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MX2012001790A - Anticuerpos monoclonales para proteina pbp2-a y secuencias homologas para el tratamiento de infecciones e inmunodiagnostico en bacterias del filum firmicutes. - Google Patents

Anticuerpos monoclonales para proteina pbp2-a y secuencias homologas para el tratamiento de infecciones e inmunodiagnostico en bacterias del filum firmicutes.

Info

Publication number
MX2012001790A
MX2012001790A MX2012001790A MX2012001790A MX2012001790A MX 2012001790 A MX2012001790 A MX 2012001790A MX 2012001790 A MX2012001790 A MX 2012001790A MX 2012001790 A MX2012001790 A MX 2012001790A MX 2012001790 A MX2012001790 A MX 2012001790A
Authority
MX
Mexico
Prior art keywords
pbp2
protein
monoclonal antibodies
bacteria
immunodiagnostics
Prior art date
Application number
MX2012001790A
Other languages
English (en)
Inventor
Jose Procopio Moreno Senna
Joao Luiz Sampaio Queiroz
Nadia Maria Batoreau
Maria De Gloria Martins Teixeira
Original Assignee
Fundacao Oswaldo Cruz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacao Oswaldo Cruz filed Critical Fundacao Oswaldo Cruz
Priority claimed from PCT/BR2010/000263 external-priority patent/WO2011017791A1/pt
Publication of MX2012001790A publication Critical patent/MX2012001790A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a anticuerpos monoclonales capaces de reconocer y unirse a la proteína PBP2a y otras proteínas presentando secuencias homólogas a PBP2a, incluyendo los patógenos Staphylococcus aureus resistentes a la meticilina - MRSA, Staphylococcus coagulasa-negativa, Staphylococcus sciuri, Enterococcus spp., y cualquier otra bacteria que posea PBP2a o secuencias homólogas a esta proteína; la invención todavía se refiere a la utilización de anticuerpos monoclonales capaces de reconocer y unirse a la proteína PBP2a y otras proteínas presentando secuencias homólogas a PBP2a en un inmunodiagnosis complementario para la detección de resistencia a beta-lactamas.
MX2012001790A 2009-08-10 2010-08-10 Anticuerpos monoclonales para proteina pbp2-a y secuencias homologas para el tratamiento de infecciones e inmunodiagnostico en bacterias del filum firmicutes. MX2012001790A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI0976200 2009-08-10
PCT/BR2010/000263 WO2011017791A1 (pt) 2009-08-10 2010-08-10 Anticorpos monoclonais para a proteína pbp2-a e sequências homólogas para o tratamento de infeçcões e imunodiagnóstico em bactérias do filo firmicutes

Publications (1)

Publication Number Publication Date
MX2012001790A true MX2012001790A (es) 2012-04-30

Family

ID=46208248

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012001790A MX2012001790A (es) 2009-08-10 2010-08-10 Anticuerpos monoclonales para proteina pbp2-a y secuencias homologas para el tratamiento de infecciones e inmunodiagnostico en bacterias del filum firmicutes.

Country Status (4)

Country Link
US (1) US8940304B2 (es)
EP (1) EP2476702B1 (es)
ES (1) ES2773920T3 (es)
MX (1) MX2012001790A (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014063703A1 (en) * 2012-10-22 2014-05-01 Statens Serum Institut Monoclonal antibodies
EP2889311B1 (en) 2013-12-30 2018-03-21 Albert-Ludwigs-Universität Freiburg Opsonic and protective monoclonal antibodies against gram-positive pathogens
EP3763737A1 (en) * 2019-07-12 2021-01-13 Eberhard Karls Universität Tübingen Binding compounds of penicillin binding protein 2 a

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8621910D0 (en) * 1986-09-11 1986-10-15 Technology Licence Co Ltd Monoclonal antibodies
EP1173485A1 (en) * 1999-05-03 2002-01-23 Medarex, Inc. Human antibodies to staphylococcus aureus
AU2006208226A1 (en) * 2005-01-24 2006-08-03 Amgen Inc. Humanized anti-amyloid antibody
FI118305B (fi) * 2006-03-24 2007-09-28 Metso Paper Inc Menetelmä ja sovitelma päällystemäärän hallitsemiseksi kuiturainan päällystyksessä

Also Published As

Publication number Publication date
US20120195907A1 (en) 2012-08-02
US8940304B2 (en) 2015-01-27
ES2773920T3 (es) 2020-07-15
EP2476702B1 (en) 2019-12-25
EP2476702A1 (en) 2012-07-18
EP2476702A4 (en) 2013-05-01

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