MX2012002529A - Agente terapeutico para trastornos de ansiedad. - Google Patents
Agente terapeutico para trastornos de ansiedad.Info
- Publication number
- MX2012002529A MX2012002529A MX2012002529A MX2012002529A MX2012002529A MX 2012002529 A MX2012002529 A MX 2012002529A MX 2012002529 A MX2012002529 A MX 2012002529A MX 2012002529 A MX2012002529 A MX 2012002529A MX 2012002529 A MX2012002529 A MX 2012002529A
- Authority
- MX
- Mexico
- Prior art keywords
- anxiety disorders
- therapeutic agent
- therapeutic
- pharmaceutically acceptable
- general formula
- Prior art date
Links
- 208000019901 Anxiety disease Diseases 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 150000007979 thiazole derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Se proporciona un agente para el tratamiento y/o profilaxis de un trastorno de ansiedad que comprende, como un ingrediente activo, un derivado de tiazol representado por la fórmula (I) en donde R1 representa arilo o similar, y R2 representa piridilo o similar, o una de sus sales farmacéuticamente aceptables, y similar.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009202894 | 2009-09-02 | ||
| PCT/JP2010/064989 WO2011027806A1 (ja) | 2009-09-02 | 2010-09-02 | 不安障害治療剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012002529A true MX2012002529A (es) | 2012-04-11 |
Family
ID=43649340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012002529A MX2012002529A (es) | 2009-09-02 | 2010-09-02 | Agente terapeutico para trastornos de ansiedad. |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US20120172362A1 (es) |
| EP (1) | EP2474544B1 (es) |
| JP (1) | JP5663485B2 (es) |
| KR (2) | KR20120047311A (es) |
| CN (1) | CN102482271A (es) |
| AU (1) | AU2010290424C1 (es) |
| BR (1) | BR112012004850A2 (es) |
| CA (1) | CA2772922C (es) |
| CL (1) | CL2012000533A1 (es) |
| CY (1) | CY1119483T1 (es) |
| DK (1) | DK2474544T3 (es) |
| DO (1) | DOP2012000056A (es) |
| EA (1) | EA023728B1 (es) |
| ES (1) | ES2643840T3 (es) |
| GE (1) | GEP20156225B (es) |
| HR (1) | HRP20171418T1 (es) |
| HU (1) | HUE036543T2 (es) |
| IL (1) | IL218320A (es) |
| LT (1) | LT2474544T (es) |
| MA (1) | MA33619B1 (es) |
| ME (1) | ME02877B (es) |
| MX (1) | MX2012002529A (es) |
| NZ (1) | NZ598754A (es) |
| PL (1) | PL2474544T3 (es) |
| PT (1) | PT2474544T (es) |
| RS (1) | RS56401B1 (es) |
| SI (1) | SI2474544T1 (es) |
| SM (1) | SMT201700465T1 (es) |
| TN (1) | TN2012000093A1 (es) |
| UA (1) | UA113383C2 (es) |
| WO (1) | WO2011027806A1 (es) |
| ZA (1) | ZA201202347B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2629414T3 (es) * | 2003-12-26 | 2017-08-09 | Kyowa Hakko Kirin Co., Ltd. | Derivados de tiazol |
| MA41090A (fr) * | 2014-12-03 | 2017-10-10 | H Lundbeck As | Antagoniste de a2a faiblement dosé pour le traitement du tdah et de la maladie de parkinson |
| JOP20200093A1 (ar) | 2015-01-09 | 2017-06-16 | Kyowa Kirin Co Ltd | طريقة لإنتاج مشتق ثيازول |
| JO3544B1 (ar) * | 2015-03-19 | 2020-07-05 | Kyowa Kirin Co Ltd | عامل علاجي للاختلال الوظيفي في الفص الجبهي |
| EA202190558A1 (ru) | 2018-09-17 | 2022-02-03 | Янгчжин Фарм. Ко., Лтд. | Новые производные тиазола и их фармацевтически приемлемые соли |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5543415A (en) | 1992-07-08 | 1996-08-06 | Kyowa Hakko Kogyo Co., Ltd. | Antidepressants |
| EP1016407B1 (en) | 1997-09-05 | 2006-05-10 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivatives for treating brain ischemia |
| WO2000069464A1 (en) * | 1999-05-12 | 2000-11-23 | Fujisawa Pharmaceutical Co., Ltd. | Novel use |
| US20040152659A1 (en) * | 1999-05-12 | 2004-08-05 | Fujisawa Pharmaceutical Co. Ltd. | Method for the treatment of parkinson's disease comprising administering an A1A2a receptor dual antagonist |
| JP2005516891A (ja) * | 2001-09-13 | 2005-06-09 | シェーリング コーポレイション | アデノシンＡ２ａレセプタアンタゴニストと抗鬱薬または抗不安薬との組合せ |
| US6620811B2 (en) | 2001-11-19 | 2003-09-16 | Hoffmann-La Roche Inc. | Isonicotin- and nicotinamide derivatives of benzothiazoles |
| US8202869B2 (en) * | 2003-06-10 | 2012-06-19 | Kyowa Hakko Kirin Co., Ltd. | Method of treating an anxiety disorder |
| ES2629414T3 (es) * | 2003-12-26 | 2017-08-09 | Kyowa Hakko Kirin Co., Ltd. | Derivados de tiazol |
| JPWO2006137527A1 (ja) * | 2005-06-23 | 2009-01-22 | 協和発酵キリン株式会社 | チアゾール誘導体 |
| US7928098B2 (en) | 2005-08-02 | 2011-04-19 | Kyowa Hakko Kirin Co., Ltd. | Therapeutic and/or preventive agents for a sleep disorder |
| UA110097C2 (uk) * | 2009-09-02 | 2015-11-25 | Терапевтичний агент для лікування розладів настрою |
-
2010
- 2010-02-09 UA UAA201203922A patent/UA113383C2/uk unknown
- 2010-09-02 SM SM20170465T patent/SMT201700465T1/it unknown
- 2010-09-02 LT LTEP10813754.8T patent/LT2474544T/lt unknown
- 2010-09-02 WO PCT/JP2010/064989 patent/WO2011027806A1/ja not_active Ceased
- 2010-09-02 PL PL10813754T patent/PL2474544T3/pl unknown
- 2010-09-02 HU HUE10813754A patent/HUE036543T2/hu unknown
- 2010-09-02 GE GEAP201012648A patent/GEP20156225B/en unknown
- 2010-09-02 ES ES10813754.8T patent/ES2643840T3/es active Active
- 2010-09-02 SI SI201031544T patent/SI2474544T1/sl unknown
- 2010-09-02 CA CA2772922A patent/CA2772922C/en not_active Expired - Fee Related
- 2010-09-02 ME MEP-2017-233A patent/ME02877B/me unknown
- 2010-09-02 DK DK10813754.8T patent/DK2474544T3/en active
- 2010-09-02 CN CN2010800392099A patent/CN102482271A/zh active Pending
- 2010-09-02 EP EP10813754.8A patent/EP2474544B1/en active Active
- 2010-09-02 PT PT108137548T patent/PT2474544T/pt unknown
- 2010-09-02 AU AU2010290424A patent/AU2010290424C1/en not_active Ceased
- 2010-09-02 JP JP2011529927A patent/JP5663485B2/ja not_active Expired - Fee Related
- 2010-09-02 US US13/393,068 patent/US20120172362A1/en not_active Abandoned
- 2010-09-02 MX MX2012002529A patent/MX2012002529A/es active IP Right Grant
- 2010-09-02 BR BR112012004850-3A patent/BR112012004850A2/pt not_active Application Discontinuation
- 2010-09-02 EA EA201270360A patent/EA023728B1/ru not_active IP Right Cessation
- 2010-09-02 KR KR1020127008310A patent/KR20120047311A/ko not_active Ceased
- 2010-09-02 NZ NZ598754A patent/NZ598754A/en not_active IP Right Cessation
- 2010-09-02 KR KR1020177010507A patent/KR20170044768A/ko not_active Ceased
- 2010-09-02 RS RS20170966A patent/RS56401B1/sr unknown
- 2010-09-02 HR HRP20171418TT patent/HRP20171418T1/hr unknown
-
2012
- 2012-02-26 IL IL218320A patent/IL218320A/en active IP Right Grant
- 2012-02-27 TN TNP2012000093A patent/TN2012000093A1/en unknown
- 2012-02-29 CL CL2012000533A patent/CL2012000533A1/es unknown
- 2012-03-01 DO DO2012000056A patent/DOP2012000056A/es unknown
- 2012-03-30 MA MA34734A patent/MA33619B1/fr unknown
- 2012-03-30 ZA ZA2012/02347A patent/ZA201202347B/en unknown
-
2017
- 2017-10-04 CY CY20171101029T patent/CY1119483T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |