MX2012001693A - Formulaciones estables no corrosivas para inhaladores presurizados de dosis medida. - Google Patents
Formulaciones estables no corrosivas para inhaladores presurizados de dosis medida.Info
- Publication number
- MX2012001693A MX2012001693A MX2012001693A MX2012001693A MX2012001693A MX 2012001693 A MX2012001693 A MX 2012001693A MX 2012001693 A MX2012001693 A MX 2012001693A MX 2012001693 A MX2012001693 A MX 2012001693A MX 2012001693 A MX2012001693 A MX 2012001693A
- Authority
- MX
- Mexico
- Prior art keywords
- pressurized metered
- stable
- metered dose
- dose inhalers
- corrosive
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000009972 noncorrosive effect Effects 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 230000007797 corrosion Effects 0.000 abstract 1
- 238000005260 corrosion Methods 0.000 abstract 1
- 239000006184 cosolvent Substances 0.000 abstract 1
- 229940088679 drug related substance Drugs 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000375 suspending agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención se refiere a inhaladores farmacéuticos presurizados de dosis medida (IDM), que contienen al menos un haluro disuelto, una sustancia farmacéutica suspendida, una sustancia farmacéutica disuelta y un cosolvente, estabilizados químicamente y también contra la corrosión metálica mediante la adición de un ácido, un agente suspensor insaturado y agua.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/024,414 US20120204871A1 (en) | 2011-02-10 | 2011-02-10 | Stable, non-corrosive formulations for pressurized metered dose inhalers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2012001693A true MX2012001693A (es) | 2012-08-29 |
| MX353975B MX353975B (es) | 2018-02-07 |
Family
ID=45607025
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012001693A MX353975B (es) | 2011-02-10 | 2012-02-08 | Formulaciones estables no corrosivas para inhaladores presurizados de dosis medida. |
| MX2012003303A MX2012003303A (es) | 2011-02-10 | 2012-03-16 | Formulaciones medicinales en aerosol que no dañan la capa de ozono y con bajo efecto invernadero. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012003303A MX2012003303A (es) | 2011-02-10 | 2012-03-16 | Formulaciones medicinales en aerosol que no dañan la capa de ozono y con bajo efecto invernadero. |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20120204871A1 (es) |
| EP (1) | EP2486914A3 (es) |
| AR (1) | AR085059A1 (es) |
| BR (1) | BR102012002923A2 (es) |
| CL (1) | CL2012000327A1 (es) |
| DE (1) | DE102012102218A1 (es) |
| MX (2) | MX353975B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10610512B2 (en) | 2014-06-26 | 2020-04-07 | Island Breeze Systems Ca, Llc | MDI related products and methods of use |
| EP3174522A1 (en) | 2014-07-29 | 2017-06-07 | 3M Innovative Properties Company | Method of preparing a pharmaceutical composition |
| WO2016164508A1 (en) * | 2015-04-10 | 2016-10-13 | 3M Innovative Properties Company | Formulation and aerosol canisters, inhalers, and the like containing the formulation |
| WO2016187156A1 (en) * | 2015-05-21 | 2016-11-24 | Island Breeze Systems Ca, Llc | Propellant based metered dose inhaler and food applicators and applicators |
| EA202092976A1 (ru) * | 2018-06-04 | 2021-03-16 | Люпин Инк. | Устойчивые фармацевтические композиции для дозированных ингаляторов под давлением |
| IL305534A (en) * | 2021-03-23 | 2023-10-01 | 1232176 B C Ltd | device for the treatment of anaphylaxis |
| WO2025128797A1 (en) | 2023-12-13 | 2025-06-19 | Blue Evolution, Inc | Ecofriendly, biodegradable biological polysaccharide composition for packaging materials |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5766573A (en) | 1988-12-06 | 1998-06-16 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| DE4132176C2 (de) | 1991-09-27 | 1997-03-13 | Ig Spruehtechnik Gmbh | Dosieraerosole mit Isobutan als Treibmittel |
| ATE171865T1 (de) | 1991-12-12 | 1998-10-15 | Glaxo Group Ltd | Arzneimittel |
| RO117414B1 (ro) | 1992-12-09 | 2002-03-29 | Jager Paul D Waterbury | Compozitie farmaceutica de aerosol in solutie |
| US20060165606A1 (en) * | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6423298B2 (en) * | 1998-06-18 | 2002-07-23 | Boehringer Ingelheim Pharmaceuticals, Inc. | Pharmaceutical formulations for aerosols with two or more active substances |
| US6739333B1 (en) | 1999-05-26 | 2004-05-25 | Boehringer Ingelheim Pharma Kg | Stainless steel canister for propellant-driven metering aerosols |
| US6315985B1 (en) * | 1999-06-18 | 2001-11-13 | 3M Innovative Properties Company | C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability |
| SE0200312D0 (sv) | 2002-02-01 | 2002-02-01 | Astrazeneca Ab | Novel composition |
| ME00420B (me) * | 2003-03-20 | 2011-12-20 | Boehringer Ingelheim Pharmaceuticals Inc | Formulacija, za inhalator u kojem se odmjerava doza, u kojoj se kao propelenti koriste hidro-fluoro-alkani |
| AR041873A1 (es) * | 2003-10-30 | 2005-06-01 | Pablo Cassara Srl Lab | Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante |
| UA99466C2 (en) * | 2007-07-06 | 2012-08-27 | Гилиад Сайенсиз, Инк. | Crystalline pyridazine compound |
-
2011
- 2011-02-10 US US13/024,414 patent/US20120204871A1/en not_active Abandoned
- 2011-03-19 US US13/052,054 patent/US20120207685A1/en not_active Abandoned
-
2012
- 2012-02-07 AR ARP120100388A patent/AR085059A1/es unknown
- 2012-02-08 MX MX2012001693A patent/MX353975B/es active IP Right Grant
- 2012-02-08 CL CL2012000327A patent/CL2012000327A1/es unknown
- 2012-02-09 EP EP12154637A patent/EP2486914A3/en not_active Withdrawn
- 2012-02-09 BR BRBR102012002923-5A patent/BR102012002923A2/pt not_active IP Right Cessation
- 2012-03-16 MX MX2012003303A patent/MX2012003303A/es active IP Right Grant
- 2012-03-16 DE DE102012102218A patent/DE102012102218A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CL2012000327A1 (es) | 2014-07-11 |
| US20120204871A1 (en) | 2012-08-16 |
| AR085059A1 (es) | 2013-08-07 |
| MX2012003303A (es) | 2012-09-18 |
| DE102012102218A1 (de) | 2013-06-20 |
| MX353975B (es) | 2018-02-07 |
| US20120207685A1 (en) | 2012-08-16 |
| EP2486914A2 (en) | 2012-08-15 |
| BR102012002923A2 (pt) | 2013-07-23 |
| EP2486914A3 (en) | 2012-09-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |