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MX2012001552A - Moduladores de receptores de glutamato metabotropicos. - Google Patents

Moduladores de receptores de glutamato metabotropicos.

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Publication number
MX2012001552A
MX2012001552A MX2012001552A MX2012001552A MX2012001552A MX 2012001552 A MX2012001552 A MX 2012001552A MX 2012001552 A MX2012001552 A MX 2012001552A MX 2012001552 A MX2012001552 A MX 2012001552A MX 2012001552 A MX2012001552 A MX 2012001552A
Authority
MX
Mexico
Prior art keywords
receptor modulators
glutamate receptor
metabotropic glutamate
compounds
relates
Prior art date
Application number
MX2012001552A
Other languages
English (en)
Inventor
Markus Henrich
Tanja Weil
Valerjans Kauss
Ronalds Zemribo
Sibylle Mueller
Elina Erdmane
Mirko Hechenberger
Gints Smits
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of MX2012001552A publication Critical patent/MX2012001552A/es

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Abstract

Derivados heterocíclicos, así como sus sales farmacéuticamente aceptables. La invención se relaciona además con un proceso para la preparación de dichos compuestos. Los compuestos de la invención son moduladores de mGluR5 y por ello son de utilidad para el control y la prevención de trastornos neurológicos agudos y/o crónicos.
MX2012001552A 2009-08-05 2010-08-03 Moduladores de receptores de glutamato metabotropicos. MX2012001552A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27347909P 2009-08-05 2009-08-05
EP09251944 2009-08-05
PCT/EP2010/004749 WO2011015343A1 (en) 2009-08-05 2010-08-03 Metabotropic glutamate receptor modulators

Publications (1)

Publication Number Publication Date
MX2012001552A true MX2012001552A (es) 2012-03-29

Family

ID=41664577

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012001552A MX2012001552A (es) 2009-08-05 2010-08-03 Moduladores de receptores de glutamato metabotropicos.

Country Status (9)

Country Link
US (1) US20120178742A1 (es)
EP (1) EP2462142A1 (es)
JP (1) JP2013501013A (es)
CN (1) CN102471334A (es)
AR (1) AR077796A1 (es)
CA (1) CA2763956A1 (es)
MX (1) MX2012001552A (es)
TW (1) TW201116532A (es)
WO (1) WO2011015343A1 (es)

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WO2012152854A1 (en) * 2011-05-12 2012-11-15 Merz Pharma Gmbh & Co. Kgaa Metabotropic glutamate receptor modulators
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JP2016507537A (ja) 2013-02-07 2016-03-10 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 置換アセチレン誘導体およびｍＧｌｕＲ４の正のアロステリックモジュレーターとしてのそれらの使用
WO2015077246A1 (en) * 2013-11-19 2015-05-28 Vanderbilt University Substituted imidazopyridine and triazolopyridine compounds as negative allosteric modulators of mglur5
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JP6691127B2 (ja) * 2014-12-29 2020-04-28 レコルダーティ アイルランド リミテッドＲｅｃｏｒｄａｔｉ Ｉｒｅｌａｎｄ Ｌｉｍｉｔｅｄ ヘテロシクリルアルキン誘導体およびそれらのｍＧｌｕＲ５受容体のモジュレーターとしての使用
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