical composition
UA80682C2 (en) * 2001-08-06 2007-10-25 Pharmacia Corp Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
JP2006518380A (ja) 2003-01-31 2006-08-10 スミスクライン・ビーチャム・コーポレイション 固体分散体組成物
AU2003261633A1 (en) 2003-02-12 2004-09-06 R And P Korea Co., Ltd. Solvent system of hardly soluble drug with improved elution rate
US7871607B2 (en) * 2003-03-05 2011-01-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
AR054094A1 (es) * 2004-11-05 2007-06-06 Cephalon Inc Tratamientos de cancer
CN101052396A (zh) * 2004-11-05 2007-10-10 赛福伦公司 癌症治疗
EP1674082A1 (de) * 2004-12-22 2006-06-28 Zentaris GmbH Verfahren zur Herstellung von sterilen Suspensionen oder Lyophilisaten schwerlöslicher basischer Peptidkomplexe, diese enthaltende pharmazeutische Formulierungen sowie ihre Verwendung als Arzneimittel
US8436190B2 (en) * 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
GB0526419D0 (en) 2005-12-23 2006-02-08 Cyclacel Ltd Formulation
RU2009103000A (ru) * 2006-06-30 2010-08-10 МакНЕЙЛ-ППС, ИНК. (US) Твердые капсулы, наполненные жидкостью, содержащей ибупрофен
AU2008237246B2 (en) * 2007-04-05 2014-06-05 University Of Kansas Rapidly dissolving pharmaceutical compositions comprising pullulan
CA2692977A1 (en) * 2007-07-12 2009-01-15 Tragara Pharmaceuticals, Inc. Methods and compositions for the treatment of cancer, tumors, and tumor-related disorders
CN101809024A (zh) * 2007-07-16 2010-08-18 铂雅制药公司 吡铂的口服制剂
KR100913644B1 (ko) 2007-10-09 2009-08-24 제일약품주식회사 활성성분으로 시부트라민 유리염기를 함유하는 약제학적조성물 및 그 제조방법
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
PE20100254A1 (es) * 2008-06-06 2010-04-21 Boehringer Ingelheim Int Forma de dosificacion farmaceutica en capsula que comprende una formulacion en suspension de un derivado de indolinona
US8349353B2 (en) * 2008-06-27 2013-01-08 Otonomy, Inc. Controlled release cytotoxic agent compositions and methods for the treatment of otic disorders
UA107186C2 (xx) * 2008-12-03 2014-12-10 Тверді форми дозування бендамустину
PL2367542T3 (pl) * 2008-12-03 2014-05-30 Astellas Deutschland Gmbh Doustne formy dawkowania bendamustyny
US20100273730A1 (en) * 2009-04-27 2010-10-28 Innopharmax, Inc. Self-emulsifying pharmaceutical compositions of hydrophilic drugs and preparation thereof
EP2424506A1 (en) 2009-04-28 2012-03-07 Cephalon, Inc. Oral formulations of bendamustine
US20100297194A1 (en) * 2009-04-30 2010-11-25 Nathaniel Catron Formulation for oral administration of apoptosis promoter

Also Published As

Publication number Publication date
US10993933B2 (en) 2021-05-04
IL223311B (en) 2018-04-30
MY173873A (en) 2020-02-25
JO3587B1 (ar) 2020-07-05
NZ603872A (en) 2014-07-25
JP6373300B2 (ja) 2018-08-15
DK2575784T3 (en) 2018-10-15
ZA201208823B (en) 2014-01-29
SG186099A1 (en) 2013-01-30
EP2575784A1 (en) 2013-04-10
EA031793B1 (ru) 2019-02-28
JP2016153438A (ja) 2016-08-25
CO6640318A2 (es) 2013-03-22
AU2011260615B2 (en) 2016-11-17
KR20130086157A (ko) 2013-07-31
US20130202693A1 (en) 2013-08-08
US20150374670A1 (en) 2015-12-31
BR112012030654B1 (pt) 2021-11-09
PH12012502281A1 (en) 2013-02-11
JP6209446B2 (ja) 2017-10-04
WO2011151087A1 (en) 2011-12-08
BR112012030654A2 (pt) 2016-08-16
CA2800279A1 (en) 2011-12-08
CN103037851A (zh) 2013-04-10
KR101830142B1 (ko) 2018-02-20
TWI500431B (zh) 2015-09-21
JP2013527207A (ja) 2013-06-27
PH12012502281B1 (en) 2017-10-20
IL223311A0 (en) 2013-02-03
AR081835A1 (es) 2012-10-24
ES2690257T3 (es) 2018-11-20
EA201291104A1 (ru) 2013-06-28
CL2012003341A1 (es) 2013-06-28
AU2011260615A1 (en) 2013-01-10
TW201210635A (en) 2012-03-16
PT2575784T (pt) 2018-10-26
PL2575784T3 (pl) 2019-03-29
EP2575784B1 (en) 2018-08-08

Similar Documents

Publication Publication Date Title
MX2011005643A (es) Formas de dosificacion oral de bendamustina.
SG10201810985XA (en) Tofacitinib oral sustained release dosage forms
MX369121B (es) Formulacion farmaceutica acuosa de tapentadol para administracion oral.
JO3587B1 (ar) أشكال جرعات بينداموستين عن طريق الفم
MY177741A (en) Pharmaceutical compositions compring 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one-lactate monohydrate.
CY1118032T1 (el) Διεργασιες για την εμπορικη παρασκευη φαρμακευτικα δραστικου παραγοντα
IL222578A0 (en) Method for preparing pharmaceutical compositions intended for oral administration comprising one or more active ingredients and the compositions comprising same
WO2011101863A3 (en) Extended release pharmaceutical compositions of lacosamide
MX343689B (es) Formulaciones combinadas de darunavir.
WO2011019326A3 (en) Solubility and stability enchancing pharmaceutical formulation
MY152951A (en) Solid pharmaceutical fixed dose compositions comprising irbesartan and amlodipine, their preparation and their therapeutic application
MX341976B (es) Formulaciones de darunavir.
WO2012085284A3 (en) High drug load pharmaceutical formulations comprising dronedarone and its pharmaceutically acceptable salts
WO2012064302A3 (en) Improved montelukast formulations
MX346316B (es) Formulacion farmaceutica o nutraceutica.
WO2012085249A3 (en) Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts together with an organic acid
TR201803451T4 (tr) Olmesartan formülasyonlari.
EP3010534A4 (en) Pharmaceutical formulations and methods for oral delivery of biologically active ingredient
EP2409685A3 (en) Orally-disintegrating formulations of prasugrel
MX2012007393A (es) Composicion farmaceutica de disolucion rapida comprendiendo lornoxicam.
WO2013072770A3 (en) Pharmaceutical formulations comprising atorvastatin and glimepiride
UA110792C2 (uk) Лікарська форма бендамустину для перорального застосування
WO2012153347A3 (en) Oral pharmaceutical composition of olanzapine form 1 and sodium starch glycolate
UA97044C2 (ru) Средство противовирусной и иммуностимулирующей активности, способ получения средства противовирусной и иммуностимулирующей активности, способ профилактики и лечения инфекционных болезней
UA105513C2 (uk) Лікарська форма уповільненого вивільнення глюкозаміну

Legal Events

Date Code Title Description
FG Grant or registration